| MeSH term | MeSH ID | Detail |
|---|---|---|
| Peripheral Arterial Disease | D058729 | 7 associated lipids |
| Vascular System Injuries | D057772 | 2 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Stroke | D020521 | 32 associated lipids |
| Brain Infarction | D020520 | 17 associated lipids |
| Carotid Artery Injuries | D020212 | 8 associated lipids |
| Vasculitis | D014657 | 14 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Thromboangiitis Obliterans | D013919 | 4 associated lipids |
| Starvation | D013217 | 47 associated lipids |
lauric acid
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
Cross Reference
Introduction
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with lauric acid?
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with lauric acid
PubChem Associated disorders and diseases
What pathways are associated with lauric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with lauric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with lauric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with lauric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with lauric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with lauric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with lauric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Shet Ms et al. | The omega-hydroxlyation of lauric acid: oxidation of 12-hydroxlauric acid to dodecanedioic acid by a purified recombinant fusion protein containing P450 4A1 and NADPH-P450 reductase. | 1996 | Arch. Biochem. Biophys. | pmid:8651697 |
| Lewis DF | Essential requirements for substrate binding affinity and selectivity toward human CYP2 family enzymes. | 2003 | Arch. Biochem. Biophys. | pmid:12464242 |
| Puchkaev AV et al. | Aromatic stacking as a determinant of the thermal stability of CYP119 from Sulfolobus solfataricus. | 2003 | Arch. Biochem. Biophys. | pmid:12464244 |
| Kahn RA et al. | A conservative amino acid substitution alters the regiospecificity of CYP94A2, a fatty acid hydroxylase from the plant Vicia sativa. | 2001 | Arch. Biochem. Biophys. | pmid:11437349 |
| Loughran PA et al. | The kinetic and spectral characterization of the E. coli-expressed mammalian CYP4A7: cytochrome b5 effects vary with substrate. | 2001 | Arch. Biochem. Biophys. | pmid:11368012 |
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| Sharma P et al. | Structural basis of the binding of fatty acids to peptidoglycan recognition protein, PGRP-S through second binding site. | 2013 | Arch. Biochem. Biophys. | pmid:23149273 |
| Okita RT and Okita JR | Characterization of a cytochrome P450 from di(2-ethylhexyl) phthalate-treated rats which hydroxylates fatty acids. | 1992 | Arch. Biochem. Biophys. | pmid:1567203 |
| Cowart LA et al. | Structural determinants of active site binding affinity and metabolism by cytochrome P450 BM-3. | 2001 | Arch. Biochem. Biophys. | pmid:11368173 |
| Duncan T et al. | A glycoprotein binding retinoids and fatty acids is present in Drosophila. | 1994 | Arch. Biochem. Biophys. | pmid:8031123 |
| Gilep AA et al. | Reconstitution of the enzymatic activities of cytochrome P450s using recombinant flavocytochromes containing rat cytochrome b(5) fused to NADPH--cytochrome P450 reductase with various membrane-binding segments. | 2001 | Arch. Biochem. Biophys. | pmid:11396924 |
| Puchkaev AV and Ortiz de Montellano PR | The Sulfolobus solfataricus electron donor partners of thermophilic CYP119: an unusual non-NAD(P)H-dependent cytochrome P450 system. | 2005 | Arch. Biochem. Biophys. | pmid:15629120 |
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| Straub P et al. | Hydrophobic side chain requirements for lauric acid and progesterone hydroxylation at amino acid 113 in cytochrome P450 2C2, a potential determinant of substrate specificity. | 1993 | Arch. Biochem. Biophys. | pmid:8215458 |
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| Que Hee SS and Zainal H | Permeation of herbicidal dichlobenil from a Casoron formulation through nitrile gloves. | 2010 | Arch. Environ. Contam. Toxicol. | pmid:19855916 |
| Green PR and Geer BW | Changes in the fatty acid composition of Drosophila melanogaster during development and ageing. | 1979 | Arch. Int. Physiol. Biochim. | pmid:93438 |
| Demarne Y et al. | Comparison of long term lipogenic effects of two different medium-chain triglycerides (tri C8: O and tri C12 : O) in the growing rat. | 1978 | Arch. Int. Physiol. Biochim. | pmid:80196 |
| Demarne Y et al. | Effects of two different medium-chain triglycerides (tri C8:O and tri C12:O) on liver lipids in the growing rat. | 1978 | Arch. Int. Physiol. Biochim. | pmid:80984 |
| Jenkins CL et al. | Fatty acid composition of Simonsiella strains. | 1977 | Arch. Microbiol. | pmid:560178 |