lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with lauric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Misra A et al. | Characterization of cytochrome P450 monooxygenases isolated from trichome enriched fraction of Artemisia annua L. leaf. | 2012 | Gene | pmid:22986332 |
Dong S et al. | Cloning, characterization, and expression analysis of acyl-acyl carrier protein (ACP)-thioesterase B from seeds of Chinese Spicehush (Lindera communis). | 2014 | Gene | pmid:24631366 |
Ngo SN et al. | Cloning and expression of koala (Phascolarctos cinereus) liver cytochrome P450 CYP4A15. | 2006 | Gene | pmid:16677781 |
Orellana M et al. | Microsomal and peroxisomal fatty acid oxidation in streptozotocin diabetic rat liver. | 1997 | Gen. Pharmacol. | pmid:9068973 |
Orellana M et al. | Microsomal and peroxisomal fatty acid oxidation in bile duct ligated rats: a comparative study between liver and kidney. | 1997 | Gen. Pharmacol. | pmid:9147020 |
Orellana M et al. | Peroxisomal and microsomal fatty acid oxidation in liver of rats after chronic ethanol consumption. | 1998 | Gen. Pharmacol. | pmid:9809485 |
Boiteux-Antoine AF et al. | Comparative induction of drug-metabolizing enzymes by hypolipidaemic compounds. | 1989 | Gen. Pharmacol. | pmid:2502468 |
Ohashi M et al. | Anti-thrombotic effect of KC-404, a novel cerebral vasodilator. | 1986 | Gen. Pharmacol. | pmid:3093313 |
Lassman DJ et al. | Defining the role of cholecystokinin in the lipid-induced human brain activation matrix. | 2010 | Gastroenterology | pmid:20080096 |
Jørgensen JR et al. | In vivo absorption of medium-chain fatty acids by the rat colon exceeds that of short-chain fatty acids. | 2001 | Gastroenterology | pmid:11266379 |
Kim JJ and Sears DD | TLR4 and Insulin Resistance. | 2010 | Gastroenterol Res Pract | pmid:20814545 |
Takai H et al. | Construction and characterization of a Yarrowia lipolytica mutant lacking genes encoding cytochromes P450 subfamily 52. | 2012 | Fungal Genet. Biol. | pmid:22119766 |
Giera DD and van Lier RB | A convenient method for the determination of hepatic lauric acid omega-oxidation based on solvent partition. | 1991 | Fundam Appl Toxicol | pmid:2055365 |
Rolls ET | Chemosensory learning in the cortex. | 2011 | Front Syst Neurosci | pmid:21954379 |
Lihoreau M and Simpson SJ | Food, "culture," and sociality in Drosophila. | 2012 | Front Psychol | pmid:22654781 |
Benning UF et al. | New aspects of Phloem-mediated long-distance lipid signaling in plants. | 2012 | Front Plant Sci | pmid:22639651 |
Porporato PE et al. | Anticancer targets in the glycolytic metabolism of tumors: a comprehensive review. | 2011 | Front Pharmacol | pmid:21904528 |
Little TJ and Feinle-Bisset C | Oral and gastrointestinal sensing of dietary fat and appetite regulation in humans: modification by diet and obesity. | 2010 | Front Neurosci | pmid:21088697 |
Hervé D | Identification of a specific assembly of the g protein golf as a critical and regulated module of dopamine and adenosine-activated cAMP pathways in the striatum. | 2011 | Front Neuroanat | pmid:21886607 |
Berwick RC et al. | A Bird's Eye View of Human Language Evolution. | 2012 | Front Evol Neurosci | pmid:22518103 |
Hirschberg V et al. | Test systems to study the structure and function of uncoupling protein 1: a critical overview. | 2011 | Front Endocrinol (Lausanne) | pmid:22654819 |
Eskes GA et al. | Contribution of physical fitness, cerebrovascular reserve and cognitive stimulation to cognitive function in post-menopausal women. | 2010 | Front Aging Neurosci | pmid:21048898 |
Dev Kumar G and Micallef SA | Susceptibility of Salmonella enterica Isolates from Tomato Farm Environments to Fatty Acids Naturally Found on Tomato Fruit. | 2017 | Foodborne Pathog. Dis. | pmid:28398868 |
Choo SY et al. | Physicochemical and sensory properties of ice-cream formulated with virgin coconut oil. | 2010 | Food Sci Technol Int | pmid:21339169 |
Ohlsson L | Dairy products and plasma cholesterol levels. | 2010 | Food Nutr Res | pmid:20806084 |
Montanari C et al. | Synthesis of cyclopropane fatty acids in Lactobacillus helveticus and Lactobacillus sanfranciscensis and their cellular fatty acids changes following short term acid and cold stresses. | 2010 | Food Microbiol. | pmid:20417398 |
Coles L et al. | A model to predict the ATP equivalents of macronutrients absorbed from food. | 2013 | Food Funct | pmid:23233079 |
Catterall F et al. | Hepatic and intestinal cytochrome P450 and conjugase activities in rats treated with black tea theafulvins and theaflavins. | 2003 | Food Chem. Toxicol. | pmid:12842182 |
Hawkins DR et al. | Metabolism and pharmacokinetics of ethyl N(alpha)-lauroyl-L-arginate hydrochloride in human volunteers. | 2009 | Food Chem. Toxicol. | pmid:19651183 |
Burdock GA and Carabin IG | Safety assessment of myristic acid as a food ingredient. | 2007 | Food Chem. Toxicol. | pmid:17141389 |
Ouyang D et al. | A synergistic effect of Cu(2+) and norbixin on DNA damage. | 2008 | Food Chem. Toxicol. | pmid:18602206 |
Burattini S et al. | Anti-apoptotic activity of hydroxytyrosol and hydroxytyrosyl laurate. | 2013 | Food Chem. Toxicol. | pmid:23313337 |
Gibson WT and Teall MR | Interactions of C12 surfactants with the skin: studies on enzyme release and percutaneous absorption in vitro. | 1983 | Food Chem. Toxicol. | pmid:6686185 |
Ruckman SA et al. | Toxicological and metabolic investigations of the safety of N-alpha-lauroyl-L-arginine ethyl ester monohydrochloride (LAE). | 2004 | Food Chem. Toxicol. | pmid:14667471 |
Tan YN et al. | Purification and characterisation of antibacterial peptide-containing compound derived from palm kernel cake. | 2013 | Food Chem | pmid:23017424 |
Pan H et al. | Blend-modification of soy protein/lauric acid edible films using polysaccharides. | 2014 | Food Chem | pmid:24423494 |
Konkol LM et al. | Contaminants and levels of occurrence in washed and shredded poly(ethylene terephthalate) from curbside collection. Part 1: Extraction conditions. | 2003 | Food Addit Contam | pmid:13129782 |
Tiwari RP et al. | Effect of fatty acids on aflatoxin production by Aspergillus parasiticus. | 1986 | Folia Microbiol. (Praha) | pmid:3710316 |
Kacáni L et al. | Immunomodulatory effect of some amphiphilic detergents on the human promyelocytic HL-60 cells. | 1996 | Folia Biol. (Praha) | pmid:8831021 |
Mossi AJ et al. | Extraction and characterization of volatile compounds in Maytenus ilicifolia, using high-pressure CO2. | 2004 | Fitoterapia | pmid:15030921 |
Guo J and Friedman SL | Toll-like receptor 4 signaling in liver injury and hepatic fibrogenesis. | 2010 | Fibrogenesis Tissue Repair | pmid:20964825 |
Clément M et al. | Whey-derived free fatty acids suppress the germination of Candida albicans in vitro. | 2007 | FEMS Yeast Res. | pmid:17034417 |
Carreté R et al. | Inhibitory effect of sulfur dioxide and other stress compounds in wine on the ATPase activity of Oenococcus oeni. | 2002 | FEMS Microbiol. Lett. | pmid:12076806 |
Tsuge T et al. | Molecular cloning of two (R)-specific enoyl-CoA hydratase genes from Pseudomonas aeruginosa and their use for polyhydroxyalkanoate synthesis. | 2000 | FEMS Microbiol. Lett. | pmid:10713420 |
Han J et al. | Engineered Aeromonas hydrophila for enhanced production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) with alterable monomers composition. | 2004 | FEMS Microbiol. Lett. | pmid:15451119 |
Lu X et al. | Molecular cloning and functional analysis of two polyhydroxyalkanoate synthases from two strains of Aeromonas hydrophila spp. | 2005 | FEMS Microbiol. Lett. | pmid:15668013 |
Johnston NC et al. | Phospholipids of Clostridium perfringens: a reexamination. | 2004 | FEMS Microbiol. Lett. | pmid:15043870 |
Sun CQ et al. | Antibacterial actions of fatty acids and monoglycerides against Helicobacter pylori. | 2003 | FEMS Immunol. Med. Microbiol. | pmid:12727360 |
Sun CQ et al. | The products from lipase-catalysed hydrolysis of bovine milkfat kill Helicobacter pylori in vitro. | 2007 | FEMS Immunol. Med. Microbiol. | pmid:17328757 |
Aussel L et al. | Novel variation of lipid A structures in strains of different Yersinia species. | 2000 | FEBS Lett. | pmid:10620712 |
Antoun J et al. | CYP4A11 is repressed by retinoic acid in human liver cells. | 2006 | FEBS Lett. | pmid:16712844 |
Casolo V et al. | The role of mild uncoupling and non-coupled respiration in the regulation of hydrogen peroxide generation by plant mitochondria. | 2000 | FEBS Lett. | pmid:10828450 |
Maves SA et al. | Decreased substrate affinity upon alteration of the substrate-docking region in cytochrome P450(BM-3). | 1997 | FEBS Lett. | pmid:9315688 |
Salaün JP et al. | Stereochemistry of oxidized fatty acids generated during catalytic oxygenation of lauric acid and unsaturated analogs by plant microsomes. | 1992 | FEBS Lett. | pmid:1607005 |
Keereetaweep J et al. | Lauroylethanolamide is a potent competitive inhibitor of lipoxygenase activity. | 2010 | FEBS Lett. | pmid:20541546 |
Borlakoglu JT et al. | Evidence for the induction of cytochrome P-452 in rat liver by Aroclor 1254, a commercial mixture of polychlorinated biphenyls. | 1989 | FEBS Lett. | pmid:2497034 |
Imai Y and Nakamura M | The importance of threonine-301 from cytochromes P-450 (laurate (omega-1)-hydroxylase and testosterone 16 alpha-hydroxylase) in substrate binding as demonstrated by site-directed mutagenesis. | 1988 | FEBS Lett. | pmid:3134259 |
Sauveplane V et al. | Arabidopsis thaliana CYP77A4 is the first cytochrome P450 able to catalyze the epoxidation of free fatty acids in plants. | 2009 | FEBS J. | pmid:19120447 |
Gao S et al. | Identification of two late acyltransferase genes responsible for lipid A biosynthesis in Moraxella catarrhalis. | 2008 | FEBS J. | pmid:18795947 |
Kandel S et al. | Characterization of a methyl jasmonate and wounding-responsive cytochrome P450 of Arabidopsis thaliana catalyzing dicarboxylic fatty acid formation in vitro. | 2007 | FEBS J. | pmid:17868380 |
Doolan GK et al. | Fatty acid augmentation of the cardiac slowly activating delayed rectifier current (IKs) is conferred by hminK. | 2002 | FASEB J. | pmid:12206993 |
Cometti A et al. | Isolation and structure determination of the main related substances of teicoplanin, a glycopeptide antibiotic. | 1988 | Farmaco Sci | pmid:2977757 |
Blais ME and Rowland-Jones S | Lessons from the failure of the adenovector HIV vaccine. | 2009 | F1000 Biol Rep | pmid:20948634 |
Royter M et al. | Thermostable lipases from the extreme thermophilic anaerobic bacteria Thermoanaerobacter thermohydrosulfuricus SOL1 and Caldanaerobacter subterraneus subsp. tengcongensis. | 2009 | Extremophiles | pmid:19579003 |
Levade T et al. | Enhancement of fluorescence of pyrene-containing lipids by polar media, detergents and phospholipids. | 1987 | Experientia | pmid:3653339 |
Lupp A et al. | Fibrates and their newly synthesized glycinate or glycinate-methylester derivatives: comparison of the interactions with liver cytochrome P450 dependent monooxygenase- and oxidase-functions in vitro. | 2003 | Exp. Toxicol. Pathol. | pmid:12877356 |
Eisinger K et al. | Lipidomic analysis of the liver from high-fat diet induced obese mice identifies changes in multiple lipid classes. | 2014 | Exp. Mol. Pathol. | pmid:24830603 |
Rundle DR et al. | Characterization of Type I and Type II myristoyl-CoA:protein N-myristoyltransferases with the Acyl-CoAs found on heterogeneously acylated retinal proteins. | 2002 | Exp. Eye Res. | pmid:12123640 |
Fibach E et al. | Uptake of fluorescent fatty acids by erythroleukemia cells. Effect of differentiation. | 1986 | Exp. Cell Res. | pmid:3462004 |
Zakaria ZA et al. | Hepatoprotective activity of dried- and fermented-processed virgin coconut oil. | 2011 | Evid Based Complement Alternat Med | pmid:21318140 |
Arora R et al. | Potential of Complementary and Alternative Medicine in Preventive Management of Novel H1N1 Flu (Swine Flu) Pandemic: Thwarting Potential Disasters in the Bud. | 2011 | Evid Based Complement Alternat Med | pmid:20976081 |
Mashelkar RA | Second World Ayurveda Congress (Theme: Ayurveda for the Future)-Inaugural Address: Part II. | 2008 | Evid Based Complement Alternat Med | pmid:18830457 |
Uemura T et al. | Effect of YM-254890, a specific Galphaq/11 inhibitor, on experimental peripheral arterial disease in rats. | 2006 | Eur. J. Pharmacol. | pmid:16566917 |
Ogawa T et al. | Effects of prasugrel, a novel P2Y(12) inhibitor, in rat models of cerebral and peripheral artery occlusive diseases. | 2009 | Eur. J. Pharmacol. | pmid:19356727 |
Yano K et al. | Demonstration of elevation and localization of Rho-kinase activity in the brain of a rat model of cerebral infarction. | 2008 | Eur. J. Pharmacol. | pmid:18703046 |
Veeresh Babu SV et al. | Lauric acid and myristic acid prevent testosterone induced prostatic hyperplasia in rats. | 2010 | Eur. J. Pharmacol. | pmid:19786012 |
Kolesnikov Y and Sõritsa D | Analgesic synergy between topical opioids and topical non-steroidal anti-inflammatory drugs in the mouse model of thermal pain. | 2008 | Eur. J. Pharmacol. | pmid:18001710 |
Droese W et al. | Questions to the supply of young infants with fat and fatty acids. II. Fat content and fatty acid pattern in milk formulae for healthy infants in the first 6 months of life. | 1976 | Eur. J. Pediatr. | pmid:1036483 |
Wanten GJ et al. | Saturated triglycerides and fatty acids activate neutrophils depending on carbon chain-length. | 2002 | Eur. J. Clin. Invest. | pmid:11952815 |
Bekkers AC et al. | Targeting of porcine pancreatic phospholipase A2 to human platelets. Introduction of an RGD sequence and acyl-group by chemical modification. | 1996 | Eur. J. Biochem. | pmid:8665954 |
Wollenweber HW et al. | Fatty acid in lipopolysaccharides of Salmonella species grown at low temperature. Identification and position. | 1983 | Eur. J. Biochem. | pmid:6825685 |
Salaün JP et al. | Induction and specificity of a (cytochrome P-450)-dependent laurate in-chain-hydroxylase from higher plant microsomes. | 1981 | Eur. J. Biochem. | pmid:7308207 |
Zimmer T et al. | Mutual conversion of fatty-acid substrate specificity by a single amino-acid exchange at position 527 in P-450Cm2 and P-450Alk3A. | 1998 | Eur. J. Biochem. | pmid:9760180 |
Pedersen AO et al. | Laurate binding to human serum albumin. Multiple binding equilibria investigated by a dialysis exchange method. | 1986 | Eur. J. Biochem. | pmid:3948866 |
Pedersen AO et al. | Effects of ionic strength and pH on the binding of medium-chain fatty acids to human serum albumin. | 1995 | Eur. J. Biochem. | pmid:7588780 |
Takabayashi K et al. | Coupling between fatty acid binding and sulfhydryl oxidation in bovine serum albumin. | 1983 | Eur. J. Biochem. | pmid:6628382 |
Weisshaar R and Lingens F | The lipopolysaccharide of a chloridazon-degrading bacterium. | 1983 | Eur. J. Biochem. | pmid:6653551 |
Lee I and Kadenbach B | Palmitate decreases proton pumping of liver-type cytochrome c oxidase. | 2001 | Eur. J. Biochem. | pmid:11737187 |
Akesson B et al. | Influence of chain length and unsaturation on the effects of fatty acids on phosphoglyceride biosynthesis in isolated rat and pig hepatocytes. | 1976 | Eur. J. Biochem. | pmid:1261548 |
Pedersen AO et al. | Thermodynamic parameters for binding of fatty acids to human serum albumin. | 1990 | Eur. J. Biochem. | pmid:2373077 |
Salaün JP et al. | A microsomal (cytochrome P-450)-linked lauric-acid-monooxygenase from aged Jerusalem-artichoke-tuber tissues. | 1978 | Eur. J. Biochem. | pmid:710415 |
Cresteil T et al. | Immunoquantification of epoxide hydrolase and cytochrome P-450 isozymes in fetal and adult human liver microsomes. | 1985 | Eur. J. Biochem. | pmid:2411555 |
Sharma RK et al. | Differential induction of peroxisomal and microsomal fatty-acid-oxidising enzymes by peroxisome proliferators in rat liver and kidney. Characterisation of a renal cytochrome P-450 and implications for peroxisome proliferation. | 1989 | Eur. J. Biochem. | pmid:2776771 |
Sumimoto J et al. | Characterization of human neutrophil leukotriene B4 omega-hydroxylase as a system involving a unique cytochrome P-450 and NADPH-cytochrome P-450 reductase. | 1988 | Eur. J. Biochem. | pmid:3127205 |
Lehmann V and Benninghoff B | Isolation of a mutant from Salmonella typhimurium producing acyl-deficient lipopolysaccharides. | 1988 | Eur. J. Biochem. | pmid:3061817 |
De Cuyper M and Joniau M | Magnetoliposomes. Formation and structural characterization. | 1988 | Eur. Biophys. J. | pmid:3366097 |
Liebau M et al. | Bioadhesion of supramolecular structures at supported planar bilayers as studied by the quartz crystal microbalance. | 2001 | Eur. Biophys. J. | pmid:11372532 |
Sivakumar R et al. | Oviposition attractancy of dodecanoic, hexadecanoic and tetradecanoic acids against Aedes aegypti and Culex quinquefasciatus (Diptera: Culicidae). | 2011 | Eur Rev Med Pharmacol Sci | pmid:22165678 |
Akpinar E et al. | Lyotropic mixture made of potassium laurate/1-undecanol/K2SO4/water presenting high birefringences and large biaxial nematic phase domain: a laser conoscopy study. | 2012 | Eur Phys J E Soft Matter | pmid:22718499 |
Christiansen A et al. | Effects of non-ionic surfactants on in vitro triglyceride digestion and their susceptibility to digestion by pancreatic enzymes. | 2010 | Eur J Pharm Sci | pmid:20633646 |