lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with lauric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Alves NF et al. | Acute Treatment with Lauric Acid Reduces Blood Pressure and Oxidative Stress in Spontaneously Hypertensive Rats. | 2017 | Basic Clin. Pharmacol. Toxicol. | pmid:28054477 |
Stark K et al. | Expression of CYP4F12 in gastrointestinal and urogenital epithelia. | 2004 | Basic Clin. Pharmacol. Toxicol. | pmid:15078342 |
Russell VA et al. | Animal models of attention-deficit hyperactivity disorder. | 2005 | Behav Brain Funct | pmid:16022733 |
Hu H et al. | A novel class of antagonists for the FFAs receptor GPR40. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19818732 |
Imaoka S and Funae Y | Purification and NH2-terminal sequence of cytochrome P-450 from kidney microsomes of untreated male rats. | 1986 | Biochem. Biophys. Res. Commun. | pmid:3801020 |
Alterman MA et al. | Heteroatom substitution shifts regioselectivity of lauric acid metabolism from omega-hydroxylation to (omega-1)-oxidation. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7575514 |
Björkhem I | On the mechanism of 11-hydroxylation of lauric acid by rat liver microsomes. | 1973 | Biochem. Biophys. Res. Commun. | pmid:4689066 |
Imai Y and Nakamura M | Point mutations at threonine-301 modify substrate specificity of rabbit liver microsomal cytochromes P-450 (laurate (omega-1)-hydroxylase and testosterone 16 alpha-hydroxylase). | 1989 | Biochem. Biophys. Res. Commun. | pmid:2493247 |
Imaoka S et al. | A transgenic mouse expressing human CYP4B1 in the liver. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11396967 |
Helvig C et al. | Drosophila melanogaster CYP6A8, an insect P450 that catalyzes lauric acid (omega-1)-hydroxylation. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15555597 |