lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

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Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Peripheral Arterial Disease D058729 7 associated lipids
Vascular System Injuries D057772 2 associated lipids
Atherosclerosis D050197 85 associated lipids
Stroke D020521 32 associated lipids
Brain Infarction D020520 17 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Vasculitis D014657 14 associated lipids
Thrombosis D013927 49 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Starvation D013217 47 associated lipids
Seizures D012640 87 associated lipids
Prostatic Hyperplasia D011470 20 associated lipids
Obesity, Morbid D009767 8 associated lipids
Nephrosis, Lipoid D009402 2 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Lung Neoplasms D008175 171 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

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Per page 10 20 50 100 | Total 1837
Authors Title Published Journal PubMed Link
Ayala-Bravo HA et al. Effects of sucrose oleate and sucrose laureate on in vivo human stratum corneum permeability. 2003 Pharm. Res. pmid:12948025
Jain AK and Panchagnula R Transdermal drug delivery of tricyclic antidepressants: effect of fatty acids. Methods Find Exp Clin Pharmacol pmid:12949625
BEAN HS and BERRY H The bactericidal activity of phenols in aqueous solutions of soap. III. The bactericidal activity of chloroxylenol in aqueous solutions of potassium laurate. 1953 J. Pharm. Pharmacol. pmid:13085294
Konkol LM et al. Contaminants and levels of occurrence in washed and shredded poly(ethylene terephthalate) from curbside collection. Part 1: Extraction conditions. 2003 Food Addit Contam pmid:13129782
VAN DE KAMER JH et al. Gas-liquid partition chromatography: the separation and micro-estimation of volatile fatty acids from formic acid to dodecanoic acid. 1955 Biochem. J. pmid:13260193
van Wijk GM et al. Antiviral nucleoside diphosphate diglycerides: improved synthesis and facilitated purification. 1992 J. Lipid Res. pmid:1331283
CARLESS JE and NIXON JR The oxidation of solubilised and emulsified oils. I. Oxidation of benzaldehyde in potassium laurate and cetomacrogol dispersions. 1957 J. Pharm. Pharmacol. pmid:13492185
Adachi H et al. Inhibitory effect of prostaglandin E1 on laurate-induced peripheral vascular occlusive sequelae in rabbits: optimized topical formulation with beta-cyclodextrin derivative and penetration enhancer HPE-101. 1992 J. Pharm. Pharmacol. pmid:1361553
BLANK IH and GOULD E Penetration of anionic surfactants (surface active agents) into skin. I. Penetration of sodium laurate and sodium dodecyl sulfate into excised human skin. 1959 J. Invest. Dermatol. pmid:13801318
CARLESS JE and NIXON JR The oxidation of solubilised and emulsified oils. Part II. Solubility of benzaldehyde, cyclohexene and methyl linoleate in potassium laurate and cetomacrogol solutions. 1960 J. Pharm. Pharmacol. pmid:13807716
CARLESS JE and NIXON JR The oxidation of solubilised and emulsified oils. Part III. The oxidation of methyl linoleate in potassium laurate and cetomacrogol dispersions. 1960 J. Pharm. Pharmacol. pmid:13807717
Knickle LC et al. The suppression of hepatic cytochrome P4504A mRNA mediated by the interferon inducer polyinosinic acid.polycytidylic acid. 1992 Biochem. Pharmacol. pmid:1380810
BLANK IH and GOULD E Penetration of anionic surfactants into skin. III. Penetration from buffered sodium laurate solutions. 1961 J. Invest. Dermatol. pmid:13869837
Komata Y et al. In vitro percutaneous absorption of thiamine disulfide from a mixture of propylene glycol and fatty acid. 1992 J Pharm Sci pmid:1403716
Skottová N et al. Effect of premature weaning on the fatty acid composition of rat adipose tissue. 1977 Physiol Bohemoslov pmid:140394
Denke MA and Grundy SM Comparison of effects of lauric acid and palmitic acid on plasma lipids and lipoproteins. 1992 Am. J. Clin. Nutr. pmid:1415008
Miko M and Devínsky F Biochemical basis of cytotoxic activity of some new N'-oxides of N',N'-dimethylaminoalkylamides of dodecanoic acid. 1992 Drug Metabol Drug Interact pmid:1424644
Brown JN and Smith TM Inhibition of key glycolytic enzymes from rabbit kidney medulla by free fatty acids in vitro. 1977 Enzyme pmid:142634
Naidu KA Vitamin C in human health and disease is still a mystery? An overview. 2003 Nutr J pmid:14498993
Ströhle A [Experimental provocation of panic attacks as a human experimental model for anxiety]. 2003 Nervenarzt pmid:14504770