| MeSH term | MeSH ID | Detail |
|---|---|---|
| Peripheral Arterial Disease | D058729 | 7 associated lipids |
| Vascular System Injuries | D057772 | 2 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Stroke | D020521 | 32 associated lipids |
| Brain Infarction | D020520 | 17 associated lipids |
| Carotid Artery Injuries | D020212 | 8 associated lipids |
| Vasculitis | D014657 | 14 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Thromboangiitis Obliterans | D013919 | 4 associated lipids |
| Starvation | D013217 | 47 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Prostatic Hyperplasia | D011470 | 20 associated lipids |
| Obesity, Morbid | D009767 | 8 associated lipids |
| Nephrosis, Lipoid | D009402 | 2 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Malabsorption Syndromes | D008286 | 16 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Liver Diseases, Alcoholic | D008108 | 13 associated lipids |
| Leukemia, Myeloid | D007951 | 52 associated lipids |
lauric acid
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
Cross Reference
Introduction
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with lauric acid?
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Am. J. Clin. Nutr. (1)
- Am. J. Physiol. Heart Circ. Physiol. (1)
- Antimicrob. Agents Chemother. (1)
- Others (7)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with lauric acid
PubChem Associated disorders and diseases
What pathways are associated with lauric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with lauric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with lauric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with lauric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with lauric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with lauric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with lauric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hu H et al. | A novel class of antagonists for the FFAs receptor GPR40. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19818732 |
| Imaoka S et al. | Induction of renal cytochrome P-450 in hepatic microsomes of diabetic rats. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3365247 |
| Roomi MW et al. | Decreased expression of cytochrome P-452 in the resistance phenotype characteristic of putative preneoplastic hepatocyte nodules during hepatocarcinogenesis. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3365259 |
| Liu K et al. | Isolation and biochemical characterization of two lipases from a metagenomic library of China Holstein cow rumen. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19486892 |
| Alterman MA et al. | Heteroatom substitution shifts regioselectivity of lauric acid metabolism from omega-hydroxylation to (omega-1)-oxidation. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7575514 |
| Kiffel L et al. | Purification and characterization of a cytochrome P-450 isozyme isolated from the liver of rats pretreated with clofibrate. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3140811 |
| Björkhem I | On the mechanism of 11-hydroxylation of lauric acid by rat liver microsomes. | 1973 | Biochem. Biophys. Res. Commun. | pmid:4689066 |
| Björkhem I and Hamberg M | On the rate-limiting step in W-hydroxylation of lauric acid. | 1972 | Biochem. Biophys. Res. Commun. | pmid:4662395 |
| Kato A and Arima K | Inhibitory effect of sucrose ester of lauric acid on the growth of Escherichia coli. | 1971 | Biochem. Biophys. Res. Commun. | pmid:5543940 |
| Miranda CL et al. | Regiospecificity in the hydroxylation of lauric acid by rainbow trout hepatic cytochrome P450 isozymes. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2403346 |
| Amet Y et al. | Evidence that cytochrome P450 2E1 is involved in the (omega-1)-hydroxylation of lauric acid in rat liver microsomes. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8093035 |
| Imaoka S et al. | A transgenic mouse expressing human CYP4B1 in the liver. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11396967 |
| Helvig C et al. | Drosophila melanogaster CYP6A8, an insect P450 that catalyzes lauric acid (omega-1)-hydroxylation. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15555597 |
| Tanaka T et al. | Saturated and trans-unsaturated fatty acids elicit high levels of superoxide generation in intact and cell-free preparations of neutrophils. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3034258 |
| Pinot F et al. | New cytochrome P450-dependent reactions from wheat: terminal and sub-terminal hydroxylation of oleic acid by microsomes from naphthalic acid anhydride and phenobarbital induced wheat seedlings. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8297392 |
| Yoshimoto M et al. | Purification and characterization of two forms of cytochrome P-450 from rat kidney cortex microsomes. | 1986 | Biochem. Int. | pmid:3814156 |
| Takahashi K et al. | Ester synthesis at extraordinarily low temperature of -3 degrees C by modified lipase in benzene. | 1985 | Biochem. Int. | pmid:3927919 |
| Tambo F et al. | Auto-oxidation of Lingula unguis and Siphonosoma cumanense hemerythrins induced by some perturbants. | 1989 | Biochem. Int. | pmid:2764951 |
| Imaoka S et al. | Omega- and (omega-1)-hydroxylation of lauric acid and arachidonic acid by rat renal cytochrome P-450. | 1989 | Biochem. Int. | pmid:2504167 |
| Dahlbäck H and Wikvall K | 25-Hydroxylation of vitamin D3 by a cytochrome P-450 from rabbit liver mitochondria. | 1988 | Biochem. J. | pmid:2844144 |
| Rottensteiner H et al. | The peroxisomal transporter gene ANT1 is regulated by a deviant oleate response element (ORE): characterization of the signal for fatty acid induction. | 2002 | Biochem. J. | pmid:12071844 |
| Whiting P and Dinan L | Formation of apolar ecdysteroid conjugates by ovaries of the house cricket Acheta domesticus in vitro. | 1988 | Biochem. J. | pmid:3421912 |
| Girvan HM et al. | Novel haem co-ordination variants of flavocytochrome P450BM3. | 2009 | Biochem. J. | pmid:18721129 |
| Gibson GG et al. | Cytochrome P-450 induction by clofibrate. Purification and properties of a hepatic cytochrome P-450 relatively specific for the 12- and 11-hydroxylation of dodecanoic acid (lauric acid). | 1982 | Biochem. J. | pmid:7103935 |
| Hasegawa K et al. | Growth of beta(2)-microglobulin-related amyloid fibrils by non-esterified fatty acids at a neutral pH. | 2008 | Biochem. J. | pmid:18637792 |
| Radom J et al. | Influence of chain length of pyrene fatty acids on their uptake and metabolism by Epstein-Barr-virus-transformed lymphoid cell lines from a patient with multisystemic lipid storage myopathy and from control subjects. | 1990 | Biochem. J. | pmid:2165389 |
| Sandercock SP and Russell NJ | The elongation of exogenous fatty acids and the control of phospholipid acyl chain length in Micrococcus cryophilus. | 1980 | Biochem. J. | pmid:7470022 |
| VAN DE KAMER JH et al. | Gas-liquid partition chromatography: the separation and micro-estimation of volatile fatty acids from formic acid to dodecanoic acid. | 1955 | Biochem. J. | pmid:13260193 |
| Sohlenius AK et al. | The effects of perfluoro-octanoic acid on hepatic peroxisome proliferation and related parameters show no sex-related differences in mice. | 1992 | Biochem. J. | pmid:1497616 |
| JAMES AT and MARTIN AJ | Gas-liquid partition chromatography; the separation and micro-estimation of volatile fatty acids from formic acid to dodecanoic acid. | 1952 | Biochem. J. | pmid:14934673 |
| Girvan HM et al. | Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3. | 2010 | Biochem. J. | pmid:20180779 |
| Lind KE and Moller JV | Ligand-apomyoglobin interactions. Configurational adaptability of the haem-binding site. | 1976 | Biochem. J. | pmid:949328 |
| Muller DN et al. | Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation. | 2007 | Biochem. J. | pmid:17112342 |
| Kragh-Hansen U et al. | High-affinity binding of laurate to naturally occurring mutants of human serum albumin and proalbumin. | 1996 | Biochem. J. | pmid:9003380 |
| Bergman T and Postlind H | Characterization of pig kidney microsomal cytochrome P-450 catalysing 25-hydroxylation of vitamin D3 and C27 steroids. | 1990 | Biochem. J. | pmid:2169238 |
| Cunningham VJ et al. | The binding of L-tryptophan to serum albumins in the presence of non-esterified fatty acids. | 1975 | Biochem. J. | pmid:1147909 |
| Benveniste I et al. | Immunochemical characterization of NADPH-cytochrome P-450 reductase from Jerusalem artichoke and other higher plants. | 1989 | Biochem. J. | pmid:2499315 |
| Lundell K | Cloning and expression of two novel pig liver and kidney fatty acid hydroxylases [cytochrome P450 (CYP)4A24 and CYP4A25]. | 2002 | Biochem. J. | pmid:11931657 |
| Magdalou J et al. | Effect of 1-benzylimidazole on cytochromes P-450 induction and on the activities of epoxide hydrolases and UDP-glucuronosyltransferases in rat liver. | 1988 | Biochem. Pharmacol. | pmid:2840913 |
| Amet Y et al. | Validation of the (omega-1)-hydroxylation of lauric acid as an in vitro substrate probe for human liver CYP2E1. | 1995 | Biochem. Pharmacol. | pmid:8615855 |
| Ronis MJ et al. | Induction, suppression and inhibition of multiple hepatic cytochrome P450 isozymes in the male rat and bobwhite quail (Colinus virginianus) by ergosterol biosynthesis inhibiting fungicides (EBIFs). | 1994 | Biochem. Pharmacol. | pmid:7986207 |
| Sharma R et al. | Co-induction of microsomal cytochrome P-452 and the peroxisomal fatty acid beta-oxidation pathway in the rat by clofibrate and di-(2-ethylhexyl)phthalate. Dose-response studies. | 1988 | Biochem. Pharmacol. | pmid:3355594 |
| De Matteis F et al. | Peroxidase-like activity of uncoupled cytochrome P450: studies with bilirubin and toxicological implications of uncoupling. | 2012 | Biochem. Pharmacol. | pmid:22564776 |
| Bains SK et al. | Immunochemical study on the contribution of hypolipidaemic-induced cytochrome P-452 to the metabolism of lauric acid and arachidonic acid. | 1985 | Biochem. Pharmacol. | pmid:3929789 |
| Hornung B et al. | Medium chain length fatty acids stimulate triacylglycerol synthesis in tissue culture cells. | 1992 | Biochem. Pharmacol. | pmid:1739406 |
| Sivapathasundaram S et al. | A study of the expression of the xenobiotic-metabolising cytochrome P450 proteins and of testosterone metabolism in bovine liver. | 2001 | Biochem. Pharmacol. | pmid:11585060 |
| Amet Y et al. | Cytochrome P450 4A and 2E1 expression in human kidney microsomes. | 1997 | Biochem. Pharmacol. | pmid:9113097 |
| Okita RT et al. | Lauric acid hydroxylation in human liver and kidney cortex microsomes. | 1979 | Biochem. Pharmacol. | pmid:533546 |
| Kocarek TA and Feller DR | Quantitative assessment of enzyme induction by peroxisome proliferators and application to determination of effects on triglyceride biosynthesis in primary cultures of rat hepatocytes. | 1989 | Biochem. Pharmacol. | pmid:2597188 |
| Kitagawa S et al. | Effects of alkyl gallates on P-glycoprotein function. | 2005 | Biochem. Pharmacol. | pmid:16139251 |