| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Prostatic Hyperplasia | D011470 | 20 associated lipids |
| Brain Infarction | D020520 | 17 associated lipids |
| Stroke | D020521 | 32 associated lipids |
| Starvation | D013217 | 47 associated lipids |
| Leukemia, Myeloid | D007951 | 52 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Cerebrovascular Disorders | D002561 | 25 associated lipids |
| Cerebral Infarction | D002544 | 6 associated lipids |
| Liver Diseases, Alcoholic | D008108 | 13 associated lipids |
lauric acid
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
Cross Reference
Introduction
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with lauric acid?
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with lauric acid
PubChem Associated disorders and diseases
What pathways are associated with lauric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with lauric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with lauric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with lauric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with lauric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with lauric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with lauric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Temme EH et al. | Comparison of the effects of diets enriched in lauric, palmitic, or oleic acids on serum lipids and lipoproteins in healthy women and men. | 1996 | Am. J. Clin. Nutr. | pmid:8644684 |
| Bambal RB and Hanzlik RP | Active site structure and substrate specificity of cytochrome P450 4A1: steric control of ligand approach perpendicular to heme plane. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8605007 |
| Hiratsuka M et al. | Effects of gonadectomy and sex hormones on the induction of hepatic CYP4A by clofibrate in rats. | 1996 | Biol. Pharm. Bull. | pmid:8820907 |
| Kacáni L et al. | Immunomodulatory effect of some amphiphilic detergents on the human promyelocytic HL-60 cells. | 1996 | Folia Biol. (Praha) | pmid:8831021 |
| Constantinides PP et al. | Water-in-oil microemulsions containing medium-chain fatty acids/salts: formulation and intestinal absorption enhancement evaluation. | 1996 | Pharm. Res. | pmid:8932438 |
| Wang MH et al. | Cloning, sequencing, and cDNA-directed expression of the rat renal CYP4A2: arachidonic acid omega-hydroxylation and 11,12-epoxidation by CYP4A2 protein. | 1996 | Arch. Biochem. Biophys. | pmid:8954571 |
| Kinderlerer JL et al. | Effect of medium-chain fatty acids in mould ripened cheese on the growth of Listeria monocytogenes. | 1996 | J. Dairy Res. | pmid:8933308 |
| Kragh-Hansen U et al. | High-affinity binding of laurate to naturally occurring mutants of human serum albumin and proalbumin. | 1996 | Biochem. J. | pmid:9003380 |
| Powell PK et al. | Identification of CYP4A11 as the major lauric acid omega-hydroxylase in human liver microsomes. | 1996 | Arch. Biochem. Biophys. | pmid:8914854 |
| Vickers AE et al. | Hydroxyethyl cyclosporin A induces and decreases P4503A and P-glycoprotein levels in rat liver. | 1996 | Xenobiotica | pmid:8851819 |
| Petschow BW et al. | Susceptibility of Helicobacter pylori to bactericidal properties of medium-chain monoglycerides and free fatty acids. | 1996 | Antimicrob. Agents Chemother. | pmid:8834870 |
| Sherrington EJ et al. | Lack of effect of different dietary saturated fatty acids on adipose tissue deposition in the rat. | 1996 | Biochem. Soc. Trans. | pmid:8736816 |
| Maves SA et al. | Decreased substrate affinity upon alteration of the substrate-docking region in cytochrome P450(BM-3). | 1997 | FEBS Lett. | pmid:9315688 |
| Buhler DR et al. | The regiospecific hydroxylation of lauric acid by rainbow trout (Oncorhynchus mykiss) cytochrome P450s. | 1997 | Drug Metab. Dispos. | pmid:9321521 |
| Wiberg E et al. | Fatty acid distribution and lipid metabolism in developing seeds of laurate-producing rape (Brassica napus L.). | 1997 | Planta | pmid:9431681 |
| Kroetz DL et al. | Developmentally regulated expression of the CYP4A genes in the spontaneously hypertensive rat kidney. | 1997 | Mol. Pharmacol. | pmid:9281597 |
| Winkelaar GB et al. | Fat absorption after small intestinal transplantation in the rat. | 1997 | Transplantation | pmid:9293866 |
| Murataliev MB et al. | Functional interactions in cytochrome P450BM3: flavin semiquinone intermediates, role of NADP(H), and mechanism of electron transfer by the flavoprotein domain. | 1997 | Biochemistry | pmid:9204888 |
| Orellana M et al. | Microsomal and peroxisomal fatty acid oxidation in streptozotocin diabetic rat liver. | 1997 | Gen. Pharmacol. | pmid:9068973 |
| Amet Y et al. | Cytochrome P450 4A and 2E1 expression in human kidney microsomes. | 1997 | Biochem. Pharmacol. | pmid:9113097 |
| Khosla P et al. | Decreasing dietary lauric and myristic acids improves plasma lipids more favorably than decreasing dietary palmitic acid in rhesus monkeys fed AHA step 1 type diets. | 1997 | J. Nutr. | pmid:9082040 |
| Orellana M et al. | Microsomal and peroxisomal fatty acid oxidation in bile duct ligated rats: a comparative study between liver and kidney. | 1997 | Gen. Pharmacol. | pmid:9147020 |
| Clementz T et al. | Function of the Escherichia coli msbB gene, a multicopy suppressor of htrB knockouts, in the acylation of lipid A. Acylation by MsbB follows laurate incorporation by HtrB. | 1997 | J. Biol. Chem. | pmid:9099672 |
| Lu P et al. | Heme-coordinating analogs of lauric acid as inhibitors of fatty acid omega-hydroxylation. | 1997 | Arch. Biochem. Biophys. | pmid:8990261 |
| Winkler E et al. | Identification of the pH sensor for nucleotide binding in the uncoupling protein from brown adipose tissue. | 1997 | Biochemistry | pmid:8993328 |
| Helvig C et al. | Suicide inactivation of cytochrome P450 by midchain and terminal acetylenes. A mechanistic study of inactivation of a plant lauric acid omega-hydroxylase. | 1997 | J. Biol. Chem. | pmid:8995277 |
| Imaoka S et al. | Mutagenic activation of urinary bladder carcinogens by CYP4B1 and the presence of CYP4B1 in bladder mucosa. | 1997 | Biochem. Pharmacol. | pmid:9310344 |
| Crespi CL and Miller VP | The R144C change in the CYP2C9*2 allele alters interaction of the cytochrome P450 with NADPH:cytochrome P450 oxidoreductase. | 1997 | Pharmacogenetics | pmid:9241660 |
| Djelouah I et al. | Fat embolism in orthopedic surgery: role of bone marrow fatty acid. | 1997 | Anesth. Analg. | pmid:9249128 |
| Poli-Scaife S et al. | The substrate binding site of human liver cytochrome P450 2C9: an NMR study. | 1997 | Biochemistry | pmid:9335524 |
| Sunshine MG et al. | Mutation of the htrB gene in a virulent Salmonella typhimurium strain by intergeneric transduction: strain construction and phenotypic characterization. | 1997 | J. Bacteriol. | pmid:9287009 |
| Chevalier G et al. | Distribution study of radioactivity in rats after oral administration of the lipido/sterolic extract of Serenoa repens (Permixon) supplemented with [1-14C]-lauric acid, [1-14C]-oleic acid or [4-14C]-beta-sitosterol. | 1997 Jan-Mar | Eur J Drug Metab Pharmacokinet | pmid:9179563 |
| Sigalet DL et al. | Determination of the route of medium-chain and long-chain fatty acid absorption by direct measurement in the rat. | 1997 Sep-Oct | JPEN J Parenter Enteral Nutr | pmid:9323689 |
| Bardi L et al. | Esterase activity and release of ethyl esters of medium-chain fatty acids by Saccharomyces cerevisiae during anaerobic growth. | 1998 | Can. J. Microbiol. | pmid:10347863 |
| Lindmark T et al. | Absorption enhancement through intracellular regulation of tight junction permeability by medium chain fatty acids in Caco-2 cells. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9435199 |
| Crespi CL et al. | Determination of CYP4A11-catalyzed lauric acid 12-hydroxylation by high-performance liquid chromatography with radiometric detection. | 1998 | Methods Mol. Biol. | pmid:14577226 |
| Meyer JH et al. | Length of intestinal contact on nutrient-driven satiety. | 1998 | Am. J. Physiol. | pmid:9756564 |
| Guan X et al. | Cytochrome P450-dependent desaturation of lauric acid: isoform selectivity and mechanism of formation of 11-dodecenoic acid. | 1998 | Chem. Biol. Interact. | pmid:9566728 |
| Miura Y and Oda S | Oxidation of fatty acids by kidney microsomes of musk shrew (Suncus murinus). | 1998 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:9530812 |
| Amet Y et al. | P-450-dependent metabolism of lauric acid in alcoholic liver disease: comparison between rat liver and kidney microsomes. | 1998 | Alcohol. Clin. Exp. Res. | pmid:9581653 |
| Oszi Z and Pethö G | Quantitative determination of polysorbate 20 in nasal pharmaceutical preparations by high-performance liquid chromatography. | 1998 | J Pharm Biomed Anal | pmid:9919973 |
| Andersen Borge GI et al. | Fatty acid alpha-oxidation of tetradecylthioacetic acid and tetradecylthiopropionic acid in cucumber (Cucumis sativus). | 1998 | Biochim. Biophys. Acta | pmid:9795197 |
| Orellana M et al. | Peroxisomal and microsomal fatty acid oxidation in liver of rats after chronic ethanol consumption. | 1998 | Gen. Pharmacol. | pmid:9809485 |
| Kroetz DL et al. | Peroxisome proliferator-activated receptor alpha controls the hepatic CYP4A induction adaptive response to starvation and diabetes. | 1998 | J. Biol. Chem. | pmid:9813074 |
| Zheng YM et al. | Identification of a meander region proline residue critical for heme binding to cytochrome P450: implications for the catalytic function of human CYP4B1. | 1998 | Biochemistry | pmid:9737862 |
| Tappenden KA et al. | Short-chain fatty acid-supplemented total parenteral nutrition alters intestinal structure, glucose transporter 2 (GLUT2) mRNA and protein, and proglucagon mRNA abundance in normal rats. | 1998 | Am. J. Clin. Nutr. | pmid:9665105 |
| Lee Y et al. | Preparation of slightly hydrophobic heparin derivatives which can be used for solvent casting in polymeric formulation. | 1998 | Thromb. Res. | pmid:9840023 |
| Noble MA et al. | Imidazolyl carboxylic acids as mechanistic probes of flavocytochrome P-450 BM3. | 1998 | Biochemistry | pmid:9843385 |
| Orellana M et al. | Modulation of peroxisomal and microsomal fatty acid oxidation by acetone. A comparative study between liver and kidney. | 1998 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:9972312 |
| Amichot M et al. | Induction of cytochrome P450 activities in Drosophila melanogaster strains susceptible or resistant to insecticides. | 1998 | Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. | pmid:9972473 |