lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

Cross Reference

Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Lung Neoplasms D008175 171 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Acne Vulgaris D000152 35 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Thrombosis D013927 49 associated lipids
Prostatic Hyperplasia D011470 20 associated lipids
Brain Infarction D020520 17 associated lipids
Stroke D020521 32 associated lipids
Starvation D013217 47 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Seizures D012640 87 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Cerebral Infarction D002544 6 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Per page 10 20 50 | Total 33

PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

Download all related citations
Per page 10 20 50 100 | Total 1837
Authors Title Published Journal PubMed Link
Cunha MT et al. Effect of salts and surfactants on the partitioning of Fusarium solani pisi cutinase in aqueous two-phase systems of thermoseparating ethylene oxide/propylene oxide random copolymer and hydroxypropyl starch. 2000 Bioseparation pmid:11321518
Lu Y et al. Impedance spectroscopy analysis of human odorant binding proteins immobilized on nanopore arrays for biochemical detection. 2016 Biosens Bioelectron pmid:26710343
Wojciechowski K and Buffle J The interaction of azacrown ether with fatty acid in nonpolar solvents and at the organic-aqueous interface. 2004 Biosens Bioelectron pmid:15556348
Tamaki K et al. Cloning, expression in yeast, and functional characterization of CYP76A4, a novel cytochrome P450 of petunia that catalyzes (omega-1)-hydroxylation of lauric acid. 2005 Biosci. Biotechnol. Biochem. pmid:15725669
Oba Y et al. Enzymatic and genetic characterization of firefly luciferase and Drosophila CG6178 as a fatty acyl-CoA synthetase. 2005 Biosci. Biotechnol. Biochem. pmid:15849423
Imaishi H and Petkova-Andonova M Molecular cloning of CYP76B9, a cytochrome P450 from Petunia hybrida, catalyzing the omega-hydroxylation of capric acid and lauric acid. 2007 Biosci. Biotechnol. Biochem. pmid:17213671
Imaishi H et al. Encoding of a cytochrome P450-dependent lauric acid monooxygenase by CYP703A1 specifically expressed in the floral buds of petunia hybrida. 1999 Biosci. Biotechnol. Biochem. pmid:10664841
Imaishi H et al. CYP78A1 preferentially expressed in developing inflorescences of Zea mays encoded a cytochrome P450-dependent lauric acid 12-monooxygenase. 2000 Biosci. Biotechnol. Biochem. pmid:10993158
Petkova-Andonova M et al. CYP92B1, A cytochrome P450, expressed in petunia flower buds, that catalyzes monooxidation of long-chain fatty acids. 2002 Biosci. Biotechnol. Biochem. pmid:12400678
Sun J et al. Production of P(3-hydroxybutyrate-co-3-hydroxyhexanoate-co-3-hydroxyoctanoate) terpolymers using a chimeric PHA synthase in recombinant Ralstonia eutropha and Pseudomonas putida. 2010 Biosci. Biotechnol. Biochem. pmid:20699558
Okino N et al. Expression, purification, and characterization of a recombinant neutral ceramidase from Mycobacterium tuberculosis. 2010 Biosci. Biotechnol. Biochem. pmid:20139604
Kato D et al. Comparison of acyl-CoA synthetic activities and enantioselectivity toward 2-arylpropanoic acids in firefly luciferases. 2011 Biosci. Biotechnol. Biochem. pmid:21897032
Sugihara A et al. Purification and characterization of a novel cholesterol esterase from Pseudomonas aeruginosa, with its application to cleaning lipid-stained contact lenses. 2002 Biosci. Biotechnol. Biochem. pmid:12506971
Bora PS et al. Characterization of principal nutritional components of Brazilian oil palm (Eliaes guineensis) fruits. 2003 Bioresour. Technol. pmid:12733568
Huang Z et al. Direct production of cellulose laurate by mechanical activation-strengthened solid phase synthesis. 2012 Bioresour. Technol. pmid:22683327
Chen SY et al. Production of Jatropha biodiesel fuel over sulfonic acid-based solid acids. 2014 Bioresour. Technol. pmid:24548779
Gremos S et al. Supercritical carbon dioxide biocatalysis as a novel and green methodology for the enzymatic acylation of fibrous cellulose in one step. 2012 Bioresour. Technol. pmid:22014705
Wang T et al. Mechanical properties of polyurethane foams prepared from liquefied corn stover with PAPI. 2008 Bioresour. Technol. pmid:17604162
Liu F et al. Metabolic engineering of Aeromonas hydrophila 4AK4 for production of copolymers of 3-hydroxybutyrate and medium-chain-length 3-hydroxyalkanoate. 2011 Bioresour. Technol. pmid:21680176
Bozic AK et al. Effects of the methane-inhibitors nitrate, nitroethane, lauric acid, Lauricidin and the Hawaiian marine algae Chaetoceros on ruminal fermentation in vitro. 2009 Bioresour. Technol. pmid:19362827
Gremos S et al. Direct enzymatic acylation of cellulose pretreated in BMIMCl ionic liquid. 2011 Bioresour. Technol. pmid:20888759
Serri NA et al. Studies of reaction parameters on synthesis of Citronellyl laurate ester via immobilized Candida rugosa lipase in organic media. 2006 Bioprocess Biosyst Eng pmid:16868763
Zeng C et al. Enzymatic synthesis of phytosterol esters catalyzed by Candida rugosa lipase in water-in-[Bmim]PF6 microemulsion. 2015 Bioprocess Biosyst Eng pmid:25575761
Rahman NK et al. Enzymatic synthesis of farnesyl laurate in organic solvent: initial water activity, kinetics mechanism, optimization of continuous operation using packed bed reactor and mass transfer studies. 2011 Bioprocess Biosyst Eng pmid:21327986
Rajan A and Abraham TE Enzymatic modification of cassava starch by bacterial lipase. 2006 Bioprocess Biosyst Eng pmid:16736230
Bello M and García-Hernández E Ligand entry into the calyx of β-lactoglobulin. 2014 Biopolymers pmid:24865819
Doktycz MJ et al. Studies of DNA dumbbells. IV. Preparation and melting of a DNA dumbbell with the 16 base-pair sequence 5'G-T-A-T-C-C-C-T-C-T-G-G-A-T-A-C3' linked on the ends by dodecyl chains. 1993 Biopolymers pmid:8268405
Zhou X et al. Structural characterization of myotoxic ecarpholin S from Echis carinatus venom. 2008 Biophys. J. pmid:18586854
Ueda I and Suzuki A Is there a specific receptor for anesthetics? Contrary effects of alcohols and fatty acids on phase transition and bioluminescence of firefly luciferase. 1998 Biophys. J. pmid:9675206
Macdonald ID et al. Fatty acid-induced alteration of the porphyrin macrocycle of cytochrome P450 BM3. 1998 Biophys. J. pmid:9635777
Kragh-Hansen U et al. Detergents as probes of hydrophobic binding cavities in serum albumin and other water-soluble proteins. 2001 Biophys. J. pmid:11371462
Rocha S et al. Influence of fluorinated and hydrogenated nanoparticles on the structure and fibrillogenesis of amyloid beta-peptide. 2008 Biophys. Chem. pmid:18625543
Bello M et al. Structure and dynamics of β-lactoglobulin in complex with dodecyl sulfate and laurate: a molecular dynamics study. 2012 Biophys. Chem. pmid:22498503
Hall M et al. Interaction of dexloxiglumide, a cholecystokinin type-1 receptor antagonist, with human cytochromes P450. 2004 Biopharm Drug Dispos pmid:15108219
Lorenz C et al. Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cells. 2004 Bioorg. Med. Chem. Lett. pmid:15341962
Krouit M et al. New photoantimicrobial films composed of porphyrinated lipophilic cellulose esters. 2006 Bioorg. Med. Chem. Lett. pmid:16377183
Agarwal HK et al. Synthesis and anti-HIV activities of symmetrical dicarboxylate esters of dinucleoside reverse transcriptase inhibitors. 2012 Bioorg. Med. Chem. Lett. pmid:22858097
Koda Y et al. Synthesis and in vitro evaluation of a library of modified endomorphin 1 peptides. 2008 Bioorg. Med. Chem. pmid:18468445
Pavlova IuB et al. [Synthesis of photoreactive diglyceride--a protein kinase C ligand]. 1994 Bioorg. Khim. pmid:7945463
Axarli I et al. Engineering the substrate specificity of cytochrome P450 CYP102A2 by directed evolution: production of an efficient enzyme for bioconversion of fine chemicals. 2005 Biomol. Eng. pmid:15857787
Morais PC et al. Raman spectroscopy in magnetic fluids. 2001 Biomol. Eng. pmid:11163750
Dong GC et al. Preparation and characterization of surface-modified calcium hydrogenphosphate by hexamethylene diisocyanates. 2000 Biomed Sci Instrum pmid:10834217
de Mel A et al. In situ endothelialization potential of a biofunctionalised nanocomposite biomaterial-based small diameter bypass graft. 2009 Biomed Mater Eng pmid:20042799
Lodhia J et al. Development and use of iron oxide nanoparticles (Part 1): Synthesis of iron oxide nanoparticles for MRI. 2010 Apr-Jun Biomed Imaging Interv J pmid:21611034
Kudriavtsev V et al. Heart energy signature spectrogram for cardiovascular diagnosis. 2007 Biomed Eng Online pmid:17480232
Yang J et al. The biocompatibility of fatty acid modified dextran-agmatine bioconjugate gene delivery vector. 2012 Biomaterials pmid:21996530
Yang D et al. The antimicrobial activity of liposomal lauric acids against Propionibacterium acnes. 2009 Biomaterials pmid:19665786
Wu EC et al. Real-time monitoring of sustained drug release using the optical properties of porous silicon photonic crystal particles. 2011 Biomaterials pmid:21122914
Renouf-Glauser AC et al. A degradation study of PLLA containing lauric acid. 2005 Biomaterials pmid:15585245
Renouf-Glauser AC et al. Comparison of the hydrolytic degradation and deformation properties of a PLLA-lauric acid based family of biomaterials. 2006 Biomacromolecules pmid:16471938
Lapitsky Y et al. Modular biodegradable biomaterials from surfactant and polyelectrolyte mixtures. 2008 Biomacromolecules pmid:18088095
Xu L et al. Transfection efficiency of DNA enhanced by association with salt-free catanionic vesicles. 2013 Biomacromolecules pmid:23865722
Li YY et al. Novel stimuli-responsive micelle self-assembled from Y-shaped P(UA-Y-NIPAAm) copolymer for drug delivery. 2006 Biomacromolecules pmid:17096519
Matsumoto K et al. Synergistic effects of Glu130Asp substitution in the type II polyhydroxyalkanoate (PHA) synthase: enhancement of PHA production and alteration of polymer molecular weight. Biomacromolecules pmid:15638509
Kwok CS et al. Surface modification of polymers with self-assembled molecular structures: multitechnique surface characterization. 2000 Biomacromolecules pmid:11709836
Ouyang SP et al. Production of polyhydroxyalkanoates with high 3-hydroxydodecanoate monomer content by fadB and fadA knockout mutant of Pseudomonas putida KT2442. 2007 Biomacromolecules pmid:17661516
Park SJ et al. Production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) by metabolically engineered Escherichia coli strains. 2001 Biomacromolecules pmid:11749180
Lyngby J et al. Quantification of lipopolysaccharides in outer membrane vesicle vaccines against meningococcal disease. High-performance liquid chromatographic determination of the constituent 3-hydroxy-lauric acid. 2002 Biologicals pmid:11846425
Fichorova RN et al. Interleukin (IL)-1, IL-6, and IL-8 predict mucosal toxicity of vaginal microbicidal contraceptives. 2004 Biol. Reprod. pmid:15128598
Hiratsuka M et al. Effects of gonadectomy and sex hormones on the induction of hepatic CYP4A by clofibrate in rats. 1996 Biol. Pharm. Bull. pmid:8820907
Miyake M et al. Optimization of suppository preparation containing sodium laurate and taurine that can safely improve rectal absorption of rebamipide. 2006 Biol. Pharm. Bull. pmid:16462041
Ogiso T et al. Percutaneous penetration of ozagrel and the enhancement produced by saturated fatty acids. 2000 Biol. Pharm. Bull. pmid:10919364
Komata Y et al. Accumulation of lauric acid in skin as an enhancer for the percutaneous absorption of thiamine disulfide. 1995 Biol. Pharm. Bull. pmid:7493004
Kitahara T et al. Antimicrobial activity of saturated fatty acids and fatty amines against methicillin-resistant Staphylococcus aureus. 2004 Biol. Pharm. Bull. pmid:15340213
Hiratsuka M et al. Sex differences in constitutive level of renal lauric acid hydroxylase activities and CYP4A-related proteins in mice. 1996 Biol. Pharm. Bull. pmid:8860949
Lee CK et al. Relationship between lipophilicity and skin permeability of various drugs from an ethanol/water/lauric acid system. 1994 Biol. Pharm. Bull. pmid:7874070
Komata Y et al. Effect of fatty acid on the accumulation of thiamine disulfide in rat skin. 1994 Biol. Pharm. Bull. pmid:7920438
Miwa T et al. Modulation of morphine action by lauric acid. 1993 Biol. Pharm. Bull. pmid:8220329
Abe M et al. Pharmacologically relevant receptor binding characteristics and 5alpha-reductase inhibitory activity of free Fatty acids contained in saw palmetto extract. 2009 Biol. Pharm. Bull. pmid:19336899
Lee CK et al. Transdermal delivery of theophylline using an ethanol/panasate 800-ethylcellulose gel preparation. 1995 Biol. Pharm. Bull. pmid:7735237
Demarne Y et al. Effects of maternal dodecanoic or lauric acid (C12:0) feeding on milk fatty acid secretion and lipogenesis in the suckling rat. 1977 Biol. Neonate pmid:610766
Zöllner A et al. Human CYP4Z1 catalyzes the in-chain hydroxylation of lauric acid and myristic acid. 2009 Biol. Chem. pmid:19090726
Andreiuk GM and Kiselev PA [Initiation of lipid peroxidation as a result of hemoglobin transformation into hemichrome induced by free fatty acids]. 1988 Biokhimiia pmid:3179347
Kundu S and Roy D Structural study of biologically significant ligands with major birch pollen allergen Betv1 by docking and molecular dynamics simulation. 2010 Bioinformation pmid:20978606
Bhore SJ and Shah FH Construction of efficient and effective transformation vectors for palmitoyl-acyl carrier protein thioesterase gene silencing in oil palm. 2011 Bioinformation pmid:21738318
Kumar S Comparative modeling and molecular docking of orphan human CYP4V2 protein with fatty acid substrates: Insights into substrate specificity. 2011 Bioinformation pmid:22355237
Nicol JW et al. The Integrated Genome Browser: free software for distribution and exploration of genome-scale datasets. 2009 Bioinformatics pmid:19654113
Obraztsov VV et al. [Rate of interaction of ferricytochrome c with negatively charged liposomes from natural lecithin: effect of the physicochemical state of the membrane hydrophobic layer]. 1975 Nov-Dec Biofizika pmid:173407
Selishcheva AA et al. [Influence of phospholipids of different natures on the structure of ferricytochrome c]. 1977 Jul-Aug Biofizika pmid:198019
Orlov SN et al. [Fluorescence analysis study of the lability of biomembranes and their components. III. Kinetics of complex formation between bovine serum albumin molecules and higher saturated fatty acids]. 1976 Jan-Feb Biofizika pmid:1252538
Preobrazhenskaia TA et al. [Comparative effect of polymyxin B on lipid bilayer membranes with different lipid composition]. 1994 Nov-Dec Biofizika pmid:7873621
Huo Q et al. Molecular modification of proanthocyanidins. 2016 Bioengineered pmid:27459598
van Ginkel CG et al. Substrate specificity of a long-chain alkylamine-degrading Pseudomonas sp isolated from activated sludge. 2008 Biodegradation pmid:17492358
Chu-Kung AF et al. Promotion of peptide antimicrobial activity by fatty acid conjugation. Bioconjug. Chem. pmid:15149180
Magata Y et al. A Tc-99m-labeled long chain fatty acid derivative for myocardial imaging. Bioconjug. Chem. pmid:15025536
Larsson A and Erlanson-Albertsson C Effect of phosphatidylcholine and free fatty acids on the activity of pancreatic lipase-colipase. 1986 Biochim. Biophys. Acta pmid:3707983
Sawamura A et al. Catalytic properties of rabbit kidney fatty acid omega-hydroxylase cytochrome P-450ka2 (CYP4A7). 1993 Biochim. Biophys. Acta pmid:8504139
Dlasková A et al. Certain aspects of uncoupling due to mitochondrial uncoupling proteins in vitro and in vivo. 2006 May-Jun Biochim. Biophys. Acta pmid:16781660
Simonyan RA et al. Cold-induced changes in the energy coupling and the UCP3 level in rodent skeletal muscles. 2001 Biochim. Biophys. Acta pmid:11334791
Ichihara K et al. Some properties of the fatty alcohol oxidation system and reconstitution of microsomal oxidation activity in intestinal mucosa. 1986 Biochim. Biophys. Acta pmid:3530336
Hibbs AR and Marzuki S An assessment of the ability of yeast cells to incorporate photolabile fatty acids into their membrane phospholipids in vivo. 1986 Biochim. Biophys. Acta pmid:3535894
Nilsson A et al. Studies on the interrelated stimulation of microsomal omega-oxidation and peroxisomal beta-oxidation in rat liver with a partially hydrogenated fish oil diet. 1987 Biochim. Biophys. Acta pmid:3607073
Nielsen AD et al. Thermochemistry of the specific binding of C12 surfactants to bovine serum albumin. 2000 Biochim. Biophys. Acta pmid:11004550
Chua MM et al. Attachment of immunoglobulin to liposomal membrane via protein carbohydrate. 1984 Biochim. Biophys. Acta pmid:6432057
Lehmler HJ and Bummer PM Mixing of perfluorinated carboxylic acids with dipalmitoylphosphatidylcholine. 2004 Biochim. Biophys. Acta pmid:15328046
McDonough V et al. Mutations in erg4 affect the sensitivity of Saccharomyces cerevisiae to medium-chain fatty acids. 2002 Biochim. Biophys. Acta pmid:12020638
Chiswell B et al. Structural features of the ligand binding site on human complement protein C8gamma: a member of the lipocalin family. 2007 Biochim. Biophys. Acta pmid:17452033
Kitajima Y and Thompson GA Self-regulation of membrane fluidity. The effect of saturated normal and methoxy fatty acid supplementation on Tetrahymena membrane physical properties and lipid composition. 1977 Biochim. Biophys. Acta pmid:406916
Gumpen S et al. Thermal stability of fatty acid-serum albumin complexes studied by differential scanning calorimetry. 1979 Biochim. Biophys. Acta pmid:486509
Mabrey S and Sturtevant JM Incorporation of saturated fatty acids into phosphatidylcholine bilayers. 1977 Biochim. Biophys. Acta pmid:856286