| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Prostatic Hyperplasia | D011470 | 20 associated lipids |
| Brain Infarction | D020520 | 17 associated lipids |
| Stroke | D020521 | 32 associated lipids |
| Starvation | D013217 | 47 associated lipids |
| Leukemia, Myeloid | D007951 | 52 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Cerebrovascular Disorders | D002561 | 25 associated lipids |
| Cerebral Infarction | D002544 | 6 associated lipids |
| Liver Diseases, Alcoholic | D008108 | 13 associated lipids |
lauric acid
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
Cross Reference
Introduction
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with lauric acid?
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Am. J. Clin. Nutr. (1)
- Am. J. Physiol. Heart Circ. Physiol. (1)
- Antimicrob. Agents Chemother. (1)
- Others (7)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with lauric acid
PubChem Associated disorders and diseases
What pathways are associated with lauric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with lauric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with lauric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with lauric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with lauric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with lauric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with lauric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kolattukudy PE and Rogers L | Biosynthesis of 3-hydroxy fatty acids, the pheromone components of female mallard ducks, by cell-free preparations from the uropygial gland. | 1987 | Arch. Biochem. Biophys. | pmid:3813530 |
| Shet Ms et al. | The omega-hydroxlyation of lauric acid: oxidation of 12-hydroxlauric acid to dodecanedioic acid by a purified recombinant fusion protein containing P450 4A1 and NADPH-P450 reductase. | 1996 | Arch. Biochem. Biophys. | pmid:8651697 |
| Brodersen R et al. | Cobinding of bilirubin and sulfonamide and of two bilirubin molecules to human serum albumin: a site model. | 1987 | Arch. Biochem. Biophys. | pmid:3813550 |
| Lewis DF | Essential requirements for substrate binding affinity and selectivity toward human CYP2 family enzymes. | 2003 | Arch. Biochem. Biophys. | pmid:12464242 |
| Puchkaev AV et al. | Aromatic stacking as a determinant of the thermal stability of CYP119 from Sulfolobus solfataricus. | 2003 | Arch. Biochem. Biophys. | pmid:12464244 |
| Finlayson MJ et al. | Differential expression of cytochrome P-450 1 and related forms in rabbit liver and kidney. | 1987 | Arch. Biochem. Biophys. | pmid:3492962 |
| Capdevila J et al. | Influence of a fibric acid type of hypolipidemic agent on the oxidative metabolism of arachidonic acid by liver microsomal cytochrome P-450. | 1985 | Arch. Biochem. Biophys. | pmid:3933431 |
| Norman HA and Thompson GA | Effects of low-temperature stress on the metabolism of phosphatidylglycerol molecular species in Dunaliella salina. | 1985 | Arch. Biochem. Biophys. | pmid:4051499 |
| Arkill KP and Winlove CP | Fatty acid transport in articular cartilage. | 2006 | Arch. Biochem. Biophys. | pmid:17084376 |
| Powell PK et al. | Identification of CYP4A11 as the major lauric acid omega-hydroxylase in human liver microsomes. | 1996 | Arch. Biochem. Biophys. | pmid:8914854 |
| Lu P et al. | Heme-coordinating analogs of lauric acid as inhibitors of fatty acid omega-hydroxylation. | 1997 | Arch. Biochem. Biophys. | pmid:8990261 |
| Jeffery B et al. | Peroxisome proliferator activated receptor alpha regulates a male-specific cytochrome P450 in mouse liver. | 2004 | Arch. Biochem. Biophys. | pmid:15313227 |
| Chaurasia CS et al. | Biochemical characterization of lauric acid omega-hydroxylation by a CYP4A1/NADPH-cytochrome P450 reductase fusion protein. | 1995 | Arch. Biochem. Biophys. | pmid:7872779 |
| Cowart LA et al. | Structural determinants of active site binding affinity and metabolism by cytochrome P450 BM-3. | 2001 | Arch. Biochem. Biophys. | pmid:11368173 |
| Duncan T et al. | A glycoprotein binding retinoids and fatty acids is present in Drosophila. | 1994 | Arch. Biochem. Biophys. | pmid:8031123 |
| Gilep AA et al. | Reconstitution of the enzymatic activities of cytochrome P450s using recombinant flavocytochromes containing rat cytochrome b(5) fused to NADPH--cytochrome P450 reductase with various membrane-binding segments. | 2001 | Arch. Biochem. Biophys. | pmid:11396924 |
| Sato H et al. | Multiple binding of bilirubin to human serum albumin and cobinding with laurate. | 1988 | Arch. Biochem. Biophys. | pmid:2829743 |
| Kikuta Y et al. | Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14. | 2000 | Arch. Biochem. Biophys. | pmid:11185557 |
| Straub P et al. | Hydrophobic side chain requirements for lauric acid and progesterone hydroxylation at amino acid 113 in cytochrome P450 2C2, a potential determinant of substrate specificity. | 1993 | Arch. Biochem. Biophys. | pmid:8215458 |
| Chavez JA and Summers SA | Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes. | 2003 | Arch. Biochem. Biophys. | pmid:14592453 |