lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with lauric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Ramsey BL and Westphal U | Steroid-protein interactions. 40. The effect of fatty acids on progesterone binding to human serum albumin. | 1978 | Biochim. Biophys. Acta | pmid:638175 |
Popov VN et al. | Effects of cold exposure in vivo and uncouplers and recouplers in vitro on potato tuber mitochondria. | 2002 | Biochim. Biophys. Acta | pmid:11997132 |
Chu-Kung AF et al. | Promotion of peptide antimicrobial activity by fatty acid conjugation. | Bioconjug. Chem. | pmid:15149180 | |
Magata Y et al. | A Tc-99m-labeled long chain fatty acid derivative for myocardial imaging. | Bioconjug. Chem. | pmid:15025536 | |
van Ginkel CG et al. | Substrate specificity of a long-chain alkylamine-degrading Pseudomonas sp isolated from activated sludge. | 2008 | Biodegradation | pmid:17492358 |
Huo Q et al. | Molecular modification of proanthocyanidins. | 2016 | Bioengineered | pmid:27459598 |
Obraztsov VV et al. | [Rate of interaction of ferricytochrome c with negatively charged liposomes from natural lecithin: effect of the physicochemical state of the membrane hydrophobic layer]. | 1975 Nov-Dec | Biofizika | pmid:173407 |
Selishcheva AA et al. | [Influence of phospholipids of different natures on the structure of ferricytochrome c]. | 1977 Jul-Aug | Biofizika | pmid:198019 |
Orlov SN et al. | [Fluorescence analysis study of the lability of biomembranes and their components. III. Kinetics of complex formation between bovine serum albumin molecules and higher saturated fatty acids]. | 1976 Jan-Feb | Biofizika | pmid:1252538 |
Preobrazhenskaia TA et al. | [Comparative effect of polymyxin B on lipid bilayer membranes with different lipid composition]. | 1994 Nov-Dec | Biofizika | pmid:7873621 |
Nicol JW et al. | The Integrated Genome Browser: free software for distribution and exploration of genome-scale datasets. | 2009 | Bioinformatics | pmid:19654113 |
Kundu S and Roy D | Structural study of biologically significant ligands with major birch pollen allergen Betv1 by docking and molecular dynamics simulation. | 2010 | Bioinformation | pmid:20978606 |
Bhore SJ and Shah FH | Construction of efficient and effective transformation vectors for palmitoyl-acyl carrier protein thioesterase gene silencing in oil palm. | 2011 | Bioinformation | pmid:21738318 |
Kumar S | Comparative modeling and molecular docking of orphan human CYP4V2 protein with fatty acid substrates: Insights into substrate specificity. | 2011 | Bioinformation | pmid:22355237 |
Andreiuk GM and Kiselev PA | [Initiation of lipid peroxidation as a result of hemoglobin transformation into hemichrome induced by free fatty acids]. | 1988 | Biokhimiia | pmid:3179347 |
Zöllner A et al. | Human CYP4Z1 catalyzes the in-chain hydroxylation of lauric acid and myristic acid. | 2009 | Biol. Chem. | pmid:19090726 |
Demarne Y et al. | Effects of maternal dodecanoic or lauric acid (C12:0) feeding on milk fatty acid secretion and lipogenesis in the suckling rat. | 1977 | Biol. Neonate | pmid:610766 |
Hiratsuka M et al. | Effects of gonadectomy and sex hormones on the induction of hepatic CYP4A by clofibrate in rats. | 1996 | Biol. Pharm. Bull. | pmid:8820907 |
Miyake M et al. | Optimization of suppository preparation containing sodium laurate and taurine that can safely improve rectal absorption of rebamipide. | 2006 | Biol. Pharm. Bull. | pmid:16462041 |
Ogiso T et al. | Percutaneous penetration of ozagrel and the enhancement produced by saturated fatty acids. | 2000 | Biol. Pharm. Bull. | pmid:10919364 |
Komata Y et al. | Accumulation of lauric acid in skin as an enhancer for the percutaneous absorption of thiamine disulfide. | 1995 | Biol. Pharm. Bull. | pmid:7493004 |
Kitahara T et al. | Antimicrobial activity of saturated fatty acids and fatty amines against methicillin-resistant Staphylococcus aureus. | 2004 | Biol. Pharm. Bull. | pmid:15340213 |
Hiratsuka M et al. | Sex differences in constitutive level of renal lauric acid hydroxylase activities and CYP4A-related proteins in mice. | 1996 | Biol. Pharm. Bull. | pmid:8860949 |
Lee CK et al. | Relationship between lipophilicity and skin permeability of various drugs from an ethanol/water/lauric acid system. | 1994 | Biol. Pharm. Bull. | pmid:7874070 |
Komata Y et al. | Effect of fatty acid on the accumulation of thiamine disulfide in rat skin. | 1994 | Biol. Pharm. Bull. | pmid:7920438 |
Miwa T et al. | Modulation of morphine action by lauric acid. | 1993 | Biol. Pharm. Bull. | pmid:8220329 |
Abe M et al. | Pharmacologically relevant receptor binding characteristics and 5alpha-reductase inhibitory activity of free Fatty acids contained in saw palmetto extract. | 2009 | Biol. Pharm. Bull. | pmid:19336899 |
Lee CK et al. | Transdermal delivery of theophylline using an ethanol/panasate 800-ethylcellulose gel preparation. | 1995 | Biol. Pharm. Bull. | pmid:7735237 |
Fichorova RN et al. | Interleukin (IL)-1, IL-6, and IL-8 predict mucosal toxicity of vaginal microbicidal contraceptives. | 2004 | Biol. Reprod. | pmid:15128598 |
Lyngby J et al. | Quantification of lipopolysaccharides in outer membrane vesicle vaccines against meningococcal disease. High-performance liquid chromatographic determination of the constituent 3-hydroxy-lauric acid. | 2002 | Biologicals | pmid:11846425 |
Renouf-Glauser AC et al. | Comparison of the hydrolytic degradation and deformation properties of a PLLA-lauric acid based family of biomaterials. | 2006 | Biomacromolecules | pmid:16471938 |
Lapitsky Y et al. | Modular biodegradable biomaterials from surfactant and polyelectrolyte mixtures. | 2008 | Biomacromolecules | pmid:18088095 |
Xu L et al. | Transfection efficiency of DNA enhanced by association with salt-free catanionic vesicles. | 2013 | Biomacromolecules | pmid:23865722 |
Li YY et al. | Novel stimuli-responsive micelle self-assembled from Y-shaped P(UA-Y-NIPAAm) copolymer for drug delivery. | 2006 | Biomacromolecules | pmid:17096519 |
Matsumoto K et al. | Synergistic effects of Glu130Asp substitution in the type II polyhydroxyalkanoate (PHA) synthase: enhancement of PHA production and alteration of polymer molecular weight. | Biomacromolecules | pmid:15638509 | |
Kwok CS et al. | Surface modification of polymers with self-assembled molecular structures: multitechnique surface characterization. | 2000 | Biomacromolecules | pmid:11709836 |
Ouyang SP et al. | Production of polyhydroxyalkanoates with high 3-hydroxydodecanoate monomer content by fadB and fadA knockout mutant of Pseudomonas putida KT2442. | 2007 | Biomacromolecules | pmid:17661516 |
Park SJ et al. | Production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) by metabolically engineered Escherichia coli strains. | 2001 | Biomacromolecules | pmid:11749180 |
Yang J et al. | The biocompatibility of fatty acid modified dextran-agmatine bioconjugate gene delivery vector. | 2012 | Biomaterials | pmid:21996530 |
Yang D et al. | The antimicrobial activity of liposomal lauric acids against Propionibacterium acnes. | 2009 | Biomaterials | pmid:19665786 |
Wu EC et al. | Real-time monitoring of sustained drug release using the optical properties of porous silicon photonic crystal particles. | 2011 | Biomaterials | pmid:21122914 |
Renouf-Glauser AC et al. | A degradation study of PLLA containing lauric acid. | 2005 | Biomaterials | pmid:15585245 |
Kudriavtsev V et al. | Heart energy signature spectrogram for cardiovascular diagnosis. | 2007 | Biomed Eng Online | pmid:17480232 |
Lodhia J et al. | Development and use of iron oxide nanoparticles (Part 1): Synthesis of iron oxide nanoparticles for MRI. | 2010 Apr-Jun | Biomed Imaging Interv J | pmid:21611034 |
de Mel A et al. | In situ endothelialization potential of a biofunctionalised nanocomposite biomaterial-based small diameter bypass graft. | 2009 | Biomed Mater Eng | pmid:20042799 |
Dong GC et al. | Preparation and characterization of surface-modified calcium hydrogenphosphate by hexamethylene diisocyanates. | 2000 | Biomed Sci Instrum | pmid:10834217 |
Axarli I et al. | Engineering the substrate specificity of cytochrome P450 CYP102A2 by directed evolution: production of an efficient enzyme for bioconversion of fine chemicals. | 2005 | Biomol. Eng. | pmid:15857787 |
Morais PC et al. | Raman spectroscopy in magnetic fluids. | 2001 | Biomol. Eng. | pmid:11163750 |
Pavlova IuB et al. | [Synthesis of photoreactive diglyceride--a protein kinase C ligand]. | 1994 | Bioorg. Khim. | pmid:7945463 |
Koda Y et al. | Synthesis and in vitro evaluation of a library of modified endomorphin 1 peptides. | 2008 | Bioorg. Med. Chem. | pmid:18468445 |