lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with lauric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Idris CA and Sundram K | Effect of dietary cholesterol, trans and saturated fatty acids on serum lipoproteins in non-human primates. | 2002 | Asia Pac J Clin Nutr | pmid:12492627 |
Serra I et al. | Effect of dietary intake on the levels of biliary unsaturated free Fatty acids having inhibitory activity on mutagens. | 2009 | Asian Pac. J. Cancer Prev. | pmid:20104986 |
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Arrol S et al. | The effects of fatty acids on apolipoprotein B secretion by human hepatoma cells (HEP G2). | 2000 | Atherosclerosis | pmid:10856517 |
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Lagrost L et al. | Variations in serum cholesteryl ester transfer and phospholipid transfer activities in healthy women and men consuming diets enriched in lauric, palmitic or oleic acids. | 1999 | Atherosclerosis | pmid:10030391 |
Timbermont L et al. | Control of Clostridium perfringens-induced necrotic enteritis in broilers by target-released butyric acid, fatty acids and essential oils. | 2010 | Avian Pathol. | pmid:20390546 |
Alves NF et al. | Acute Treatment with Lauric Acid Reduces Blood Pressure and Oxidative Stress in Spontaneously Hypertensive Rats. | 2017 | Basic Clin. Pharmacol. Toxicol. | pmid:28054477 |
Stark K et al. | Expression of CYP4F12 in gastrointestinal and urogenital epithelia. | 2004 | Basic Clin. Pharmacol. Toxicol. | pmid:15078342 |
Russell VA et al. | Animal models of attention-deficit hyperactivity disorder. | 2005 | Behav Brain Funct | pmid:16022733 |
Hu H et al. | A novel class of antagonists for the FFAs receptor GPR40. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19818732 |
Imaoka S et al. | Induction of renal cytochrome P-450 in hepatic microsomes of diabetic rats. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3365247 |
Alterman MA et al. | Heteroatom substitution shifts regioselectivity of lauric acid metabolism from omega-hydroxylation to (omega-1)-oxidation. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7575514 |
Kiffel L et al. | Purification and characterization of a cytochrome P-450 isozyme isolated from the liver of rats pretreated with clofibrate. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3140811 |
Björkhem I and Hamberg M | On the rate-limiting step in W-hydroxylation of lauric acid. | 1972 | Biochem. Biophys. Res. Commun. | pmid:4662395 |
Amet Y et al. | Evidence that cytochrome P450 2E1 is involved in the (omega-1)-hydroxylation of lauric acid in rat liver microsomes. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8093035 |
Tanaka T et al. | Saturated and trans-unsaturated fatty acids elicit high levels of superoxide generation in intact and cell-free preparations of neutrophils. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3034258 |