lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with lauric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kubo I et al. | Naturally occurring antiacne agents. | 1994 | J. Nat. Prod. | pmid:8158169 |
Preobrazhenskaia TA et al. | [Comparative effect of polymyxin B on lipid bilayer membranes with different lipid composition]. | 1994 Nov-Dec | Biofizika | pmid:7873621 |
Clarke SE et al. | Lauric acid as a model substrate for the simultaneous determination of cytochrome P450 2E1 and 4A in hepatic microsomes. | 1994 Nov-Dec | Chem. Res. Toxicol. | pmid:7696540 |
Motoyama Y et al. | Effect of TFC-612, a 7-thia prostaglandin E1 derivative, on a peripheral arterial occlusive disease model in rats. | 1995 | Prostaglandins | pmid:7652186 |
Smith SW and Anderson BD | Human skin permeability enhancement by lauric acid under equilibrium aqueous conditions. | 1995 | J Pharm Sci | pmid:7658343 |
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Castle PJ et al. | Human liver lauric acid hydroxylase activities. | 1995 | Drug Metab. Dispos. | pmid:8654190 |
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Niederprüm HJ et al. | Inhibition of steroid 5 alpha-reductase activity by aliphatic fatty acids. Candidates for chemoprevention of prostate cancer. | 1995 | Ann. N. Y. Acad. Sci. | pmid:8526353 |
Lee SK et al. | Defective glucose-stimulated insulin release from perifused islets of C57BL/6J mice. | 1995 | Pancreas | pmid:7479681 |
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Modi S et al. | NMR studies of substrate binding to cytochrome P450 BM3: comparisons to cytochrome P450 cam. | 1995 | Biochemistry | pmid:7619797 |
Alterman MA et al. | Heteroatom substitution shifts regioselectivity of lauric acid metabolism from omega-hydroxylation to (omega-1)-oxidation. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7575514 |
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Iwami Y et al. | Effect of sucrose monolaurate on acid production, levels of glycolytic intermediates, and enzyme activities of Streptococcus mutans NCTC 10449. | 1995 | J. Dent. Res. | pmid:7560425 |
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Takahashi N et al. | Inhibition of in vitro aflatoxin B1-DNA binding in rainbow trout by CYP1A inhibitors: alpha-naphthoflavone, beta-naphthoflavone and trout CYP1A1 peptide antibody. | 1995 | Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. | pmid:7599976 |
Pedersen AO et al. | Effects of ionic strength and pH on the binding of medium-chain fatty acids to human serum albumin. | 1995 | Eur. J. Biochem. | pmid:7588780 |
Redondo O et al. | Comparative kinetic study of lipases A and B from Candida rugosa in the hydrolysis of lipid p-nitrophenyl esters in mixed micelles with Triton X-100. | 1995 | Biochim. Biophys. Acta | pmid:7827103 |
Ramarao MK et al. | Identification by in vitro mutagenesis of the interaction of two segments of C2MstC1, a chimera of cytochromes P450 2C2 and P450 2C1. | 1995 | J. Biol. Chem. | pmid:7829524 |
Hermansen JE | Prediction of milk fatty acid profile in dairy cows fed dietary fat differing in fatty acid composition. | 1995 | J. Dairy Sci. | pmid:7790578 |
Abdel-Fattah G et al. | Regulation of guinea pig very low density lipoprotein secretion rates by dietary fat saturation. | 1995 | J. Lipid Res. | pmid:7665997 |
Godet MC et al. | Inclusion/exclusion of fatty acids in amylose complexes as a function of the fatty acid chain length. | 1995 | Int. J. Biol. Macromol. | pmid:8789347 |
Geissdörfer W et al. | Two genes encoding proteins with similarities to rubredoxin and rubredoxin reductase are required for conversion of dodecane to lauric acid in Acinetobacter calcoaceticus ADP1. | 1995 | Microbiology (Reading, Engl.) | pmid:7670642 |
Chaurasia CS et al. | Biochemical characterization of lauric acid omega-hydroxylation by a CYP4A1/NADPH-cytochrome P450 reductase fusion protein. | 1995 | Arch. Biochem. Biophys. | pmid:7872779 |
Schwab US et al. | Lauric and palmitic acid-enriched diets have minimal impact on serum lipid and lipoprotein concentrations and glucose metabolism in healthy young women. | 1995 | J. Nutr. | pmid:7876922 |
Lee CK et al. | Transdermal delivery of theophylline using an ethanol/panasate 800-ethylcellulose gel preparation. | 1995 | Biol. Pharm. Bull. | pmid:7735237 |
Temme EH et al. | Comparison of the effects of diets enriched in lauric, palmitic, or oleic acids on serum lipids and lipoproteins in healthy women and men. | 1996 | Am. J. Clin. Nutr. | pmid:8644684 |
Bambal RB and Hanzlik RP | Active site structure and substrate specificity of cytochrome P450 4A1: steric control of ligand approach perpendicular to heme plane. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8605007 |
Winkler GB et al. | Fat absorption following small intestinal transplantation. | 1996 | Transplant. Proc. | pmid:8907942 |
Constantinides PP et al. | Water-in-oil microemulsions containing medium-chain fatty acids/salts: formulation and intestinal absorption enhancement evaluation. | 1996 | Pharm. Res. | pmid:8932438 |
Kemp PM et al. | Whole blood levels of dodecanoic acid, a routinely detectable forensic marker for a genetic disease often misdiagnosed as sudden infant death syndrome (SIDS): MCAD deficiency. | 1996 | Am J Forensic Med Pathol | pmid:8838477 |
Murataliev MB and Feyereisen R | Functional interactions in cytochrome P450BM3. Fatty acid substrate binding alters electron-transfer properties of the flavoprotein domain. | 1996 | Biochemistry | pmid:8942669 |
Ross KF et al. | Comment on "Whole blood levels of dodecanoic acid, a routinely detectable forensic marker for a genetic disease often misdiagnosed as sudden infant death syndrome (SIDS): MCAD deficiency". | 1996 | Am J Forensic Med Pathol | pmid:8947364 |
Hiratsuka M et al. | Sex differences in constitutive level of renal lauric acid hydroxylase activities and CYP4A-related proteins in mice. | 1996 | Biol. Pharm. Bull. | pmid:8860949 |
Wang MH et al. | Cloning, sequencing, and cDNA-directed expression of the rat renal CYP4A2: arachidonic acid omega-hydroxylation and 11,12-epoxidation by CYP4A2 protein. | 1996 | Arch. Biochem. Biophys. | pmid:8954571 |
Charbon V et al. | Targeting of drug to the hepatocytes by fatty acids. Influence of the carrier (albumin or galactosylated albumin) on the fate of the fatty acids and their analogs. | 1996 | Pharm. Res. | pmid:8668674 |
Kinderlerer JL et al. | Effect of medium-chain fatty acids in mould ripened cheese on the growth of Listeria monocytogenes. | 1996 | J. Dairy Res. | pmid:8933308 |
Kragh-Hansen U et al. | High-affinity binding of laurate to naturally occurring mutants of human serum albumin and proalbumin. | 1996 | Biochem. J. | pmid:9003380 |
Powell PK et al. | Identification of CYP4A11 as the major lauric acid omega-hydroxylase in human liver microsomes. | 1996 | Arch. Biochem. Biophys. | pmid:8914854 |
Vickers AE et al. | Hydroxyethyl cyclosporin A induces and decreases P4503A and P-glycoprotein levels in rat liver. | 1996 | Xenobiotica | pmid:8851819 |
Petschow BW et al. | Susceptibility of Helicobacter pylori to bactericidal properties of medium-chain monoglycerides and free fatty acids. | 1996 | Antimicrob. Agents Chemother. | pmid:8834870 |
Sherrington EJ et al. | Lack of effect of different dietary saturated fatty acids on adipose tissue deposition in the rat. | 1996 | Biochem. Soc. Trans. | pmid:8736816 |