lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with lauric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Mo FF et al. | Acute hyperglycemia is related to gastrointestinal symptoms in motion sickness: an experimental study. | 2012 | Physiol. Behav. | pmid:21907224 |
Kadu CA et al. | Bioactive constituents in Prunus africana: geographical variation throughout Africa and associations with environmental and genetic parameters. | 2012 | Phytochemistry | pmid:22795601 |
Asai T et al. | Cyclic glycolipids from glandular trichome exudates of Cerastium glomeratum. | 2012 | Phytochemistry | pmid:22854496 |
Afitlhile MM et al. | Labeling of major plant lipids and jasmonic acid using [1-(14C)] lauric acid. | 2004 | Phytochemistry | pmid:15464155 |
Nischwitz C et al. | Use of Fatty Acid Methyl Ester Profiles to Compare Copper-Tolerant and Copper-Sensitive Strains of Pantoea ananatis. | 2007 | Phytopathology | pmid:18943688 |
Renard-Merlier D et al. | Changes in C12:0, C18:1, C18:2 and C20:2 fatty acid content in wheat treated with resistance inducers and infected by powdery mildew. | 2009 | Plant Biol (Stuttg) | pmid:19121116 |
Li H et al. | Cytochrome P450 family member CYP704B2 catalyzes the {omega}-hydroxylation of fatty acids and is required for anther cutin biosynthesis and pollen exine formation in rice. | 2010 | Plant Cell | pmid:20086189 |
Xu J et al. | The ABORTED MICROSPORES regulatory network is required for postmeiotic male reproductive development in Arabidopsis thaliana. | 2010 | Plant Cell | pmid:20118226 |
Morant M et al. | CYP703 is an ancient cytochrome P450 in land plants catalyzing in-chain hydroxylation of lauric acid to provide building blocks for sporopollenin synthesis in pollen. | 2007 | Plant Cell | pmid:17496121 |
Kim SS et al. | LAP6/POLYKETIDE SYNTHASE A and LAP5/POLYKETIDE SYNTHASE B encode hydroxyalkyl α-pyrone synthases required for pollen development and sporopollenin biosynthesis in Arabidopsis thaliana. | 2010 | Plant Cell | pmid:21193570 |
Grausem B et al. | CYP77A19 and CYP77A20 characterized from Solanum tuberosum oxidize fatty acids in vitro and partially restore the wild phenotype in an Arabidopsis thaliana cutin mutant. | 2014 | Plant Cell Environ. | pmid:24520956 |
Suzuki T et al. | Identification of kaonashi mutants showing abnormal pollen exine structure in Arabidopsis thaliana. | 2008 | Plant Cell Physiol. | pmid:18779216 |
Lekshmi Sheela D et al. | In Silico and Wet Lab Studies Reveal the Cholesterol Lowering Efficacy of Lauric Acid, a Medium Chain Fat of Coconut Oil. | 2016 | Plant Foods Hum Nutr | pmid:27679437 |
Larson TR and Graham IA | Technical Advance: a novel technique for the sensitive quantification of acyl CoA esters from plant tissues. | 2001 | Plant J. | pmid:11169187 |
Koo AJ et al. | Identification of a plastid acyl-acyl carrier protein synthetase in Arabidopsis and its role in the activation and elongation of exogenous fatty acids. | 2005 | Plant J. | pmid:16262711 |
Dobritsa AA et al. | CYP704B1 is a long-chain fatty acid omega-hydroxylase essential for sporopollenin synthesis in pollen of Arabidopsis. | 2009 | Plant Physiol. | pmid:19700560 |
Quilichini TD et al. | ATP-binding cassette transporter G26 is required for male fertility and pollen exine formation in Arabidopsis. | 2010 | Plant Physiol. | pmid:20732973 |
Joyard J and Stumpf PK | Synthesis of Long-Chain Acyl-CoA in Chloroplast Envelope Membranes. | 1981 | Plant Physiol. | pmid:16661656 |
Benveniste I et al. | Cytochrome P-450-Dependent omega-Hydroxylation of Lauric Acid by Microsomes from Pea Seedlings. | 1982 | Plant Physiol. | pmid:16662431 |
Cao YZ and Huang AH | Acyl coenzyme a preference of diacylglycerol acyltransferase from the maturing seeds of cuphea, maize, rapeseed, and canola. | 1987 | Plant Physiol. | pmid:16665518 |
Saffert A et al. | A dual function alpha-dioxygenase-peroxidase and NAD(+) oxidoreductase active enzyme from germinating pea rationalizing alpha-oxidation of fatty acids in plants. | 2000 | Plant Physiol. | pmid:10938370 |
Nguyen HT et al. | Metabolic engineering of seeds can achieve levels of omega-7 fatty acids comparable with the highest levels found in natural plant sources. | 2010 | Plant Physiol. | pmid:20943853 |
Dussert S et al. | Comparative transcriptome analysis of three oil palm fruit and seed tissues that differ in oil content and fatty acid composition. | 2013 | Plant Physiol. | pmid:23735505 |
Zhang D et al. | OsC6, encoding a lipid transfer protein, is required for postmeiotic anther development in rice. | 2010 | Plant Physiol. | pmid:20610705 |
Brechenmacher L et al. | Soybean metabolites regulated in root hairs in response to the symbiotic bacterium Bradyrhizobium japonicum. | 2010 | Plant Physiol. | pmid:20534735 |
Austin-Brown SL and Chapman KD | Inhibition of phospholipase D alpha by N-acylethanolamines. | 2002 | Plant Physiol. | pmid:12177503 |
Dobritsa AA et al. | LAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis. | 2010 | Plant Physiol. | pmid:20442277 |
Lawo NC et al. | The volatile metabolome of grapevine roots: first insights into the metabolic response upon phylloxera attack. | 2011 | Plant Physiol. Biochem. | pmid:21764593 |
Crane J et al. | Triacylglycerols determine the unusual storage physiology of Cuphea seed. | 2003 | Planta | pmid:12743824 |
Hunzicker GM | A novel regulatory system in plants involving medium-chain fatty acids. | 2009 | Planta | pmid:19876644 |
Wiberg E et al. | Fatty acid distribution and lipid metabolism in developing seeds of laurate-producing rape (Brassica napus L.). | 1997 | Planta | pmid:9431681 |
Wiberg E et al. | The distribution of caprylate, caprate and laurate in lipids from developing and mature seeds of transgenic Brassica napus L. | 2000 | Planta | pmid:11219581 |
Madey E et al. | Isolation and characterization of lipid in phloem sap of canola. | 2002 | Planta | pmid:11925046 |
Hernández-Galicia E et al. | Monoglycerides and fatty acids from Ibervillea sonorae root: isolation and hypoglycemic activity. | 2007 | Planta Med. | pmid:17318782 |
Rösler TW et al. | Analysis of the hydrodistillate from the fruits of Serenoa repens. | 2009 | Planta Med. | pmid:19140098 |
Bridgham JT et al. | Protein evolution by molecular tinkering: diversification of the nuclear receptor superfamily from a ligand-dependent ancestor. | 2010 | PLoS Biol. | pmid:20957188 |
Chopra T et al. | Novel intermolecular iterative mechanism for biosynthesis of mycoketide catalyzed by a bimodular polyketide synthase. | 2008 | PLoS Biol. | pmid:18613748 |
Mazella J et al. | Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design. | 2010 | PLoS Biol. | pmid:20405001 |
Spierings E et al. | Phenotype frequencies of autosomal minor histocompatibility antigens display significant differences among populations. | 2007 | PLoS Genet. | pmid:17604453 |
Goh KS and Li CW | A photocytes-associated fatty acid-binding protein from the light organ of adult Taiwanese firefly, Luciola cerata. | 2011 | PLoS ONE | pmid:22242133 |
Sanchez SA et al. | Sucrose monoester micelles size determined by Fluorescence Correlation Spectroscopy (FCS). | 2011 | PLoS ONE | pmid:22216230 |
Kenny JG et al. | The Staphylococcus aureus response to unsaturated long chain free fatty acids: survival mechanisms and virulence implications. | 2009 | PLoS ONE | pmid:19183815 |
Horbul JE et al. | Herpes simplex virus-induced epithelial damage and susceptibility to human immunodeficiency virus type 1 infection in human cervical organ culture. | 2011 | PLoS ONE | pmid:21818356 |
Carrington LB et al. | A re-examination of Wolbachia-induced cytoplasmic incompatibility in California Drosophila simulans. | 2011 | PLoS ONE | pmid:21799900 |
Schaefers MM et al. | Epithelial proinflammatory response and curcumin-mediated protection from staphylococcal toxic shock syndrome toxin-1. | 2012 | PLoS ONE | pmid:22431984 |
RodrÃguez-Navarro A | A simple index for the high-citation tail of citation distribution to quantify research performance in countries and institutions. | 2011 | PLoS ONE | pmid:21647383 |
Zhang S et al. | Functional synchronization of biological rhythms in a tritrophic system. | 2010 | PLoS ONE | pmid:20552008 |
Inácio ÂS et al. | In vitro surfactant structure-toxicity relationships: implications for surfactant use in sexually transmitted infection prophylaxis and contraception. | 2011 | PLoS ONE | pmid:21603626 |
Wodarczyk C et al. | Nephrocystin-1 forms a complex with polycystin-1 via a polyproline motif/SH3 domain interaction and regulates the apoptotic response in mammals. | 2010 | PLoS ONE | pmid:20856870 |
Lee DM et al. | Oxidative stress and inflammation in renal patients and healthy subjects. | 2011 | PLoS ONE | pmid:21829457 |