lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

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Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Acne Vulgaris D000152 35 associated lipids
Albuminuria D000419 18 associated lipids
Bird Diseases D001715 4 associated lipids
Body Weight D001835 333 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Cerebral Infarction D002544 6 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Hemolysis D006461 131 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lung Neoplasms D008175 171 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Nephrosis, Lipoid D009402 2 associated lipids
Obesity, Morbid D009767 8 associated lipids
Prostatic Hyperplasia D011470 20 associated lipids
Seizures D012640 87 associated lipids
Starvation D013217 47 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Thrombosis D013927 49 associated lipids
Vasculitis D014657 14 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Brain Infarction D020520 17 associated lipids
Stroke D020521 32 associated lipids
Atherosclerosis D050197 85 associated lipids
Vascular System Injuries D057772 2 associated lipids
Peripheral Arterial Disease D058729 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

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Authors Title Published Journal PubMed Link
Mangeat B et al. HIV-1 Vpu neutralizes the antiviral factor Tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradation. 2009 PLoS Pathog. pmid:19730691
Wang S et al. Insertion of an esterase gene into a specific locust pathogen (Metarhizium acridum) enables it to infect caterpillars. 2011 PLoS Pathog. pmid:21731492
Ittig S et al. The lipopolysaccharide from Capnocytophaga canimorsus reveals an unexpected role of the core-oligosaccharide in MD-2 binding. 2012 PLoS Pathog. pmid:22570611
Wilks J and Golovkina T Influence of microbiota on viral infections. 2012 PLoS Pathog. pmid:22615558
Wexler-Cohen Y and Shai Y Membrane-anchored HIV-1 N-heptad repeat peptides are highly potent cell fusion inhibitors via an altered mode of action. 2009 PLoS Pathog. pmid:19593361
Ponton F et al. Nutritional immunology: a multi-dimensional approach. 2011 PLoS Pathog. pmid:22144886
Poudrier J and Roger M Dendritic cell status modulates the outcome of HIV-related B cell disease progression. 2011 PLoS Pathog. pmid:21901089
Zhou Z et al. HIV-1 efficient entry in inner foreskin is mediated by elevated CCL5/RANTES that recruits T cells and fuels conjugate formation with Langerhans cells. 2011 PLoS Pathog. pmid:21738469
Wijewardana V et al. Early myeloid dendritic cell dysregulation is predictive of disease progression in simian immunodeficiency virus infection. 2010 PLoS Pathog. pmid:21203477
Li H et al. High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men. 2010 PLoS Pathog. pmid:20485520
Batovska DI et al. Antibacterial study of the medium chain fatty acids and their 1-monoglycerides: individual effects and synergistic relationships. 2009 Pol. J. Microbiol. pmid:19469285
Cook GC The medical career of Robert Seymour Bridges, FRCP (1844-1930): physician and Poet Laureate. 2002 Postgrad Med J pmid:12357018
Dawson PL et al. Effect of lauric acid and nisin-impregnated soy-based films on the growth of Listeria monocytogenes on turkey bologna. 2002 Poult. Sci. pmid:12033424
Zeitz JO et al. Effects of dietary fats rich in lauric and myristic acid on performance, intestinal morphology, gut microbes, and meat quality in broilers. 2015 Poult. Sci. pmid:26240391
Spencer GK and Waldroup PW The influence of amprolium and butynorate on growth rate and feed utilization by large white turkeys. 1985 Poult. Sci. pmid:4001047
Hardwick JP et al. PPAR/RXR Regulation of Fatty Acid Metabolism and Fatty Acid omega-Hydroxylase (CYP4) Isozymes: Implications for Prevention of Lipotoxicity in Fatty Liver Disease. 2009 PPAR Res pmid:20300478
Pinaire JA and Reifel-Miller A Therapeutic potential of retinoid x receptor modulators for the treatment of the metabolic syndrome. 2007 PPAR Res pmid:17497022
Robertson LW et al. Suppression of peroxisomal enzyme activities and cytochrome P450 4A isozyme expression by congeneric polybrominated and polychlorinated biphenyls. 2007 PPAR Res pmid:18274624
Runge-Morris M and Kocarek TA Regulation of sulfotransferase and UDP-glucuronosyltransferase gene expression by the PPARs. 2009 PPAR Res pmid:19680455
Ball D Robert Bridges. Doctor of Medicine and Poet Laureate. 1974 Practitioner pmid:4614250
Claassen E and van Rooijen N A comparative study on the effectiveness of various procedures for attachment of two proteins (L-asparaginase and horse radish peroxidase) to the surface of liposomes. 1983 Prep. Biochem. pmid:6878179
Anis SNS et al. In vivo and in vitro depolymerizations of intracellular medium-chain-length poly-3-hydroxyalkanoates produced by Pseudomonas putida Bet001. 2017 Prep. Biochem. Biotechnol. pmid:28635367
Kromhout D et al. Dietary saturated and trans fatty acids and cholesterol and 25-year mortality from coronary heart disease: the Seven Countries Study. 1995 Prev Med pmid:7644455
Hirano T Interleukin 6 in autoimmune and inflammatory diseases: a personal memoir. 2010 Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. pmid:20689230
Faulkner KM et al. Electrocatalytically driven omega-hydroxylation of fatty acids using cytochrome P450 4A1. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7644480
Motoyama Y et al. Effect of TFC-612, a 7-thia prostaglandin E1 derivative, on a peripheral arterial occlusive disease model in rats. 1995 Prostaglandins pmid:7652186
Irmisch G et al. Relationships between fatty acids and psychophysiological parameters in depressive inpatients under experimentally induced stress. 2006 Prostaglandins Leukot. Essent. Fatty Acids pmid:16343879
Goodfriend TL et al. Plasma aldosterone, plasma lipoproteins, obesity and insulin resistance in humans. 1999 May-Jun Prostaglandins Leukot. Essent. Fatty Acids pmid:10471129
Kuipers RS et al. Milk in the island of Chole [Tanzania] is high in lauric, myristic, arachidonic and docosahexaenoic acids, and low in linoleic acid reconstructed diet of infants born to our ancestors living in tropical coastal regions. 2007 Prostaglandins Leukot. Essent. Fatty Acids pmid:17383169
Lopez D et al. Lauric acid dependent enhancement in hepatic SCPx protein requires an insulin deficient environment. 2008 Prostaglandins Leukot. Essent. Fatty Acids pmid:18187312
Srivastava KC Effect of some saturated and unsaturated fatty acids on in vitro platelet utilization of arachidonic acid. 1979 Prostaglandins Med pmid:550161
Rowlatt B et al. Chain length-dependent cooperativity in fatty acid binding and oxidation by cytochrome P450BM3 (CYP102A1). 2011 Protein Cell pmid:21904981
Collini M et al. Competitive binding of fatty acids and the fluorescent probe 1-8-anilinonaphthalene sulfonate to bovine beta-lactoglobulin. 2003 Protein Sci. pmid:12876309
Feenstra KA et al. Combining substrate dynamics, binding statistics, and energy barriers to rationalize regioselective hydroxylation of octane and lauric acid by CYP102A1 and mutants. 2007 Protein Sci. pmid:17322527
Rupasinghe SG et al. Molecular definitions of fatty acid hydroxylases in Arabidopsis thaliana. 2007 Proteins pmid:17427946
Chang YT and Loew GH Homology modeling and substrate binding study of human CYP4A11 enzyme. 1999 Proteins pmid:10024026
Churchward MA et al. Enhanced detergent extraction for analysis of membrane proteomes by two-dimensional gel electrophoresis. 2005 Proteome Sci pmid:15941475
Thomson AB Resection of rabbit ileum: effect on jejunal structure and carrier-mediated and passive uptake. 1986 Q J Exp Physiol pmid:3952260
Hlongwane C et al. Comparative quantitative fatty acid analysis of triacylglycerols using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and gas chromatography. 2001 Rapid Commun. Mass Spectrom. pmid:11675670
Ayorinde FO et al. Determination of the fatty acid composition of saponified vegetable oils using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. 2000 Rapid Commun. Mass Spectrom. pmid:10775096
Liu Y et al. Graphene and graphene oxide: two ideal choices for the enrichment and ionization of long-chain fatty acids free from matrix-assisted laser desorption/ionization matrix interference. 2011 Rapid Commun. Mass Spectrom. pmid:22006384
Zemaitis M et al. Identification of omega hydroxy fatty acids in biological samples as their pentafluoropropyl derivatives by gas chromatography/mass spectrometry with positive and negative ion detection. 2002 Rapid Commun. Mass Spectrom. pmid:12125016
Qian X [Speech by Dr. Qian Xinzhong, Minister-in-charge of the State Family Planning Commission and Laureate of the United Nations Population Award, at the United Nations Population Award presentation ceremony (30 September 1983)]. 1983 Renkou Yanjiu pmid:12159402
Siess MH et al. [The effect of cholesterol and the nature of dietary fatty acids on the activities of some microsomal monooxygenases in the rat liver]. 1983 Reprod Nutr Dev pmid:6405460
Guesnet P et al. [Nutritional correction of an excess of unsaturated fatty acids in the body lipids of the growing rat]. 1984 Reprod Nutr Dev pmid:6484304
Jan S et al. Myristic acid increases delta6-desaturase activity in cultured rat hepatocytes. 2004 Mar-Apr Reprod. Nutr. Dev. pmid:15270551
Rioux V et al. Although it is rapidly metabolized in cultured rat hepatocytes, lauric acid is used for protein acylation. 2003 Sep-Oct Reprod. Nutr. Dev. pmid:15005371
Carlson GP Formation of fatty acid propyl esters in liver, lung and pancreas of rats administered 1-propanol. 1993 Res. Commun. Chem. Pathol. Pharmacol. pmid:8210685
Silva RA et al. Characterization of indigenous Rhodococcus sp. 602, a strain able to accumulate triacylglycerides from naphthyl compounds under nitrogen-starved conditions. 2010 Res. Microbiol. pmid:20144706
Szotáková B et al. Comparison of in vitro activities of biotransformation enzymes in pig, cattle, goat and sheep. 2004 Res. Vet. Sci. pmid:14659728