lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with lauric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Komata Y et al. | Effect of fatty acid on the accumulation of thiamine disulfide in rat skin. | 1994 | Biol. Pharm. Bull. | pmid:7920438 |
Amet Y et al. | Evidence that cytochrome P450 2E1 is involved in the (omega-1)-hydroxylation of lauric acid in rat liver microsomes. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8093035 |
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Grundy SM | Influence of stearic acid on cholesterol metabolism relative to other long-chain fatty acids. | 1994 | Am. J. Clin. Nutr. | pmid:7977157 |
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Preobrazhenskaia TA et al. | [Comparative effect of polymyxin B on lipid bilayer membranes with different lipid composition]. | 1994 Nov-Dec | Biofizika | pmid:7873621 |
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Motoyama Y et al. | Effect of TFC-612, a 7-thia prostaglandin E1 derivative, on a peripheral arterial occlusive disease model in rats. | 1995 | Prostaglandins | pmid:7652186 |
Smith SW and Anderson BD | Human skin permeability enhancement by lauric acid under equilibrium aqueous conditions. | 1995 | J Pharm Sci | pmid:7658343 |
Kromhout D et al. | Dietary saturated and trans fatty acids and cholesterol and 25-year mortality from coronary heart disease: the Seven Countries Study. | 1995 | Prev Med | pmid:7644455 |
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Pronczuk A et al. | Plasma lipids are affected similarly by dietary lauric or palmitic acid in gerbils and monkeys. | 1995 | Lipids | pmid:8614307 |
Amet Y et al. | Validation of the (omega-1)-hydroxylation of lauric acid as an in vitro substrate probe for human liver CYP2E1. | 1995 | Biochem. Pharmacol. | pmid:8615855 |
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Castle PJ et al. | Human liver lauric acid hydroxylase activities. | 1995 | Drug Metab. Dispos. | pmid:8654190 |
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Alterman MA et al. | Heteroatom substitution shifts regioselectivity of lauric acid metabolism from omega-hydroxylation to (omega-1)-oxidation. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7575514 |
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Godet MC et al. | Inclusion/exclusion of fatty acids in amylose complexes as a function of the fatty acid chain length. | 1995 | Int. J. Biol. Macromol. | pmid:8789347 |
Geissdörfer W et al. | Two genes encoding proteins with similarities to rubredoxin and rubredoxin reductase are required for conversion of dodecane to lauric acid in Acinetobacter calcoaceticus ADP1. | 1995 | Microbiology (Reading, Engl.) | pmid:7670642 |
Chaurasia CS et al. | Biochemical characterization of lauric acid omega-hydroxylation by a CYP4A1/NADPH-cytochrome P450 reductase fusion protein. | 1995 | Arch. Biochem. Biophys. | pmid:7872779 |
Schwab US et al. | Lauric and palmitic acid-enriched diets have minimal impact on serum lipid and lipoprotein concentrations and glucose metabolism in healthy young women. | 1995 | J. Nutr. | pmid:7876922 |
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Winkler GB et al. | Fat absorption following small intestinal transplantation. | 1996 | Transplant. Proc. | pmid:8907942 |
Constantinides PP et al. | Water-in-oil microemulsions containing medium-chain fatty acids/salts: formulation and intestinal absorption enhancement evaluation. | 1996 | Pharm. Res. | pmid:8932438 |
Kemp PM et al. | Whole blood levels of dodecanoic acid, a routinely detectable forensic marker for a genetic disease often misdiagnosed as sudden infant death syndrome (SIDS): MCAD deficiency. | 1996 | Am J Forensic Med Pathol | pmid:8838477 |
Murataliev MB and Feyereisen R | Functional interactions in cytochrome P450BM3. Fatty acid substrate binding alters electron-transfer properties of the flavoprotein domain. | 1996 | Biochemistry | pmid:8942669 |
Ross KF et al. | Comment on "Whole blood levels of dodecanoic acid, a routinely detectable forensic marker for a genetic disease often misdiagnosed as sudden infant death syndrome (SIDS): MCAD deficiency". | 1996 | Am J Forensic Med Pathol | pmid:8947364 |
Hiratsuka M et al. | Sex differences in constitutive level of renal lauric acid hydroxylase activities and CYP4A-related proteins in mice. | 1996 | Biol. Pharm. Bull. | pmid:8860949 |
Wang MH et al. | Cloning, sequencing, and cDNA-directed expression of the rat renal CYP4A2: arachidonic acid omega-hydroxylation and 11,12-epoxidation by CYP4A2 protein. | 1996 | Arch. Biochem. Biophys. | pmid:8954571 |
Charbon V et al. | Targeting of drug to the hepatocytes by fatty acids. Influence of the carrier (albumin or galactosylated albumin) on the fate of the fatty acids and their analogs. | 1996 | Pharm. Res. | pmid:8668674 |
Kinderlerer JL et al. | Effect of medium-chain fatty acids in mould ripened cheese on the growth of Listeria monocytogenes. | 1996 | J. Dairy Res. | pmid:8933308 |
Kragh-Hansen U et al. | High-affinity binding of laurate to naturally occurring mutants of human serum albumin and proalbumin. | 1996 | Biochem. J. | pmid:9003380 |
Bookstaff RC et al. | Effects of doxylamine succinate on thyroid hormone balance and enzyme induction in mice. | 1996 | Toxicol. Appl. Pharmacol. | pmid:8975784 |
Petschow BW et al. | Susceptibility of Helicobacter pylori to bactericidal properties of medium-chain monoglycerides and free fatty acids. | 1996 | Antimicrob. Agents Chemother. | pmid:8834870 |
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