lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with lauric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Samartsev VN et al. | Comparative study on uncoupling effects of laurate and lauryl sulfate on rat liver and skeletal muscle mitochondria. | 2000 | Biochim. Biophys. Acta | pmid:10924910 |
Saffert A et al. | A dual function alpha-dioxygenase-peroxidase and NAD(+) oxidoreductase active enzyme from germinating pea rationalizing alpha-oxidation of fatty acids in plants. | 2000 | Plant Physiol. | pmid:10938370 |
Santoyo S and Ygartua P | Effect of skin pretreatment with fatty acids on percutaneous absorption and skin retention of piroxicam after its topical application. | 2000 | Eur J Pharm Biopharm | pmid:10962234 |
Hashemi E et al. | Stability of cytochrome P450 proteins in cultured precision-cut rat liver slices. | 2000 | Toxicology | pmid:10967402 |
Toshima Y et al. | A new model of cerebral microthrombosis in rats and the neuroprotective effect of a Rho-kinase inhibitor. | 2000 | Stroke | pmid:10978059 |
Giorgi M et al. | Cytochrome P450-dependent monooxygenase activities and their inducibility by classic P450 inducers in the liver, kidney, and nasal mucosa of male adult ring-necked pheasants. | 2000 | Toxicol. Appl. Pharmacol. | pmid:10986015 |
Imaishi H et al. | CYP78A1 preferentially expressed in developing inflorescences of Zea mays encoded a cytochrome P450-dependent lauric acid 12-monooxygenase. | 2000 | Biosci. Biotechnol. Biochem. | pmid:10993158 |
Nielsen AD et al. | Thermochemistry of the specific binding of C12 surfactants to bovine serum albumin. | 2000 | Biochim. Biophys. Acta | pmid:11004550 |
DeLany JP et al. | Differential oxidation of individual dietary fatty acids in humans. | 2000 | Am. J. Clin. Nutr. | pmid:11010930 |
Sidhu SS et al. | Fatty acid-induced cholecystokinin secretion and changes in intracellular Ca2+ in two enteroendocrine cell lines, STC-1 and GLUTag. | 2000 | J. Physiol. (Lond.) | pmid:11018115 |
Vogel S et al. | Characterization of a new member of the fatty acid-binding protein family that binds all-trans-retinol. | 2001 | J. Biol. Chem. | pmid:11022035 |
Pereira JR et al. | Inversion in the change of the refractive index and memory effect near the nematic-isotropic phase transition in a lyotropic liquid crystal. | 2000 | Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics | pmid:11031592 |
Buhler DR et al. | Effects of 17beta-estradiol and testosterone on hepatic mRNA/protein levels and catalytic activities of CYP2M1, CYP2K1, and CYP3A27 in rainbow trout (Oncorhynchus mykiss). | 2000 | Toxicol. Appl. Pharmacol. | pmid:11032764 |
Yang YH et al. | Heterologous expression of CYP2K1 and identification of the expressed protein (BV-CYP2K1) as lauric acid (omega-1)-hydroxylase and aflatoxin B1 exo-epoxidase. | 2000 | Drug Metab. Dispos. | pmid:11038153 |
Soetanto K and Chan M | Study on the lifetime and attenuation properties of microbubbles coated with carboxylic acid salts. | 2000 | Ultrasonics | pmid:11106009 |
Loughran PA et al. | Identification of unique amino acids that modulate CYP4A7 activity. | 2000 | Biochemistry | pmid:11106489 |
Pantaler E et al. | Acceleration of phospholipid flip-flop in the erythrocyte membrane by detergents differing in polar head group and alkyl chain length. | 2000 | Biochim. Biophys. Acta | pmid:11118549 |
Morais PC et al. | Raman spectroscopy in magnetic fluids. | 2001 | Biomol. Eng. | pmid:11163750 |
Oh HJ et al. | Effects of vehicles and enhancers on transdermal delivery of melatonin. | 2001 | Int J Pharm | pmid:11165821 |
Larson TR and Graham IA | Technical Advance: a novel technique for the sensitive quantification of acyl CoA esters from plant tissues. | 2001 | Plant J. | pmid:11169187 |
Abigor RD et al. | Lipase-catalysed production of biodiesel fuel from some Nigerian lauric oils. | 2000 | Biochem. Soc. Trans. | pmid:11171279 |
Kikuta Y et al. | Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14. | 2000 | Arch. Biochem. Biophys. | pmid:11185557 |
Byrdwell WC and Neff WE | Autoxidation products of normal and genetically modified canola oil varieties determined using liquid chromatography with mass spectrometric detection. | 2001 | J Chromatogr A | pmid:11206810 |
Wiberg E et al. | The distribution of caprylate, caprate and laurate in lipids from developing and mature seeds of transgenic Brassica napus L. | 2000 | Planta | pmid:11219581 |
Coon J and Hunter R | Properties of conjugated protein immunogens which selectively stimulate delayed-type hypersensitivity. | 1975 | J. Immunol. | pmid:1123546 |
Ngo S et al. | Cytochrome P450 4A, peroxisomal enzymes and nicotinamide cofactors in koala liver. | 2000 | Comp. Biochem. Physiol. C Toxicol. Pharmacol. | pmid:11246504 |
Kantor HL and Prestegard JH | Fusion of fatty acid containing lecithin vesicles. | 1975 | Biochemistry | pmid:1125198 |
Jørgensen JR et al. | In vivo absorption of medium-chain fatty acids by the rat colon exceeds that of short-chain fatty acids. | 2001 | Gastroenterology | pmid:11266379 |
Lee JY et al. | Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4. | 2001 | J. Biol. Chem. | pmid:11278967 |
Vessey DA | Isolation and preliminary characterization of the medium-chain fatty acid:CoA ligase responsible for activation of short- and medium-chain fatty acids in colonic mucosa from swine. | 2001 | Dig. Dis. Sci. | pmid:11281196 |
Orellana B M et al. | Oxidative stress, microsomal and peroxisomal fatty acid oxidation in the liver of rats treated with acetone. | 2001 | Comp. Biochem. Physiol. C Toxicol. Pharmacol. | pmid:11301292 |
Aoki T et al. | Cholesterol-lowering effect of NK-104, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, in guinea pig model of hyperlipidemia. | 2001 | Arzneimittelforschung | pmid:11304935 |
Echtay KS et al. | Role of intrahelical arginine residues in functional properties of uncoupling protein (UCP1). | 2001 | Biochemistry | pmid:11318647 |
Cunha MT et al. | Effect of salts and surfactants on the partitioning of Fusarium solani pisi cutinase in aqueous two-phase systems of thermoseparating ethylene oxide/propylene oxide random copolymer and hydroxypropyl starch. | 2000 | Bioseparation | pmid:11321518 |
Glover ED | 2000 Research Laureate Medallion Award. | Am J Health Behav | pmid:11322613 | |
Simonyan RA et al. | Cold-induced changes in the energy coupling and the UCP3 level in rodent skeletal muscles. | 2001 | Biochim. Biophys. Acta | pmid:11334791 |
Stott PW et al. | Mechanistic study into the enhanced transdermal permeation of a model beta-blocker, propranolol, by fatty acids: a melting point depression effect. | 2001 | Int J Pharm | pmid:11337176 |
Ichihara K et al. | Fatty acid omega and (omega-1)-Hydroxylation in rabbit intestinal mucosa microsomes. | 1979 | J. Biochem. | pmid:113393 |
Kothari HV | Purification and properties of aortic cholesteryl ester hydrolase. | 1975 | Lipids | pmid:1134220 |
Park SJ et al. | Biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyvalerate-co-3-hydroxyhexanoate) by metabolically engineered Escherichia coli strains. | 2001 | Biotechnol. Bioeng. | pmid:11353413 |
Loughran PA et al. | The kinetic and spectral characterization of the E. coli-expressed mammalian CYP4A7: cytochrome b5 effects vary with substrate. | 2001 | Arch. Biochem. Biophys. | pmid:11368012 |
Cowart LA et al. | Structural determinants of active site binding affinity and metabolism by cytochrome P450 BM-3. | 2001 | Arch. Biochem. Biophys. | pmid:11368173 |
Kragh-Hansen U et al. | Detergents as probes of hydrophobic binding cavities in serum albumin and other water-soluble proteins. | 2001 | Biophys. J. | pmid:11371462 |
Liebau M et al. | Bioadhesion of supramolecular structures at supported planar bilayers as studied by the quartz crystal microbalance. | 2001 | Eur. Biophys. J. | pmid:11372532 |
Kikuta Y et al. | Expression and induction of cytochrome P450s in rabbit parotid glands. | 2001 | Biochem. Pharmacol. | pmid:11389885 |
van Roermund CW et al. | Identification of a peroxisomal ATP carrier required for medium-chain fatty acid beta-oxidation and normal peroxisome proliferation in Saccharomyces cerevisiae. | 2001 | Mol. Cell. Biol. | pmid:11390660 |
Amet Y et al. | Adaptation to chronic ethanol administration emphasized by fatty acid hydroxylations in rat liver and kidney microsomes. | 2000 | Eur J Nutr | pmid:11395987 |
Gilep AA et al. | Reconstitution of the enzymatic activities of cytochrome P450s using recombinant flavocytochromes containing rat cytochrome b(5) fused to NADPH--cytochrome P450 reductase with various membrane-binding segments. | 2001 | Arch. Biochem. Biophys. | pmid:11396924 |
Imaoka S et al. | A transgenic mouse expressing human CYP4B1 in the liver. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11396967 |
Bartolotta S et al. | Effect of fatty acids on arenavirus replication: inhibition of virus production by lauric acid. | 2001 | Arch. Virol. | pmid:11402863 |