lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with lauric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Faciola AP and Broderick GA | Effects of feeding lauric acid or coconut oil on ruminal protozoa numbers, fermentation pattern, digestion, omasal nutrient flow, and milk production in dairy cows. | 2014 | J. Dairy Sci. | pmid:24931520 |
Hristov AN et al. | Effects of lauric and myristic acids on ruminal fermentation, production, and milk fatty acid composition in lactating dairy cows. | 2011 | J. Dairy Sci. | pmid:21183049 |
Hermansen JE | Prediction of milk fatty acid profile in dairy cows fed dietary fat differing in fatty acid composition. | 1995 | J. Dairy Sci. | pmid:7790578 |
Mills JK et al. | The effects of feeding medium-chain triglycerides on the growth, insulin responsiveness, and body composition of Holstein calves from birth to 85 kg of body weight. | 2010 | J. Dairy Sci. | pmid:20723699 |
Kinderlerer JL et al. | Effect of medium-chain fatty acids in mould ripened cheese on the growth of Listeria monocytogenes. | 1996 | J. Dairy Res. | pmid:8933308 |
Westergaard H and Dietschy JM | The mechanism whereby bile acid micelles increase the rate of fatty acid and cholesterol uptake into the intestinal mucosal cell. | 1976 | J. Clin. Invest. | pmid:932213 |
The Endocrine Society 2012 Laureate Awards. | 2012 | J. Clin. Endocrinol. Metab. | pmid:22869853 | |
Chopra IJ et al. | A competitive ligand binding assay for measurement of thyroid hormone-binding inhibitor in serum and tissues. | 1984 | J. Clin. Endocrinol. Metab. | pmid:6421865 |
Amet Y et al. | Simultaneous radiometric and fluorimetric detection of lauric acid metabolites using high-performance liquid chromatography following esterification with 4-bromomethyl-6,7-dimethoxycoumarin in human and rat liver microsomes. | 1996 | J. Chromatogr. B, Biomed. Appl. | pmid:8811432 |
Saito M et al. | 2-(5-hydrazinocarbonyl-2-oxazolyl)-5,6-dimethoxybenzothiazole as a precolumn fluorescence derivatization reagent for carboxylic acids in high-performance liquid chromatography and its application to the assay of fatty acids in human serum. | 1995 | J. Chromatogr. B, Biomed. Appl. | pmid:8788145 |
Dirven HA et al. | Determination of the cytochrome P-450 IV marker, omega-hydroxylauric acid, by high-performance liquid chromatography and fluorimetric detection. | 1991 | J. Chromatogr. | pmid:1860919 |
Maurich V et al. | p-nitrophenyllaurate: a substrate for the high-performance liquid chromatographic determination of lipase activity. | 1991 | J. Chromatogr. | pmid:1939456 |
Schulz CM et al. | Identification of new homoterpene esters from Dufour's gland of the ponerine ant Gnamptogenys striatula. | 2002 | J. Chem. Ecol. | pmid:12564799 |
Blatrix R et al. | Trail pheromone of ponerine ant Gnamptogenys striatula: 4-methylgeranyl esters from Dufour's gland. | 2002 | J. Chem. Ecol. | pmid:12564800 |
Smallegange RC et al. | The effect of aliphatic carboxylic acids on olfaction-based host-seeking of the malaria mosquito Anopheles gambiae sensu stricto. | 2009 | J. Chem. Ecol. | pmid:19626371 |
Matsumoto K et al. | Biosynthesis of glycolate-based polyesters containing medium-chain-length 3-hydroxyalkanoates in recombinant Escherichia coli expressing engineered polyhydroxyalkanoate synthase. | 2011 | J. Biotechnol. | pmid:21907740 |
Dietrich M et al. | Altering the regioselectivity of the subterminal fatty acid hydroxylase P450 BM-3 towards gamma- and delta-positions. | 2009 | J. Biotechnol. | pmid:18984016 |
Koreishi M et al. | Efficient Nepsilon-lauroyl-L-lysine production by recombinant epsilon-lysine acylase from Streptomyces mobaraensis. | 2009 | J. Biotechnol. | pmid:19433221 |
Hu QZ and Jang CH | Using liquid crystals for the label-free detection of catalase at aqueous-LC interfaces. | 2012 | J. Biotechnol. | pmid:22138010 |
Topakas E et al. | Comparison of mesophilic and thermophilic feruloyl esterases: characterization of their substrate specificity for methyl phenylalkanoates. | 2005 | J. Biotechnol. | pmid:15639097 |
Hirata Y et al. | Novel characteristics of sophorolipids, yeast glycolipid biosurfactants, as biodegradable low-foaming surfactants. | 2009 | J. Biosci. Bioeng. | pmid:19619862 |
Islam NN et al. | Synthesis and degradation of acyl peptide using enzyme from Pseudomonas aeruginosa. | 2008 | J. Biosci. Bioeng. | pmid:18397780 |
Maeda A et al. | Characterization of novel cholesterol esterase from Trichoderma sp. AS59 with high ability to synthesize steryl esters. | 2008 | J. Biosci. Bioeng. | pmid:18499049 |
Okamoto K et al. | Production of gamma-lactones by the brown-rot basidiomycete Piptoporus soloniensis. | 2002 | J. Biosci. Bioeng. | pmid:16233291 |
Wang Q and Nomura CT | Monitoring differences in gene expression levels and polyhydroxyalkanoate (PHA) production in Pseudomonas putida KT2440 grown on different carbon sources. | 2010 | J. Biosci. Bioeng. | pmid:20807680 |
Yamazaki E et al. | Kinetics of fatty acid binding ability of glycated human serum albumin. | 2005 | J. Biosci. | pmid:16184009 |
Ramesh KV et al. | Modeling the interactions of herbal drugs to beta-ketoacyl ACP synthase of Mycobacterium tuberculosis H37Rv. | 2008 | J. Biomol. Struct. Dyn. | pmid:18282003 |
Maity K et al. | Insights into the substrate specificity of a thioesterase Rv0098 of mycobacterium tuberculosis through X-ray crystallographic and molecular dynamics studies. | 2012 | J. Biomol. Struct. Dyn. | pmid:22292955 |
Pradhan P et al. | Comparative evaluation of heating ability and biocompatibility of different ferrite-based magnetic fluids for hyperthermia application. | 2007 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:16924619 |
Crépy L et al. | Evaluation of a bio-based hydrophobic cellulose laurate film as biomaterial--study on biodegradation and cytocompatibility. | 2012 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:22323390 |
Darvishi F et al. | Effect of plant oils upon lipase and citric acid production in Yarrowia lipolytica yeast. | 2009 | J. Biomed. Biotechnol. | pmid:19826636 |
Man D et al. | Effect of chlorotriphenyl derivatives of Sn and Pb upon biophysical properties of membranes. | 2009 | J. Biomed. Biotechnol. | pmid:19606258 |
Laurin D et al. | Exploration of the lysis mechanisms of leukaemic blasts by chimaeric T-cells. | 2010 | J. Biomed. Biotechnol. | pmid:20617141 |
Vottero E et al. | Role of residue 87 in substrate selectivity and regioselectivity of drug-metabolizing cytochrome P450 CYP102A1 M11. | 2011 | J. Biol. Inorg. Chem. | pmid:21567268 |
Chen CK et al. | The effect of mutation of F87 on the properties of CYP102A1-CYP4C7 chimeras: altered regiospecificity and substrate selectivity. | 2008 | J. Biol. Inorg. Chem. | pmid:18392864 |
Tanaka T et al. | Activation by saturated and monounsaturated fatty acids of the O2- -generating system in a cell-free preparation from neutrophils. | 1988 | J. Biol. Chem. | pmid:2843528 |
Okino N et al. | The reverse activity of human acid ceramidase. | 2003 | J. Biol. Chem. | pmid:12764132 |
Okita RT et al. | The omega- and (omega-1)-hydroxylase activities of prostaglandins A1 and E1 and lauric acid by pig kidney microsomes and a purified kidney cytochrome P-450. | 1981 | J. Biol. Chem. | pmid:6787046 |
Viswanathan TS and Cushley RJ | Deuterium nuclear magnetic resonance study of the interaction of substrates and inhibitors with soybean lipoxygenase. | 1981 | J. Biol. Chem. | pmid:6788761 |
Jacobsen J and Brodersen R | Albumin-bilirubin binding mechanism. | 1983 | J. Biol. Chem. | pmid:6853485 |
Qureshi N et al. | Monophosphoryl lipid A obtained from lipopolysaccharides of Salmonella minnesota R595. Purification of the dimethyl derivative by high performance liquid chromatography and complete structural determination. | 1985 | J. Biol. Chem. | pmid:3988753 |
Zoeller RA et al. | A possible role for plasmalogens in protecting animal cells against photosensitized killing. | 1988 | J. Biol. Chem. | pmid:3403547 |
Clementz T et al. | Function of the Escherichia coli msbB gene, a multicopy suppressor of htrB knockouts, in the acylation of lipid A. Acylation by MsbB follows laurate incorporation by HtrB. | 1997 | J. Biol. Chem. | pmid:9099672 |
Wong SW et al. | Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner. | 2009 | J. Biol. Chem. | pmid:19648648 |
Helvig C et al. | Suicide inactivation of cytochrome P450 by midchain and terminal acetylenes. A mechanistic study of inactivation of a plant lauric acid omega-hydroxylase. | 1997 | J. Biol. Chem. | pmid:8995277 |
Guengerich FP et al. | Purified liver microsomal cytochrome P-450. Electron-accepting properties and oxidation-reduction potential. | 1975 | J. Biol. Chem. | pmid:1165247 |
Yokotani N et al. | Two forms of omega-hydroxylase toward prostaglandin A and laurate. cDNA cloning and their expression. | 1989 | J. Biol. Chem. | pmid:2600085 |
Boddupalli SS et al. | Fatty acid monooxygenation by cytochrome P-450BM-3. | 1990 | J. Biol. Chem. | pmid:2407733 |
Lee JY et al. | Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4. | 2001 | J. Biol. Chem. | pmid:11278967 |
Lee JY et al. | Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids. | 2003 | J. Biol. Chem. | pmid:12865424 |