lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

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Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Lung Neoplasms D008175 171 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Acne Vulgaris D000152 35 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Thrombosis D013927 49 associated lipids
Prostatic Hyperplasia D011470 20 associated lipids
Brain Infarction D020520 17 associated lipids
Stroke D020521 32 associated lipids
Starvation D013217 47 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Seizures D012640 87 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Cerebral Infarction D002544 6 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Hyperlipidemias D006949 73 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Albuminuria D000419 18 associated lipids
Vasculitis D014657 14 associated lipids
Atherosclerosis D050197 85 associated lipids
Peripheral Arterial Disease D058729 7 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Bird Diseases D001715 4 associated lipids
Obesity, Morbid D009767 8 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Nephrosis, Lipoid D009402 2 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Vascular System Injuries D057772 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

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Authors Title Published Journal PubMed Link
Klevenhusen F et al. Efficiency of monolaurin in mitigating ruminal methanogenesis and modifying C-isotope fractionation when incubating diets composed of either C3 or C4 plants in a rumen simulation technique (Rusitec) system. 2009 Br. J. Nutr. pmid:19505345
Gruffat-Mouty D et al. Effects of dietary coconut oil on apolipoprotein B synthesis and VLDL secretion by calf liver slices. 2001 Br. J. Nutr. pmid:11432760
Jewell C and Cashman KD The effect of conjugated linoleic acid and medium-chain fatty acids on transepithelial calcium transport in human intestinal-like Caco-2 cells. 2003 Br. J. Nutr. pmid:12720584
Pittet PG et al. Site differences in the fatty acid composition of subcutaneous adipose tissue of obese women. 1979 Br. J. Nutr. pmid:486394
Murnaghan MF Effect of fatty acids on the ventricular arrhythmia threshold in the isolated heart of the rabbit. 1981 Br. J. Pharmacol. pmid:7272591
Xu Y et al. Urocortin promotes the development of vasculitis in a rat model of thromboangiitis obliterans via corticotrophin-releasing factor type 1 receptors. 2009 Br. J. Pharmacol. pmid:19572944
Wong KL et al. Dietary cis-fatty acids that increase protein F1 phosphorylation enhance spatial memory. 1989 Brain Res. pmid:2598047
Satoh S et al. Wide therapeutic time window for Rho-kinase inhibition therapy in ischemic brain damage in a rat cerebral thrombosis model. 2008 Brain Res. pmid:18187127
Satoh S et al. Amelioration of endothelial damage/dysfunction is a possible mechanism for the neuroprotective effects of Rho-kinase inhibitors against ischemic brain damage. 2010 Brain Res. Bull. pmid:19723568
Matĕjicek E [Academician Prof. Dr. Karol Siska, M.D., Dr.Sc., bearer of the Order of Work and laureate of the State Prize of the Slovak Socialistic Republic, 65th anniversary]. 1971 Bratisl Lek Listy pmid:4929369
Kravchenko IA et al. Effect of lauric acid on transdermal penetration of phenazepam in vivo. 2003 Bull. Exp. Biol. Med. pmid:15500077
Migliore-Samour D et al. [Immunostimulating and adjuvant activities of a low molecular weight lipopeptide]. 1979 C. R. Acad. Sci., D, Sci. Nat. pmid:117939
MIBASHAN-SHARAGA L [Not Available]. 1949 C. R. Hebd. Seances Acad. Sci. pmid:18118491
Chanussot F and Debry G [Comparison in genetically obese and normal rats in the secretion of lipids synthesized from labeled lauric and oleic acids and glycerol in isolated perfused liver]. 1977 C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. pmid:410533
Chanussot F and Debry G [Comparison in genetically obese and normal rats of the uptake and incorporation of labelled lauric acid, oleic acid, and glycerol by the isolated perfused liver]. 1977 C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. pmid:411584
Demarne Y et al. [Effects of prolonged ingestion of dodecanoic or lauric acid on the secretion of fatty acids in the rat mammary gland]. 1977 C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. pmid:409546
O'Doherty PJ Regulation of ethanolamine and choline phosphatide biosynthesis in isolated rat intestinal villus cells. 1980 Can. J. Biochem. pmid:6449990
Bardi L et al. Esterase activity and release of ethyl esters of medium-chain fatty acids by Saccharomyces cerevisiae during anaerobic growth. 1998 Can. J. Microbiol. pmid:10347863
Saheb SA et al. [Effect of fatty acids on the antibacterial activity of butylated hydroxytoluene (BHT)]. 1978 Can. J. Microbiol. pmid:743642
Yang J et al. Anti-Escherichia coli O157:H7 activity of free fatty acids under varying pH. 2010 Can. J. Microbiol. pmid:20453913
Hotke C et al. Jejunal uptake of sugars, cholesterol, fatty acids, and fatty alcohols in vivo in diabetic rats. 1985 Can. J. Physiol. Pharmacol. pmid:4075254
Amtmann E and Sauer G Selective killing of tumor cells by xanthates. 1987 Cancer Lett. pmid:3594421
Sauer G et al. Systemic treatment of a human epidermoid non-small cell lung carcinoma xenograft with a xanthate compound causes extensive intratumoral necrosis. 1990 Cancer Lett. pmid:2170004
Tinsley IJ et al. Influence of dietary fatty acids on the incidence of mammary tumors in the C3H mouse. 1981 Cancer Res. pmid:7214328
Conway JG et al. Role of fatty acyl coenzyme A oxidase in the efflux of oxidized glutathione from perfused livers of rats treated with the peroxisome proliferator nafenopin. 1987 Cancer Res. pmid:3621175
Udomrati S and Gohtani S Enzymatic esterification of tapioca maltodextrin fatty acid ester. 2014 Carbohydr Polym pmid:24274521
Kupetz M et al. Impact of flavouring substances on the aggregation behaviour of dissolved barley β-glucans in a model beer. 2016 Carbohydr Polym pmid:27083361
Cerchiara T et al. Microparticles based on chitosan/carboxymethylcellulose polyelectrolyte complexes for colon delivery of vancomycin. 2016 Carbohydr Polym pmid:27083351
Zhang W et al. Enhanced physicochemical properties of chitosan/whey protein isolate composite film by sodium laurate-modified TiO2 nanoparticles. 2016 Carbohydr Polym pmid:26794738
Modolon Sde M et al. Self-association of sodium deoxycholate with EHEC cellulose cooperatively induced by sodium dodecanoate. 2014 Carbohydr Polym pmid:25037371
Winkler H et al. Synthesis and properties of fatty acid starch esters. 2013 Carbohydr Polym pmid:23987337
Choudhury B et al. The structure of the L9 immunotype lipooligosaccharide from Neisseria meningitidis NMA Z2491. 2008 Carbohydr. Res. pmid:18804756
Peng F et al. Rapid homogeneous lauroylation of wheat straw hemicelluloses under mild conditions. 2008 Carbohydr. Res. pmid:18793765
Mazeau K et al. Conformational analysis of xylan chains. 2005 Carbohydr. Res. pmid:16288999
Tai A et al. Regioselective monoacylation of 2-O-α-D-glucopyranosyl-L-ascorbic acid by a polymer catalyst in N,N-dimethylformamide. 2011 Carbohydr. Res. pmid:21903204
Aarsaether N et al. Changes in peroxisomes and mitochondria in liver of ethionine exposed rats: a biochemical and morphological investigation. 1989 Carcinogenesis pmid:2498002
Khan S et al. Effect of a Prudhoe Bay crude oil on hepatic and renal peroxisomal beta-oxidation and mixed-function oxidase activities in rats. 1989 Carcinogenesis pmid:2912577
Hayes ML Reduction in acid tolerance of Streptococcus downeii by fluoride and potassium laurate. 1994 Caries Res. pmid:8156568
Thibaut R et al. Assessment of metabolic capabilities of PLHC-1 and RTL-W1 fish liver cell lines. 2009 Cell Biol. Toxicol. pmid:19142739
Nordström T et al. Inhibition of CD3-induced Ca2+ signals in Jurkat T-cells by myristic acid. 1991 Cell Calcium pmid:1834341
Ramírez-Agudelo ME et al. Fatty acid profile during the differentiation and infection with Mycobacterium tuberculosis of mononuclear phagocytes of patients with TB and healthy individuals. 2011 Cell. Immunol. pmid:21571261
Bainbridge BW et al. Expression of a Porphyromonas gingivalis lipid A palmitylacyltransferase in Escherichia coli yields a chimeric lipid A with altered ability to stimulate interleukin-8 secretion. 2006 Cell. Microbiol. pmid:16367871
Starha L and Chalabala M [Oral long-acting drugs. 8. Effects of palmitic and lauric acid and their glycerine esters on the slowing of the drug release]. 1972 Cesk Farm pmid:5075740
Siano A et al. Interaction of acylated and substituted antimicrobial peptide analogs with phospholipid-polydiacetylene vesicles. Correlation with their biological properties. 2011 Chem Biol Drug Des pmid:21496212
Lv GP et al. Comparison of sterols and fatty acids in two species of Ganoderma. 2012 Chem Cent J pmid:22293530
Liu J et al. Anti-androgenic activity of fatty acids. 2009 Chem. Biodivers. pmid:19353546
El Ayeb-Zakhama A et al. Chemical composition and allelopathic potential of essential oils obtained from Acacia cyanophylla Lindl. Cultivated in Tunisia. 2015 Chem. Biodivers. pmid:25879505
Cecotti R et al. Determination of the volatile fraction of Polygonum bistorta L. at different growing stages and evaluation of its antimicrobial activity against two major honeybee (Apis mellifera) pathogens. 2012 Chem. Biodivers. pmid:22344911
Salles HC et al. The venomous secrets of the web droplets from the viscid spiral of the orb-weaver spider Nephila clavipes (Araneae, Tetragnatidae). 2006 Chem. Biodivers. pmid:17193305
Blazević I et al. Hedge mustard (Sisymbrium officinale): chemical diversity of volatiles and their antimicrobial activity. 2010 Chem. Biodivers. pmid:20730965
Mo S et al. Elucidation of the Streptomyces coelicolor pathway to 2-undecylpyrrole, a key intermediate in undecylprodiginine and streptorubin B biosynthesis. 2008 Chem. Biol. pmid:18291318
Marynka K et al. In vitro discriminative antipseudomonal properties resulting from acyl substitution of N-terminal sequence of dermaseptin s4 derivatives. 2007 Chem. Biol. pmid:17254954
Sun CQ et al. The antimicrobial properties of milkfat after partial hydrolysis by calf pregastric lipase. 2002 Chem. Biol. Interact. pmid:12076524
Bacher MA and Gibson GG Chlorophenoxyacid herbicides induce microsomal cytochrome P-450 IVA1 (P-452) in rat liver. 1988 Chem. Biol. Interact. pmid:3365825
Charest-Boule L et al. Influence of free fatty acid anion on the binding of warfarin to cytoplasmic proteins from rat liver. 1980 Chem. Biol. Interact. pmid:7356538
Weinkam RJ et al. Protein mediated chemical reactions of chloroethylnitrosoureas. 1980 Chem. Biol. Interact. pmid:7389008
Guan X et al. Cytochrome P450-dependent desaturation of lauric acid: isoform selectivity and mechanism of formation of 11-dodecenoic acid. 1998 Chem. Biol. Interact. pmid:9566728
Staab CA et al. Medium-chain fatty acids and glutathione derivatives as inhibitors of S-nitrosoglutathione reduction mediated by alcohol dehydrogenase 3. 2009 Chem. Biol. Interact. pmid:19428350
Tran NH et al. Light-initiated hydroxylation of lauric acid using hybrid P450 BM3 enzymes. 2011 Chem. Commun. (Camb.) pmid:21975564
Weissenborn MJ et al. Whole-cell microtiter plate screening assay for terminal hydroxylation of fatty acids by P450s. 2016 Chem. Commun. (Camb.) pmid:27074906
Ribot F et al. In situ evaluation of interfacial affinity in CeO2 based hybrid nanoparticles by pulsed field gradient NMR. 2005 Chem. Commun. (Camb.) pmid:15719102
Uchida T et al. Preparation and characterization of insulin-loaded acrylic hydrogels containing absorption enhancers. 2001 Chem. Pharm. Bull. pmid:11605651
de Regil-Hernández R et al. New green synthesis and formulations of acyclovir prodrugs. 2011 Chem. Pharm. Bull. pmid:21881250
Liu CH and Huang HY In vitro anti-propionibacterium activity by curcumin containing vesicle system. 2013 Chem. Pharm. Bull. pmid:23546001
Kamachi S et al. Spectrophotometric assay for lipase in serum using a chromogenic substrate, Orange I laurate. 1983 Chem. Pharm. Bull. pmid:6652817
Ogiso T et al. Enhancement effect of lauric acid on the rectal absorption of propranolol from suppository in rats. 1991 Chem. Pharm. Bull. pmid:1806286
Watanabe T et al. Co-suppression by nicardipine, a calcium antagonist, of induction of microsomal lauric acid hydroxylation with peroxisome proliferation in clofibrate-treated rat liver. 1991 Chem. Pharm. Bull. pmid:1914008
Iwahashi M et al. Dynamical dimer structure and liquid structure of fatty acids in their binary liquid mixture: dodecanoic and 3-phenylpropionic acids system. 2004 Chem. Phys. Lipids pmid:15081860
Inoue T et al. Solid-liquid phase behavior of binary fatty acid mixtures. 2. Mixtures of oleic acid with lauric acid, myristic acid, and palmitic acid. 2004 Chem. Phys. Lipids pmid:14725999
Fauconnot L et al. Chemical synthesis and NMR characterization of structured polyunsaturated triacylglycerols. 2006 Chem. Phys. Lipids pmid:16405879
Costa MC et al. The solid-liquid phase diagrams of binary mixtures of consecutive, even saturated fatty acids. 2009 Chem. Phys. Lipids pmid:19520067
Chaleepa K et al. Effect of additives on isothermal crystallization kinetics and physical characteristics of coconut oil. 2010 Chem. Phys. Lipids pmid:20346930
Mirsky VM Effect of the lipid hydrolysis products on the phospholipase A2 action towards lipid monolayer. 1994 Chem. Phys. Lipids pmid:8013058
Iwahashi M et al. Dynamical dimer structure and liquid structure of fatty acids in their binary liquid mixture: decanoic/octadecanoic acid and decanoic/dodecanoic acid systems. 2005 Chem. Phys. Lipids pmid:15642581
Grillo MP and Hua F Enantioselective formation of ibuprofen-S-acyl-glutathione in vitro in incubations of ibuprofen with rat hepatocytes. 2008 Chem. Res. Toxicol. pmid:18680316
Clarke SE et al. Lauric acid as a model substrate for the simultaneous determination of cytochrome P450 2E1 and 4A in hepatic microsomes. 1994 Nov-Dec Chem. Res. Toxicol. pmid:7696540
Barham P et al. Molecular gastronomy: a new emerging scientific discipline. 2010 Chem. Rev. pmid:20170128
Mattes RD Oral thresholds and suprathreshold intensity ratings for free fatty acids on 3 tongue sites in humans: implications for transduction mechanisms. 2009 Chem. Senses pmid:19357229
Su Z et al. Rates of fatty acid oxidations by P450 compound I are pH dependent. 2012 Chembiochem pmid:22890798
Wu B et al. Broad hexagonal columnar mesophases formation in bioinspired transition-metal complexes of simple fatty acid meta-octaester derivatives of meso-tetraphenyl porphyrins. 2015 Chemistry pmid:25619819
Si S et al. In situ synthesis of gold and silver nanoparticles by using redox-active amphiphiles and their phase transfer to organic solvents. 2007 Chemistry pmid:17960550
Coll C et al. Fatty acid carboxylate- and anionic surfactant-controlled delivery systems that use mesoporous silica supports. 2010 Chemistry pmid:20645326
Fauser JK et al. Induction of apoptosis by the medium-chain length fatty acid lauric acid in colon cancer cells due to induction of oxidative stress. 2013 Chemotherapy pmid:24356281
Fu J et al. Hydrothermal decarboxylation and hydrogenation of fatty acids over Pt/C. 2011 ChemSusChem pmid:21275064
Chen Y et al. [A new rat model of cerebral infarction based on the injury of vascular endothelial cell]. 2005 Chin J Integr Med pmid:16181534
Scholl J Traditional dietary recommendations for the prevention of cardiovascular disease: do they meet the needs of our patients? 2012 Cholesterol pmid:22482040
Jiang M et al. Smooth muscle--specific expression of CYP4A1 induces endothelial sprouting in renal arterial microvessels. 2004 Circ. Res. pmid:14670847
Fleming I Cytochrome P-450 under pressure: more evidence for a link between 20-hydroxyeicosatetraenoic acid and hypertension. 2005 Circulation pmid:15630035
Gainer JV et al. Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension. 2005 Circulation pmid:15611369
Reginster JY et al. Estradiol pharmacokinetics after transdermal application of patches to postmenopausal women: matrix versus reservoir patches. 2000 Climacteric pmid:11910618
Payne CM et al. Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis. 2011 Clin Exp Gastroenterol pmid:21753893
Jicha GA and Markesbery WR Omega-3 fatty acids: potential role in the management of early Alzheimer's disease. 2010 Clin Interv Aging pmid:20396634
Chan J et al. Effect of water-in-oil microemulsions and lamellar liquid crystalline systems on the precorneal tear film of albino New Zealand rabbits. 2008 Clin Ophthalmol pmid:19668396
Campagnoli M et al. Structural analysis, fatty acid and thyroxine binding properties of Vancouver and Naskapi variants of human serum albumin. 2003 Clin. Biochem. pmid:14636873
Poudrier J et al. Influence of dendritic cells on B-cell responses during HIV infection. 2012 Clin. Dev. Immunol. pmid:22461837
Pandey SK et al. A tribute to Charles David Kelman MD: ophthalmologist, inventor and pioneer of phacoemulsification surgery. 2004 Clin. Experiment. Ophthalmol. pmid:15498067
Haim A et al. Patellofemoral pain syndrome: validity of clinical and radiological features. 2006 Clin. Orthop. Relat. Res. pmid:16788411
Edirisinghe I et al. Effect of fatty acids on endothelium-dependent relaxation in the rabbit aorta. 2006 Clin. Sci. pmid:16524362
Marie SK and Shinjo SM Metabolism and brain cancer. 2011 Clinics (Sao Paulo) pmid:21779721
Kim YJ et al. Combination of nanoparticles with photothermal effects and phase-change material enhances the non-invasive transdermal delivery of drugs. 2015 Colloids Surf B Biointerfaces pmid:26277712