lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

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Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Lung Neoplasms D008175 171 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Acne Vulgaris D000152 35 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Thrombosis D013927 49 associated lipids
Prostatic Hyperplasia D011470 20 associated lipids
Brain Infarction D020520 17 associated lipids
Stroke D020521 32 associated lipids
Starvation D013217 47 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Seizures D012640 87 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Cerebral Infarction D002544 6 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Hyperlipidemias D006949 73 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Albuminuria D000419 18 associated lipids
Vasculitis D014657 14 associated lipids
Atherosclerosis D050197 85 associated lipids
Peripheral Arterial Disease D058729 7 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Bird Diseases D001715 4 associated lipids
Obesity, Morbid D009767 8 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Nephrosis, Lipoid D009402 2 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Vascular System Injuries D057772 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

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Per page 10 20 50 100 | Total 1837
Authors Title Published Journal PubMed Link
Christensen E et al. Beta-oxidation of medium chain (C8-C14) fatty acids studied in isolated liver cells. 1989 Biochim. Biophys. Acta pmid:2752017
Wada M et al. Mechanism of biosynthesis of unsaturated fatty acids in Pseudomonas sp. strain E-3, a psychrotrophic bacterium. 1989 J. Bacteriol. pmid:2753856
Ryals PE et al. Lipid modification during cytodifferentiation of Tetrahymena vorax. Whole cell phospholipids and triacylglycerols of microstomal and macrostomal phenotypes. 1989 Biochim. Biophys. Acta pmid:2730920
Miranda CL et al. Purification and characterization of hepatic steroid hydroxylases from untreated rainbow trout. 1989 Arch. Biochem. Biophys. pmid:2536262
Imai Y et al. Structure-function relationships of cytochrome P-450 laurate (omega-1)-hydroxylase. 1989 Drug Metab. Rev. pmid:2680391
Graham SA Cuphea: a new plant source of medium-chain fatty acids. 1989 Crit Rev Food Sci Nutr pmid:2653730
Mishima M et al. Promotion of nasal absorption of insulin by glycyrrhetinic acid derivatives. I. 1989 J. Pharmacobio-dyn. pmid:2656985
Morisaki H [Inhibition of neutrophil function by solvent of injectable sedatives--effects of propylene glycol, ethanol and benzyl alcohol]. 1989 Masui pmid:2614886
Kocarek TA and Feller DR Quantitative assessment of enzyme induction by peroxisome proliferators and application to determination of effects on triglyceride biosynthesis in primary cultures of rat hepatocytes. 1989 Biochem. Pharmacol. pmid:2597188
Fibach E et al. Analysis of cellular heterogeneity in the response of human leukemic cells to photosensitization induced by pyrene-containing fatty acid. 1989 Leuk. Res. pmid:2559259
Yokotani N et al. Two forms of omega-hydroxylase toward prostaglandin A and laurate. cDNA cloning and their expression. 1989 J. Biol. Chem. pmid:2600085
Khodari M et al. Applications in drug analysis of carbon paste electrodes modified by fatty acids. 1989 J Pharm Biomed Anal pmid:2490534
Imai Y and Nakamura M Point mutations at threonine-301 modify substrate specificity of rabbit liver microsomal cytochromes P-450 (laurate (omega-1)-hydroxylase and testosterone 16 alpha-hydroxylase). 1989 Biochem. Biophys. Res. Commun. pmid:2493247
Borlakoglu JT et al. Evidence for the induction of cytochrome P-452 in rat liver by Aroclor 1254, a commercial mixture of polychlorinated biphenyls. 1989 FEBS Lett. pmid:2497034
Aarsaether N et al. Changes in peroxisomes and mitochondria in liver of ethionine exposed rats: a biochemical and morphological investigation. 1989 Carcinogenesis pmid:2498002
Green PG et al. Enhanced in vitro skin permeation of cationic drugs. 1989 Pharm. Res. pmid:2798314
Ohhira S and Matsui H [Determination of dibutyltin compounds in polyvinyl chloride resin by capillary gas chromatography]. 1989 Nihon Eiseigaku Zasshi pmid:2746975
Stucki JW et al. Acylation of proteins by myristic acid in isolated mitochondria. 1989 J. Biol. Chem. pmid:2703494
Bugaut M In vivo incorporation of lauric acid into rat adipose tissue triacylglycerols. 1989 Lipids pmid:2761351
Leakey JE et al. Effects of aging and caloric restriction on hepatic drug metabolizing enzymes in the Fischer 344 rat. I: The cytochrome P-450 dependent monooxygenase system. 1989 Mech. Ageing Dev. pmid:2661932
Sanglard D and Loper JC Characterization of the alkane-inducible cytochrome P450 (P450alk) gene from the yeast Candida tropicalis: identification of a new P450 gene family. 1989 Gene pmid:2663647
Frolov AF et al. Fatty acid composition of lipopolysaccharides of the strains of different species of Yersinia. 1989 J Hyg Epidemiol Microbiol Immunol pmid:2723424
Menke G et al. Kinetics of drug binding to human serum albumin: allosteric and competitive inhibition at the benzodiazepine binding site by free fatty acids of various chain lengths. 1989 Jan-Feb Naunyn Schmiedebergs Arch. Pharmacol. pmid:2471088
Yamazaki M et al. The effect of fatty acids on the rectal absorption of acyclovir in rats. 1990 J. Pharm. Pharmacol. pmid:1979629
Radom J et al. Influence of chain length of pyrene fatty acids on their uptake and metabolism by Epstein-Barr-virus-transformed lymphoid cell lines from a patient with multisystemic lipid storage myopathy and from control subjects. 1990 Biochem. J. pmid:2165389
Ogiso T and Shintani M Mechanism for the enhancement effect of fatty acids on the percutaneous absorption of propranolol. 1990 J Pharm Sci pmid:2079652
Bergman T and Postlind H Characterization of pig kidney microsomal cytochrome P-450 catalysing 25-hydroxylation of vitamin D3 and C27 steroids. 1990 Biochem. J. pmid:2169238
Sauer G et al. Systemic treatment of a human epidermoid non-small cell lung carcinoma xenograft with a xanthate compound causes extensive intratumoral necrosis. 1990 Cancer Lett. pmid:2170004
Pedersen AO et al. Thermodynamic parameters for binding of fatty acids to human serum albumin. 1990 Eur. J. Biochem. pmid:2373077
Mensink RP and Katan MB Effect of dietary trans fatty acids on high-density and low-density lipoprotein cholesterol levels in healthy subjects. 1990 N. Engl. J. Med. pmid:2374566
Hickey AJ et al. Effect of hydrophobic coating on the behavior of a hygroscopic aerosol powder in an environment of controlled temperature and relative humidity. 1990 J Pharm Sci pmid:2292762
Aoyama T et al. Clofibrate-inducible rat hepatic P450s IVA1 and IVA3 catalyze the omega- and (omega-1)-hydroxylation of fatty acids and the omega-hydroxylation of prostaglandins E1 and F2 alpha. 1990 J. Lipid Res. pmid:2280187
Boddupalli SS et al. Fatty acid monooxygenation by cytochrome P-450BM-3. 1990 J. Biol. Chem. pmid:2407733
Brozek KA and Raetz CR Biosynthesis of lipid A in Escherichia coli. Acyl carrier protein-dependent incorporation of laurate and myristate. 1990 J. Biol. Chem. pmid:2203778
Miranda CL et al. Regiospecificity in the hydroxylation of lauric acid by rainbow trout hepatic cytochrome P450 isozymes. 1990 Biochem. Biophys. Res. Commun. pmid:2403346
Nakamura J et al. Effect of straight chain fatty acids on seizures induced by picrotoxin and pentylenetetrazole in mice. 1990 J. Pharmacobio-dyn. pmid:2341972
Bergeron N et al. Interaction between dietary proteins and lipids in the regulation of serum and liver lipids in the rabbit. Effect of fish protein. 1991 Lipids pmid:1762524
Hare WR and Wahle KW The participation of soluble factors in the omega-oxidation of fatty acids in the liver of the sheep. 1991 Lipids pmid:2051891
Giera DD and van Lier RB A convenient method for the determination of hepatic lauric acid omega-oxidation based on solvent partition. 1991 Fundam Appl Toxicol pmid:2055365
Nordström T et al. Inhibition of CD3-induced Ca2+ signals in Jurkat T-cells by myristic acid. 1991 Cell Calcium pmid:1834341
Ogiso T et al. Enhancement effect of lauric acid on the rectal absorption of propranolol from suppository in rats. 1991 Chem. Pharm. Bull. pmid:1806286
Watanabe T et al. Co-suppression by nicardipine, a calcium antagonist, of induction of microsomal lauric acid hydroxylation with peroxisome proliferation in clofibrate-treated rat liver. 1991 Chem. Pharm. Bull. pmid:1914008
Hara H et al. Effect of (+/-)-2-(dimethylamino)-1-[[o-(m-methoxyphenethyl)phenoxy] methyl]ethyl hydrogen succinate on experimental models of peripheral obstructive disease. 1991 Arzneimittelforschung pmid:1930349
Swinney DC et al. A novel rat hepatic clofibrate-inducible cytochrome P450 that is not a lauric acid hydroxylase. 1991 Biochem. Pharmacol. pmid:1662512
Ogiso T et al. Enhancement by fatty acids of the rectal absorption of propranolol: in vitro evaluation in the rat. 1991 J. Pharmacobio-dyn. pmid:1802986
Yamada J et al. Assay of fatty acid omega-hydroxylation using high-performance liquid chromatography with fluorescence labeling reagent, 3-bromomethyl-7-methoxy-1,4-benzoxazin-2-one (BrMB). 1991 Anal. Biochem. pmid:1839651
Dirven HA et al. Determination of the cytochrome P-450 IV marker, omega-hydroxylauric acid, by high-performance liquid chromatography and fluorimetric detection. 1991 J. Chromatogr. pmid:1860919
Maurich V et al. p-nitrophenyllaurate: a substrate for the high-performance liquid chromatographic determination of lipase activity. 1991 J. Chromatogr. pmid:1939456
Salerno JW and Smith DE The use of sesame oil and other vegetable oils in the inhibition of human colon cancer growth in vitro. 1991 Jan-Feb Anticancer Res. pmid:2018355
Hvattum E et al. Microsomal oxidation of dodecylthioacetic acid (a 3-thia fatty acid) in rat liver. 1991 Mar 15-Apr 1 Biochem. Pharmacol. pmid:1672593