| MeSH term | MeSH ID | Detail |
|---|---|---|
| Seizures | D012640 | 87 associated lipids |
| Prostatic Hyperplasia | D011470 | 20 associated lipids |
| Obesity, Morbid | D009767 | 8 associated lipids |
| Nephrosis, Lipoid | D009402 | 2 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Malabsorption Syndromes | D008286 | 16 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Liver Diseases, Alcoholic | D008108 | 13 associated lipids |
| Leukemia, Myeloid | D007951 | 52 associated lipids |
lauric acid
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
Cross Reference
Introduction
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with lauric acid?
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with lauric acid
PubChem Associated disorders and diseases
What pathways are associated with lauric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with lauric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with lauric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with lauric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with lauric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with lauric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with lauric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Amet Y et al. | Validation of the (omega-1)-hydroxylation of lauric acid as an in vitro substrate probe for human liver CYP2E1. | 1995 | Biochem. Pharmacol. | pmid:8615855 |
| Williams DE et al. | Sex differences in cytochrome P-450 isozyme composition and activity in kidney microsomes of mature rainbow trout. | 1986 | Biochem. Pharmacol. | pmid:3718543 |
| Pons N et al. | Interaction of polyhalogenated compounds of appropriate configuration with mammalian or bacterial CYP enzymes. Increased bilirubin and uroporphyrinogen oxidation in vitro. | 2003 | Biochem. Pharmacol. | pmid:12907239 |
| Kikuta Y et al. | Expression and induction of cytochrome P450s in rabbit parotid glands. | 2001 | Biochem. Pharmacol. | pmid:11389885 |
| Kocarek TA and Feller DR | Induction of peroxisomal fatty acyl-CoA oxidase and microsomal laurate hydroxylase activities by beclobric acid and two metabolites in primary cultures of rat hepatocytes. | 1987 | Biochem. Pharmacol. | pmid:3632723 |
| De Matteis F et al. | Peroxidase-like activity of uncoupled cytochrome P450: studies with bilirubin and toxicological implications of uncoupling. | 2012 | Biochem. Pharmacol. | pmid:22564776 |
| Knickle LC et al. | The suppression of hepatic cytochrome P4504A mRNA mediated by the interferon inducer polyinosinic acid.polycytidylic acid. | 1992 | Biochem. Pharmacol. | pmid:1380810 |
| RodrÃguez-Penas D et al. | Aliskiren affects fatty-acid uptake and lipid-related genes in rodent and human cardiomyocytes. | 2011 | Biochem. Pharmacol. | pmid:21640714 |
| Sivapathasundaram S et al. | A study of the expression of the xenobiotic-metabolising cytochrome P450 proteins and of testosterone metabolism in bovine liver. | 2001 | Biochem. Pharmacol. | pmid:11585060 |
| Amet Y et al. | Cytochrome P450 4A and 2E1 expression in human kidney microsomes. | 1997 | Biochem. Pharmacol. | pmid:9113097 |
| Okita RT et al. | Lauric acid hydroxylation in human liver and kidney cortex microsomes. | 1979 | Biochem. Pharmacol. | pmid:533546 |
| Imaoka S et al. | Mutagenic activation of urinary bladder carcinogens by CYP4B1 and the presence of CYP4B1 in bladder mucosa. | 1997 | Biochem. Pharmacol. | pmid:9310344 |
| Hvattum E et al. | Microsomal oxidation of dodecylthioacetic acid (a 3-thia fatty acid) in rat liver. | 1991 Mar 15-Apr 1 | Biochem. Pharmacol. | pmid:1672593 |
| Sharma RK et al. | Role of hepatic and renal cytochrome P-450 IVA1 in the metabolism of lipid substrates. | 1989 | Biochem. Pharmacol. | pmid:2554928 |
| Kitagawa S et al. | Effects of alkyl gallates on P-glycoprotein function. | 2005 | Biochem. Pharmacol. | pmid:16139251 |
| Pham MA et al. | Characterization of distinct forms of cytochromes P-450, epoxide metabolizing enzymes and UDP-glucuronosyltransferases in rat skin. | 1989 | Biochem. Pharmacol. | pmid:2500129 |
| Swinney DC et al. | A novel rat hepatic clofibrate-inducible cytochrome P450 that is not a lauric acid hydroxylase. | 1991 | Biochem. Pharmacol. | pmid:1662512 |
| Lundgren B et al. | Effects of dietary treatment with 11 dicarboxylic acids, diethylcarboxylic esters and fatty acids on peroxisomal fatty acid beta-oxidation, epoxide hydrolases and lauric acid omega-hydroxylation in mouse liver. | 1992 | Biochem. Pharmacol. | pmid:1540233 |
| Thomas H et al. | Effect of hypolipidemic compounds on lauric acid hydroxylation and phase II enzymes. | 1989 | Biochem. Pharmacol. | pmid:2500933 |
| Nakamura M et al. | Induction of cytochrome P450 isozymes in rat renal microsomes by cyclosporin A. | 1994 | Biochem. Pharmacol. | pmid:7980643 |