lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

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Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Seizures D012640 87 associated lipids
Prostatic Hyperplasia D011470 20 associated lipids
Obesity, Morbid D009767 8 associated lipids
Nephrosis, Lipoid D009402 2 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Lung Neoplasms D008175 171 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Per page 10 20 50 | Total 33

PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

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Per page 10 20 50 100 | Total 1837
Authors Title Published Journal PubMed Link
Past MR and Cook DE Effect of diabetes on rat liver cytochrome P-450. Evidence for a unique diabetes-dependent rat liver cytochrome P-450. 1982 Biochem. Pharmacol. pmid:7150359
Kocarek TA and Feller DR Induction of peroxisomal fatty acyl-CoA oxidase and microsomal laurate hydroxylase activities by beclobric acid and two metabolites in primary cultures of rat hepatocytes. 1987 Biochem. Pharmacol. pmid:3632723
Knickle LC et al. The suppression of hepatic cytochrome P4504A mRNA mediated by the interferon inducer polyinosinic acid.polycytidylic acid. 1992 Biochem. Pharmacol. pmid:1380810
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Raza H and Levine WG Effect of hypolipidemic drugs on the metabolism of lauric acid and dimethylaminoazobenzene by rat liver microsomes. 1987 Biochem. Pharmacol. pmid:3103631
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Gibson GG and Bains SK Cytochrome P-450 isoenzymes involved in fatty acid metabolism. 1985 Biochem. Soc. Trans. pmid:4065418
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Abigor RD et al. Lipase-catalysed production of biodiesel fuel from some Nigerian lauric oils. 2000 Biochem. Soc. Trans. pmid:11171279
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Ost TW et al. Phenylalanine 393 exerts thermodynamic control over the heme of flavocytochrome P450 BM3. 2001 Biochemistry pmid:11695888
CaJacob CA and Ortiz de Montellano PR Mechanism-based in vivo inactivation of lauric acid hydroxylases. 1986 Biochemistry pmid:3490272
Modi S et al. NMR studies of substrate binding to cytochrome P450 BM3: comparisons to cytochrome P450 cam. 1995 Biochemistry pmid:7619797
Gasymov OK et al. Ligand binding site of tear lipocalin: contribution of a trigonal cluster of charged residues probed by 8-anilino-1-naphthalenesulfonic acid. 2008 Biochemistry pmid:18179255
Murataliev MB et al. Functional interactions in cytochrome P450BM3: flavin semiquinone intermediates, role of NADP(H), and mechanism of electron transfer by the flavoprotein domain. 1997 Biochemistry pmid:9204888
Zheng YM et al. Identification of a meander region proline residue critical for heme binding to cytochrome P450: implications for the catalytic function of human CYP4B1. 1998 Biochemistry pmid:9737862
Davis JH 2H nuclear magnetic resonance of exchange-labeled gramicidin in an oriented lyotropic nematic phase. 1988 Biochemistry pmid:2450569
Echtay KS et al. Role of intrahelical arginine residues in functional properties of uncoupling protein (UCP1). 2001 Biochemistry pmid:11318647