lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

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Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Obesity, Morbid D009767 8 associated lipids
Prostatic Hyperplasia D011470 20 associated lipids
Seizures D012640 87 associated lipids
Starvation D013217 47 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Thrombosis D013927 49 associated lipids
Vasculitis D014657 14 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Brain Infarction D020520 17 associated lipids
Stroke D020521 32 associated lipids
Atherosclerosis D050197 85 associated lipids
Vascular System Injuries D057772 2 associated lipids
Peripheral Arterial Disease D058729 7 associated lipids
Per page 10 20 50 | Total 33

PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

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Per page 10 20 50 100 | Total 1837
Authors Title Published Journal PubMed Link
Lee CK et al. Relationship between lipophilicity and skin permeability of various drugs from an ethanol/water/lauric acid system. 1994 Biol. Pharm. Bull. pmid:7874070
Komata Y et al. Effect of fatty acid on the accumulation of thiamine disulfide in rat skin. 1994 Biol. Pharm. Bull. pmid:7920438
Amet Y et al. Evidence that cytochrome P450 2E1 is involved in the (omega-1)-hydroxylation of lauric acid in rat liver microsomes. 1994 Biochem. Biophys. Res. Commun. pmid:8093035
Duncan T et al. A glycoprotein binding retinoids and fatty acids is present in Drosophila. 1994 Arch. Biochem. Biophys. pmid:8031123
Keegan FP and Blum JJ Incorporation of label from acetate and laurate into the mannan of Leishmania donovani via the glyoxylate cycle. 1993 Nov-Dec J. Eukaryot. Microbiol. pmid:7904877
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Imaoka S et al. Identification of CYP2C23 expressed in rat kidney as an arachidonic acid epoxygenase. 1993 J. Pharmacol. Exp. Ther. pmid:8246128
Carlson GP Formation of fatty acid propyl esters in liver, lung and pancreas of rats administered 1-propanol. 1993 Res. Commun. Chem. Pathol. Pharmacol. pmid:8210685
Tenma T et al. Development of new lipophilic derivatives of tetragastrin: physicochemical characteristics and intestinal absorption of acyl-tetragastrin derivatives in rats. 1993 Pharm. Res. pmid:8272412
Straub P et al. Hydrophobic side chain requirements for lauric acid and progesterone hydroxylation at amino acid 113 in cytochrome P450 2C2, a potential determinant of substrate specificity. 1993 Arch. Biochem. Biophys. pmid:8215458
Miwa T et al. Modulation of morphine action by lauric acid. 1993 Biol. Pharm. Bull. pmid:8220329
Smith SW and Anderson BD Salt and mesophase formation in aqueous suspensions of lauric acid. 1993 Pharm. Res. pmid:8272419
Orlowski M et al. Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids. 1993 Biochemistry pmid:8431436
Goldberg ML and Enig MG Palmitic and lauric acids and serum cholesterol. 1993 Am. J. Clin. Nutr. pmid:8338054
Mustranta A et al. Applications of immobilized lipases to transesterification and esterification reactions in nonaqueous systems. 1993 Enzyme Microb. Technol. pmid:7763454
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Knickle LC et al. The suppression of hepatic cytochrome P4504A mRNA mediated by the interferon inducer polyinosinic acid.polycytidylic acid. 1992 Biochem. Pharmacol. pmid:1380810
Denke MA and Grundy SM Comparison of effects of lauric acid and palmitic acid on plasma lipids and lipoproteins. 1992 Am. J. Clin. Nutr. pmid:1415008
Sohlenius AK et al. The effects of perfluoro-octanoic acid on hepatic peroxisome proliferation and related parameters show no sex-related differences in mice. 1992 Biochem. J. pmid:1497616
Ng TK et al. Dietary palmitic and oleic acids exert similar effects on serum cholesterol and lipoprotein profiles in normocholesterolemic men and women. 1992 J Am Coll Nutr pmid:1506599
Himejima M and Kubo I Antimicrobial agents from Licaria puchuri-major and their synergistic effect with polygodial. 1992 J. Nat. Prod. pmid:1517735
Miko M and Devínsky F Biochemical basis of cytotoxic activity of some new N'-oxides of N',N'-dimethylaminoalkylamides of dodecanoic acid. 1992 Drug Metabol Drug Interact pmid:1424644
Lemaire P et al. Subterminal hydroxylation of lauric acid by microsomes from a marine fish. 1992 Lipids pmid:1522763
Jin SJ et al. Incomplete fatty acid oxidation. The production and epimerization of 3-hydroxy fatty acids. 1992 J. Biol. Chem. pmid:1730577
Salaün JP et al. Stereochemistry of oxidized fatty acids generated during catalytic oxygenation of lauric acid and unsaturated analogs by plant microsomes. 1992 FEBS Lett. pmid:1607005
Garfinkel M et al. Insulinotropic potency of lauric acid: a metabolic rationale for medium chain fatty acids (MCF) in TPN formulation. 1992 J. Surg. Res. pmid:1593871
Okita RT and Okita JR Characterization of a cytochrome P450 from di(2-ethylhexyl) phthalate-treated rats which hydroxylates fatty acids. 1992 Arch. Biochem. Biophys. pmid:1567203
Adachi H et al. Inhibitory effect of prostaglandin E1 on laurate-induced peripheral vascular occlusive sequelae in rabbits: optimized topical formulation with beta-cyclodextrin derivative and penetration enhancer HPE-101. 1992 J. Pharm. Pharmacol. pmid:1361553
Komata Y et al. In vitro percutaneous absorption of thiamine disulfide from a mixture of propylene glycol and fatty acid. 1992 J Pharm Sci pmid:1403716
Lundgren B et al. Effects of dietary treatment with 11 dicarboxylic acids, diethylcarboxylic esters and fatty acids on peroxisomal fatty acid beta-oxidation, epoxide hydrolases and lauric acid omega-hydroxylation in mouse liver. 1992 Biochem. Pharmacol. pmid:1540233
Blum JJ Effects of osmotic pressure on the oxidative metabolism of Leishmania major promastigotes. 1991 May-Jun J. Protozool. pmid:1679134
Hvattum E et al. Microsomal oxidation of dodecylthioacetic acid (a 3-thia fatty acid) in rat liver. 1991 Mar 15-Apr 1 Biochem. Pharmacol. pmid:1672593
Salerno JW and Smith DE The use of sesame oil and other vegetable oils in the inhibition of human colon cancer growth in vitro. 1991 Jan-Feb Anticancer Res. pmid:2018355
Bergeron N et al. Interaction between dietary proteins and lipids in the regulation of serum and liver lipids in the rabbit. Effect of fish protein. 1991 Lipids pmid:1762524
Hare WR and Wahle KW The participation of soluble factors in the omega-oxidation of fatty acids in the liver of the sheep. 1991 Lipids pmid:2051891
Giera DD and van Lier RB A convenient method for the determination of hepatic lauric acid omega-oxidation based on solvent partition. 1991 Fundam Appl Toxicol pmid:2055365
Nordström T et al. Inhibition of CD3-induced Ca2+ signals in Jurkat T-cells by myristic acid. 1991 Cell Calcium pmid:1834341
Ogiso T et al. Enhancement effect of lauric acid on the rectal absorption of propranolol from suppository in rats. 1991 Chem. Pharm. Bull. pmid:1806286
Watanabe T et al. Co-suppression by nicardipine, a calcium antagonist, of induction of microsomal lauric acid hydroxylation with peroxisome proliferation in clofibrate-treated rat liver. 1991 Chem. Pharm. Bull. pmid:1914008
Hara H et al. Effect of (+/-)-2-(dimethylamino)-1-[[o-(m-methoxyphenethyl)phenoxy] methyl]ethyl hydrogen succinate on experimental models of peripheral obstructive disease. 1991 Arzneimittelforschung pmid:1930349
Ogiso T et al. Enhancement by fatty acids of the rectal absorption of propranolol: in vitro evaluation in the rat. 1991 J. Pharmacobio-dyn. pmid:1802986
Yamada J et al. Assay of fatty acid omega-hydroxylation using high-performance liquid chromatography with fluorescence labeling reagent, 3-bromomethyl-7-methoxy-1,4-benzoxazin-2-one (BrMB). 1991 Anal. Biochem. pmid:1839651
Dirven HA et al. Determination of the cytochrome P-450 IV marker, omega-hydroxylauric acid, by high-performance liquid chromatography and fluorimetric detection. 1991 J. Chromatogr. pmid:1860919
Maurich V et al. p-nitrophenyllaurate: a substrate for the high-performance liquid chromatographic determination of lipase activity. 1991 J. Chromatogr. pmid:1939456