lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

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Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Prostatic Hyperplasia D011470 20 associated lipids
Brain Infarction D020520 17 associated lipids
Stroke D020521 32 associated lipids
Starvation D013217 47 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Seizures D012640 87 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Cerebral Infarction D002544 6 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Per page 10 20 50 | Total 33

PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with lauric acid?

Related references are published most in these journals:

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What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

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Authors Title Published Journal PubMed Link
Lake BG et al. Comparative studies of the hepatic effects of di- and mono-n-octyl phthalates, di-(2-ethylhexyl) phthalate and clofibrate in the rat. 1984 Acta Pharmacol Toxicol (Copenh) pmid:6720315
Lake BG et al. The effect of hypolipidaemic agents on peroxisomal beta-oxidation and mixed-function oxidase activities in primary cultures of rat hepatocytes. Relationship between induction of palmitoyl-CoA oxidation and lauric acid hydroxylation. 1984 Xenobiotica pmid:6711016
Ortiz de Montellano PR and Reich NO Specific inactivation of hepatic fatty acid hydroxylases by acetylenic fatty acids. 1984 J. Biol. Chem. pmid:6706995
van der Valk PG et al. Skin irritancy of surfactants as assessed by water vapor loss measurements. 1984 J. Invest. Dermatol. pmid:6699429
Bugaut M et al. An examination of the stereochemical course of acylation of 2-monoacylglycerols by rat intestinal villus cells using [2H3]palmitic acid. 1984 Biochim. Biophys. Acta pmid:6696934
Gibson WT and Teall MR Interactions of C12 surfactants with the skin: studies on enzyme release and percutaneous absorption in vitro. 1983 Food Chem. Toxicol. pmid:6686185
Weisshaar R and Lingens F The lipopolysaccharide of a chloridazon-degrading bacterium. 1983 Eur. J. Biochem. pmid:6653551
Kamachi S et al. Spectrophotometric assay for lipase in serum using a chromogenic substrate, Orange I laurate. 1983 Chem. Pharm. Bull. pmid:6652817
Hasumura S et al. Effects of starvation on microsomal cytochrome P-450 and laurate-omega-hydroxylation of rat kidney and liver. 1983 Jpn. J. Pharmacol. pmid:6645119
Kimura RE et al. Decreased oxidative metabolism in neonatal rat lung exposed to hyperoxia. 1983 J Appl Physiol Respir Environ Exerc Physiol pmid:6643186
Takabayashi K et al. Coupling between fatty acid binding and sulfhydryl oxidation in bovine serum albumin. 1983 Eur. J. Biochem. pmid:6628382
Dailey MO and Hunter RL Induction of cell-mediated immunity to chemically modified antigens in guinea pigs. I. Characterization of the immune response to lipid-conjugated protein antigens. 1977 J. Immunol. pmid:66275
Fink AS et al. Pancreatic polypeptide release by intraluminal fatty acids. 1983 Metab. Clin. Exp. pmid:6621364
Kaku M et al. Purification and characterization of cytochrome P-450 specific for prostaglandin and fatty acid hydroxylase activities from the microsomes of rabbit small intestinal mucosa. 1984 J. Biochem. pmid:6530401
Takahashi K et al. Modified lipoprotein lipase catalyzes ester synthesis in benzene. Substrate specificity. 1984 Enzyme pmid:6526000
Brunner G [Progress on the way to an "artificial liver"]. 1984 Leber Magen Darm pmid:6513719
Philipson KD Interaction of charged amphiphiles with Na+-Ca2+ exchange in cardiac sarcolemmal vesicles. 1984 J. Biol. Chem. pmid:6501286
ZaÄ­tsev AN et al. [Toxicological characteristics of disodium salt of N-lauroyl-L-glutamic acid--a surface-active agent used in the food processing industry]. 1984 Jul-Aug Vopr Pitan pmid:6485298
Guesnet P et al. [Nutritional correction of an excess of unsaturated fatty acids in the body lipids of the growing rat]. 1984 Reprod Nutr Dev pmid:6484304
pmid:6479871
Segawa A et al. Suppression of IgE antibody response by the fatty acid-modified antigen. 1981 Int. Arch. Allergy Appl. Immunol. pmid:6456998
Ikeda S et al. Effect of nicomol on high density lipoprotein (HDL) subfractions, HDL2e and HDL3e, separated by electrophoresis. 1981 Acta Med. Okayama pmid:6456646
Jondorf WR and Moss MS Radioimmunoassay technique for detecting urinary excretion products after administration of synthetic anabolic steroids to the horse. 1978 Xenobiotica pmid:645104
O'Doherty PJ Regulation of ethanolamine and choline phosphatide biosynthesis in isolated rat intestinal villus cells. 1980 Can. J. Biochem. pmid:6449990
Lake BG et al. The effect of peroxisome proliferators on the metabolism and spectral interaction of endogenous substrates of cytochrome P-450 in rat hepatic microsomes. 1984 Life Sci. pmid:6439971
Tabatabai LB and Deyoe BL Biochemical and biological properties of soluble protein preparations from Brucella abortus. 1984 Dev. Biol. Stand. pmid:6436094
Chua MM et al. Attachment of immunoglobulin to liposomal membrane via protein carbohydrate. 1984 Biochim. Biophys. Acta pmid:6432057
Chopra IJ et al. A competitive ligand binding assay for measurement of thyroid hormone-binding inhibitor in serum and tissues. 1984 J. Clin. Endocrinol. Metab. pmid:6421865
Harada N and Negishi M Mouse liver testosterone 15 alpha-hydroxylase (cytochrome P-450(15) alpha). Purification, regioselectivity, stereospecificity, and sex-dependent expression. 1984 J. Biol. Chem. pmid:6420405
Siess MH et al. [The effect of cholesterol and the nature of dietary fatty acids on the activities of some microsomal monooxygenases in the rat liver]. 1983 Reprod Nutr Dev pmid:6405460
Lamikanra A and Sholola OA A study of the activity of soft soaps prepared from a homologous series of saturated fatty acids against cells of Escherichia coli NCTC 9001. 1984 Microbios pmid:6397680
Laurila H et al. The cytochrome P450-containing monooxygenase of Trichosporon cutaneum: occurrence and properties. 1984 Arch. Microbiol. pmid:6397156
Ramsey BL and Westphal U Steroid-protein interactions. 40. The effect of fatty acids on progesterone binding to human serum albumin. 1978 Biochim. Biophys. Acta pmid:638175
Berschauer F et al. [Nutritive physiological effect of dietary fats in growing swine rations. 3. Effect of sunflower and coconut kernels on protein and fat retention, backfat fatty acid pattern and various blood parameters in piglets]. 1983 Arch Tierernahr pmid:6370196
Malin-Berdel J and Valet G Flow cytometric determination of esterase and phosphatase activities and kinetics in hematopoietic cells with fluorogenic substrates. 1980 Cytometry pmid:6266787
Traul KA et al. Two-stage carcinogenesis in vitro: transformation of 3-methylcholanthrene-initiated Rauscher murine leukemia virus-infected rat embryo cells by diverse tumor promoters. 1981 J. Natl. Cancer Inst. pmid:6256572
Jacques NA Membrane perturbation by cerulenin modulates glucosyltransferase secretion and acetate uptake by Streptococcus salivarius. 1983 J. Gen. Microbiol. pmid:6229601
Albro PW et al. In vitro metabolism of mono-2-ethylhexyl phthalate by microsomal enzymes. Similarity to omega- and (omega-1) oxidation of fatty acids. 1984 Nov-Dec Drug Metab. Dispos. pmid:6150824
Orton TC and Parker GL The effect of hypolipidemic agents on the hepatic microsomal drug-metabolizing enzyme system of the rat. Induction of cytochrome(s) P-450 with specificity toward terminal hydroxylation of lauric acid. 1982 Mar-Apr Drug Metab. Dispos. pmid:6124394
Dell HD et al. Etofenamate fatty acid asters. An example of a new route of drug metabolism. 1982 Jan-Feb Drug Metab. Dispos. pmid:6124384
Demarne Y et al. Effects of maternal dodecanoic or lauric acid (C12:0) feeding on milk fatty acid secretion and lipogenesis in the suckling rat. 1977 Biol. Neonate pmid:610766
Okita RT and Masters BS Effect of phenobarbital treatment and cytochrome P-450 inhibitors on the laurate omega- and (omega - 1)-hydroxylase activities of rat liver microsomes. 1980 May-Jun Drug Metab. Dispos. pmid:6104577
Fan LL et al. Microsomal lauric acid 11- and 12-hydroxylation: a new assay method utilizing high pressure liquid chromatography. 1976 Anal. Biochem. pmid:5910
Jenkins CL et al. Fatty acid composition of Simonsiella strains. 1977 Arch. Microbiol. pmid:560178
Kato A and Arima K Inhibitory effect of sucrose ester of lauric acid on the growth of Escherichia coli. 1971 Biochem. Biophys. Res. Commun. pmid:5543940
Srivastava KC Effect of some saturated and unsaturated fatty acids on in vitro platelet utilization of arachidonic acid. 1979 Prostaglandins Med pmid:550161
Okita RT et al. Lauric acid hydroxylation in human liver and kidney cortex microsomes. 1979 Biochem. Pharmacol. pmid:533546
Kaffarnik H and Meyer-Bertenrath JG [Pancreas specificity of the oral function test using fluorescein di-or. monolaurate, respectively]. 1971 Verh Dtsch Ges Inn Med pmid:5155888
Starha L and Chalabala M [Oral long-acting drugs. 8. Effects of palmitic and lauric acid and their glycerine esters on the slowing of the drug release]. 1972 Cesk Farm pmid:5075740
Spector AA et al. Quantitative analysis of uptake of free fatty acid by mammalian cells: lauric acid and human erythrocytes. 1972 J. Lipid Res. pmid:5041270
Matĕjicek E [Academician Prof. Dr. Karol Siska, M.D., Dr.Sc., bearer of the Order of Work and laureate of the State Prize of the Slovak Socialistic Republic, 65th anniversary]. 1971 Bratisl Lek Listy pmid:4929369
Gumpen S et al. Thermal stability of fatty acid-serum albumin complexes studied by differential scanning calorimetry. 1979 Biochim. Biophys. Acta pmid:486509
Pittet PG et al. Site differences in the fatty acid composition of subcutaneous adipose tissue of obese women. 1979 Br. J. Nutr. pmid:486394
Larionova TI et al. [Effect of barium-cadmium laurate on certain enzymatic processes in the liver]. 1974 Gig Tr Prof Zabol pmid:4847171
Elkhouly AE and Woodroffe RC Effects of polyethylene glycol 400 monolaurate and sodium chloride mixtures on the antibacterial activity of solubilized trichlorocarbanilide. 1973 J. Appl. Bacteriol. pmid:4753413
Björkhem I On the mechanism of 11-hydroxylation of lauric acid by rat liver microsomes. 1973 Biochem. Biophys. Res. Commun. pmid:4689066
Kabara JJ et al. Fatty acids and derivatives as antimicrobial agents. 1972 Antimicrob. Agents Chemother. pmid:4670656
Björkhem I and Hamberg M On the rate-limiting step in W-hydroxylation of lauric acid. 1972 Biochem. Biophys. Res. Commun. pmid:4662395
Stodtmeister W et al. [Fatty acid composition of lipids from the hair in psoriasis vulgaris (author's transl)]. 1979 Arch. Dermatol. Res. pmid:464651
Ball D Robert Bridges. Doctor of Medicine and Poet Laureate. 1974 Practitioner pmid:4614250
Rindsig RB and Schultz LH Effect of feeding lauric acid to lactating cows on milk composition, rumen fermentation, and blood lipids. 1974 J. Dairy Sci. pmid:4430768
Boersma ER Changes in fatty-acid composition of body fat before and after birth in Tanzania: an international comparative study. 1979 Br Med J pmid:435841
Shlosberg A and Egyed MN Mass poisoning in cattle, palm doves and mink caused by the coccidiostat dibutyltin dilaurate. 1979 Vet Hum Toxicol pmid:425288
Sasame HA et al. The possible involvement of cytochrome b5 in the oxidation of lauric acid by microsomes from kidney cortex and liver of rats. 1974 Life Sci. pmid:4129689
Migliore-Samour D et al. Adjuvant activities of chemically modified water-soluble substances from Mycobacterium tuberculosis. 1977 Immunology pmid:411741
Chanussot F and Debry G [Comparison in genetically obese and normal rats of the uptake and incorporation of labelled lauric acid, oleic acid, and glycerol by the isolated perfused liver]. 1977 C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. pmid:411584
Chanussot F and Debry G [Comparison in genetically obese and normal rats in the secretion of lipids synthesized from labeled lauric and oleic acids and glycerol in isolated perfused liver]. 1977 C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. pmid:410533
Demarne Y et al. [Effects of prolonged ingestion of dodecanoic or lauric acid on the secretion of fatty acids in the rat mammary gland]. 1977 C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. pmid:409546
Weber N Metabolism of orally administered rac-1-O-[1'-14C]dodecylglycerol and nutritional effects of dietary rac-1-O-dodecylglycerol in mice. 1985 J. Lipid Res. pmid:4086944
Hotke C et al. Jejunal uptake of sugars, cholesterol, fatty acids, and fatty alcohols in vivo in diabetic rats. 1985 Can. J. Physiol. Pharmacol. pmid:4075254
Kawamura K et al. Effect of cilostazol, a new antithrombotic drug, on an experimental model of peripheral circulation insufficiency. 1985 Arzneimittelforschung pmid:4074428
Kitajima Y and Thompson GA Self-regulation of membrane fluidity. The effect of saturated normal and methoxy fatty acid supplementation on Tetrahymena membrane physical properties and lipid composition. 1977 Biochim. Biophys. Acta pmid:406916
Gibson GG and Bains SK Cytochrome P-450 isoenzymes involved in fatty acid metabolism. 1985 Biochem. Soc. Trans. pmid:4065418
Pita ML et al. Influence of the mother's weight and socioeconomic status on the fatty acid composition of human milk. 1985 Ann. Nutr. Metab. pmid:4062247
Norman HA and Thompson GA Effects of low-temperature stress on the metabolism of phosphatidylglycerol molecular species in Dunaliella salina. 1985 Arch. Biochem. Biophys. pmid:4051499
Halpert J et al. Isozyme selectivity of the inhibition of rat liver cytochromes P-450 by chloramphenicol in vivo. 1985 Mol. Pharmacol. pmid:4033629
Rafflenbeul D and Zbinden G Circulating platelet aggregates and thrombocytopenia induced by intravenous infusions of arachidonic and lauric acids in guinea pigs. 1977 Acta Haematol. pmid:402770
Shoun H et al. Subterminal hydroxylation of fatty acids by a cytochrome P-450-dependent enzyme system from a fungus, Fusarium oxysporum. 1985 J. Biochem. pmid:4019433
Kaku M et al. Multiple forms of cytochrome P-450 in rabbit colon microsomes. 1985 J. Biochem. pmid:4008473
Spencer GK and Waldroup PW The influence of amprolium and butynorate on growth rate and feed utilization by large white turkeys. 1985 Poult. Sci. pmid:4001047
Qureshi N et al. Monophosphoryl lipid A obtained from lipopolysaccharides of Salmonella minnesota R595. Purification of the dimethyl derivative by high performance liquid chromatography and complete structural determination. 1985 J. Biol. Chem. pmid:3988753
Thomson AB Resection of rabbit ileum: effect on jejunal structure and carrier-mediated and passive uptake. 1986 Q J Exp Physiol pmid:3952260
Pedersen AO et al. Laurate binding to human serum albumin. Multiple binding equilibria investigated by a dialysis exchange method. 1986 Eur. J. Biochem. pmid:3948866
Cresteil T et al. Cytochrome P-450 isoenzyme content and monooxygenase activities in rat liver: effect of ontogenesis and pretreatment by phenobarbital and 3-methylcholanthrene. 1986 J. Pharmacol. Exp. Ther. pmid:3941398
Capdevila J et al. Influence of a fibric acid type of hypolipidemic agent on the oxidative metabolism of arachidonic acid by liver microsomal cytochrome P-450. 1985 Arch. Biochem. Biophys. pmid:3933431
Fournel S et al. Structure-dependent induction of bilirubin glucuronidation and lauric acid 12-hydroxylation by arylcarboxylic acids chemically related to clofibrate. 1985 Biochim. Biophys. Acta pmid:3931693
Bains SK et al. Immunochemical study on the contribution of hypolipidaemic-induced cytochrome P-452 to the metabolism of lauric acid and arachidonic acid. 1985 Biochem. Pharmacol. pmid:3929789
Takahashi K et al. Ester synthesis at extraordinarily low temperature of -3 degrees C by modified lipase in benzene. 1985 Biochem. Int. pmid:3927919
Kameda K and Imai Y Isolation and characterization of the multiple charge isoforms of acyl-CoA synthetase from Escherichia coli. 1985 Biochim. Biophys. Acta pmid:3907712
Otomo S et al. Prostaglandin E1 incorporated in lipid microspheres (lipo PGE1). 1985 Drugs Exp Clin Res pmid:3880049
Hawke RL and Welch RM Major differences in the specificity and regulation of mouse renal cytochrome P-450-dependent monooxygenases. A comparison of xenobiotic and endogenous substrates. 1985 Mol. Pharmacol. pmid:3875782
Aponte GW et al. Regional distribution and release of peptide YY with fatty acids of different chain length. 1985 Am. J. Physiol. pmid:3841263
Kameshita I et al. Phosphoenolpyruvate carboxylase of Escherichia coli. Effect of proteolytic modification on the catalytic and regulatory propties. 1979 J. Biochem. pmid:383705
Goto J et al. A comparison of the effect of Lipo PGE1 and other related compounds on experimental peripheral arterial occlusive disease in rats. 1986 Drugs Exp Clin Res pmid:3816509
Yoshimoto M et al. Purification and characterization of two forms of cytochrome P-450 from rat kidney cortex microsomes. 1986 Biochem. Int. pmid:3814156
Brodersen R et al. Cobinding of bilirubin and sulfonamide and of two bilirubin molecules to human serum albumin: a site model. 1987 Arch. Biochem. Biophys. pmid:3813550
Kolattukudy PE and Rogers L Biosynthesis of 3-hydroxy fatty acids, the pheromone components of female mallard ducks, by cell-free preparations from the uropygial gland. 1987 Arch. Biochem. Biophys. pmid:3813530
Imaoka S and Funae Y Purification and NH2-terminal sequence of cytochrome P-450 from kidney microsomes of untreated male rats. 1986 Biochem. Biophys. Res. Commun. pmid:3801020
Okita R Effect of acetylsalicylic acid on fatty acid omega-hydroxylation in rat liver. 1986 Pediatr. Res. pmid:3797113
Renner HW The anticlastogenic potential of fatty acid methyl esters. 1986 Mutat. Res. pmid:3785274