lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

Cross Reference

Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Liver Neoplasms, Experimental D008114 46 associated lipids
Starvation D013217 47 associated lipids
Thrombosis D013927 49 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Hyperlipidemias D006949 73 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Atherosclerosis D050197 85 associated lipids
Seizures D012640 87 associated lipids
Hemolysis D006461 131 associated lipids
Per page 10 20 50 | Total 33

PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

Download all related citations
Per page 10 20 50 100 | Total 1837
Authors Title Published Journal PubMed Link
Ost TW et al. Phenylalanine 393 exerts thermodynamic control over the heme of flavocytochrome P450 BM3. 2001 Biochemistry pmid:11695888
Ellis CD et al. The Neisseria gonorrhoeae lpxLII gene encodes for a late-functioning lauroyl acyl transferase, and a null mutation within the gene has a significant effect on the induction of acute inflammatory responses. 2001 Mol. Microbiol. pmid:11679076
Hlongwane C et al. Comparative quantitative fatty acid analysis of triacylglycerols using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and gas chromatography. 2001 Rapid Commun. Mass Spectrom. pmid:11675670
General S and Thünemann AF pH-sensitive nanoparticles of poly(amino acid) dodecanoate complexes. 2001 Int J Pharm pmid:11672952
Uchida T et al. Preparation and characterization of insulin-loaded acrylic hydrogels containing absorption enhancers. 2001 Chem. Pharm. Bull. pmid:11605651
Park SJ et al. Production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) by metabolically engineered Escherichia coli strains. 2001 Biomacromolecules pmid:11749180
Yata T et al. Amino acids protect epithelial cells from local toxicity by absorption enhancer, sodium laurate. 2001 J Pharm Sci pmid:11745705
Aoki T et al. Cholesterol-lowering effect of NK-104, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, in guinea pig model of hyperlipidemia. 2001 Arzneimittelforschung pmid:11304935
Gross V et al. Inhibition of pressure natriuresis in mice lacking the AT2 receptor. 2000 Kidney Int. pmid:10620200
Hoch U et al. Structural determination of the substrate specificities and regioselectivities of the rat and human fatty acid omega-hydroxylases. 2000 Arch. Biochem. Biophys. pmid:10620324
Aussel L et al. Novel variation of lipid A structures in strains of different Yersinia species. 2000 FEBS Lett. pmid:10620712
Nakagawa T et al. Peroxisomal membrane protein Pmp47 is essential in the metabolism of middle-chain fatty acid in yeast peroxisomes and Is associated with peroxisome proliferation. 2000 J. Biol. Chem. pmid:10652339
Lee SH et al. Production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) by high-cell-density cultivation of Aeromonas hydrophila. 2000 Biotechnol. Bioeng. pmid:10592522
Casolo V et al. The role of mild uncoupling and non-coupled respiration in the regulation of hydrogen peroxide generation by plant mitochondria. 2000 FEBS Lett. pmid:10828450
Sinninghe Damsté JS et al. Structural identification of the diester preen-gland waxes of the red knot (Calidris canutus). 2000 J. Nat. Prod. pmid:10757724
Song B et al. Description of strain 3CB-1, a genomovar of Thauera aromatica, capable of degrading 3-chlorobenzoate coupled to nitrate reduction. 2000 Int. J. Syst. Evol. Microbiol. pmid:10758860
van der Bijl P et al. Permeation of sumatriptan through human vaginal and buccal mucosa. 2000 Headache pmid:10759913
Stewart JM and Blakely JA Long chain fatty acids inhibit and medium chain fatty acids activate mammalian cardiac hexokinase. 2000 Biochim. Biophys. Acta pmid:10760476
Sheffield C The new laureate speaks. 2000 Nature pmid:10766219
Ayorinde FO et al. Determination of the fatty acid composition of saponified vegetable oils using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. 2000 Rapid Commun. Mass Spectrom. pmid:10775096
Sulikowski GA et al. Investigations into a biomimetic approach toward CP-225,917 and CP-263,114. 2000 J. Org. Chem. pmid:10813939
Hsu AF et al. Immobilization of Pseudomonas cepacia lipase in a phyllosilicate sol-gel matrix: effectiveness as a biocatalyst. 2000 Biotechnol. Appl. Biochem. pmid:10814587
Dong GC et al. Preparation and characterization of surface-modified calcium hydrogenphosphate by hexamethylene diisocyanates. 2000 Biomed Sci Instrum pmid:10834217
Hong JT and Glauert HP Effect of extracellular matrix on the expression of peroxisome proliferation associated genes in cultured rat hepatocytes. 2000 Toxicol In Vitro pmid:10793296
Govender T et al. Defining the drug incorporation properties of PLA-PEG nanoparticles. 2000 Int J Pharm pmid:10794931
Pereira JR et al. Inversion in the change of the refractive index and memory effect near the nematic-isotropic phase transition in a lyotropic liquid crystal. 2000 Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics pmid:11031592
Buhler DR et al. Effects of 17beta-estradiol and testosterone on hepatic mRNA/protein levels and catalytic activities of CYP2M1, CYP2K1, and CYP3A27 in rainbow trout (Oncorhynchus mykiss). 2000 Toxicol. Appl. Pharmacol. pmid:11032764
Pantaler E et al. Acceleration of phospholipid flip-flop in the erythrocyte membrane by detergents differing in polar head group and alkyl chain length. 2000 Biochim. Biophys. Acta pmid:11118549
Soetanto K and Chan M Study on the lifetime and attenuation properties of microbubbles coated with carboxylic acid salts. 2000 Ultrasonics pmid:11106009
Loughran PA et al. Identification of unique amino acids that modulate CYP4A7 activity. 2000 Biochemistry pmid:11106489
Yang YH et al. Heterologous expression of CYP2K1 and identification of the expressed protein (BV-CYP2K1) as lauric acid (omega-1)-hydroxylase and aflatoxin B1 exo-epoxidase. 2000 Drug Metab. Dispos. pmid:11038153
Hashemi E et al. Stability of cytochrome P450 proteins in cultured precision-cut rat liver slices. 2000 Toxicology pmid:10967402
Giorgi M et al. Cytochrome P450-dependent monooxygenase activities and their inducibility by classic P450 inducers in the liver, kidney, and nasal mucosa of male adult ring-necked pheasants. 2000 Toxicol. Appl. Pharmacol. pmid:10986015
Imaishi H et al. CYP78A1 preferentially expressed in developing inflorescences of Zea mays encoded a cytochrome P450-dependent lauric acid 12-monooxygenase. 2000 Biosci. Biotechnol. Biochem. pmid:10993158
Nielsen AD et al. Thermochemistry of the specific binding of C12 surfactants to bovine serum albumin. 2000 Biochim. Biophys. Acta pmid:11004550
DeLany JP et al. Differential oxidation of individual dietary fatty acids in humans. 2000 Am. J. Clin. Nutr. pmid:11010930
Saffert A et al. A dual function alpha-dioxygenase-peroxidase and NAD(+) oxidoreductase active enzyme from germinating pea rationalizing alpha-oxidation of fatty acids in plants. 2000 Plant Physiol. pmid:10938370
Toshima Y et al. A new model of cerebral microthrombosis in rats and the neuroprotective effect of a Rho-kinase inhibitor. 2000 Stroke pmid:10978059
Santoyo S and Ygartua P Effect of skin pretreatment with fatty acids on percutaneous absorption and skin retention of piroxicam after its topical application. 2000 Eur J Pharm Biopharm pmid:10962234
Ohk SH and Kuramitsu HK A novel antibacterial agent derived from the C-terminal domain of streptococcus mutans GTP-binding protein. 2000 J. Antimicrob. Chemother. pmid:10882696
Kawashima H et al. Human fatty acid omega-hydroxylase, CYP4A11: determination of complete genomic sequence and characterization of purified recombinant protein. 2000 Arch. Biochem. Biophys. pmid:10860550
Hoch U et al. Molecular basis for the omega-regiospecificity of the CYP4A2 and CYP4A3 fatty acid hydroxylases. 2000 J. Biol. Chem. pmid:10869363
Imai Y et al. Unique heme environment at the putative distal region of hydrogen peroxide-dependent fatty acid alpha-hydroxylase from Sphingomonas paucimobilis (peroxygenase P450(SPalpha). 2000 J. Biochem. pmid:10920253
Samartsev VN et al. Comparative study on uncoupling effects of laurate and lauryl sulfate on rat liver and skeletal muscle mitochondria. 2000 Biochim. Biophys. Acta pmid:10924910
Arrol S et al. The effects of fatty acids on apolipoprotein B secretion by human hepatoma cells (HEP G2). 2000 Atherosclerosis pmid:10856517
Tang L et al. A kinetic study of the synthesis of ascorbate fatty acid esters catalysed by immobilized lipase in organic media. 2000 Biotechnol. Appl. Biochem. pmid:10918036
Ogiso T et al. Percutaneous penetration of ozagrel and the enhancement produced by saturated fatty acids. 2000 Biol. Pharm. Bull. pmid:10919364
Buszello K et al. The influence of alkali fatty acids on the properties and the stability of parenteral O/W emulsions modified with solutol HS 15. 2000 Eur J Pharm Biopharm pmid:10704897
Lake BG et al. Species differences in hepatic peroxisome proliferation, cell replication and transforming growth factor-beta1 gene expression in the rat, Syrian hamster and guinea pig. 2000 Mutat. Res. pmid:10725474
Saito A et al. Effects of capsaicin on biliary free fatty acids in rats. 2000 Int J Vitam Nutr Res pmid:10683757
Tsuge T et al. Molecular cloning of two (R)-specific enoyl-CoA hydratase genes from Pseudomonas aeruginosa and their use for polyhydroxyalkanoate synthesis. 2000 FEMS Microbiol. Lett. pmid:10713420
Soetanto K and Chan M Fundamental studies on contrast images from different-sized microbubbles: analytical and experimental studies. 2000 Ultrasound Med Biol pmid:10687796
Kamm W et al. Evaluation of absorption enhancement for a potent cyclopeptidic alpha(nu)beta(3)-antagonist in a human intestinal cell line (Caco-2). 2000 Eur J Pharm Sci pmid:10767598
Betts KS Laureate extols genetic engineering's value for aiding hungry developing nations. 2000 Environ. Sci. Technol. pmid:21657573
Sidhu SS et al. Fatty acid-induced cholecystokinin secretion and changes in intracellular Ca2+ in two enteroendocrine cell lines, STC-1 and GLUTag. 2000 J. Physiol. (Lond.) pmid:11018115
Wiberg E et al. The distribution of caprylate, caprate and laurate in lipids from developing and mature seeds of transgenic Brassica napus L. 2000 Planta pmid:11219581
Abigor RD et al. Lipase-catalysed production of biodiesel fuel from some Nigerian lauric oils. 2000 Biochem. Soc. Trans. pmid:11171279
Ngo S et al. Cytochrome P450 4A, peroxisomal enzymes and nicotinamide cofactors in koala liver. 2000 Comp. Biochem. Physiol. C Toxicol. Pharmacol. pmid:11246504
Kwok CS et al. Surface modification of polymers with self-assembled molecular structures: multitechnique surface characterization. 2000 Biomacromolecules pmid:11709836
Reginster JY et al. Estradiol pharmacokinetics after transdermal application of patches to postmenopausal women: matrix versus reservoir patches. 2000 Climacteric pmid:11910618
Cunha MT et al. Effect of salts and surfactants on the partitioning of Fusarium solani pisi cutinase in aqueous two-phase systems of thermoseparating ethylene oxide/propylene oxide random copolymer and hydroxypropyl starch. 2000 Bioseparation pmid:11321518
Amet Y et al. Adaptation to chronic ethanol administration emphasized by fatty acid hydroxylations in rat liver and kidney microsomes. 2000 Eur J Nutr pmid:11395987
Kikuta Y et al. Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14. 2000 Arch. Biochem. Biophys. pmid:11185557
Goodfriend TL et al. Plasma aldosterone, plasma lipoproteins, obesity and insulin resistance in humans. 1999 May-Jun Prostaglandins Leukot. Essent. Fatty Acids pmid:10471129
Bardi L et al. Saccharomyces cerevisiae cell fatty acid composition and release during fermentation without aeration and in absence of exogenous lipids. 1999 Int. J. Food Microbiol. pmid:10357281
NTP Toxicology and Carcinogenesis Studies of Lauric Acid Diethanolamine Condensate (CAS NO. 120-40-1) in F344/N Rats and B6C3F1 Mice (Dermal Studies). 1999 Natl Toxicol Program Tech Rep Ser pmid:12571683
Tsai YH et al. Mechanisms mediating lipoprotein responses to diets with medium-chain triglyceride and lauric acid. 1999 Lipids pmid:10574653
Cazeils JL et al. Lipid composition of hepatocyte plasma membranes from geese overfed with corn. 1999 Lipids pmid:10574658
Imaishi H et al. Encoding of a cytochrome P450-dependent lauric acid monooxygenase by CYP703A1 specifically expressed in the floral buds of petunia hybrida. 1999 Biosci. Biotechnol. Biochem. pmid:10664841
Glasgow BJ et al. Tear lipocalins: potential lipid scavengers for the corneal surface. 1999 Invest. Ophthalmol. Vis. Sci. pmid:10586930
Sabourault C et al. Tissue-specific induction and inactivation of cytochrome P450 catalysing lauric acid hydroxylation in the sea bass, Dicentrarchus labrax. 1999 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:10327614
Yamazaki H and Shimada T Effects of arachidonic acid, prostaglandins, retinol, retinoic acid and cholecalciferol on xenobiotic oxidations catalysed by human cytochrome P450 enzymes. 1999 Xenobiotica pmid:10219964
Murakami K et al. Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha. 1999 Biochem. Biophys. Res. Commun. pmid:10403814
Temme EH et al. Effects of diets enriched in lauric, palmitic or oleic acids on blood coagulation and fibrinolysis. 1999 Thromb. Haemost. pmid:10064003
Robinson MK et al. A two-center study of the development of acute irritation responses to fatty acids. 1999 Am. J. Contact Dermatitis pmid:10444106
Crawford TO et al. Abnormal fatty acid metabolism in childhood spinal muscular atrophy. 1999 Ann. Neurol. pmid:10072048
Haining RL et al. Enzymatic determinants of the substrate specificity of CYP2C9: role of B'-C loop residues in providing the pi-stacking anchor site for warfarin binding. 1999 Biochemistry pmid:10079071
Chang YT and Loew GH Homology modeling and substrate binding study of human CYP4A11 enzyme. 1999 Proteins pmid:10024026
Lagrost L et al. Variations in serum cholesteryl ester transfer and phospholipid transfer activities in healthy women and men consuming diets enriched in lauric, palmitic or oleic acids. 1999 Atherosclerosis pmid:10030391
Richieri GV et al. Binding kinetics of engineered mutants provide insight about the pathway for entering and exiting the intestinal fatty acid binding protein. 1999 Biochemistry pmid:10231541
Bardi L et al. Esterase activity and release of ethyl esters of medium-chain fatty acids by Saccharomyces cerevisiae during anaerobic growth. 1998 Can. J. Microbiol. pmid:10347863
Lindmark T et al. Absorption enhancement through intracellular regulation of tight junction permeability by medium chain fatty acids in Caco-2 cells. 1998 J. Pharmacol. Exp. Ther. pmid:9435199
Grinberg F et al. A new formalism for the evaluation of order-fluctuation modes in liquid crystals from field-cycling NMR-relaxometry data. 1998 J. Magn. Reson. pmid:9799675
Temme EH et al. Individual saturated fatty acids and effects on whole blood aggregation in vitro. 1998 Eur J Clin Nutr pmid:9805214
Crespi CL et al. Determination of CYP4A11-catalyzed lauric acid 12-hydroxylation by high-performance liquid chromatography with radiometric detection. 1998 Methods Mol. Biol. pmid:14577226
Meyer JH et al. Length of intestinal contact on nutrient-driven satiety. 1998 Am. J. Physiol. pmid:9756564
Guan X et al. Cytochrome P450-dependent desaturation of lauric acid: isoform selectivity and mechanism of formation of 11-dodecenoic acid. 1998 Chem. Biol. Interact. pmid:9566728
Miura Y and Oda S Oxidation of fatty acids by kidney microsomes of musk shrew (Suncus murinus). 1998 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:9530812
Amet Y et al. P-450-dependent metabolism of lauric acid in alcoholic liver disease: comparison between rat liver and kidney microsomes. 1998 Alcohol. Clin. Exp. Res. pmid:9581653
Oszi Z and Pethö G Quantitative determination of polysorbate 20 in nasal pharmaceutical preparations by high-performance liquid chromatography. 1998 J Pharm Biomed Anal pmid:9919973
Andersen Borge GI et al. Fatty acid alpha-oxidation of tetradecylthioacetic acid and tetradecylthiopropionic acid in cucumber (Cucumis sativus). 1998 Biochim. Biophys. Acta pmid:9795197
Orellana M et al. Peroxisomal and microsomal fatty acid oxidation in liver of rats after chronic ethanol consumption. 1998 Gen. Pharmacol. pmid:9809485
Kroetz DL et al. Peroxisome proliferator-activated receptor alpha controls the hepatic CYP4A induction adaptive response to starvation and diabetes. 1998 J. Biol. Chem. pmid:9813074
Zheng YM et al. Identification of a meander region proline residue critical for heme binding to cytochrome P450: implications for the catalytic function of human CYP4B1. 1998 Biochemistry pmid:9737862
Tappenden KA et al. Short-chain fatty acid-supplemented total parenteral nutrition alters intestinal structure, glucose transporter 2 (GLUT2) mRNA and protein, and proglucagon mRNA abundance in normal rats. 1998 Am. J. Clin. Nutr. pmid:9665105
Ueda I and Suzuki A Is there a specific receptor for anesthetics? Contrary effects of alcohols and fatty acids on phase transition and bioluminescence of firefly luciferase. 1998 Biophys. J. pmid:9675206
Lee Y et al. Preparation of slightly hydrophobic heparin derivatives which can be used for solvent casting in polymeric formulation. 1998 Thromb. Res. pmid:9840023
Noble MA et al. Imidazolyl carboxylic acids as mechanistic probes of flavocytochrome P-450 BM3. 1998 Biochemistry pmid:9843385
Orellana M et al. Modulation of peroxisomal and microsomal fatty acid oxidation by acetone. A comparative study between liver and kidney. 1998 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:9972312
Amichot M et al. Induction of cytochrome P450 activities in Drosophila melanogaster strains susceptible or resistant to insecticides. 1998 Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. pmid:9972473