| MeSH term | MeSH ID | Detail |
|---|---|---|
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Starvation | D013217 | 47 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Leukemia, Myeloid | D007951 | 52 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
lauric acid
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
Cross Reference
Introduction
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with lauric acid?
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with lauric acid
PubChem Associated disorders and diseases
What pathways are associated with lauric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with lauric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with lauric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with lauric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with lauric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with lauric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with lauric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hidalgo Baltasar E et al. | Role of water structure on the high pressure micellization and phase transformations of sodium dodecanoate aqueous solutions. | 2014 | Langmuir | pmid:24903603 |
| Brunner G | [Progress on the way to an "artificial liver"]. | 1984 | Leber Magen Darm | pmid:6513719 |
| Soliva CR et al. | Effects of mixtures of lauric and myristic acid on rumen methanogens and methanogenesis in vitro. | 2003 | Lett. Appl. Microbiol. | pmid:12803553 |
| Skrivanová E et al. | Susceptibility of Clostridium perfringens to C-C fatty acids. | 2005 | Lett. Appl. Microbiol. | pmid:15960756 |
| Chen Y et al. | Antilisterial activity of lactose monolaurate in milk, drinkable yogurt and cottage cheese. | 2014 | Lett. Appl. Microbiol. | pmid:24117896 |
| Liangqi Z et al. | Synthesis of poly (3-hydroxybutyrate-co-3-hydroxyoctanoate) by a Sinorhizobium fredii strain. | 2006 | Lett. Appl. Microbiol. | pmid:16599986 |
| Fibach E and Gatt S | Clonal analysis of the response of human promyelocytic leukemia (HL-60) cells to photosensitization induced by a pyrene-containing fatty acid. | 1987 | Leuk. Res. | pmid:3480396 |
| Fibach E et al. | Analysis of cellular heterogeneity in the response of human leukemic cells to photosensitization induced by pyrene-containing fatty acid. | 1989 | Leuk. Res. | pmid:2559259 |
| Bagasra O et al. | The Libyan HIV Outbreak How do we find the truth? | 2007 | Libyan J Med | pmid:21503253 |
| Lake BG et al. | Induction of lauric acid hydroxylation and maintenance of cytochrome P-450 content by clofibrate in primary cultures of rat hepatocytes. | 1983 | Life Sci. | pmid:6865658 |
| Lake BG et al. | The effect of peroxisome proliferators on the metabolism and spectral interaction of endogenous substrates of cytochrome P-450 in rat hepatic microsomes. | 1984 | Life Sci. | pmid:6439971 |
| Sasame HA et al. | The possible involvement of cytochrome b5 in the oxidation of lauric acid by microsomes from kidney cortex and liver of rats. | 1974 | Life Sci. | pmid:4129689 |
| Piver B et al. | Differential inhibition of human cytochrome P450 enzymes by epsilon-viniferin, the dimer of resveratrol: comparison with resveratrol and polyphenols from alcoholized beverages. | 2003 | Life Sci. | pmid:12818727 |
| Mukwevho E and Joseph JS | Calmodulin dependent protein kinase II activation by exercise regulates saturated & unsaturated fatty acids and improves some metabolic syndrome markers. | 2014 | Life Sci. | pmid:25046734 |
| Pronczuk A et al. | Plasma lipids are affected similarly by dietary lauric or palmitic acid in gerbils and monkeys. | 1995 | Lipids | pmid:8614307 |
| Valdes E et al. | Dietary fish oil and cytochrome P-450 monooxygenase activity in rat liver and kidney. | 1995 | Lipids | pmid:8538384 |
| Tsai YH et al. | Mechanisms mediating lipoprotein responses to diets with medium-chain triglyceride and lauric acid. | 1999 | Lipids | pmid:10574653 |
| Cazeils JL et al. | Lipid composition of hepatocyte plasma membranes from geese overfed with corn. | 1999 | Lipids | pmid:10574658 |
| Miura Y et al. | Hydroxylation of fatty acids and alcohols by hepatic microsomal cytochrome P-450 system from the Mongolian gerbil. | 1987 | Lipids | pmid:3451012 |
| German JB and Dillard CJ | Saturated fats: a perspective from lactation and milk composition. | 2010 | Lipids | pmid:20652757 |
| Legrand P and Rioux V | The complex and important cellular and metabolic functions of saturated fatty acids. | 2010 | Lipids | pmid:20625935 |
| Bergeron N et al. | Interaction between dietary proteins and lipids in the regulation of serum and liver lipids in the rabbit. Effect of fish protein. | 1991 | Lipids | pmid:1762524 |
| Miura Y | Omega- and (omega-1)-hydroxylation of 1-dodecanol by frog liver microsomes. | 1981 | Lipids | pmid:6975411 |
| Miura Y | Effect of inhibitors on omega- and (omega-1)-hydroxylation of lauric acid by frog liver microsomes. | 1982 | Lipids | pmid:6984479 |
| Lemaire P et al. | Subterminal hydroxylation of lauric acid by microsomes from a marine fish. | 1992 | Lipids | pmid:1522763 |
| Beermann C et al. | Comparison of the structures of triacylglycerols from native and transgenic medium-chain fatty acid-enriched rape seed oil by liquid chromatography--atmospheric pressure chemical ionization ion-trap mass spectrometry (LC-APCI-ITMS). | 2007 | Lipids | pmid:17406932 |
| Legrand P et al. | Short chain saturated fatty acids decrease circulating cholesterol and increase tissue PUFA content in the rat. | 2010 | Lipids | pmid:20924709 |
| Akesson B et al. | Absorption of synthetic, stereochemically defined acylglycerols in the rat. | 1978 | Lipids | pmid:672470 |
| Hare WR and Wahle KW | The participation of soluble factors in the omega-oxidation of fatty acids in the liver of the sheep. | 1991 | Lipids | pmid:2051891 |
| Tsuzuki W | Absorption properties of micellar lipid metabolites into Caco2 cells. | 2007 | Lipids | pmid:17582542 |
| Kothari HV | Purification and properties of aortic cholesteryl ester hydrolase. | 1975 | Lipids | pmid:1134220 |
| Bugaut M | In vivo incorporation of lauric acid into rat adipose tissue triacylglycerols. | 1989 | Lipids | pmid:2761351 |
| Albro PW et al. | Rapid isolation of microsomes for studies of lipid peroxidation. | 1987 | Lipids | pmid:3123838 |
| Micha R and Mozaffarian D | Saturated fat and cardiometabolic risk factors, coronary heart disease, stroke, and diabetes: a fresh look at the evidence. | 2010 | Lipids | pmid:20354806 |
| Legrand P et al. | Lauric acid is desaturated to 12:1n-3 by hepatocytes and rat liver homogenates. | 2002 | Lipids | pmid:12120955 |
| Carballeira NM et al. | Synthesis of a novel series of 2-methylsulfanyl fatty acids and their toxicity on the human K-562 and U-937 leukemia cell lines. | 2005 | Lipids | pmid:16382579 |
| Nangue TJ et al. | Irvingia gabonensis fat: nutritional properties and effect of increasing amounts on the growth and lipid metabolism of young rats wistar sp. | 2011 | Lipids Health Dis | pmid:21375740 |
| Zhong N et al. | Solvent-free enzymatic synthesis of 1, 3-diacylglycerols by direct esterification of glycerol with saturated fatty acids. | 2013 | Lipids Health Dis | pmid:23656739 |
| Haug A et al. | Bovine milk in human nutrition--a review. | 2007 | Lipids Health Dis | pmid:17894873 |
| Blomqvist M et al. | Uptake of the glycosphingolipid sulfatide in the gastrointestinal tract and pancreas in vivo and in isolated islets of Langerhans. | 2006 | Lipids Health Dis | pmid:17044925 |
| Hwang J et al. | Dietary saturated and monounsaturated fats protect against acute acetaminophen hepatotoxicity by altering fatty acid composition of liver microsomal membrane in rats. | 2011 | Lipids Health Dis | pmid:22011590 |
| Aissa I et al. | Synthesis of lipophilic tyrosyl esters derivatives and assessment of their antimicrobial and antileishmania activities. | 2012 | Lipids Health Dis | pmid:22264330 |
| Kizhakkedathu JN et al. | Water-soluble nanoparticles from random copolymer and oppositely charged surfactant, 3a. Nanoparticles of poly(ethylene glycol)-based cationic random copolymer and fatty acid salts. | 2005 | Macromol Biosci | pmid:15948231 |
| Qiu YZ et al. | Metabolic engineering for the production of copolyesters consisting of 3-hydroxybutyrate and 3-hydroxyhexanoate by Aeromonas hydrophila. | 2004 | Macromol Biosci | pmid:15468215 |
| Tsuge T et al. | Mutation effects of a conserved alanine (Ala510) in type I polyhydroxyalkanoate synthase from Ralstonia eutropha on polyester biosynthesis. | 2004 | Macromol Biosci | pmid:15508175 |
| Iannitti T and Palmieri B | An update on the therapeutic role of alkylglycerols. | 2010 | Mar Drugs | pmid:20948908 |
| Thibane VS et al. | Effect of marine polyunsaturated fatty acids on biofilm formation of Candida albicans and Candida dubliniensis. | 2010 | Mar Drugs | pmid:21116408 |
| Leone S et al. | Molecular structure of endotoxins from Gram-negative marine bacteria: an update. | 2007 | Mar Drugs | pmid:18463721 |
| Giltrap AM et al. | Total synthesis of fellutamide B and deoxy-fellutamides B, C, and D. | 2013 | Mar Drugs | pmid:23880930 |
| Smith VJ et al. | Conventional and unconventional antimicrobials from fish, marine invertebrates and micro-algae. | 2010 | Mar Drugs | pmid:20479976 |
| Okamura Y et al. | Isolation and characterization of a GDSL esterase from the metagenome of a marine sponge-associated bacteria. | 2010 | Mar. Biotechnol. | pmid:19789923 |
| Cravedi JP and Perdu-Durand E | The phthalate diesters DEHP and DBP do not induce lauric acid hydroxylase activity in rainbow trout. | Mar. Environ. Res. | pmid:12408651 | |
| Morisaki H | [Inhibition of neutrophil function by solvent of injectable sedatives--effects of propylene glycol, ethanol and benzyl alcohol]. | 1989 | Masui | pmid:2614886 |
| Jamuna-Thevi K et al. | Triple-layered PLGA/nanoapatite/lauric acid graded composite membrane for periodontal guided bone regeneration. | 2014 | Mater Sci Eng C Mater Biol Appl | pmid:25175212 |
| Stefanescu A et al. | From the editor's desk: medline and beyond. | 2008 | Mcgill J Med | pmid:19148307 |
| Stefanescu A et al. | From the editor's desk: ethics and current medical controversies. | 2008 | Mcgill J Med | pmid:18523528 |
| Leakey JE et al. | Effects of aging and caloric restriction on hepatic drug metabolizing enzymes in the Fischer 344 rat. I: The cytochrome P-450 dependent monooxygenase system. | 1989 | Mech. Ageing Dev. | pmid:2661932 |
| Kidane AG et al. | Synthesis and evaluation of amphiphilic RGD derivatives: uses for solvent casting in polymers and tissue engineering applications. | 2003 | Med Biol Eng Comput | pmid:14686601 |
| Opthof T | Differences in citation frequency of clinical and basic science papers in cardiovascular research. | 2011 | Med Biol Eng Comput | pmid:21567267 |
| Berry D | Pierre-François Olive Rayer: biography. | 2005 | Med Hist Suppl | pmid:15981855 |
| Takahashi M et al. | [Inhibition of Candida mycelia growth by a medium chain fatty acids, capric acid in vitro and its therapeutic efficacy in murine oral candidiasis]. | 2012 | Med Mycol J | pmid:23257726 |
| Charlton BG | Why there should be more science Nobel prizes and laureates - And why proportionate credit should be awarded to institutions. | 2007 | Med. Hypotheses | pmid:17127013 |
| Ivison SM et al. | The p110α and p110β isoforms of class I phosphatidylinositol 3-kinase are involved in toll-like receptor 5 signaling in epithelial cells. | 2010 | Mediators Inflamm. | pmid:20953381 |
| Soydan AS et al. | The evaluation of the role of beta-hydroxy fatty acids on chronic inflammation and insulin resistance. | 2006 | Mediators Inflamm. | pmid:17392575 |
| Mustad VA et al. | Comparison of the effects of diets rich in stearic acid versus myristic acid and lauric acid on platelet fatty acids and excretion of thromboxane A2 and PGI2 metabolites in healthy young men. | 1993 | Metab. Clin. Exp. | pmid:8487669 |
| Fink AS et al. | Pancreatic polypeptide release by intraluminal fatty acids. | 1983 | Metab. Clin. Exp. | pmid:6621364 |
| Hong J et al. | The short-term effect of fatty acids on glucagon secretion is influenced by their chain length, spatial configuration, and degree of unsaturation: studies in vitro. | 2005 | Metab. Clin. Exp. | pmid:16154432 |
| Liu Q et al. | Biosynthesis of poly(3-hydroxydecanoate) and 3-hydroxydodecanoate dominating polyhydroxyalkanoates by β-oxidation pathway inhibited Pseudomonas putida. | 2011 | Metab. Eng. | pmid:20971206 |
| Huang WC et al. | Control of the stereo-selectivity of styrene epoxidation by cytochrome P450 BM3 using structure-based mutagenesis. | 2011 | Metallomics | pmid:21240430 |
| Jain AK and Panchagnula R | Transdermal drug delivery of tricyclic antidepressants: effect of fatty acids. | Methods Find Exp Clin Pharmacol | pmid:12949625 | |
| Crespi CL et al. | Determination of CYP4A11-catalyzed lauric acid 12-hydroxylation by high-performance liquid chromatography with radiometric detection. | 2006 | Methods Mol. Biol. | pmid:16719385 |
| Crespi CL et al. | Determination of CYP4A11-catalyzed lauric acid 12-hydroxylation by high-performance liquid chromatography with radiometric detection. | 1998 | Methods Mol. Biol. | pmid:14577226 |
| Skwarczynski M and Toth I | Lipid-core-peptide system for self-adjuvanting synthetic vaccine delivery. | 2011 | Methods Mol. Biol. | pmid:21674338 |
| De Cuyper M and Soenen SJ | Cationic magnetoliposomes. | 2010 | Methods Mol. Biol. | pmid:20072875 |
| Scheps D et al. | Synthesis of ω-hydroxy dodecanoic acid based on an engineered CYP153A fusion construct. | 2013 | Microb Biotechnol | pmid:23941649 |
| JunGang L et al. | Cloning and biochemical characterization of a novel lipolytic gene from activated sludge metagenome, and its gene product. | 2010 | Microb. Cell Fact. | pmid:21054894 |
| Zhang T and Han WJ | Gene cloning and characterization of a novel esterase from activated sludge metagenome. | 2009 | Microb. Cell Fact. | pmid:20028524 |
| Li G et al. | Molecular cloning and characterization of a novel pyrethroid-hydrolyzing esterase originating from the Metagenome. | 2008 | Microb. Cell Fact. | pmid:19116015 |
| Glogauer A et al. | Identification and characterization of a new true lipase isolated through metagenomic approach. | 2011 | Microb. Cell Fact. | pmid:21762508 |
| Santala S et al. | Improved triacylglycerol production in Acinetobacter baylyi ADP1 by metabolic engineering. | 2011 | Microb. Cell Fact. | pmid:21592360 |
| Amaretti A et al. | Single cell oils of the cold-adapted oleaginous yeast Rhodotorula glacialis DBVPG 4785. | 2010 | Microb. Cell Fact. | pmid:20863365 |
| Peng Q et al. | A novel esterase gene cloned from a metagenomic library from neritic sediments of the South China Sea. | 2011 | Microb. Cell Fact. | pmid:22067554 |
| Yu WL et al. | Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae. | 2011 | Microb. Cell Fact. | pmid:22047615 |
| Fan X et al. | Identification and characterization of a novel thermostable pyrethroid-hydrolyzing enzyme isolated through metagenomic approach. | 2012 | Microb. Cell Fact. | pmid:22409882 |
| Ushijima T et al. | Selective and differential media for isolation and tentative identification of each species of Pityrosporum residing on normal or diseased human skin. | 1981 | Microbiol. Immunol. | pmid:7329340 |
| Yamashita S et al. | Identification of self-growth-inhibiting compounds lauric acid and 7-(Z)-tetradecenoic acid from Helicobacter pylori. | 2015 | Microbiology (Reading, Engl.) | pmid:25767109 |
| Geissdörfer W et al. | Two genes encoding proteins with similarities to rubredoxin and rubredoxin reductase are required for conversion of dodecane to lauric acid in Acinetobacter calcoaceticus ADP1. | 1995 | Microbiology (Reading, Engl.) | pmid:7670642 |
| Lamikanra A and Sholola OA | A study of the activity of soft soaps prepared from a homologous series of saturated fatty acids against cells of Escherichia coli NCTC 9001. | 1984 | Microbios | pmid:6397680 |
| Dmitriev VV et al. | [Yeasts utilizing the surface-active substance Laurox-9]. | 1988 Mar-Apr | Mikrobiologiia | pmid:3419368 |
| Kwan JC et al. | Lyngbyoic acid, a "tagged" fatty acid from a marine cyanobacterium, disrupts quorum sensing in Pseudomonas aeruginosa. | 2011 | Mol Biosyst | pmid:21258753 |
| Hand KV et al. | Acute and chronic effects of dietary fatty acids on cholecystokinin expression, storage and secretion in enteroendocrine STC-1 cells. | 2010 | Mol Nutr Food Res | pmid:20352619 |
| Morita YS and Englund PT | Fatty acid remodeling of glycosyl phosphatidylinositol anchors in Trypanosoma brucei: incorporation of fatty acids other than myristate. | 2001 | Mol. Biochem. Parasitol. | pmid:11420102 |
| van Roermund CW et al. | Identification of a peroxisomal ATP carrier required for medium-chain fatty acid beta-oxidation and normal peroxisome proliferation in Saccharomyces cerevisiae. | 2001 | Mol. Cell. Biol. | pmid:11390660 |
| Ellis CD et al. | The Neisseria gonorrhoeae lpxLII gene encodes for a late-functioning lauroyl acyl transferase, and a null mutation within the gene has a significant effect on the induction of acute inflammatory responses. | 2001 | Mol. Microbiol. | pmid:11679076 |
| Hankins JV et al. | Elucidation of a novel Vibrio cholerae lipid A secondary hydroxy-acyltransferase and its role in innate immune recognition. | 2011 | Mol. Microbiol. | pmid:21752109 |
| Wilhelmus MM et al. | Heat shock proteins and amateur chaperones in amyloid-Beta accumulation and clearance in Alzheimer's disease. | 2007 | Mol. Neurobiol. | pmid:17917109 |
| Besheer A et al. | Characterization of PLGA nanospheres stabilized with amphiphilic polymers: hydrophobically modified hydroxyethyl starch vs pluronics. | Mol. Pharm. | pmid:19718794 | |
| Halpert J et al. | Isozyme selectivity of the inhibition of rat liver cytochromes P-450 by chloramphenicol in vivo. | 1985 | Mol. Pharmacol. | pmid:4033629 |
| Dickmann LJ et al. | Identification and functional characterization of a new CYP2C9 variant (CYP2C9*5) expressed among African Americans. | 2001 | Mol. Pharmacol. | pmid:11455026 |
| Huang S et al. | Inhibition of Nod2 signaling and target gene expression by curcumin. | 2008 | Mol. Pharmacol. | pmid:18413660 |