lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

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Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Albuminuria D000419 18 associated lipids
Brain Infarction D020520 17 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Vasculitis D014657 14 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Obesity, Morbid D009767 8 associated lipids
Peripheral Arterial Disease D058729 7 associated lipids
Cerebral Infarction D002544 6 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

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Per page 10 20 50 100 | Total 1837
Authors Title Published Journal PubMed Link
Tenma T et al. Development of new lipophilic derivatives of tetragastrin: physicochemical characteristics and intestinal absorption of acyl-tetragastrin derivatives in rats. 1993 Pharm. Res. pmid:8272412
Smith SW and Anderson BD Salt and mesophase formation in aqueous suspensions of lauric acid. 1993 Pharm. Res. pmid:8272419
Yasuda H et al. An animal model of chronic ischemic neuropathy with proliferative changes of nerve microvessel wall. 1993 J. Neurol. Sci. pmid:8289080
Pinot F et al. New cytochrome P450-dependent reactions from wheat: terminal and sub-terminal hydroxylation of oleic acid by microsomes from naphthalic acid anhydride and phenobarbital induced wheat seedlings. 1994 Biochem. Biophys. Res. Commun. pmid:8297392
Tholstrup T et al. Fat high in stearic acid favorably affects blood lipids and factor VII coagulant activity in comparison with fats high in palmitic acid or high in myristic and lauric acids. 1994 Am. J. Clin. Nutr. pmid:8310987
Goldberg ML and Enig MG Palmitic and lauric acids and serum cholesterol. 1993 Am. J. Clin. Nutr. pmid:8338054
Orlowski M et al. Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids. 1993 Biochemistry pmid:8431436
Mustad VA et al. Comparison of the effects of diets rich in stearic acid versus myristic acid and lauric acid on platelet fatty acids and excretion of thromboxane A2 and PGI2 metabolites in healthy young men. 1993 Metab. Clin. Exp. pmid:8487669
Sawamura A et al. Catalytic properties of rabbit kidney fatty acid omega-hydroxylase cytochrome P-450ka2 (CYP4A7). 1993 Biochim. Biophys. Acta pmid:8504139
Niederprüm HJ et al. Inhibition of steroid 5 alpha-reductase activity by aliphatic fatty acids. Candidates for chemoprevention of prostate cancer. 1995 Ann. N. Y. Acad. Sci. pmid:8526353
Valdes E et al. Dietary fish oil and cytochrome P-450 monooxygenase activity in rat liver and kidney. 1995 Lipids pmid:8538384
Lapshina EA et al. Effect of free fatty acids on the structure and properties of erythrocyte membrane. 1995 Scand. J. Clin. Lab. Invest. pmid:8545597
Mabrey S and Sturtevant JM Incorporation of saturated fatty acids into phosphatidylcholine bilayers. 1977 Biochim. Biophys. Acta pmid:856286
Bambal RB and Hanzlik RP Active site structure and substrate specificity of cytochrome P450 4A1: steric control of ligand approach perpendicular to heme plane. 1996 Biochem. Biophys. Res. Commun. pmid:8605007
Pronczuk A et al. Plasma lipids are affected similarly by dietary lauric or palmitic acid in gerbils and monkeys. 1995 Lipids pmid:8614307
Amet Y et al. Validation of the (omega-1)-hydroxylation of lauric acid as an in vitro substrate probe for human liver CYP2E1. 1995 Biochem. Pharmacol. pmid:8615855
Temme EH et al. Comparison of the effects of diets enriched in lauric, palmitic, or oleic acids on serum lipids and lipoproteins in healthy women and men. 1996 Am. J. Clin. Nutr. pmid:8644684
Shet Ms et al. The omega-hydroxlyation of lauric acid: oxidation of 12-hydroxlauric acid to dodecanedioic acid by a purified recombinant fusion protein containing P450 4A1 and NADPH-P450 reductase. 1996 Arch. Biochem. Biophys. pmid:8651697
Narayanan VS and Storch J Fatty acid transfer in taurodeoxycholate mixed micelles. 1996 Biochemistry pmid:8652524
Castle PJ et al. Human liver lauric acid hydroxylase activities. 1995 Drug Metab. Dispos. pmid:8654190