lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

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Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Obesity, Morbid D009767 8 associated lipids
Prostatic Hyperplasia D011470 20 associated lipids
Seizures D012640 87 associated lipids
Starvation D013217 47 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Thrombosis D013927 49 associated lipids
Vasculitis D014657 14 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Brain Infarction D020520 17 associated lipids
Stroke D020521 32 associated lipids
Per page 10 20 50 | Total 33

PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

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What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

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Per page 10 20 50 100 | Total 1837
Authors Title Published Journal PubMed Link
Sawaguchi T and Nishida H Fatty liver in sudden infant death autopsies. 1998 Am J Forensic Med Pathol pmid:9760100
Zimmer T et al. Mutual conversion of fatty-acid substrate specificity by a single amino-acid exchange at position 527 in P-450Cm2 and P-450Alk3A. 1998 Eur. J. Biochem. pmid:9760180
Grinberg F et al. A new formalism for the evaluation of order-fluctuation modes in liquid crystals from field-cycling NMR-relaxometry data. 1998 J. Magn. Reson. pmid:9799675
Temme EH et al. Individual saturated fatty acids and effects on whole blood aggregation in vitro. 1998 Eur J Clin Nutr pmid:9805214
Guan X et al. Cytochrome P450-dependent desaturation of lauric acid: isoform selectivity and mechanism of formation of 11-dodecenoic acid. 1998 Chem. Biol. Interact. pmid:9566728
Miura Y and Oda S Oxidation of fatty acids by kidney microsomes of musk shrew (Suncus murinus). 1998 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:9530812
Amet Y et al. P-450-dependent metabolism of lauric acid in alcoholic liver disease: comparison between rat liver and kidney microsomes. 1998 Alcohol. Clin. Exp. Res. pmid:9581653
Bardi L et al. Saccharomyces cerevisiae cell fatty acid composition and release during fermentation without aeration and in absence of exogenous lipids. 1999 Int. J. Food Microbiol. pmid:10357281
NTP Toxicology and Carcinogenesis Studies of Lauric Acid Diethanolamine Condensate (CAS NO. 120-40-1) in F344/N Rats and B6C3F1 Mice (Dermal Studies). 1999 Natl Toxicol Program Tech Rep Ser pmid:12571683
Tsai YH et al. Mechanisms mediating lipoprotein responses to diets with medium-chain triglyceride and lauric acid. 1999 Lipids pmid:10574653
Cazeils JL et al. Lipid composition of hepatocyte plasma membranes from geese overfed with corn. 1999 Lipids pmid:10574658
Imaishi H et al. Encoding of a cytochrome P450-dependent lauric acid monooxygenase by CYP703A1 specifically expressed in the floral buds of petunia hybrida. 1999 Biosci. Biotechnol. Biochem. pmid:10664841
Glasgow BJ et al. Tear lipocalins: potential lipid scavengers for the corneal surface. 1999 Invest. Ophthalmol. Vis. Sci. pmid:10586930
Sabourault C et al. Tissue-specific induction and inactivation of cytochrome P450 catalysing lauric acid hydroxylation in the sea bass, Dicentrarchus labrax. 1999 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:10327614
Yamazaki H and Shimada T Effects of arachidonic acid, prostaglandins, retinol, retinoic acid and cholecalciferol on xenobiotic oxidations catalysed by human cytochrome P450 enzymes. 1999 Xenobiotica pmid:10219964
Murakami K et al. Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha. 1999 Biochem. Biophys. Res. Commun. pmid:10403814
Temme EH et al. Effects of diets enriched in lauric, palmitic or oleic acids on blood coagulation and fibrinolysis. 1999 Thromb. Haemost. pmid:10064003
Robinson MK et al. A two-center study of the development of acute irritation responses to fatty acids. 1999 Am. J. Contact Dermatitis pmid:10444106
Crawford TO et al. Abnormal fatty acid metabolism in childhood spinal muscular atrophy. 1999 Ann. Neurol. pmid:10072048
Haining RL et al. Enzymatic determinants of the substrate specificity of CYP2C9: role of B'-C loop residues in providing the pi-stacking anchor site for warfarin binding. 1999 Biochemistry pmid:10079071
Chang YT and Loew GH Homology modeling and substrate binding study of human CYP4A11 enzyme. 1999 Proteins pmid:10024026
Lagrost L et al. Variations in serum cholesteryl ester transfer and phospholipid transfer activities in healthy women and men consuming diets enriched in lauric, palmitic or oleic acids. 1999 Atherosclerosis pmid:10030391
Richieri GV et al. Binding kinetics of engineered mutants provide insight about the pathway for entering and exiting the intestinal fatty acid binding protein. 1999 Biochemistry pmid:10231541
Goodfriend TL et al. Plasma aldosterone, plasma lipoproteins, obesity and insulin resistance in humans. 1999 May-Jun Prostaglandins Leukot. Essent. Fatty Acids pmid:10471129
Gross V et al. Inhibition of pressure natriuresis in mice lacking the AT2 receptor. 2000 Kidney Int. pmid:10620200
Hoch U et al. Structural determination of the substrate specificities and regioselectivities of the rat and human fatty acid omega-hydroxylases. 2000 Arch. Biochem. Biophys. pmid:10620324
Aussel L et al. Novel variation of lipid A structures in strains of different Yersinia species. 2000 FEBS Lett. pmid:10620712
Nakagawa T et al. Peroxisomal membrane protein Pmp47 is essential in the metabolism of middle-chain fatty acid in yeast peroxisomes and Is associated with peroxisome proliferation. 2000 J. Biol. Chem. pmid:10652339
Soetanto K and Chan M Study on the lifetime and attenuation properties of microbubbles coated with carboxylic acid salts. 2000 Ultrasonics pmid:11106009
Loughran PA et al. Identification of unique amino acids that modulate CYP4A7 activity. 2000 Biochemistry pmid:11106489
Yang YH et al. Heterologous expression of CYP2K1 and identification of the expressed protein (BV-CYP2K1) as lauric acid (omega-1)-hydroxylase and aflatoxin B1 exo-epoxidase. 2000 Drug Metab. Dispos. pmid:11038153
Hashemi E et al. Stability of cytochrome P450 proteins in cultured precision-cut rat liver slices. 2000 Toxicology pmid:10967402
Giorgi M et al. Cytochrome P450-dependent monooxygenase activities and their inducibility by classic P450 inducers in the liver, kidney, and nasal mucosa of male adult ring-necked pheasants. 2000 Toxicol. Appl. Pharmacol. pmid:10986015
Imaishi H et al. CYP78A1 preferentially expressed in developing inflorescences of Zea mays encoded a cytochrome P450-dependent lauric acid 12-monooxygenase. 2000 Biosci. Biotechnol. Biochem. pmid:10993158
Nielsen AD et al. Thermochemistry of the specific binding of C12 surfactants to bovine serum albumin. 2000 Biochim. Biophys. Acta pmid:11004550
DeLany JP et al. Differential oxidation of individual dietary fatty acids in humans. 2000 Am. J. Clin. Nutr. pmid:11010930
Saffert A et al. A dual function alpha-dioxygenase-peroxidase and NAD(+) oxidoreductase active enzyme from germinating pea rationalizing alpha-oxidation of fatty acids in plants. 2000 Plant Physiol. pmid:10938370
Toshima Y et al. A new model of cerebral microthrombosis in rats and the neuroprotective effect of a Rho-kinase inhibitor. 2000 Stroke pmid:10978059
Santoyo S and Ygartua P Effect of skin pretreatment with fatty acids on percutaneous absorption and skin retention of piroxicam after its topical application. 2000 Eur J Pharm Biopharm pmid:10962234
Ohk SH and Kuramitsu HK A novel antibacterial agent derived from the C-terminal domain of streptococcus mutans GTP-binding protein. 2000 J. Antimicrob. Chemother. pmid:10882696
Kawashima H et al. Human fatty acid omega-hydroxylase, CYP4A11: determination of complete genomic sequence and characterization of purified recombinant protein. 2000 Arch. Biochem. Biophys. pmid:10860550
Hoch U et al. Molecular basis for the omega-regiospecificity of the CYP4A2 and CYP4A3 fatty acid hydroxylases. 2000 J. Biol. Chem. pmid:10869363
Kamm W et al. Evaluation of absorption enhancement for a potent cyclopeptidic alpha(nu)beta(3)-antagonist in a human intestinal cell line (Caco-2). 2000 Eur J Pharm Sci pmid:10767598
Sidhu SS et al. Fatty acid-induced cholecystokinin secretion and changes in intracellular Ca2+ in two enteroendocrine cell lines, STC-1 and GLUTag. 2000 J. Physiol. (Lond.) pmid:11018115
Wiberg E et al. The distribution of caprylate, caprate and laurate in lipids from developing and mature seeds of transgenic Brassica napus L. 2000 Planta pmid:11219581
Abigor RD et al. Lipase-catalysed production of biodiesel fuel from some Nigerian lauric oils. 2000 Biochem. Soc. Trans. pmid:11171279
Ngo S et al. Cytochrome P450 4A, peroxisomal enzymes and nicotinamide cofactors in koala liver. 2000 Comp. Biochem. Physiol. C Toxicol. Pharmacol. pmid:11246504
Kwok CS et al. Surface modification of polymers with self-assembled molecular structures: multitechnique surface characterization. 2000 Biomacromolecules pmid:11709836
Amet Y et al. Adaptation to chronic ethanol administration emphasized by fatty acid hydroxylations in rat liver and kidney microsomes. 2000 Eur J Nutr pmid:11395987
Kikuta Y et al. Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14. 2000 Arch. Biochem. Biophys. pmid:11185557