lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

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Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Hypersensitivity, Delayed D006968 43 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hemolysis D006461 131 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Cerebral Infarction D002544 6 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 50 | Total 33

PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

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Per page 10 20 50 100 | Total 1837
Authors Title Published Journal PubMed Link
Quilichini TD et al. ATP-binding cassette transporter G26 is required for male fertility and pollen exine formation in Arabidopsis. 2010 Plant Physiol. pmid:20732973
Dobritsa AA et al. LAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis. 2010 Plant Physiol. pmid:20442277
Larson TR and Graham IA Technical Advance: a novel technique for the sensitive quantification of acyl CoA esters from plant tissues. 2001 Plant J. pmid:11169187
Koo AJ et al. Identification of a plastid acyl-acyl carrier protein synthetase in Arabidopsis and its role in the activation and elongation of exogenous fatty acids. 2005 Plant J. pmid:16262711
Lekshmi Sheela D et al. In Silico and Wet Lab Studies Reveal the Cholesterol Lowering Efficacy of Lauric Acid, a Medium Chain Fat of Coconut Oil. 2016 Plant Foods Hum Nutr pmid:27679437
Suzuki T et al. Identification of kaonashi mutants showing abnormal pollen exine structure in Arabidopsis thaliana. 2008 Plant Cell Physiol. pmid:18779216
Grausem B et al. CYP77A19 and CYP77A20 characterized from Solanum tuberosum oxidize fatty acids in vitro and partially restore the wild phenotype in an Arabidopsis thaliana cutin mutant. 2014 Plant Cell Environ. pmid:24520956
Li H et al. Cytochrome P450 family member CYP704B2 catalyzes the {omega}-hydroxylation of fatty acids and is required for anther cutin biosynthesis and pollen exine formation in rice. 2010 Plant Cell pmid:20086189
Xu J et al. The ABORTED MICROSPORES regulatory network is required for postmeiotic male reproductive development in Arabidopsis thaliana. 2010 Plant Cell pmid:20118226
Morant M et al. CYP703 is an ancient cytochrome P450 in land plants catalyzing in-chain hydroxylation of lauric acid to provide building blocks for sporopollenin synthesis in pollen. 2007 Plant Cell pmid:17496121
Kim SS et al. LAP6/POLYKETIDE SYNTHASE A and LAP5/POLYKETIDE SYNTHASE B encode hydroxyalkyl α-pyrone synthases required for pollen development and sporopollenin biosynthesis in Arabidopsis thaliana. 2010 Plant Cell pmid:21193570
Renard-Merlier D et al. Changes in C12:0, C18:1, C18:2 and C20:2 fatty acid content in wheat treated with resistance inducers and infected by powdery mildew. 2009 Plant Biol (Stuttg) pmid:19121116
Nischwitz C et al. Use of Fatty Acid Methyl Ester Profiles to Compare Copper-Tolerant and Copper-Sensitive Strains of Pantoea ananatis. 2007 Phytopathology pmid:18943688
Kadu CA et al. Bioactive constituents in Prunus africana: geographical variation throughout Africa and associations with environmental and genetic parameters. 2012 Phytochemistry pmid:22795601
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Afitlhile MM et al. Labeling of major plant lipids and jasmonic acid using [1-(14C)] lauric acid. 2004 Phytochemistry pmid:15464155
Mo FF et al. Acute hyperglycemia is related to gastrointestinal symptoms in motion sickness: an experimental study. 2012 Physiol. Behav. pmid:21907224
Mattern HM and Hardin CD Vascular metabolic dysfunction and lipotoxicity. 2007 Physiol Res pmid:16555946
Skottová N et al. Effect of premature weaning on the fatty acid composition of rat adipose tissue. 1977 Physiol Bohemoslov pmid:140394
Pereira JR et al. Inversion in the change of the refractive index and memory effect near the nematic-isotropic phase transition in a lyotropic liquid crystal. 2000 Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics pmid:11031592