| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Cerebrovascular Disorders | D002561 | 25 associated lipids |
| Cerebral Infarction | D002544 | 6 associated lipids |
| Cell Transformation, Viral | D002472 | 26 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
lauric acid
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
Cross Reference
Introduction
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with lauric acid?
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with lauric acid
PubChem Associated disorders and diseases
What pathways are associated with lauric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with lauric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with lauric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with lauric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with lauric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with lauric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with lauric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lu Y et al. | Impedance spectroscopy analysis of human odorant binding proteins immobilized on nanopore arrays for biochemical detection. | 2016 | Biosens Bioelectron | pmid:26710343 |
| Zhang W et al. | Enhanced physicochemical properties of chitosan/whey protein isolate composite film by sodium laurate-modified TiO2 nanoparticles. | 2016 | Carbohydr Polym | pmid:26794738 |
| Imai Y et al. | Structure-function relationships of cytochrome P-450 laurate (omega-1)-hydroxylase. | 1989 | Drug Metab. Rev. | pmid:2680391 |
| Uno T and Imai Y | Identification of regions functioning in substrate interaction of rabbit liver cytochrome P-450 (laurate (omega-1)-hydroxylase). | 1989 | J. Biochem. | pmid:2691506 |
| Rincón-Pérez J et al. | Fatty Acids Profile, Phenolic Compounds and Antioxidant Capacity in Elicited Callus of Thevetia peruviana (Pers.) K. Schum. | 2016 | J Oleo Sci | pmid:26972464 |
| Hong Y et al. | Photothermal ablation of cancer cells using self-doped polyaniline nanoparticles. | 2016 | Nanotechnology | pmid:27010331 |
| Stucki JW et al. | Acylation of proteins by myristic acid in isolated mitochondria. | 1989 | J. Biol. Chem. | pmid:2703494 |
| Weissenborn MJ et al. | Whole-cell microtiter plate screening assay for terminal hydroxylation of fatty acids by P450s. | 2016 | Chem. Commun. (Camb.) | pmid:27074906 |
| Cerchiara T et al. | Microparticles based on chitosan/carboxymethylcellulose polyelectrolyte complexes for colon delivery of vancomycin. | 2016 | Carbohydr Polym | pmid:27083351 |
| Kupetz M et al. | Impact of flavouring substances on the aggregation behaviour of dissolved barley β-glucans in a model beer. | 2016 | Carbohydr Polym | pmid:27083361 |
| Frolov AF et al. | Fatty acid composition of lipopolysaccharides of the strains of different species of Yersinia. | 1989 | J Hyg Epidemiol Microbiol Immunol | pmid:2723424 |
| Gyawali P et al. | Determination of Ancylostoma caninum ova viability using metabolic profiling. | 2016 | Parasitol. Res. | pmid:27236650 |
| Ryals PE et al. | Lipid modification during cytodifferentiation of Tetrahymena vorax. Whole cell phospholipids and triacylglycerols of microstomal and macrostomal phenotypes. | 1989 | Biochim. Biophys. Acta | pmid:2730920 |
| Karahaliloglu Z et al. | Antibacterial chitosan/silk sericin 3D porous scaffolds as a wound dressing material. | 2017 | Artif Cells Nanomed Biotechnol | pmid:27396677 |
| Holdfeldt A et al. | The Lipidated Peptidomimetic Lau-((S)-Aoc)-(Lys-βNphe)6-NH2 Is a Novel Formyl Peptide Receptor 2 Agonist That Activates Both Human and Mouse Neutrophil NADPH Oxidase. | 2016 | J. Biol. Chem. | pmid:27422818 |
| Nonaka Y et al. | Lauric Acid Stimulates Ketone Body Production in the KT-5 Astrocyte Cell Line. | 2016 | J Oleo Sci | pmid:27430387 |
| Dhers L et al. | Spectral and 3D model studies of the interaction of orphan human cytochrome P450 2U1 with substrates and ligands. | 2017 | Biochim Biophys Acta Gen Subj | pmid:27456766 |
| Huo Q et al. | Molecular modification of proanthocyanidins. | 2016 | Bioengineered | pmid:27459598 |
| Ohhira S and Matsui H | [Determination of dibutyltin compounds in polyvinyl chloride resin by capillary gas chromatography]. | 1989 | Nihon Eiseigaku Zasshi | pmid:2746975 |
| Gawas SD et al. | Solvent Free Lipase Catalysed Synthesis of Ethyl Laurate: Optimization and Kinetic Studies. | 2016 | Appl. Biochem. Biotechnol. | pmid:27470112 |
| Yuan Y et al. | Coupling electrokinetics with microbial biodegradation enhances the removal of cycloparaffinic hydrocarbons in soils. | 2016 | J. Hazard. Mater. | pmid:27501882 |
| Christensen E et al. | Beta-oxidation of medium chain (C8-C14) fatty acids studied in isolated liver cells. | 1989 | Biochim. Biophys. Acta | pmid:2752017 |
| Wada M et al. | Mechanism of biosynthesis of unsaturated fatty acids in Pseudomonas sp. strain E-3, a psychrotrophic bacterium. | 1989 | J. Bacteriol. | pmid:2753856 |
| Bugaut M | In vivo incorporation of lauric acid into rat adipose tissue triacylglycerols. | 1989 | Lipids | pmid:2761351 |
| Tambo F et al. | Auto-oxidation of Lingula unguis and Siphonosoma cumanense hemerythrins induced by some perturbants. | 1989 | Biochem. Int. | pmid:2764951 |
| Lekshmi Sheela D et al. | In Silico and Wet Lab Studies Reveal the Cholesterol Lowering Efficacy of Lauric Acid, a Medium Chain Fat of Coconut Oil. | 2016 | Plant Foods Hum Nutr | pmid:27679437 |
| Kojima K et al. | A simple method for isolation and construction of markerless cyanobacterial mutants defective in acyl-acyl carrier protein synthetase. | 2016 | Appl. Microbiol. Biotechnol. | pmid:27704180 |
| Youngquist JT et al. | Functional genomics analysis of free fatty acid production under continuous phosphate limiting conditions. | 2017 | J. Ind. Microbiol. Biotechnol. | pmid:27738839 |
| Zhang L et al. | Degradation Mechanisms of Polysorbate 20 Differentiated by O-labeling and Mass Spectrometry. | 2017 | Pharm. Res. | pmid:27738952 |
| Sharma RK et al. | Differential induction of peroxisomal and microsomal fatty-acid-oxidising enzymes by peroxisome proliferators in rat liver and kidney. Characterisation of a renal cytochrome P-450 and implications for peroxisome proliferation. | 1989 | Eur. J. Biochem. | pmid:2776771 |
| Han S et al. | Structural insights into the binding of lauric acid to CYP107L2 from Streptomyces avermitilis. | 2017 | Biochem. Biophys. Res. Commun. | pmid:27890614 |
| Albertini B et al. | A novel approach for dry powder coating of pellets with Ethylcellulose. Part I: Evaluation of film formulation and process set up. | 2017 | Int J Pharm | pmid:27894987 |
| Beyer N et al. | P450 fused to phosphite dehydrogenase allows phosphite-driven selective oxidations. | 2017 | Appl. Microbiol. Biotechnol. | pmid:27900443 |
| Green PG et al. | Enhanced in vitro skin permeation of cationic drugs. | 1989 | Pharm. Res. | pmid:2798314 |
| Alves NF et al. | Acute Treatment with Lauric Acid Reduces Blood Pressure and Oxidative Stress in Spontaneously Hypertensive Rats. | 2017 | Basic Clin. Pharmacol. Toxicol. | pmid:28054477 |
| Sato H et al. | Multiple binding of bilirubin to human serum albumin and cobinding with laurate. | 1988 | Arch. Biochem. Biophys. | pmid:2829743 |
| Ruiz MB et al. | Cholesterol ester hydrolysis in isolated rat liver cells. Effect of estradiol, dibutyryl cyclic AMP and free fatty acids. | 1988 | Horm. Metab. Res. | pmid:2836287 |
| Dev Kumar G and Micallef SA | Susceptibility of Salmonella enterica Isolates from Tomato Farm Environments to Fatty Acids Naturally Found on Tomato Fruit. | 2017 | Foodborne Pathog. Dis. | pmid:28398868 |
| Magdalou J et al. | Effect of 1-benzylimidazole on cytochromes P-450 induction and on the activities of epoxide hydrolases and UDP-glucuronosyltransferases in rat liver. | 1988 | Biochem. Pharmacol. | pmid:2840913 |
| Zeiger K et al. | Lauric acid as feed additive - An approach to reducing Campylobacter spp. in broiler meat. | 2017 | PLoS ONE | pmid:28419122 |
| Tanaka T et al. | Activation by saturated and monounsaturated fatty acids of the O2- -generating system in a cell-free preparation from neutrophils. | 1988 | J. Biol. Chem. | pmid:2843528 |
| Dahlbäck H and Wikvall K | 25-Hydroxylation of vitamin D3 by a cytochrome P-450 from rabbit liver mitochondria. | 1988 | Biochem. J. | pmid:2844144 |
| Poller JM et al. | Selection of potential iron oxide nanoparticles for breast cancer treatment based on in vitro cytotoxicity and cellular uptake. | 2017 | Int J Nanomedicine | pmid:28458541 |
| Anis SNS et al. | In vivo and in vitro depolymerizations of intracellular medium-chain-length poly-3-hydroxyalkanoates produced by Pseudomonas putida Bet001. | 2017 | Prep. Biochem. Biotechnol. | pmid:28635367 |
| Miura Y | Seasonal change and sex difference in laurate hydroxylase activity in frog liver microsomes. | 1985 | Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. | pmid:2865076 |
| Raza H and Levine WG | Azoreduction of N,N-dimethyl-4-aminoazobenzene (DAB) by rat hepatic microsomes. Selective induction by clofibrate. | 1986 Jan-Feb | Drug Metab. Dispos. | pmid:2868860 |
| Yi M et al. | Expression of CYP4V2 in human THP1 macrophages and its transcriptional regulation by peroxisome proliferator-activated receptor gamma. | 2017 | Toxicol. Appl. Pharmacol. | pmid:28729181 |
| Harsfalvi J et al. | Lipids associated with tissue transglutaminase. | 1987 | Biochim. Biophys. Acta | pmid:2879570 |
| Fournel S et al. | Differential induction profile of drug-metabolizing enzymes after treatment with hypolipidaemic agents. | 1987 | Xenobiotica | pmid:2885979 |
| Alam MS et al. | Influence of di-butyltin dilaurate on brain neurotransmitter systems and behavior in rats. | 1988 | Arch. Toxicol. | pmid:2899427 |
| Levine WG and Raza H | Mechanism of azoreduction of dimethylaminoazobenzene by rat liver NADPH-cytochrome P-450 reductase and partially purified cytochrome P-450. Oxygen and carbon monoxide sensitivity and stimulation by FAD and FMN. | 1988 May-Jun | Drug Metab. Dispos. | pmid:2900738 |
| Muerhoff AS et al. | Prostaglandin and fatty acid omega- and (omega-1)-oxidation in rabbit lung. Acetylenic fatty acid mechanism-based inactivators as specific inhibitors. | 1989 | J. Biol. Chem. | pmid:2910864 |
| Khan S et al. | Effect of a Prudhoe Bay crude oil on hepatic and renal peroxisomal beta-oxidation and mixed-function oxidase activities in rats. | 1989 | Carcinogenesis | pmid:2912577 |
| Cometti A et al. | Isolation and structure determination of the main related substances of teicoplanin, a glycopeptide antibiotic. | 1988 | Farmaco Sci | pmid:2977757 |
| Dailey MO et al. | Induction of cell-mediated immunity to chemically modified antigens in guinea pigs. II. The interaction between lipid-conjugated antigens, macrophages, and T lymphocytes. | 1977 | J. Immunol. | pmid:300393 |
| Romano MC et al. | Biochemical characterization of hepatic microsomal leukotriene B4 hydroxylases. | 1987 | J. Biol. Chem. | pmid:3027095 |
| Tanaka T et al. | Saturated and trans-unsaturated fatty acids elicit high levels of superoxide generation in intact and cell-free preparations of neutrophils. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3034258 |
| Miura Y | Effects of in vivo administration of detergents on the hepatic microsomal cytochrome P-450 system in rat. | 1987 | J Appl Toxicol | pmid:3040845 |
| Gergely J | [S. Tonegawa, 1987 Nobel Prize laureate in medicine]. | 1988 | Orv Hetil | pmid:3050756 |
| Lehmann V and Benninghoff B | Isolation of a mutant from Salmonella typhimurium producing acyl-deficient lipopolysaccharides. | 1988 | Eur. J. Biochem. | pmid:3061817 |
| Fournel S et al. | Stereospecific induction of rat liver bilirubin UDPglucuronosyltransferase and lauric acid 12-hydroxylation by the isomers of 2-phenylpropionic acid. | 1986 | Biochim. Biophys. Acta | pmid:3089296 |
| Ohashi M et al. | Anti-thrombotic effect of KC-404, a novel cerebral vasodilator. | 1986 | Gen. Pharmacol. | pmid:3093313 |
| Levine WG and Raza H | Clofibrate selectively induces azoreduction of dimethylaminoazobenzene (DAB) by rat liver microsomes. | 1986 | Adv. Exp. Med. Biol. | pmid:3094343 |
| Miura Y et al. | omega- and (omega--1)-hydroxylation of fatty acids by frog liver microsomes. Substrate specificity and other properties. | 1978 | Biochim. Biophys. Acta | pmid:309772 |
| Raza H and Levine WG | Effect of hypolipidemic drugs on the metabolism of lauric acid and dimethylaminoazobenzene by rat liver microsomes. | 1987 | Biochem. Pharmacol. | pmid:3103631 |
| Rose RC | Solubility properties of reduced and oxidized ascorbate as determinants of membrane permeation. | 1987 | Biochim. Biophys. Acta | pmid:3103695 |
| Elcombe CR and Mitchell AM | Peroxisome proliferation due to di(2-ethylhexyl) phthalate (DEHP): species differences and possible mechanisms. | 1986 | Environ. Health Perspect. | pmid:3104023 |
| Leyton J et al. | Differential oxidation of saturated and unsaturated fatty acids in vivo in the rat. | 1987 | Br. J. Nutr. | pmid:3109464 |
| Fournel S et al. | Stereospecificity of enzyme induction by 2-phenylpropionic acid. | 1987 | Pharmacol. Ther. | pmid:3114776 |
| Albro PW et al. | Rapid isolation of microsomes for studies of lipid peroxidation. | 1987 | Lipids | pmid:3123838 |
| Sumimoto J et al. | Characterization of human neutrophil leukotriene B4 omega-hydroxylase as a system involving a unique cytochrome P-450 and NADPH-cytochrome P-450 reductase. | 1988 | Eur. J. Biochem. | pmid:3127205 |
| Eriksson LO and Boström H | Deactivation of sulindac-sulphide by human renal microsomes. | 1988 | Pharmacol. Toxicol. | pmid:3133648 |
| Imai Y and Nakamura M | The importance of threonine-301 from cytochromes P-450 (laurate (omega-1)-hydroxylase and testosterone 16 alpha-hydroxylase) in substrate binding as demonstrated by site-directed mutagenesis. | 1988 | FEBS Lett. | pmid:3134259 |
| Qureshi N et al. | Complete structural determination of lipopolysaccharide obtained from deep rough mutant of Escherichia coli. Purification by high performance liquid chromatography and direct analysis by plasma desorption mass spectrometry. | 1988 | J. Biol. Chem. | pmid:3136169 |
| Kiffel L et al. | Purification and characterization of a cytochrome P-450 isozyme isolated from the liver of rats pretreated with clofibrate. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3140811 |
| Donbrow M et al. | Autoxidation of polysorbates. | 1978 | J Pharm Sci | pmid:31449 |
| Honoré B et al. | Cobinding of bilirubin and laurate to human serum albumin: spectroscopic characterization of stoichiometric complexes. | 1988 | Arch. Biochem. Biophys. | pmid:3178221 |
| Csordas A and Rybczynska M | Critical temperatures for the interaction of free fatty acids with the erythrocyte membrane. | 1988 | Biochim. Biophys. Acta | pmid:3179287 |
| Andreiuk GM and Kiselev PA | [Initiation of lipid peroxidation as a result of hemoglobin transformation into hemichrome induced by free fatty acids]. | 1988 | Biokhimiia | pmid:3179347 |
| Lorenzana RM et al. | Localization of cytochrome P-450 in the head and trunk kidney of rainbow trout (Salmo gairdneri). | 1988 | Toxicol. Appl. Pharmacol. | pmid:3188021 |
| Goldberg M et al. | Enzymatic ester synthesis with continuous measurement of water activity. | 1988 | Biochim. Biophys. Acta | pmid:3196717 |
| CaJacob CA et al. | The catalytic site of rat hepatic lauric acid omega-hydroxylase. Protein versus prosthetic heme alkylation in the omega-hydroxylation of acetylenic fatty acids. | 1988 | J. Biol. Chem. | pmid:3198593 |
| Fibach E et al. | Flow cytofluorometric analysis of the uptake of the fluorescent fatty acid pyrene-dodecanoic acid by human peripheral blood cells. | 1988 | Cytometry | pmid:3208618 |
| Ikeda T et al. | Induction of peroxisome proliferation in rat liver by dietary treatment with 2,2,4,4,6,8,8-heptamethylnonane. | 1988 | Xenobiotica | pmid:3245225 |
| Imai Y | Characterization of rabbit liver cytochrome P-450 (laurate omega-1 hydroxylase) synthesized in transformed yeast cells. | 1988 | J. Biochem. | pmid:3283112 |
| Stanislawski L et al. | Hybridoma antibodies to the lipid-binding site(s) in the amino-terminal region of fibronectin inhibits binding of streptococcal lipoteichoic acid. | 1987 | J. Infect. Dis. | pmid:3298457 |
| Rietschel ET et al. | Chemical structure and biologic activity of bacterial and synthetic lipid A. | 1987 Sep-Oct | Rev. Infect. Dis. | pmid:3317748 |
| Salaün JP et al. | Differential inactivation of plant lauric acid omega- and in-chain-hydroxylases by terminally unsaturated fatty acids. | 1988 | Arch. Biochem. Biophys. | pmid:3341756 |
| Homan R and Pownall HJ | Transbilayer diffusion of phospholipids: dependence on headgroup structure and acyl chain length. | 1988 | Biochim. Biophys. Acta | pmid:3342229 |
| Sharma R et al. | Co-induction of microsomal cytochrome P-452 and the peroxisomal fatty acid beta-oxidation pathway in the rat by clofibrate and di-(2-ethylhexyl)phthalate. Dose-response studies. | 1988 | Biochem. Pharmacol. | pmid:3355594 |
| Imaoka S et al. | Induction of renal cytochrome P-450 in hepatic microsomes of diabetic rats. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3365247 |
| Roomi MW et al. | Decreased expression of cytochrome P-452 in the resistance phenotype characteristic of putative preneoplastic hepatocyte nodules during hepatocarcinogenesis. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3365259 |
| Bacher MA and Gibson GG | Chlorophenoxyacid herbicides induce microsomal cytochrome P-450 IVA1 (P-452) in rat liver. | 1988 | Chem. Biol. Interact. | pmid:3365825 |
| De Cuyper M and Joniau M | Magnetoliposomes. Formation and structural characterization. | 1988 | Eur. Biophys. J. | pmid:3366097 |
| Romano MC et al. | Determination of microsomal lauric acid hydroxylase activity by HPLC with flow-through radiochemical quantitation. | 1988 | Anal. Biochem. | pmid:3389520 |
| Pedersen AO and Brodersen R | Myristic acid binding to human serum albumin investigated by dialytic exchange rate. | 1988 | J. Biol. Chem. | pmid:3392011 |
| Zoeller RA et al. | A possible role for plasmalogens in protecting animal cells against photosensitized killing. | 1988 | J. Biol. Chem. | pmid:3403547 |
| Pazo JA and Parafita MA | Synergism of ethanol and clofibrate in the lauric acid hydroxylation. | 1988 | Drug Alcohol Depend | pmid:3416732 |
| Dmitriev VV et al. | [Yeasts utilizing the surface-active substance Laurox-9]. | 1988 Mar-Apr | Mikrobiologiia | pmid:3419368 |
| Whiting P and Dinan L | Formation of apolar ecdysteroid conjugates by ovaries of the house cricket Acheta domesticus in vitro. | 1988 | Biochem. J. | pmid:3421912 |