lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

Cross Reference

Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Hyperlipidemias D006949 73 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Albuminuria D000419 18 associated lipids
Vasculitis D014657 14 associated lipids
Atherosclerosis D050197 85 associated lipids
Peripheral Arterial Disease D058729 7 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Bird Diseases D001715 4 associated lipids
Obesity, Morbid D009767 8 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Per page 10 20 50 | Total 33

PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

Download all related citations
Per page 10 20 50 100 | Total 1837
Authors Title Published Journal PubMed Link
Hara H et al. Effect of (+/-)-2-(dimethylamino)-1-[[o-(m-methoxyphenethyl)phenoxy] methyl]ethyl hydrogen succinate on experimental models of peripheral obstructive disease. 1991 Arzneimittelforschung pmid:1930349
Idris CA and Sundram K Effect of dietary cholesterol, trans and saturated fatty acids on serum lipoproteins in non-human primates. 2002 Asia Pac J Clin Nutr pmid:12492627
Serra I et al. Effect of dietary intake on the levels of biliary unsaturated free Fatty acids having inhibitory activity on mutagens. 2009 Asian Pac. J. Cancer Prev. pmid:20104986
Hanley K et al. Development of a plant viral-vector-based gene expression assay for the screening of yeast cytochrome p450 monooxygenases. 2003 Assay Drug Dev Technol pmid:15090141
HÃ¥versen L et al. Induction of proinflammatory cytokines by long-chain saturated fatty acids in human macrophages. 2009 Atherosclerosis pmid:18599066
Yoshida H et al. A phosphodiesterase 3 inhibitor, K-134, improves hindlimb skeletal muscle circulation in rat models of peripheral arterial disease. 2012 Atherosclerosis pmid:22269153
Arrol S et al. The effects of fatty acids on apolipoprotein B secretion by human hepatoma cells (HEP G2). 2000 Atherosclerosis pmid:10856517
Redgrave TG and Dunne KB Chylomicron formation and composition in unanaesthetised rabbits. 1975 Nov-Dec Atherosclerosis pmid:173354
Lagrost L et al. Variations in serum cholesteryl ester transfer and phospholipid transfer activities in healthy women and men consuming diets enriched in lauric, palmitic or oleic acids. 1999 Atherosclerosis pmid:10030391
Timbermont L et al. Control of Clostridium perfringens-induced necrotic enteritis in broilers by target-released butyric acid, fatty acids and essential oils. 2010 Avian Pathol. pmid:20390546
Alves NF et al. Acute Treatment with Lauric Acid Reduces Blood Pressure and Oxidative Stress in Spontaneously Hypertensive Rats. 2017 Basic Clin. Pharmacol. Toxicol. pmid:28054477
Stark K et al. Expression of CYP4F12 in gastrointestinal and urogenital epithelia. 2004 Basic Clin. Pharmacol. Toxicol. pmid:15078342
Russell VA et al. Animal models of attention-deficit hyperactivity disorder. 2005 Behav Brain Funct pmid:16022733
Hu H et al. A novel class of antagonists for the FFAs receptor GPR40. 2009 Biochem. Biophys. Res. Commun. pmid:19818732
Bambal RB and Hanzlik RP Active site structure and substrate specificity of cytochrome P450 4A1: steric control of ligand approach perpendicular to heme plane. 1996 Biochem. Biophys. Res. Commun. pmid:8605007
Leighton F et al. Peroxisomal fatty acid oxidation is selectively inhibited by phenothiazines in isolated hepatocytes. 1984 Biochem. Biophys. Res. Commun. pmid:6732769
Okita R and Chance C Induction of laurate omega-hydroxylase by di (2-ethylhexyl)phthalate in rat liver microsomes. 1984 Biochem. Biophys. Res. Commun. pmid:6732809
Han S et al. Structural insights into the binding of lauric acid to CYP107L2 from Streptomyces avermitilis. 2017 Biochem. Biophys. Res. Commun. pmid:27890614
Kiffel L et al. Purification and characterization of a cytochrome P-450 isozyme isolated from the liver of rats pretreated with clofibrate. 1988 Biochem. Biophys. Res. Commun. pmid:3140811
Murakami K et al. Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha. 1999 Biochem. Biophys. Res. Commun. pmid:10403814