lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

Cross Reference

Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Hyperlipidemias D006949 73 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Albuminuria D000419 18 associated lipids
Vasculitis D014657 14 associated lipids
Atherosclerosis D050197 85 associated lipids
Peripheral Arterial Disease D058729 7 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Bird Diseases D001715 4 associated lipids
Obesity, Morbid D009767 8 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Per page 10 20 50 | Total 33

PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

Download all related citations
Per page 10 20 50 100 | Total 1837
Authors Title Published Journal PubMed Link
Li H et al. Phase transition in salt-free catanionic surfactant mixtures induced by temperature. 2010 Langmuir pmid:19810715
Zana R Partial phase behavior and micellar properties of tetrabutylammonium salts of fatty acids: unusual solubility in water and formation of unexpectedly small micelles. 2004 Langmuir pmid:16459576
Vlachy N et al. Spontaneous formation of bilayers and vesicles in mixtures of single-chain alkyl carboxylates: effect of pH and aging and cytotoxicity studies. 2008 Langmuir pmid:18712886
Kim JH et al. Evaporation of sessile droplets of dilute aqueous solutions containing sodium n-alkylates from polymer surfaces: influences of alkyl length and concentration of solute. 2008 Langmuir pmid:18798660
Nelson N et al. Single molecule dynamics on hydrophobic self-assembled monolayers. 2012 Langmuir pmid:22876990
Roux M et al. Dynamic lipid lateral segregation driven by lauryl cyclodextrin interactions at the membrane surface. 2013 Langmuir pmid:23409976
Totland C et al. Composition and structural transitions of polyelectrolyte-surfactant complexes in the presence of fatty acid studied by NMR and cryo-SEM. 2015 Langmuir pmid:25590530
Sagis LM et al. Highly stable foams from block oligomers synthesized by enzymatic reactions. 2008 Langmuir pmid:18081334
Steinmiller EM and Choi KS Anodic construction of lamellar structured ZnO films using basic media via interfacial surfactant templating. 2007 Langmuir pmid:17973505
Hidalgo Baltasar E et al. Role of water structure on the high pressure micellization and phase transformations of sodium dodecanoate aqueous solutions. 2014 Langmuir pmid:24903603
Chernyshova IV et al. Adsorption of fatty acids on iron (hydr)oxides from aqueous solutions. 2011 Langmuir pmid:21711036
King DT et al. Using molecular dynamics to study liquid phase behavior: simulations of the ternary sodium laurate/sodium oleate/water system. 2011 Langmuir pmid:21838286
Li H et al. Reverse vesicles from a salt-free catanionic surfactant system: a confocal fluorescence microscopy study. 2010 Langmuir pmid:20822115
De Lisi R et al. Heat capacity of transfer of (Ethylene oxide)13-(propylene oxide)30-(ethylene oxide)13 from water to the aqueous anionic surfactant solutions at 298 K. A quantitative treatment. 2004 Langmuir pmid:15518478
Mahiuddin S et al. Catanionic micelles as a model to mimic biological membranes in the presence of anesthetic alcohols. 2009 Langmuir pmid:19856990
Nicolaas L et al. Patellofemoral evaluation with magnetic resonance imaging in 51 knees of asymptomatic subjects. 2011 Knee Surg Sports Traumatol Arthrosc pmid:21533540
Gross V et al. Inhibition of pressure natriuresis in mice lacking the AT2 receptor. 2000 Kidney Int. pmid:10620200
Ghiggeri GM et al. Characterization of cationic albumin in minimal change nephropathy. 1987 Kidney Int. pmid:3430951
Shirakura S et al. Antithrombotic effects of KW-3635, a thromboxane A2-receptor antagonist, in guinea pigs. 1994 Jpn. J. Pharmacol. pmid:7967232
Hasumura S et al. Effects of starvation on microsomal cytochrome P-450 and laurate-omega-hydroxylation of rat kidney and liver. 1983 Jpn. J. Pharmacol. pmid:6645119
Miura Y et al. An analysis of the fatty acid composition of total lipids from mycoplasmas. 1978 Jpn. J. Exp. Med. pmid:750678
Sigalet DL et al. Determination of the route of medium-chain and long-chain fatty acid absorption by direct measurement in the rat. 1997 Sep-Oct JPEN J Parenter Enteral Nutr pmid:9323689
Yoon JW and Hovde CJ All blood, no stool: enterohemorrhagic Escherichia coli O157:H7 infection. 2008 J. Vet. Sci. pmid:18716441
Mann RS and Kaufman PE Colonization of Lutzomyia shannoni (Diptera: Psychodidae) utilizing an artificial blood feeding technique. 2010 J. Vector Ecol. pmid:21175933
Kong X et al. High-mobility-group box protein 1A box reduces development of sodium laurate-induced thromboangiitis obliterans in rats. 2013 J. Vasc. Surg. pmid:23069071
Garfinkel M et al. Insulinotropic potency of lauric acid: a metabolic rationale for medium chain fatty acids (MCF) in TPN formulation. 1992 J. Surg. Res. pmid:1593871
Raynaud JP et al. Inhibition of type 1 and type 2 5alpha-reductase activity by free fatty acids, active ingredients of Permixon. 2002 J. Steroid Biochem. Mol. Biol. pmid:12477490
Coimbra MC and Jorge N Fatty acids and bioactive compounds of the pulps and kernels of Brazilian palm species, guariroba (Syagrus oleraces), jerivá (Syagrus romanzoffiana) and macaúba (Acrocomia aculeata). 2012 J. Sci. Food Agric. pmid:21922463
Blum JJ Effects of osmotic pressure on the oxidative metabolism of Leishmania major promastigotes. 1991 May-Jun J. Protozool. pmid:1679134
Wołkow PP and Korbut R Pharmacology at the Jagiellonian University in Kracow, short review of contribution to global science and cardiovascular research through 400 years of history. 2006 J. Physiol. Pharmacol. pmid:16766803
Sidhu SS et al. Fatty acid-induced cholecystokinin secretion and changes in intracellular Ca2+ in two enteroendocrine cell lines, STC-1 and GLUTag. 2000 J. Physiol. (Lond.) pmid:11018115
Feltrin KL et al. Effects of lauric acid on upper gut motility, plasma cholecystokinin and peptide YY, and energy intake are load, but not concentration, dependent in humans. 2007 J. Physiol. (Lond.) pmid:17331985
Benson RS et al. Fatty acid signalling in a mouse enteroendocrine cell line involves fatty acid aggregates rather than free fatty acids. 2002 J. Physiol. (Lond.) pmid:11773321
Kazmi S et al. Calcium mobilisation and CCK secretion induced by modified fatty acids and latex microspheres reveal dual receptor mechanisms for lipid stimulation of STC-1 cells. 2003 J. Physiol. (Lond.) pmid:14555726
Inami Y et al. Prevention of topical surfactant-induced itch-related responses by chlorogenic acid through the inhibition of increased histamine production in the epidermis. 2013 J. Pharmacol. Sci. pmid:23449492
Lindmark T et al. Absorption enhancement through intracellular regulation of tight junction permeability by medium chain fatty acids in Caco-2 cells. 1998 J. Pharmacol. Exp. Ther. pmid:9435199
Cresteil T et al. Cytochrome P-450 isoenzyme content and monooxygenase activities in rat liver: effect of ontogenesis and pretreatment by phenobarbital and 3-methylcholanthrene. 1986 J. Pharmacol. Exp. Ther. pmid:3941398
Inami Y et al. Topical surfactant-induced pruritus: involvement of histamine released from epidermal keratinocytes. 2013 J. Pharmacol. Exp. Ther. pmid:23220712
Wang JS et al. Transfection and functional expression of CYP4A1 and CYP4A2 using bicistronic vectors in vascular cells and tissues. 2004 J. Pharmacol. Exp. Ther. pmid:15269250
Coyne CB et al. Acute mechanism of medium chain fatty acid-induced enhancement of airway epithelial permeability. 2003 J. Pharmacol. Exp. Ther. pmid:12606647
Imaoka S et al. Identification of CYP2C23 expressed in rat kidney as an arachidonic acid epoxygenase. 1993 J. Pharmacol. Exp. Ther. pmid:8246128
Fang X et al. Activation of peroxisome proliferator-activated receptor alpha by substituted urea-derived soluble epoxide hydrolase inhibitors. 2005 J. Pharmacol. Exp. Ther. pmid:15798002
Xu F et al. Catalytic activity and isoform-specific inhibition of rat cytochrome p450 4F enzymes. 2004 J. Pharmacol. Exp. Ther. pmid:14634044
Bumpus NN and Johnson EF 5-Aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor α-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated protein kinase-independent. 2011 J. Pharmacol. Exp. Ther. pmid:21896918
Mishima M et al. Promotion of nasal absorption of insulin by glycyrrhetinic acid derivatives. I. 1989 J. Pharmacobio-dyn. pmid:2656985
Nakamura J et al. Effect of straight chain fatty acids on seizures induced by picrotoxin and pentylenetetrazole in mice. 1990 J. Pharmacobio-dyn. pmid:2341972
Ogiso T et al. Enhancement by fatty acids of the rectal absorption of propranolol: in vitro evaluation in the rat. 1991 J. Pharmacobio-dyn. pmid:1802986
CARLESS JE and NIXON JR The oxidation of solubilised and emulsified oils. Part III. The oxidation of methyl linoleate in potassium laurate and cetomacrogol dispersions. 1960 J. Pharm. Pharmacol. pmid:13807717
CARLESS JE and NIXON JR The oxidation of solubilised and emulsified oils. Part II. Solubility of benzaldehyde, cyclohexene and methyl linoleate in potassium laurate and cetomacrogol solutions. 1960 J. Pharm. Pharmacol. pmid:13807716
Adachi H et al. Inhibitory effect of prostaglandin E1 on laurate-induced peripheral vascular occlusive sequelae in rabbits: optimized topical formulation with beta-cyclodextrin derivative and penetration enhancer HPE-101. 1992 J. Pharm. Pharmacol. pmid:1361553