lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

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Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Hyperlipidemias D006949 73 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Albuminuria D000419 18 associated lipids
Vasculitis D014657 14 associated lipids
Atherosclerosis D050197 85 associated lipids
Peripheral Arterial Disease D058729 7 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Bird Diseases D001715 4 associated lipids
Obesity, Morbid D009767 8 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Per page 10 20 50 | Total 33

PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

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What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

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Authors Title Published Journal PubMed Link
Iwahashi M et al. Dynamical dimer structure and liquid structure of fatty acids in their binary liquid mixture: dodecanoic and 3-phenylpropionic acids system. 2004 Chem. Phys. Lipids pmid:15081860
Hanley K et al. Development of a plant viral-vector-based gene expression assay for the screening of yeast cytochrome p450 monooxygenases. 2003 Assay Drug Dev Technol pmid:15090141
Hall M et al. Interaction of dexloxiglumide, a cholecystokinin type-1 receptor antagonist, with human cytochromes P450. 2004 Biopharm Drug Dispos pmid:15108219
Hashimoto Y et al. Production of N-lauroylated G protein alpha-subunit in Sf9 insect cells: the type of N-acyl group of Galpha influences G protein-mediated signal transduction. 2004 J. Biochem. pmid:15113830
Katoh K et al. Saturated fatty acids suppress adrenocorticotropic hormone (ACTH) release from rat anterior pituitary cells in vitro. 2004 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:15123208
Choudhury AI et al. Molecular analysis of peroxisome proliferation in the hamster. 2004 Toxicol. Appl. Pharmacol. pmid:15126070
Fichorova RN et al. Interleukin (IL)-1, IL-6, and IL-8 predict mucosal toxicity of vaginal microbicidal contraceptives. 2004 Biol. Reprod. pmid:15128598
Ogawa T et al. Effects of R-102444, an orally active 5-HT2A receptor antagonist, in rat models of peripheral vascular disease. 2004 Vascul. Pharmacol. pmid:15135326
Chu-Kung AF et al. Promotion of peptide antimicrobial activity by fatty acid conjugation. Bioconjug. Chem. pmid:15149180
Göring HD [In memoriam: Niels Ryberg Finsen]. 2004 Hautarzt pmid:15150653
Cardoso DR et al. Comparison between cachaça and rum using pattern recognition methods. 2004 J. Agric. Food Chem. pmid:15161210
Feltrin KL et al. Effects of intraduodenal fatty acids on appetite, antropyloroduodenal motility, and plasma CCK and GLP-1 in humans vary with their chain length. 2004 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:15166004
Himejima M and Kubo I Antimicrobial agents from Licaria puchuri-major and their synergistic effect with polygodial. 1992 J. Nat. Prod. pmid:1517735
Dohme F et al. Digestive and metabolic utilization of lauric, myristic and stearic acid in cows, and associated effects on milk fat quality. 2004 Arch Anim Nutr pmid:15195905
Poloyac SM et al. The effect of isoniazid on CYP2E1- and CYP4A-mediated hydroxylation of arachidonic acid in the rat liver and kidney. 2004 Drug Metab. Dispos. pmid:15205388
Lemaire P et al. Subterminal hydroxylation of lauric acid by microsomes from a marine fish. 1992 Lipids pmid:1522763
Wang JS et al. Transfection and functional expression of CYP4A1 and CYP4A2 using bicistronic vectors in vascular cells and tissues. 2004 J. Pharmacol. Exp. Ther. pmid:15269250
Smit MS et al. Preparation of dodecanol-tolerant strains of Yarrowia lipolytica. 2004 Biotechnol. Lett. pmid:15269560
Jan S et al. Myristic acid increases delta6-desaturase activity in cultured rat hepatocytes. 2004 Mar-Apr Reprod. Nutr. Dev. pmid:15270551
Cho YA and Gwak HS Transdermal delivery of ketorolac tromethamine: effects of vehicles and penetration enhancers. 2004 Drug Dev Ind Pharm pmid:15285328
Svensson A et al. Hydration of an amphiphilic excipient, Gelucire 44/14. 2004 Int J Pharm pmid:15288348
Rothbard JB et al. Role of membrane potential and hydrogen bonding in the mechanism of translocation of guanidinium-rich peptides into cells. 2004 J. Am. Chem. Soc. pmid:15291531
Jeffery B et al. Peroxisome proliferator activated receptor alpha regulates a male-specific cytochrome P450 in mouse liver. 2004 Arch. Biochem. Biophys. pmid:15313227
Smith KW et al. Nature and composition of fat bloom from palm kernel stearin and hydrogenated palm kernel stearin compound chocolates. 2004 J. Agric. Food Chem. pmid:15315397
Lehmler HJ and Bummer PM Mixing of perfluorinated carboxylic acids with dipalmitoylphosphatidylcholine. 2004 Biochim. Biophys. Acta pmid:15328046
Udit AK et al. Cobaltocene-mediated catalytic monooxygenation using holo and heme domain cytochrome P450 BM3. 2004 J. Inorg. Biochem. pmid:15337607
Kitahara T et al. Antimicrobial activity of saturated fatty acids and fatty amines against methicillin-resistant Staphylococcus aureus. 2004 Biol. Pharm. Bull. pmid:15340213
Lorenz C et al. Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cells. 2004 Bioorg. Med. Chem. Lett. pmid:15341962
Miyake M et al. Development of suppository formulation safely improving rectal absorption of rebamipide, a poorly absorbable drug, by utilizing sodium laurate and taurine. 2004 J Control Release pmid:15342181
Artusi M et al. Effect of chemical enhancers and iontophoresis on thiocolchicoside permeation across rabbit and human skin in vitro. 2004 J Pharm Sci pmid:15349953
Kim HW et al. The effect of vehicles and pressure sensitive adhesives on the percutaneous absorption of quercetin through the hairless mouse skin. 2004 Arch. Pharm. Res. pmid:15357005
Kossena GA et al. A novel cubic phase of medium chain lipid origin for the delivery of poorly water soluble drugs. 2004 J Control Release pmid:15380632
Lundgren B et al. Effects of dietary treatment with 11 dicarboxylic acids, diethylcarboxylic esters and fatty acids on peroxisomal fatty acid beta-oxidation, epoxide hydrolases and lauric acid omega-hydroxylation in mouse liver. 1992 Biochem. Pharmacol. pmid:1540233
Lawson RJ et al. Expression and characterization of the two flavodoxin proteins of Bacillus subtilis, YkuN and YkuP: biophysical properties and interactions with cytochrome P450 BioI. 2004 Biochemistry pmid:15449930
Han J et al. Engineered Aeromonas hydrophila for enhanced production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) with alterable monomers composition. 2004 FEMS Microbiol. Lett. pmid:15451119
Hristov AN et al. Effect of sodium laurate on ruminal fermentation and utilization of ruminal ammonia nitrogen for milk protein synthesis in dairy cows. 2004 J. Dairy Sci. pmid:15453498
Dimas DA et al. Ion pair formation as a possible mechanism for the enhancement effect of lauric acid on the transdermal permeation of ondansetron. 2004 Pharm Dev Technol pmid:15458236
Lu XY et al. Molecular cloning of polyhydroxyalkanoate synthesis operon from Aeromonas hydrophila and its expression in Escherichia coli. 2004 Sep-Oct Biotechnol. Prog. pmid:15458314
Afitlhile MM et al. Labeling of major plant lipids and jasmonic acid using [1-(14C)] lauric acid. 2004 Phytochemistry pmid:15464155
Qiu YZ et al. Metabolic engineering for the production of copolyesters consisting of 3-hydroxybutyrate and 3-hydroxyhexanoate by Aeromonas hydrophila. 2004 Macromol Biosci pmid:15468215
Gilman JB et al. Selectivity and stability of organic films at the air-aqueous interface. 2004 J Colloid Interface Sci pmid:15476795
Pandey SK et al. A tribute to Charles David Kelman MD: ophthalmologist, inventor and pioneer of phacoemulsification surgery. 2004 Clin. Experiment. Ophthalmol. pmid:15498067
Kravchenko IA et al. Effect of lauric acid on transdermal penetration of phenazepam in vivo. 2003 Bull. Exp. Biol. Med. pmid:15500077
Tsuge T et al. Mutation effects of a conserved alanine (Ala510) in type I polyhydroxyalkanoate synthase from Ralstonia eutropha on polyester biosynthesis. 2004 Macromol Biosci pmid:15508175
Lord JC and Howard RW A proposed role for the cuticular fatty amides of Liposcelis bostrychophila (Psocoptera: Liposcelidae) in preventing adhesion of entomopathogenic fungi with dry-conidia. 2004 Mycopathologia pmid:15518350
De Lisi R et al. Heat capacity of transfer of (Ethylene oxide)13-(propylene oxide)30-(ethylene oxide)13 from water to the aqueous anionic surfactant solutions at 298 K. A quantitative treatment. 2004 Langmuir pmid:15518478
de Jong AE et al. Behavior of Clostridium perfringens at low temperatures. 2004 Int. J. Food Microbiol. pmid:15527920
Pillai O and Panchagnula R Transdermal iontophoresis of insulin. VI. Influence of pretreatment with fatty acids on permeation across rat skin. Skin Pharmacol Physiol pmid:15528959
Helvig C et al. Drosophila melanogaster CYP6A8, an insect P450 that catalyzes lauric acid (omega-1)-hydroxylation. 2004 Biochem. Biophys. Res. Commun. pmid:15555597
Wojciechowski K and Buffle J The interaction of azacrown ether with fatty acid in nonpolar solvents and at the organic-aqueous interface. 2004 Biosens Bioelectron pmid:15556348
Yamaguchi A et al. Adsorption behavior of lauric acid at heptane/water interface as studied by second harmonic generation spectroscopy and interfacial tensiometry. 2004 Anal Sci pmid:15566143
Elder JP Introduction of Cheryl L. Perry, recipient of the 2004 Research Laureate Medallion. Am J Health Behav pmid:15569590
Renouf-Glauser AC et al. A degradation study of PLLA containing lauric acid. 2005 Biomaterials pmid:15585245
Domínguez de María P et al. Unexpected reaction profile observed in the synthesis of propyl laurate when using Candida rugosa lipases immobilized in microemulsions based organogels. 2004 Biotechnol. Lett. pmid:15604790
Gainer JV et al. Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension. 2005 Circulation pmid:15611369
Yamazaki H et al. Activities of cytochrome p450 enzymes in liver and kidney microsomes from systemic carnitine deficiency mice with a gene mutation of carnitine/organic cation transporter. 2002 Drug Metab. Pharmacokinet. pmid:15618652
Yasui H et al. Evidence for singlet oxygen involvement in rat and human cytochrome P450-dependent substrate oxidations. 2002 Drug Metab. Pharmacokinet. pmid:15618693
Puchkaev AV and Ortiz de Montellano PR The Sulfolobus solfataricus electron donor partners of thermophilic CYP119: an unusual non-NAD(P)H-dependent cytochrome P450 system. 2005 Arch. Biochem. Biophys. pmid:15629120
Fleming I Cytochrome P-450 under pressure: more evidence for a link between 20-hydroxyeicosatetraenoic acid and hypertension. 2005 Circulation pmid:15630035
Matsumoto K et al. Synergistic effects of Glu130Asp substitution in the type II polyhydroxyalkanoate (PHA) synthase: enhancement of PHA production and alteration of polymer molecular weight. Biomacromolecules pmid:15638509
Topakas E et al. Comparison of mesophilic and thermophilic feruloyl esterases: characterization of their substrate specificity for methyl phenylalkanoates. 2005 J. Biotechnol. pmid:15639097
Iwahashi M et al. Dynamical dimer structure and liquid structure of fatty acids in their binary liquid mixture: decanoic/octadecanoic acid and decanoic/dodecanoic acid systems. 2005 Chem. Phys. Lipids pmid:15642581
Takehara K et al. Inhibition of firefly luciferase by alkane analogues. 2005 Biochim. Biophys. Acta pmid:15652187
Lu X et al. Molecular cloning and functional analysis of two polyhydroxyalkanoate synthases from two strains of Aeromonas hydrophila spp. 2005 FEMS Microbiol. Lett. pmid:15668013
Okita RT and Okita JR Characterization of a cytochrome P450 from di(2-ethylhexyl) phthalate-treated rats which hydroxylates fatty acids. 1992 Arch. Biochem. Biophys. pmid:1567203
Nishi Y et al. Ingested medium-chain fatty acids are directly utilized for the acyl modification of ghrelin. 2005 Endocrinology pmid:15677766
Nkondjock A et al. Specific fatty acid intake and the risk of pancreatic cancer in Canada. 2005 Br. J. Cancer pmid:15685231
Ribot F et al. In situ evaluation of interfacial affinity in CeO2 based hybrid nanoparticles by pulsed field gradient NMR. 2005 Chem. Commun. (Camb.) pmid:15719102
Tamaki K et al. Cloning, expression in yeast, and functional characterization of CYP76A4, a novel cytochrome P450 of petunia that catalyzes (omega-1)-hydroxylation of lauric acid. 2005 Biosci. Biotechnol. Biochem. pmid:15725669
Löfgren S et al. Metabolism of human cytochrome P450 marker substrates in mouse: a strain and gender comparison. 2004 Xenobiotica pmid:15742976
Suwanpidokkul N et al. Transdermal delivery of zidovudine (AZT): the effects of vehicles, enhancers, and polymer membranes on permeation across cadaver pig skin. 2004 AAPS PharmSciTech pmid:15760081
Otero C et al. General characterization of noncommercial microbial lipases in hydrolytic and synthetic reactions. 2005 Appl. Biochem. Biotechnol. pmid:15767695
Hayashi S et al. Essential role of singlet oxygen species in cytochrome P450-dependent substrate oxygenation by rat liver microsomes. 2005 Drug Metab. Pharmacokinet. pmid:15770071
Kadohisa M et al. The primate amygdala: Neuronal representations of the viscosity, fat texture, temperature, grittiness and taste of foods. 2005 Neuroscience pmid:15780464
Torres S et al. Alkane-induced expression, substrate binding profile, and immunolocalization of a cytochrome P450 encoded on the nifD excision element of Anabaena 7120. 2005 BMC Microbiol. pmid:15790415
Fang X et al. Activation of peroxisome proliferator-activated receptor alpha by substituted urea-derived soluble epoxide hydrolase inhibitors. 2005 J. Pharmacol. Exp. Ther. pmid:15798002
Kragh-Hansen U et al. Rate-of-dialysis technique: theoretical and practical aspects. 2005 Anal. Biochem. pmid:15802140
Dinan L et al. Synthesis and biological activities of turkesterone 11alpha-acyl derivatives. 2003 J. Insect Sci. pmid:15841223
Weatherill AR et al. Saturated and polyunsaturated fatty acids reciprocally modulate dendritic cell functions mediated through TLR4. 2005 J. Immunol. pmid:15843537
Oba Y et al. Enzymatic and genetic characterization of firefly luciferase and Drosophila CG6178 as a fatty acyl-CoA synthetase. 2005 Biosci. Biotechnol. Biochem. pmid:15849423
Axarli I et al. Engineering the substrate specificity of cytochrome P450 CYP102A2 by directed evolution: production of an efficient enzyme for bioconversion of fine chemicals. 2005 Biomol. Eng. pmid:15857787
Cázares-Delgadillo J et al. Skin permeation enhancement by sucrose esters: a pH-dependent phenomenon. 2005 Int J Pharm pmid:15878811
Minn AL et al. Characterization of microsomal cytochrome P450-dependent monooxygenases in the rat olfactory mucosa. 2005 Drug Metab. Dispos. pmid:15879494
Cho BH et al. Highly polymorphic human CYP4A11 gene. 2005 J. Hum. Genet. pmid:15895287
Jurkiewicz K Adsorptive bubble separation of zinc and cadmium cations in presence of ferric and aluminum hydroxides. 2005 J Colloid Interface Sci pmid:15897071
Hidestrand M et al. Effects of light and dark beer on hepatic cytochrome P-450 expression in male rats receiving alcoholic beverages as part of total enteral nutrition. 2005 Alcohol. Clin. Exp. Res. pmid:15897735
Woelkart K et al. Bioavailability and pharmacokinetics of alkamides from the roots of Echinacea angustifolia in humans. 2005 J Clin Pharmacol pmid:15901750
Wang-Buhler JL et al. CYP2K6 from zebrafish (Danio rerio): cloning, mapping, developmental/tissue expression, and aflatoxin B1 activation by baculovirus expressed enzyme. 2005 Comp. Biochem. Physiol. C Toxicol. Pharmacol. pmid:15907766
Lo KW et al. Effects of fatty acids on growth and poly-3-hydroxybutyrate production in bacteria. 2005 Appl. Biochem. Biotechnol. pmid:15920264
Blanco E et al. A comparative study of the physicochemical properties of perfluorinated and hydrogenated amphiphiles. 2005 J Colloid Interface Sci pmid:15927586
Garfinkel M et al. Insulinotropic potency of lauric acid: a metabolic rationale for medium chain fatty acids (MCF) in TPN formulation. 1992 J. Surg. Res. pmid:1593871
Churchward MA et al. Enhanced detergent extraction for analysis of membrane proteomes by two-dimensional gel electrophoresis. 2005 Proteome Sci pmid:15941475
Kizhakkedathu JN et al. Water-soluble nanoparticles from random copolymer and oppositely charged surfactant, 3a. Nanoparticles of poly(ethylene glycol)-based cationic random copolymer and fatty acid salts. 2005 Macromol Biosci pmid:15948231
Skrivanová E et al. Susceptibility of Clostridium perfringens to C-C fatty acids. 2005 Lett. Appl. Microbiol. pmid:15960756
Little TJ et al. Dose-related effects of lauric acid on antropyloroduodenal motility, gastrointestinal hormone release, appetite, and energy intake in healthy men. 2005 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:15961531
Ouyang SP et al. [Fermentative production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) by recombinant Aeromonas hydrophila 4AK4 (pTG01)]. 2003 Sheng Wu Gong Cheng Xue Bao pmid:15971584
Ozalp C et al. Bimolecular fluorescence complementation analysis of cytochrome p450 2c2, 2e1, and NADPH-cytochrome p450 reductase molecular interactions in living cells. 2005 Drug Metab. Dispos. pmid:15980100
Berry D Pierre-François Olive Rayer: biography. 2005 Med Hist Suppl pmid:15981855
Jiang H et al. Anion-mediated phase transfer of Zinc(II)-coordinated tyrosine derivatives. 2005 Org. Lett. pmid:15987193
Rayan P et al. The effects of saturated fatty acids on Giardia duodenalis trophozoites in vitro. 2005 Parasitol. Res. pmid:15991042