lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

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Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Colonic Neoplasms D003110 161 associated lipids
Lung Neoplasms D008175 171 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 50 | Total 33

PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

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Per page 10 20 50 100 | Total 1837
Authors Title Published Journal PubMed Link
Alves NF et al. Acute Treatment with Lauric Acid Reduces Blood Pressure and Oxidative Stress in Spontaneously Hypertensive Rats. 2017 Basic Clin. Pharmacol. Toxicol. pmid:28054477
Stark K et al. Expression of CYP4F12 in gastrointestinal and urogenital epithelia. 2004 Basic Clin. Pharmacol. Toxicol. pmid:15078342
Russell VA et al. Animal models of attention-deficit hyperactivity disorder. 2005 Behav Brain Funct pmid:16022733
Hu H et al. A novel class of antagonists for the FFAs receptor GPR40. 2009 Biochem. Biophys. Res. Commun. pmid:19818732
Imaoka S et al. Induction of renal cytochrome P-450 in hepatic microsomes of diabetic rats. 1988 Biochem. Biophys. Res. Commun. pmid:3365247
Alterman MA et al. Heteroatom substitution shifts regioselectivity of lauric acid metabolism from omega-hydroxylation to (omega-1)-oxidation. 1995 Biochem. Biophys. Res. Commun. pmid:7575514
Kiffel L et al. Purification and characterization of a cytochrome P-450 isozyme isolated from the liver of rats pretreated with clofibrate. 1988 Biochem. Biophys. Res. Commun. pmid:3140811
Björkhem I and Hamberg M On the rate-limiting step in W-hydroxylation of lauric acid. 1972 Biochem. Biophys. Res. Commun. pmid:4662395
Amet Y et al. Evidence that cytochrome P450 2E1 is involved in the (omega-1)-hydroxylation of lauric acid in rat liver microsomes. 1994 Biochem. Biophys. Res. Commun. pmid:8093035
Tanaka T et al. Saturated and trans-unsaturated fatty acids elicit high levels of superoxide generation in intact and cell-free preparations of neutrophils. 1987 Biochem. Biophys. Res. Commun. pmid:3034258