| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
lauric acid
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
Cross Reference
Introduction
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with lauric acid?
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Am. J. Clin. Nutr. (1)
- Am. J. Physiol. Heart Circ. Physiol. (1)
- Antimicrob. Agents Chemother. (1)
- Others (7)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with lauric acid
PubChem Associated disorders and diseases
What pathways are associated with lauric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with lauric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with lauric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with lauric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with lauric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with lauric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with lauric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bains SK et al. | Immunochemical study on the contribution of hypolipidaemic-induced cytochrome P-452 to the metabolism of lauric acid and arachidonic acid. | 1985 | Biochem. Pharmacol. | pmid:3929789 |
| Fournel S et al. | Structure-dependent induction of bilirubin glucuronidation and lauric acid 12-hydroxylation by arylcarboxylic acids chemically related to clofibrate. | 1985 | Biochim. Biophys. Acta | pmid:3931693 |
| Capdevila J et al. | Influence of a fibric acid type of hypolipidemic agent on the oxidative metabolism of arachidonic acid by liver microsomal cytochrome P-450. | 1985 | Arch. Biochem. Biophys. | pmid:3933431 |
| Cresteil T et al. | Cytochrome P-450 isoenzyme content and monooxygenase activities in rat liver: effect of ontogenesis and pretreatment by phenobarbital and 3-methylcholanthrene. | 1986 | J. Pharmacol. Exp. Ther. | pmid:3941398 |
| Pedersen AO et al. | Laurate binding to human serum albumin. Multiple binding equilibria investigated by a dialysis exchange method. | 1986 | Eur. J. Biochem. | pmid:3948866 |
| Thomson AB | Resection of rabbit ileum: effect on jejunal structure and carrier-mediated and passive uptake. | 1986 | Q J Exp Physiol | pmid:3952260 |
| Qureshi N et al. | Monophosphoryl lipid A obtained from lipopolysaccharides of Salmonella minnesota R595. Purification of the dimethyl derivative by high performance liquid chromatography and complete structural determination. | 1985 | J. Biol. Chem. | pmid:3988753 |
| Spencer GK and Waldroup PW | The influence of amprolium and butynorate on growth rate and feed utilization by large white turkeys. | 1985 | Poult. Sci. | pmid:4001047 |
| Kaku M et al. | Multiple forms of cytochrome P-450 in rabbit colon microsomes. | 1985 | J. Biochem. | pmid:4008473 |
| Shoun H et al. | Subterminal hydroxylation of fatty acids by a cytochrome P-450-dependent enzyme system from a fungus, Fusarium oxysporum. | 1985 | J. Biochem. | pmid:4019433 |
| Rafflenbeul D and Zbinden G | Circulating platelet aggregates and thrombocytopenia induced by intravenous infusions of arachidonic and lauric acids in guinea pigs. | 1977 | Acta Haematol. | pmid:402770 |
| Halpert J et al. | Isozyme selectivity of the inhibition of rat liver cytochromes P-450 by chloramphenicol in vivo. | 1985 | Mol. Pharmacol. | pmid:4033629 |
| Norman HA and Thompson GA | Effects of low-temperature stress on the metabolism of phosphatidylglycerol molecular species in Dunaliella salina. | 1985 | Arch. Biochem. Biophys. | pmid:4051499 |
| Pita ML et al. | Influence of the mother's weight and socioeconomic status on the fatty acid composition of human milk. | 1985 | Ann. Nutr. Metab. | pmid:4062247 |
| Gibson GG and Bains SK | Cytochrome P-450 isoenzymes involved in fatty acid metabolism. | 1985 | Biochem. Soc. Trans. | pmid:4065418 |
| Kitajima Y and Thompson GA | Self-regulation of membrane fluidity. The effect of saturated normal and methoxy fatty acid supplementation on Tetrahymena membrane physical properties and lipid composition. | 1977 | Biochim. Biophys. Acta | pmid:406916 |
| Kawamura K et al. | Effect of cilostazol, a new antithrombotic drug, on an experimental model of peripheral circulation insufficiency. | 1985 | Arzneimittelforschung | pmid:4074428 |
| Hotke C et al. | Jejunal uptake of sugars, cholesterol, fatty acids, and fatty alcohols in vivo in diabetic rats. | 1985 | Can. J. Physiol. Pharmacol. | pmid:4075254 |
| Weber N | Metabolism of orally administered rac-1-O-[1'-14C]dodecylglycerol and nutritional effects of dietary rac-1-O-dodecylglycerol in mice. | 1985 | J. Lipid Res. | pmid:4086944 |
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| Chanussot F and Debry G | [Comparison in genetically obese and normal rats in the secretion of lipids synthesized from labeled lauric and oleic acids and glycerol in isolated perfused liver]. | 1977 | C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. | pmid:410533 |
| Chanussot F and Debry G | [Comparison in genetically obese and normal rats of the uptake and incorporation of labelled lauric acid, oleic acid, and glycerol by the isolated perfused liver]. | 1977 | C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. | pmid:411584 |
| Migliore-Samour D et al. | Adjuvant activities of chemically modified water-soluble substances from Mycobacterium tuberculosis. | 1977 | Immunology | pmid:411741 |
| Sasame HA et al. | The possible involvement of cytochrome b5 in the oxidation of lauric acid by microsomes from kidney cortex and liver of rats. | 1974 | Life Sci. | pmid:4129689 |
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| Boersma ER | Changes in fatty-acid composition of body fat before and after birth in Tanzania: an international comparative study. | 1979 | Br Med J | pmid:435841 |
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| Kabara JJ et al. | Fatty acids and derivatives as antimicrobial agents. | 1972 | Antimicrob. Agents Chemother. | pmid:4670656 |
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| Spector AA et al. | Quantitative analysis of uptake of free fatty acid by mammalian cells: lauric acid and human erythrocytes. | 1972 | J. Lipid Res. | pmid:5041270 |
| Starha L and Chalabala M | [Oral long-acting drugs. 8. Effects of palmitic and lauric acid and their glycerine esters on the slowing of the drug release]. | 1972 | Cesk Farm | pmid:5075740 |
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| Okita RT et al. | Lauric acid hydroxylation in human liver and kidney cortex microsomes. | 1979 | Biochem. Pharmacol. | pmid:533546 |
| Srivastava KC | Effect of some saturated and unsaturated fatty acids on in vitro platelet utilization of arachidonic acid. | 1979 | Prostaglandins Med | pmid:550161 |
| Kato A and Arima K | Inhibitory effect of sucrose ester of lauric acid on the growth of Escherichia coli. | 1971 | Biochem. Biophys. Res. Commun. | pmid:5543940 |
| Jenkins CL et al. | Fatty acid composition of Simonsiella strains. | 1977 | Arch. Microbiol. | pmid:560178 |
| Fan LL et al. | Microsomal lauric acid 11- and 12-hydroxylation: a new assay method utilizing high pressure liquid chromatography. | 1976 | Anal. Biochem. | pmid:5910 |
| Okita RT and Masters BS | Effect of phenobarbital treatment and cytochrome P-450 inhibitors on the laurate omega- and (omega - 1)-hydroxylase activities of rat liver microsomes. | 1980 May-Jun | Drug Metab. Dispos. | pmid:6104577 |
| Demarne Y et al. | Effects of maternal dodecanoic or lauric acid (C12:0) feeding on milk fatty acid secretion and lipogenesis in the suckling rat. | 1977 | Biol. Neonate | pmid:610766 |
| Dell HD et al. | Etofenamate fatty acid asters. An example of a new route of drug metabolism. | 1982 Jan-Feb | Drug Metab. Dispos. | pmid:6124384 |
| Orton TC and Parker GL | The effect of hypolipidemic agents on the hepatic microsomal drug-metabolizing enzyme system of the rat. Induction of cytochrome(s) P-450 with specificity toward terminal hydroxylation of lauric acid. | 1982 Mar-Apr | Drug Metab. Dispos. | pmid:6124394 |
| Albro PW et al. | In vitro metabolism of mono-2-ethylhexyl phthalate by microsomal enzymes. Similarity to omega- and (omega-1) oxidation of fatty acids. | 1984 Nov-Dec | Drug Metab. Dispos. | pmid:6150824 |