MeSH term | MeSH ID | Detail |
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Colonic Neoplasms | D003110 | 161 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with lauric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Brodersen R et al. | Cobinding of bilirubin and sulfonamide and of two bilirubin molecules to human serum albumin: a site model. | 1987 | Arch. Biochem. Biophys. | pmid:3813550 |
Hoch U et al. | Structural determination of the substrate specificities and regioselectivities of the rat and human fatty acid omega-hydroxylases. | 2000 | Arch. Biochem. Biophys. | pmid:10620324 |
Williams DE et al. | Regiospecific hydroxylation of lauric acid at the (omega-1) position by hepatic and kidney microsomal cytochromes P-450 from rainbow trout. | 1984 | Arch. Biochem. Biophys. | pmid:6732245 |
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Kawashima H et al. | Human fatty acid omega-hydroxylase, CYP4A11: determination of complete genomic sequence and characterization of purified recombinant protein. | 2000 | Arch. Biochem. Biophys. | pmid:10860550 |
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Wang MH et al. | Cloning, sequencing, and cDNA-directed expression of the rat renal CYP4A2: arachidonic acid omega-hydroxylation and 11,12-epoxidation by CYP4A2 protein. | 1996 | Arch. Biochem. Biophys. | pmid:8954571 |
Powell PK et al. | Identification of CYP4A11 as the major lauric acid omega-hydroxylase in human liver microsomes. | 1996 | Arch. Biochem. Biophys. | pmid:8914854 |
Okita RT and Okita JR | Characterization of a cytochrome P450 from di(2-ethylhexyl) phthalate-treated rats which hydroxylates fatty acids. | 1992 | Arch. Biochem. Biophys. | pmid:1567203 |
Jeffery B et al. | Peroxisome proliferator activated receptor alpha regulates a male-specific cytochrome P450 in mouse liver. | 2004 | Arch. Biochem. Biophys. | pmid:15313227 |
Chaurasia CS et al. | Biochemical characterization of lauric acid omega-hydroxylation by a CYP4A1/NADPH-cytochrome P450 reductase fusion protein. | 1995 | Arch. Biochem. Biophys. | pmid:7872779 |
Sato H et al. | Multiple binding of bilirubin to human serum albumin and cobinding with laurate. | 1988 | Arch. Biochem. Biophys. | pmid:2829743 |
Chavez JA and Summers SA | Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes. | 2003 | Arch. Biochem. Biophys. | pmid:14592453 |
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Que Hee SS and Zainal H | Permeation of herbicidal dichlobenil from a Casoron formulation through nitrile gloves. | 2010 | Arch. Environ. Contam. Toxicol. | pmid:19855916 |
Green PR and Geer BW | Changes in the fatty acid composition of Drosophila melanogaster during development and ageing. | 1979 | Arch. Int. Physiol. Biochim. | pmid:93438 |
Demarne Y et al. | Comparison of long term lipogenic effects of two different medium-chain triglycerides (tri C8: O and tri C12 : O) in the growing rat. | 1978 | Arch. Int. Physiol. Biochim. | pmid:80196 |
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Laurila H et al. | The cytochrome P450-containing monooxygenase of Trichosporon cutaneum: occurrence and properties. | 1984 | Arch. Microbiol. | pmid:6397156 |