MeSH term | MeSH ID | Detail |
---|---|---|
Bird Diseases | D001715 | 4 associated lipids |
Nephrosis, Lipoid | D009402 | 2 associated lipids |
Vascular System Injuries | D057772 | 2 associated lipids |
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with lauric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Tenma T et al. | Development of new lipophilic derivatives of tetragastrin: physicochemical characteristics and intestinal absorption of acyl-tetragastrin derivatives in rats. | 1993 | Pharm. Res. | pmid:8272412 |
Smith SW and Anderson BD | Salt and mesophase formation in aqueous suspensions of lauric acid. | 1993 | Pharm. Res. | pmid:8272419 |
Yasuda H et al. | An animal model of chronic ischemic neuropathy with proliferative changes of nerve microvessel wall. | 1993 | J. Neurol. Sci. | pmid:8289080 |
Pinot F et al. | New cytochrome P450-dependent reactions from wheat: terminal and sub-terminal hydroxylation of oleic acid by microsomes from naphthalic acid anhydride and phenobarbital induced wheat seedlings. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8297392 |
Tholstrup T et al. | Fat high in stearic acid favorably affects blood lipids and factor VII coagulant activity in comparison with fats high in palmitic acid or high in myristic and lauric acids. | 1994 | Am. J. Clin. Nutr. | pmid:8310987 |
Goldberg ML and Enig MG | Palmitic and lauric acids and serum cholesterol. | 1993 | Am. J. Clin. Nutr. | pmid:8338054 |
Orlowski M et al. | Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids. | 1993 | Biochemistry | pmid:8431436 |
Mustad VA et al. | Comparison of the effects of diets rich in stearic acid versus myristic acid and lauric acid on platelet fatty acids and excretion of thromboxane A2 and PGI2 metabolites in healthy young men. | 1993 | Metab. Clin. Exp. | pmid:8487669 |
Sawamura A et al. | Catalytic properties of rabbit kidney fatty acid omega-hydroxylase cytochrome P-450ka2 (CYP4A7). | 1993 | Biochim. Biophys. Acta | pmid:8504139 |
Niederprüm HJ et al. | Inhibition of steroid 5 alpha-reductase activity by aliphatic fatty acids. Candidates for chemoprevention of prostate cancer. | 1995 | Ann. N. Y. Acad. Sci. | pmid:8526353 |
Valdes E et al. | Dietary fish oil and cytochrome P-450 monooxygenase activity in rat liver and kidney. | 1995 | Lipids | pmid:8538384 |
Lapshina EA et al. | Effect of free fatty acids on the structure and properties of erythrocyte membrane. | 1995 | Scand. J. Clin. Lab. Invest. | pmid:8545597 |
Mabrey S and Sturtevant JM | Incorporation of saturated fatty acids into phosphatidylcholine bilayers. | 1977 | Biochim. Biophys. Acta | pmid:856286 |
Bambal RB and Hanzlik RP | Active site structure and substrate specificity of cytochrome P450 4A1: steric control of ligand approach perpendicular to heme plane. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8605007 |
Pronczuk A et al. | Plasma lipids are affected similarly by dietary lauric or palmitic acid in gerbils and monkeys. | 1995 | Lipids | pmid:8614307 |
Amet Y et al. | Validation of the (omega-1)-hydroxylation of lauric acid as an in vitro substrate probe for human liver CYP2E1. | 1995 | Biochem. Pharmacol. | pmid:8615855 |
Temme EH et al. | Comparison of the effects of diets enriched in lauric, palmitic, or oleic acids on serum lipids and lipoproteins in healthy women and men. | 1996 | Am. J. Clin. Nutr. | pmid:8644684 |
Shet Ms et al. | The omega-hydroxlyation of lauric acid: oxidation of 12-hydroxlauric acid to dodecanedioic acid by a purified recombinant fusion protein containing P450 4A1 and NADPH-P450 reductase. | 1996 | Arch. Biochem. Biophys. | pmid:8651697 |
Narayanan VS and Storch J | Fatty acid transfer in taurodeoxycholate mixed micelles. | 1996 | Biochemistry | pmid:8652524 |
Castle PJ et al. | Human liver lauric acid hydroxylase activities. | 1995 | Drug Metab. Dispos. | pmid:8654190 |