lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

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Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Bird Diseases D001715 4 associated lipids
Albuminuria D000419 18 associated lipids
Acne Vulgaris D000152 35 associated lipids
Per page 10 20 50 | Total 33

PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

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What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

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Authors Title Published Journal PubMed Link
Hu H et al. A novel class of antagonists for the FFAs receptor GPR40. 2009 Biochem. Biophys. Res. Commun. pmid:19818732
Imaoka S et al. Induction of renal cytochrome P-450 in hepatic microsomes of diabetic rats. 1988 Biochem. Biophys. Res. Commun. pmid:3365247
Roomi MW et al. Decreased expression of cytochrome P-452 in the resistance phenotype characteristic of putative preneoplastic hepatocyte nodules during hepatocarcinogenesis. 1988 Biochem. Biophys. Res. Commun. pmid:3365259
Liu K et al. Isolation and biochemical characterization of two lipases from a metagenomic library of China Holstein cow rumen. 2009 Biochem. Biophys. Res. Commun. pmid:19486892
Alterman MA et al. Heteroatom substitution shifts regioselectivity of lauric acid metabolism from omega-hydroxylation to (omega-1)-oxidation. 1995 Biochem. Biophys. Res. Commun. pmid:7575514
Kiffel L et al. Purification and characterization of a cytochrome P-450 isozyme isolated from the liver of rats pretreated with clofibrate. 1988 Biochem. Biophys. Res. Commun. pmid:3140811
Björkhem I On the mechanism of 11-hydroxylation of lauric acid by rat liver microsomes. 1973 Biochem. Biophys. Res. Commun. pmid:4689066
Björkhem I and Hamberg M On the rate-limiting step in W-hydroxylation of lauric acid. 1972 Biochem. Biophys. Res. Commun. pmid:4662395
Kato A and Arima K Inhibitory effect of sucrose ester of lauric acid on the growth of Escherichia coli. 1971 Biochem. Biophys. Res. Commun. pmid:5543940
Miranda CL et al. Regiospecificity in the hydroxylation of lauric acid by rainbow trout hepatic cytochrome P450 isozymes. 1990 Biochem. Biophys. Res. Commun. pmid:2403346
Amet Y et al. Evidence that cytochrome P450 2E1 is involved in the (omega-1)-hydroxylation of lauric acid in rat liver microsomes. 1994 Biochem. Biophys. Res. Commun. pmid:8093035
Imaoka S et al. A transgenic mouse expressing human CYP4B1 in the liver. 2001 Biochem. Biophys. Res. Commun. pmid:11396967
Helvig C et al. Drosophila melanogaster CYP6A8, an insect P450 that catalyzes lauric acid (omega-1)-hydroxylation. 2004 Biochem. Biophys. Res. Commun. pmid:15555597
Tanaka T et al. Saturated and trans-unsaturated fatty acids elicit high levels of superoxide generation in intact and cell-free preparations of neutrophils. 1987 Biochem. Biophys. Res. Commun. pmid:3034258
Pinot F et al. New cytochrome P450-dependent reactions from wheat: terminal and sub-terminal hydroxylation of oleic acid by microsomes from naphthalic acid anhydride and phenobarbital induced wheat seedlings. 1994 Biochem. Biophys. Res. Commun. pmid:8297392
Yoshimoto M et al. Purification and characterization of two forms of cytochrome P-450 from rat kidney cortex microsomes. 1986 Biochem. Int. pmid:3814156
Takahashi K et al. Ester synthesis at extraordinarily low temperature of -3 degrees C by modified lipase in benzene. 1985 Biochem. Int. pmid:3927919
Tambo F et al. Auto-oxidation of Lingula unguis and Siphonosoma cumanense hemerythrins induced by some perturbants. 1989 Biochem. Int. pmid:2764951
Imaoka S et al. Omega- and (omega-1)-hydroxylation of lauric acid and arachidonic acid by rat renal cytochrome P-450. 1989 Biochem. Int. pmid:2504167
Lundell K Cloning and expression of two novel pig liver and kidney fatty acid hydroxylases [cytochrome P450 (CYP)4A24 and CYP4A25]. 2002 Biochem. J. pmid:11931657