MeSH term | MeSH ID | Detail |
---|---|---|
Bird Diseases | D001715 | 4 associated lipids |
Albuminuria | D000419 | 18 associated lipids |
Acne Vulgaris | D000152 | 35 associated lipids |
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with lauric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hu H et al. | A novel class of antagonists for the FFAs receptor GPR40. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19818732 |
Imaoka S et al. | Induction of renal cytochrome P-450 in hepatic microsomes of diabetic rats. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3365247 |
Roomi MW et al. | Decreased expression of cytochrome P-452 in the resistance phenotype characteristic of putative preneoplastic hepatocyte nodules during hepatocarcinogenesis. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3365259 |
Liu K et al. | Isolation and biochemical characterization of two lipases from a metagenomic library of China Holstein cow rumen. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19486892 |
Alterman MA et al. | Heteroatom substitution shifts regioselectivity of lauric acid metabolism from omega-hydroxylation to (omega-1)-oxidation. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7575514 |
Kiffel L et al. | Purification and characterization of a cytochrome P-450 isozyme isolated from the liver of rats pretreated with clofibrate. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3140811 |
Björkhem I | On the mechanism of 11-hydroxylation of lauric acid by rat liver microsomes. | 1973 | Biochem. Biophys. Res. Commun. | pmid:4689066 |
Björkhem I and Hamberg M | On the rate-limiting step in W-hydroxylation of lauric acid. | 1972 | Biochem. Biophys. Res. Commun. | pmid:4662395 |
Kato A and Arima K | Inhibitory effect of sucrose ester of lauric acid on the growth of Escherichia coli. | 1971 | Biochem. Biophys. Res. Commun. | pmid:5543940 |
Miranda CL et al. | Regiospecificity in the hydroxylation of lauric acid by rainbow trout hepatic cytochrome P450 isozymes. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2403346 |
Amet Y et al. | Evidence that cytochrome P450 2E1 is involved in the (omega-1)-hydroxylation of lauric acid in rat liver microsomes. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8093035 |
Imaoka S et al. | A transgenic mouse expressing human CYP4B1 in the liver. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11396967 |
Helvig C et al. | Drosophila melanogaster CYP6A8, an insect P450 that catalyzes lauric acid (omega-1)-hydroxylation. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15555597 |
Tanaka T et al. | Saturated and trans-unsaturated fatty acids elicit high levels of superoxide generation in intact and cell-free preparations of neutrophils. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3034258 |
Pinot F et al. | New cytochrome P450-dependent reactions from wheat: terminal and sub-terminal hydroxylation of oleic acid by microsomes from naphthalic acid anhydride and phenobarbital induced wheat seedlings. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8297392 |
Yoshimoto M et al. | Purification and characterization of two forms of cytochrome P-450 from rat kidney cortex microsomes. | 1986 | Biochem. Int. | pmid:3814156 |
Takahashi K et al. | Ester synthesis at extraordinarily low temperature of -3 degrees C by modified lipase in benzene. | 1985 | Biochem. Int. | pmid:3927919 |
Tambo F et al. | Auto-oxidation of Lingula unguis and Siphonosoma cumanense hemerythrins induced by some perturbants. | 1989 | Biochem. Int. | pmid:2764951 |
Imaoka S et al. | Omega- and (omega-1)-hydroxylation of lauric acid and arachidonic acid by rat renal cytochrome P-450. | 1989 | Biochem. Int. | pmid:2504167 |
Lundell K | Cloning and expression of two novel pig liver and kidney fatty acid hydroxylases [cytochrome P450 (CYP)4A24 and CYP4A25]. | 2002 | Biochem. J. | pmid:11931657 |