MeSH term | MeSH ID | Detail |
---|---|---|
Bird Diseases | D001715 | 4 associated lipids |
Albuminuria | D000419 | 18 associated lipids |
Acne Vulgaris | D000152 | 35 associated lipids |
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with lauric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Honoré B et al. | Cobinding of bilirubin and laurate to human serum albumin: spectroscopic characterization of stoichiometric complexes. | 1988 | Arch. Biochem. Biophys. | pmid:3178221 |
Csordas A and Rybczynska M | Critical temperatures for the interaction of free fatty acids with the erythrocyte membrane. | 1988 | Biochim. Biophys. Acta | pmid:3179287 |
Andreiuk GM and Kiselev PA | [Initiation of lipid peroxidation as a result of hemoglobin transformation into hemichrome induced by free fatty acids]. | 1988 | Biokhimiia | pmid:3179347 |
Magdalou J et al. | Effect of 1-benzylimidazole on cytochromes P-450 induction and on the activities of epoxide hydrolases and UDP-glucuronosyltransferases in rat liver. | 1988 | Biochem. Pharmacol. | pmid:2840913 |
Imaoka S et al. | Induction of renal cytochrome P-450 in hepatic microsomes of diabetic rats. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3365247 |
Roomi MW et al. | Decreased expression of cytochrome P-452 in the resistance phenotype characteristic of putative preneoplastic hepatocyte nodules during hepatocarcinogenesis. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3365259 |
Bacher MA and Gibson GG | Chlorophenoxyacid herbicides induce microsomal cytochrome P-450 IVA1 (P-452) in rat liver. | 1988 | Chem. Biol. Interact. | pmid:3365825 |
De Cuyper M and Joniau M | Magnetoliposomes. Formation and structural characterization. | 1988 | Eur. Biophys. J. | pmid:3366097 |
Romano MC et al. | Determination of microsomal lauric acid hydroxylase activity by HPLC with flow-through radiochemical quantitation. | 1988 | Anal. Biochem. | pmid:3389520 |
Pedersen AO and Brodersen R | Myristic acid binding to human serum albumin investigated by dialytic exchange rate. | 1988 | J. Biol. Chem. | pmid:3392011 |
Pazo JA and Parafita MA | Synergism of ethanol and clofibrate in the lauric acid hydroxylation. | 1988 | Drug Alcohol Depend | pmid:3416732 |
Whiting P and Dinan L | Formation of apolar ecdysteroid conjugates by ovaries of the house cricket Acheta domesticus in vitro. | 1988 | Biochem. J. | pmid:3421912 |
Salaün JP et al. | Differential inactivation of plant lauric acid omega- and in-chain-hydroxylases by terminally unsaturated fatty acids. | 1988 | Arch. Biochem. Biophys. | pmid:3341756 |
Homan R and Pownall HJ | Transbilayer diffusion of phospholipids: dependence on headgroup structure and acyl chain length. | 1988 | Biochim. Biophys. Acta | pmid:3342229 |
Sharma R et al. | Co-induction of microsomal cytochrome P-452 and the peroxisomal fatty acid beta-oxidation pathway in the rat by clofibrate and di-(2-ethylhexyl)phthalate. Dose-response studies. | 1988 | Biochem. Pharmacol. | pmid:3355594 |
Lorenzana RM et al. | Localization of cytochrome P-450 in the head and trunk kidney of rainbow trout (Salmo gairdneri). | 1988 | Toxicol. Appl. Pharmacol. | pmid:3188021 |
Goldberg M et al. | Enzymatic ester synthesis with continuous measurement of water activity. | 1988 | Biochim. Biophys. Acta | pmid:3196717 |
CaJacob CA et al. | The catalytic site of rat hepatic lauric acid omega-hydroxylase. Protein versus prosthetic heme alkylation in the omega-hydroxylation of acetylenic fatty acids. | 1988 | J. Biol. Chem. | pmid:3198593 |
Kiffel L et al. | Purification and characterization of a cytochrome P-450 isozyme isolated from the liver of rats pretreated with clofibrate. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3140811 |
Zoeller RA et al. | A possible role for plasmalogens in protecting animal cells against photosensitized killing. | 1988 | J. Biol. Chem. | pmid:3403547 |
Sumimoto J et al. | Characterization of human neutrophil leukotriene B4 omega-hydroxylase as a system involving a unique cytochrome P-450 and NADPH-cytochrome P-450 reductase. | 1988 | Eur. J. Biochem. | pmid:3127205 |
Eriksson LO and Boström H | Deactivation of sulindac-sulphide by human renal microsomes. | 1988 | Pharmacol. Toxicol. | pmid:3133648 |
Imai Y and Nakamura M | The importance of threonine-301 from cytochromes P-450 (laurate (omega-1)-hydroxylase and testosterone 16 alpha-hydroxylase) in substrate binding as demonstrated by site-directed mutagenesis. | 1988 | FEBS Lett. | pmid:3134259 |
Qureshi N et al. | Complete structural determination of lipopolysaccharide obtained from deep rough mutant of Escherichia coli. Purification by high performance liquid chromatography and direct analysis by plasma desorption mass spectrometry. | 1988 | J. Biol. Chem. | pmid:3136169 |
Gergely J | [S. Tonegawa, 1987 Nobel Prize laureate in medicine]. | 1988 | Orv Hetil | pmid:3050756 |
Lehmann V and Benninghoff B | Isolation of a mutant from Salmonella typhimurium producing acyl-deficient lipopolysaccharides. | 1988 | Eur. J. Biochem. | pmid:3061817 |
Dmitriev VV et al. | [Yeasts utilizing the surface-active substance Laurox-9]. | 1988 Mar-Apr | Mikrobiologiia | pmid:3419368 |
Levine WG and Raza H | Mechanism of azoreduction of dimethylaminoazobenzene by rat liver NADPH-cytochrome P-450 reductase and partially purified cytochrome P-450. Oxygen and carbon monoxide sensitivity and stimulation by FAD and FMN. | 1988 May-Jun | Drug Metab. Dispos. | pmid:2900738 |
Christensen E et al. | Beta-oxidation of medium chain (C8-C14) fatty acids studied in isolated liver cells. | 1989 | Biochim. Biophys. Acta | pmid:2752017 |
Wada M et al. | Mechanism of biosynthesis of unsaturated fatty acids in Pseudomonas sp. strain E-3, a psychrotrophic bacterium. | 1989 | J. Bacteriol. | pmid:2753856 |
Ryals PE et al. | Lipid modification during cytodifferentiation of Tetrahymena vorax. Whole cell phospholipids and triacylglycerols of microstomal and macrostomal phenotypes. | 1989 | Biochim. Biophys. Acta | pmid:2730920 |
Sharma RK et al. | Role of hepatic and renal cytochrome P-450 IVA1 in the metabolism of lipid substrates. | 1989 | Biochem. Pharmacol. | pmid:2554928 |
Makowska JM et al. | Species differences in the hepatic response to a potent peroxisome proliferator. | 1989 | Biochem. Soc. Trans. | pmid:2628085 |
Laignelet L et al. | Induction and inhibition of rat liver cytochrome(s) P-450 by an imidazole fungicide (prochloraz). | 1989 | Toxicology | pmid:2631296 |
Jarabak R and Westley J | The sulfur-cyanolysis sites of serum albumin: metabolite competition studies. | 1989 | J. Biochem. Toxicol. | pmid:2634097 |
Leon W et al. | Fatty acid composition of amastigote and trypomastigote forms of Trypanosoma cruzi. | 1989 | Acta Trop. | pmid:2565074 |
Woolfrey SG et al. | The effect of Miglycol 812 oil on the oral absorption of propranolol in the rat. | 1989 | J. Pharm. Pharmacol. | pmid:2571709 |
Miranda CL et al. | Purification and characterization of hepatic steroid hydroxylases from untreated rainbow trout. | 1989 | Arch. Biochem. Biophys. | pmid:2536262 |
Imai Y et al. | Structure-function relationships of cytochrome P-450 laurate (omega-1)-hydroxylase. | 1989 | Drug Metab. Rev. | pmid:2680391 |
Graham SA | Cuphea: a new plant source of medium-chain fatty acids. | 1989 | Crit Rev Food Sci Nutr | pmid:2653730 |
Mishima M et al. | Promotion of nasal absorption of insulin by glycyrrhetinic acid derivatives. I. | 1989 | J. Pharmacobio-dyn. | pmid:2656985 |
Morisaki H | [Inhibition of neutrophil function by solvent of injectable sedatives--effects of propylene glycol, ethanol and benzyl alcohol]. | 1989 | Masui | pmid:2614886 |
Kocarek TA and Feller DR | Quantitative assessment of enzyme induction by peroxisome proliferators and application to determination of effects on triglyceride biosynthesis in primary cultures of rat hepatocytes. | 1989 | Biochem. Pharmacol. | pmid:2597188 |
Fibach E et al. | Analysis of cellular heterogeneity in the response of human leukemic cells to photosensitization induced by pyrene-containing fatty acid. | 1989 | Leuk. Res. | pmid:2559259 |
Yokotani N et al. | Two forms of omega-hydroxylase toward prostaglandin A and laurate. cDNA cloning and their expression. | 1989 | J. Biol. Chem. | pmid:2600085 |
Khodari M et al. | Applications in drug analysis of carbon paste electrodes modified by fatty acids. | 1989 | J Pharm Biomed Anal | pmid:2490534 |
Imai Y and Nakamura M | Point mutations at threonine-301 modify substrate specificity of rabbit liver microsomal cytochromes P-450 (laurate (omega-1)-hydroxylase and testosterone 16 alpha-hydroxylase). | 1989 | Biochem. Biophys. Res. Commun. | pmid:2493247 |
Borlakoglu JT et al. | Evidence for the induction of cytochrome P-452 in rat liver by Aroclor 1254, a commercial mixture of polychlorinated biphenyls. | 1989 | FEBS Lett. | pmid:2497034 |
Aarsaether N et al. | Changes in peroxisomes and mitochondria in liver of ethionine exposed rats: a biochemical and morphological investigation. | 1989 | Carcinogenesis | pmid:2498002 |
Lake BG et al. | Comparative studies on nafenopin-induced hepatic peroxisome proliferation in the rat, Syrian hamster, guinea pig, and marmoset. | 1989 | Toxicol. Appl. Pharmacol. | pmid:2499080 |
Benveniste I et al. | Immunochemical characterization of NADPH-cytochrome P-450 reductase from Jerusalem artichoke and other higher plants. | 1989 | Biochem. J. | pmid:2499315 |
Fink AS et al. | Intraluminal calcium binding does not mediate fatty acid-induced pancreatic bicarbonate secretion. | 1989 | Int. J. Pancreatol. | pmid:2499642 |
Pham MA et al. | Characterization of distinct forms of cytochromes P-450, epoxide metabolizing enzymes and UDP-glucuronosyltransferases in rat skin. | 1989 | Biochem. Pharmacol. | pmid:2500129 |
Murai T et al. | Effect of beraprost sodium on peripheral circulation insufficiency in rats and rabbits. | 1989 | Arzneimittelforschung | pmid:2510741 |
Adarchenko AA et al. | [Antiseptic sensitivity of clinical strains of Pseudomonas aeruginosa]. | 1989 | Antibiot. Khimioter. | pmid:2517004 |
Thomas H et al. | Effect of hypolipidemic compounds on lauric acid hydroxylation and phase II enzymes. | 1989 | Biochem. Pharmacol. | pmid:2500933 |
Uno T and Imai Y | Identification of regions functioning in substrate interaction of rabbit liver cytochrome P-450 (laurate (omega-1)-hydroxylase). | 1989 | J. Biochem. | pmid:2691506 |
Boiteux-Antoine AF et al. | Comparative induction of drug-metabolizing enzymes by hypolipidaemic compounds. | 1989 | Gen. Pharmacol. | pmid:2502468 |
Tambo F et al. | Auto-oxidation of Lingula unguis and Siphonosoma cumanense hemerythrins induced by some perturbants. | 1989 | Biochem. Int. | pmid:2764951 |
Thomas OR and White GF | Metabolic pathway for the biodegradation of sodium dodecyl sulfate by Pseudomonas sp. C12B. | 1989 | Biotechnol. Appl. Biochem. | pmid:2503014 |
Sharma RK et al. | Differential induction of peroxisomal and microsomal fatty-acid-oxidising enzymes by peroxisome proliferators in rat liver and kidney. Characterisation of a renal cytochrome P-450 and implications for peroxisome proliferation. | 1989 | Eur. J. Biochem. | pmid:2776771 |
Green PG et al. | Enhanced in vitro skin permeation of cationic drugs. | 1989 | Pharm. Res. | pmid:2798314 |
Ohhira S and Matsui H | [Determination of dibutyltin compounds in polyvinyl chloride resin by capillary gas chromatography]. | 1989 | Nihon Eiseigaku Zasshi | pmid:2746975 |
Imaoka S et al. | Omega- and (omega-1)-hydroxylation of lauric acid and arachidonic acid by rat renal cytochrome P-450. | 1989 | Biochem. Int. | pmid:2504167 |
Wong KL et al. | Dietary cis-fatty acids that increase protein F1 phosphorylation enhance spatial memory. | 1989 | Brain Res. | pmid:2598047 |
Stucki JW et al. | Acylation of proteins by myristic acid in isolated mitochondria. | 1989 | J. Biol. Chem. | pmid:2703494 |
Bugaut M | In vivo incorporation of lauric acid into rat adipose tissue triacylglycerols. | 1989 | Lipids | pmid:2761351 |
Leakey JE et al. | Effects of aging and caloric restriction on hepatic drug metabolizing enzymes in the Fischer 344 rat. I: The cytochrome P-450 dependent monooxygenase system. | 1989 | Mech. Ageing Dev. | pmid:2661932 |
Sanglard D and Loper JC | Characterization of the alkane-inducible cytochrome P450 (P450alk) gene from the yeast Candida tropicalis: identification of a new P450 gene family. | 1989 | Gene | pmid:2663647 |
Frolov AF et al. | Fatty acid composition of lipopolysaccharides of the strains of different species of Yersinia. | 1989 | J Hyg Epidemiol Microbiol Immunol | pmid:2723424 |
Muerhoff AS et al. | Prostaglandin and fatty acid omega- and (omega-1)-oxidation in rabbit lung. Acetylenic fatty acid mechanism-based inactivators as specific inhibitors. | 1989 | J. Biol. Chem. | pmid:2910864 |
Khan S et al. | Effect of a Prudhoe Bay crude oil on hepatic and renal peroxisomal beta-oxidation and mixed-function oxidase activities in rats. | 1989 | Carcinogenesis | pmid:2912577 |
Menke G et al. | Kinetics of drug binding to human serum albumin: allosteric and competitive inhibition at the benzodiazepine binding site by free fatty acids of various chain lengths. | 1989 Jan-Feb | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:2471088 |
Yamazaki M et al. | The effect of fatty acids on the rectal absorption of acyclovir in rats. | 1990 | J. Pharm. Pharmacol. | pmid:1979629 |
Radom J et al. | Influence of chain length of pyrene fatty acids on their uptake and metabolism by Epstein-Barr-virus-transformed lymphoid cell lines from a patient with multisystemic lipid storage myopathy and from control subjects. | 1990 | Biochem. J. | pmid:2165389 |
Ogiso T and Shintani M | Mechanism for the enhancement effect of fatty acids on the percutaneous absorption of propranolol. | 1990 | J Pharm Sci | pmid:2079652 |
Bergman T and Postlind H | Characterization of pig kidney microsomal cytochrome P-450 catalysing 25-hydroxylation of vitamin D3 and C27 steroids. | 1990 | Biochem. J. | pmid:2169238 |
Sauer G et al. | Systemic treatment of a human epidermoid non-small cell lung carcinoma xenograft with a xanthate compound causes extensive intratumoral necrosis. | 1990 | Cancer Lett. | pmid:2170004 |
Pedersen AO et al. | Thermodynamic parameters for binding of fatty acids to human serum albumin. | 1990 | Eur. J. Biochem. | pmid:2373077 |
Mensink RP and Katan MB | Effect of dietary trans fatty acids on high-density and low-density lipoprotein cholesterol levels in healthy subjects. | 1990 | N. Engl. J. Med. | pmid:2374566 |
Hickey AJ et al. | Effect of hydrophobic coating on the behavior of a hygroscopic aerosol powder in an environment of controlled temperature and relative humidity. | 1990 | J Pharm Sci | pmid:2292762 |
Aoyama T et al. | Clofibrate-inducible rat hepatic P450s IVA1 and IVA3 catalyze the omega- and (omega-1)-hydroxylation of fatty acids and the omega-hydroxylation of prostaglandins E1 and F2 alpha. | 1990 | J. Lipid Res. | pmid:2280187 |
Boddupalli SS et al. | Fatty acid monooxygenation by cytochrome P-450BM-3. | 1990 | J. Biol. Chem. | pmid:2407733 |
Brozek KA and Raetz CR | Biosynthesis of lipid A in Escherichia coli. Acyl carrier protein-dependent incorporation of laurate and myristate. | 1990 | J. Biol. Chem. | pmid:2203778 |
Miranda CL et al. | Regiospecificity in the hydroxylation of lauric acid by rainbow trout hepatic cytochrome P450 isozymes. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2403346 |
Nakamura J et al. | Effect of straight chain fatty acids on seizures induced by picrotoxin and pentylenetetrazole in mice. | 1990 | J. Pharmacobio-dyn. | pmid:2341972 |
Bergeron N et al. | Interaction between dietary proteins and lipids in the regulation of serum and liver lipids in the rabbit. Effect of fish protein. | 1991 | Lipids | pmid:1762524 |
Hare WR and Wahle KW | The participation of soluble factors in the omega-oxidation of fatty acids in the liver of the sheep. | 1991 | Lipids | pmid:2051891 |
Giera DD and van Lier RB | A convenient method for the determination of hepatic lauric acid omega-oxidation based on solvent partition. | 1991 | Fundam Appl Toxicol | pmid:2055365 |
Nordström T et al. | Inhibition of CD3-induced Ca2+ signals in Jurkat T-cells by myristic acid. | 1991 | Cell Calcium | pmid:1834341 |
Ogiso T et al. | Enhancement effect of lauric acid on the rectal absorption of propranolol from suppository in rats. | 1991 | Chem. Pharm. Bull. | pmid:1806286 |
Watanabe T et al. | Co-suppression by nicardipine, a calcium antagonist, of induction of microsomal lauric acid hydroxylation with peroxisome proliferation in clofibrate-treated rat liver. | 1991 | Chem. Pharm. Bull. | pmid:1914008 |
Hara H et al. | Effect of (+/-)-2-(dimethylamino)-1-[[o-(m-methoxyphenethyl)phenoxy] methyl]ethyl hydrogen succinate on experimental models of peripheral obstructive disease. | 1991 | Arzneimittelforschung | pmid:1930349 |
Swinney DC et al. | A novel rat hepatic clofibrate-inducible cytochrome P450 that is not a lauric acid hydroxylase. | 1991 | Biochem. Pharmacol. | pmid:1662512 |
Ogiso T et al. | Enhancement by fatty acids of the rectal absorption of propranolol: in vitro evaluation in the rat. | 1991 | J. Pharmacobio-dyn. | pmid:1802986 |
Yamada J et al. | Assay of fatty acid omega-hydroxylation using high-performance liquid chromatography with fluorescence labeling reagent, 3-bromomethyl-7-methoxy-1,4-benzoxazin-2-one (BrMB). | 1991 | Anal. Biochem. | pmid:1839651 |
Dirven HA et al. | Determination of the cytochrome P-450 IV marker, omega-hydroxylauric acid, by high-performance liquid chromatography and fluorimetric detection. | 1991 | J. Chromatogr. | pmid:1860919 |
Maurich V et al. | p-nitrophenyllaurate: a substrate for the high-performance liquid chromatographic determination of lipase activity. | 1991 | J. Chromatogr. | pmid:1939456 |
Salerno JW and Smith DE | The use of sesame oil and other vegetable oils in the inhibition of human colon cancer growth in vitro. | 1991 Jan-Feb | Anticancer Res. | pmid:2018355 |
Hvattum E et al. | Microsomal oxidation of dodecylthioacetic acid (a 3-thia fatty acid) in rat liver. | 1991 Mar 15-Apr 1 | Biochem. Pharmacol. | pmid:1672593 |