MeSH term | MeSH ID | Detail |
---|---|---|
Bird Diseases | D001715 | 4 associated lipids |
Albuminuria | D000419 | 18 associated lipids |
Acne Vulgaris | D000152 | 35 associated lipids |
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with lauric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Rietschel ET et al. | Chemical structure and biologic activity of bacterial and synthetic lipid A. | 1987 Sep-Oct | Rev. Infect. Dis. | pmid:3317748 |
Stanislawski L et al. | Hybridoma antibodies to the lipid-binding site(s) in the amino-terminal region of fibronectin inhibits binding of streptococcal lipoteichoic acid. | 1987 | J. Infect. Dis. | pmid:3298457 |
Imai Y | Characterization of rabbit liver cytochrome P-450 (laurate omega-1 hydroxylase) synthesized in transformed yeast cells. | 1988 | J. Biochem. | pmid:3283112 |
Ikeda T et al. | Induction of peroxisome proliferation in rat liver by dietary treatment with 2,2,4,4,6,8,8-heptamethylnonane. | 1988 | Xenobiotica | pmid:3245225 |
Fibach E et al. | Flow cytofluorometric analysis of the uptake of the fluorescent fatty acid pyrene-dodecanoic acid by human peripheral blood cells. | 1988 | Cytometry | pmid:3208618 |
CaJacob CA et al. | The catalytic site of rat hepatic lauric acid omega-hydroxylase. Protein versus prosthetic heme alkylation in the omega-hydroxylation of acetylenic fatty acids. | 1988 | J. Biol. Chem. | pmid:3198593 |
Goldberg M et al. | Enzymatic ester synthesis with continuous measurement of water activity. | 1988 | Biochim. Biophys. Acta | pmid:3196717 |
Lorenzana RM et al. | Localization of cytochrome P-450 in the head and trunk kidney of rainbow trout (Salmo gairdneri). | 1988 | Toxicol. Appl. Pharmacol. | pmid:3188021 |
Andreiuk GM and Kiselev PA | [Initiation of lipid peroxidation as a result of hemoglobin transformation into hemichrome induced by free fatty acids]. | 1988 | Biokhimiia | pmid:3179347 |
Csordas A and Rybczynska M | Critical temperatures for the interaction of free fatty acids with the erythrocyte membrane. | 1988 | Biochim. Biophys. Acta | pmid:3179287 |
Honoré B et al. | Cobinding of bilirubin and laurate to human serum albumin: spectroscopic characterization of stoichiometric complexes. | 1988 | Arch. Biochem. Biophys. | pmid:3178221 |
Donbrow M et al. | Autoxidation of polysorbates. | 1978 | J Pharm Sci | pmid:31449 |
Kiffel L et al. | Purification and characterization of a cytochrome P-450 isozyme isolated from the liver of rats pretreated with clofibrate. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3140811 |
Qureshi N et al. | Complete structural determination of lipopolysaccharide obtained from deep rough mutant of Escherichia coli. Purification by high performance liquid chromatography and direct analysis by plasma desorption mass spectrometry. | 1988 | J. Biol. Chem. | pmid:3136169 |
Imai Y and Nakamura M | The importance of threonine-301 from cytochromes P-450 (laurate (omega-1)-hydroxylase and testosterone 16 alpha-hydroxylase) in substrate binding as demonstrated by site-directed mutagenesis. | 1988 | FEBS Lett. | pmid:3134259 |
Eriksson LO and Boström H | Deactivation of sulindac-sulphide by human renal microsomes. | 1988 | Pharmacol. Toxicol. | pmid:3133648 |
Sumimoto J et al. | Characterization of human neutrophil leukotriene B4 omega-hydroxylase as a system involving a unique cytochrome P-450 and NADPH-cytochrome P-450 reductase. | 1988 | Eur. J. Biochem. | pmid:3127205 |
Albro PW et al. | Rapid isolation of microsomes for studies of lipid peroxidation. | 1987 | Lipids | pmid:3123838 |
Fournel S et al. | Stereospecificity of enzyme induction by 2-phenylpropionic acid. | 1987 | Pharmacol. Ther. | pmid:3114776 |
Leyton J et al. | Differential oxidation of saturated and unsaturated fatty acids in vivo in the rat. | 1987 | Br. J. Nutr. | pmid:3109464 |
Elcombe CR and Mitchell AM | Peroxisome proliferation due to di(2-ethylhexyl) phthalate (DEHP): species differences and possible mechanisms. | 1986 | Environ. Health Perspect. | pmid:3104023 |
Rose RC | Solubility properties of reduced and oxidized ascorbate as determinants of membrane permeation. | 1987 | Biochim. Biophys. Acta | pmid:3103695 |
Raza H and Levine WG | Effect of hypolipidemic drugs on the metabolism of lauric acid and dimethylaminoazobenzene by rat liver microsomes. | 1987 | Biochem. Pharmacol. | pmid:3103631 |
Miura Y et al. | omega- and (omega--1)-hydroxylation of fatty acids by frog liver microsomes. Substrate specificity and other properties. | 1978 | Biochim. Biophys. Acta | pmid:309772 |
Levine WG and Raza H | Clofibrate selectively induces azoreduction of dimethylaminoazobenzene (DAB) by rat liver microsomes. | 1986 | Adv. Exp. Med. Biol. | pmid:3094343 |
Ohashi M et al. | Anti-thrombotic effect of KC-404, a novel cerebral vasodilator. | 1986 | Gen. Pharmacol. | pmid:3093313 |
Fournel S et al. | Stereospecific induction of rat liver bilirubin UDPglucuronosyltransferase and lauric acid 12-hydroxylation by the isomers of 2-phenylpropionic acid. | 1986 | Biochim. Biophys. Acta | pmid:3089296 |
Lehmann V and Benninghoff B | Isolation of a mutant from Salmonella typhimurium producing acyl-deficient lipopolysaccharides. | 1988 | Eur. J. Biochem. | pmid:3061817 |
Gergely J | [S. Tonegawa, 1987 Nobel Prize laureate in medicine]. | 1988 | Orv Hetil | pmid:3050756 |
Miura Y | Effects of in vivo administration of detergents on the hepatic microsomal cytochrome P-450 system in rat. | 1987 | J Appl Toxicol | pmid:3040845 |
Tanaka T et al. | Saturated and trans-unsaturated fatty acids elicit high levels of superoxide generation in intact and cell-free preparations of neutrophils. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3034258 |
Romano MC et al. | Biochemical characterization of hepatic microsomal leukotriene B4 hydroxylases. | 1987 | J. Biol. Chem. | pmid:3027095 |
Dailey MO et al. | Induction of cell-mediated immunity to chemically modified antigens in guinea pigs. II. The interaction between lipid-conjugated antigens, macrophages, and T lymphocytes. | 1977 | J. Immunol. | pmid:300393 |
Cometti A et al. | Isolation and structure determination of the main related substances of teicoplanin, a glycopeptide antibiotic. | 1988 | Farmaco Sci | pmid:2977757 |
Khan S et al. | Effect of a Prudhoe Bay crude oil on hepatic and renal peroxisomal beta-oxidation and mixed-function oxidase activities in rats. | 1989 | Carcinogenesis | pmid:2912577 |
Muerhoff AS et al. | Prostaglandin and fatty acid omega- and (omega-1)-oxidation in rabbit lung. Acetylenic fatty acid mechanism-based inactivators as specific inhibitors. | 1989 | J. Biol. Chem. | pmid:2910864 |
Levine WG and Raza H | Mechanism of azoreduction of dimethylaminoazobenzene by rat liver NADPH-cytochrome P-450 reductase and partially purified cytochrome P-450. Oxygen and carbon monoxide sensitivity and stimulation by FAD and FMN. | 1988 May-Jun | Drug Metab. Dispos. | pmid:2900738 |
Alam MS et al. | Influence of di-butyltin dilaurate on brain neurotransmitter systems and behavior in rats. | 1988 | Arch. Toxicol. | pmid:2899427 |
Fournel S et al. | Differential induction profile of drug-metabolizing enzymes after treatment with hypolipidaemic agents. | 1987 | Xenobiotica | pmid:2885979 |
Harsfalvi J et al. | Lipids associated with tissue transglutaminase. | 1987 | Biochim. Biophys. Acta | pmid:2879570 |
Yi M et al. | Expression of CYP4V2 in human THP1 macrophages and its transcriptional regulation by peroxisome proliferator-activated receptor gamma. | 2017 | Toxicol. Appl. Pharmacol. | pmid:28729181 |
Raza H and Levine WG | Azoreduction of N,N-dimethyl-4-aminoazobenzene (DAB) by rat hepatic microsomes. Selective induction by clofibrate. | 1986 Jan-Feb | Drug Metab. Dispos. | pmid:2868860 |
Miura Y | Seasonal change and sex difference in laurate hydroxylase activity in frog liver microsomes. | 1985 | Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. | pmid:2865076 |
Anis SNS et al. | In vivo and in vitro depolymerizations of intracellular medium-chain-length poly-3-hydroxyalkanoates produced by Pseudomonas putida Bet001. | 2017 | Prep. Biochem. Biotechnol. | pmid:28635367 |
Poller JM et al. | Selection of potential iron oxide nanoparticles for breast cancer treatment based on in vitro cytotoxicity and cellular uptake. | 2017 | Int J Nanomedicine | pmid:28458541 |
Dahlbäck H and Wikvall K | 25-Hydroxylation of vitamin D3 by a cytochrome P-450 from rabbit liver mitochondria. | 1988 | Biochem. J. | pmid:2844144 |
Tanaka T et al. | Activation by saturated and monounsaturated fatty acids of the O2- -generating system in a cell-free preparation from neutrophils. | 1988 | J. Biol. Chem. | pmid:2843528 |
Zeiger K et al. | Lauric acid as feed additive - An approach to reducing Campylobacter spp. in broiler meat. | 2017 | PLoS ONE | pmid:28419122 |
Magdalou J et al. | Effect of 1-benzylimidazole on cytochromes P-450 induction and on the activities of epoxide hydrolases and UDP-glucuronosyltransferases in rat liver. | 1988 | Biochem. Pharmacol. | pmid:2840913 |
Dev Kumar G and Micallef SA | Susceptibility of Salmonella enterica Isolates from Tomato Farm Environments to Fatty Acids Naturally Found on Tomato Fruit. | 2017 | Foodborne Pathog. Dis. | pmid:28398868 |