MeSH term | MeSH ID | Detail |
---|---|---|
Bird Diseases | D001715 | 4 associated lipids |
Albuminuria | D000419 | 18 associated lipids |
Acne Vulgaris | D000152 | 35 associated lipids |
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with lauric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Christensen E et al. | Beta-oxidation of medium chain (C8-C14) fatty acids studied in isolated liver cells. | 1989 | Biochim. Biophys. Acta | pmid:2752017 |
Wada M et al. | Mechanism of biosynthesis of unsaturated fatty acids in Pseudomonas sp. strain E-3, a psychrotrophic bacterium. | 1989 | J. Bacteriol. | pmid:2753856 |
Ryals PE et al. | Lipid modification during cytodifferentiation of Tetrahymena vorax. Whole cell phospholipids and triacylglycerols of microstomal and macrostomal phenotypes. | 1989 | Biochim. Biophys. Acta | pmid:2730920 |
Sharma RK et al. | Role of hepatic and renal cytochrome P-450 IVA1 in the metabolism of lipid substrates. | 1989 | Biochem. Pharmacol. | pmid:2554928 |
Makowska JM et al. | Species differences in the hepatic response to a potent peroxisome proliferator. | 1989 | Biochem. Soc. Trans. | pmid:2628085 |
Laignelet L et al. | Induction and inhibition of rat liver cytochrome(s) P-450 by an imidazole fungicide (prochloraz). | 1989 | Toxicology | pmid:2631296 |
Jarabak R and Westley J | The sulfur-cyanolysis sites of serum albumin: metabolite competition studies. | 1989 | J. Biochem. Toxicol. | pmid:2634097 |
Fibach E et al. | Analysis of cellular heterogeneity in the response of human leukemic cells to photosensitization induced by pyrene-containing fatty acid. | 1989 | Leuk. Res. | pmid:2559259 |
Yokotani N et al. | Two forms of omega-hydroxylase toward prostaglandin A and laurate. cDNA cloning and their expression. | 1989 | J. Biol. Chem. | pmid:2600085 |
Khodari M et al. | Applications in drug analysis of carbon paste electrodes modified by fatty acids. | 1989 | J Pharm Biomed Anal | pmid:2490534 |
Imai Y and Nakamura M | Point mutations at threonine-301 modify substrate specificity of rabbit liver microsomal cytochromes P-450 (laurate (omega-1)-hydroxylase and testosterone 16 alpha-hydroxylase). | 1989 | Biochem. Biophys. Res. Commun. | pmid:2493247 |
Borlakoglu JT et al. | Evidence for the induction of cytochrome P-452 in rat liver by Aroclor 1254, a commercial mixture of polychlorinated biphenyls. | 1989 | FEBS Lett. | pmid:2497034 |
Aarsaether N et al. | Changes in peroxisomes and mitochondria in liver of ethionine exposed rats: a biochemical and morphological investigation. | 1989 | Carcinogenesis | pmid:2498002 |
Lake BG et al. | Comparative studies on nafenopin-induced hepatic peroxisome proliferation in the rat, Syrian hamster, guinea pig, and marmoset. | 1989 | Toxicol. Appl. Pharmacol. | pmid:2499080 |
Benveniste I et al. | Immunochemical characterization of NADPH-cytochrome P-450 reductase from Jerusalem artichoke and other higher plants. | 1989 | Biochem. J. | pmid:2499315 |
Fink AS et al. | Intraluminal calcium binding does not mediate fatty acid-induced pancreatic bicarbonate secretion. | 1989 | Int. J. Pancreatol. | pmid:2499642 |
Pham MA et al. | Characterization of distinct forms of cytochromes P-450, epoxide metabolizing enzymes and UDP-glucuronosyltransferases in rat skin. | 1989 | Biochem. Pharmacol. | pmid:2500129 |
Murai T et al. | Effect of beraprost sodium on peripheral circulation insufficiency in rats and rabbits. | 1989 | Arzneimittelforschung | pmid:2510741 |
Adarchenko AA et al. | [Antiseptic sensitivity of clinical strains of Pseudomonas aeruginosa]. | 1989 | Antibiot. Khimioter. | pmid:2517004 |
Uno T and Imai Y | Identification of regions functioning in substrate interaction of rabbit liver cytochrome P-450 (laurate (omega-1)-hydroxylase). | 1989 | J. Biochem. | pmid:2691506 |
Muerhoff AS et al. | Prostaglandin and fatty acid omega- and (omega-1)-oxidation in rabbit lung. Acetylenic fatty acid mechanism-based inactivators as specific inhibitors. | 1989 | J. Biol. Chem. | pmid:2910864 |
Khan S et al. | Effect of a Prudhoe Bay crude oil on hepatic and renal peroxisomal beta-oxidation and mixed-function oxidase activities in rats. | 1989 | Carcinogenesis | pmid:2912577 |
Menke G et al. | Kinetics of drug binding to human serum albumin: allosteric and competitive inhibition at the benzodiazepine binding site by free fatty acids of various chain lengths. | 1989 Jan-Feb | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:2471088 |
Yamazaki M et al. | The effect of fatty acids on the rectal absorption of acyclovir in rats. | 1990 | J. Pharm. Pharmacol. | pmid:1979629 |
Radom J et al. | Influence of chain length of pyrene fatty acids on their uptake and metabolism by Epstein-Barr-virus-transformed lymphoid cell lines from a patient with multisystemic lipid storage myopathy and from control subjects. | 1990 | Biochem. J. | pmid:2165389 |
Ogiso T and Shintani M | Mechanism for the enhancement effect of fatty acids on the percutaneous absorption of propranolol. | 1990 | J Pharm Sci | pmid:2079652 |
Bergman T and Postlind H | Characterization of pig kidney microsomal cytochrome P-450 catalysing 25-hydroxylation of vitamin D3 and C27 steroids. | 1990 | Biochem. J. | pmid:2169238 |
Sauer G et al. | Systemic treatment of a human epidermoid non-small cell lung carcinoma xenograft with a xanthate compound causes extensive intratumoral necrosis. | 1990 | Cancer Lett. | pmid:2170004 |
Pedersen AO et al. | Thermodynamic parameters for binding of fatty acids to human serum albumin. | 1990 | Eur. J. Biochem. | pmid:2373077 |
Mensink RP and Katan MB | Effect of dietary trans fatty acids on high-density and low-density lipoprotein cholesterol levels in healthy subjects. | 1990 | N. Engl. J. Med. | pmid:2374566 |
Hickey AJ et al. | Effect of hydrophobic coating on the behavior of a hygroscopic aerosol powder in an environment of controlled temperature and relative humidity. | 1990 | J Pharm Sci | pmid:2292762 |
Aoyama T et al. | Clofibrate-inducible rat hepatic P450s IVA1 and IVA3 catalyze the omega- and (omega-1)-hydroxylation of fatty acids and the omega-hydroxylation of prostaglandins E1 and F2 alpha. | 1990 | J. Lipid Res. | pmid:2280187 |
Boddupalli SS et al. | Fatty acid monooxygenation by cytochrome P-450BM-3. | 1990 | J. Biol. Chem. | pmid:2407733 |
Brozek KA and Raetz CR | Biosynthesis of lipid A in Escherichia coli. Acyl carrier protein-dependent incorporation of laurate and myristate. | 1990 | J. Biol. Chem. | pmid:2203778 |
Miranda CL et al. | Regiospecificity in the hydroxylation of lauric acid by rainbow trout hepatic cytochrome P450 isozymes. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2403346 |
Nakamura J et al. | Effect of straight chain fatty acids on seizures induced by picrotoxin and pentylenetetrazole in mice. | 1990 | J. Pharmacobio-dyn. | pmid:2341972 |
Bergeron N et al. | Interaction between dietary proteins and lipids in the regulation of serum and liver lipids in the rabbit. Effect of fish protein. | 1991 | Lipids | pmid:1762524 |
Hare WR and Wahle KW | The participation of soluble factors in the omega-oxidation of fatty acids in the liver of the sheep. | 1991 | Lipids | pmid:2051891 |
Giera DD and van Lier RB | A convenient method for the determination of hepatic lauric acid omega-oxidation based on solvent partition. | 1991 | Fundam Appl Toxicol | pmid:2055365 |
Nordström T et al. | Inhibition of CD3-induced Ca2+ signals in Jurkat T-cells by myristic acid. | 1991 | Cell Calcium | pmid:1834341 |
Ogiso T et al. | Enhancement effect of lauric acid on the rectal absorption of propranolol from suppository in rats. | 1991 | Chem. Pharm. Bull. | pmid:1806286 |
Watanabe T et al. | Co-suppression by nicardipine, a calcium antagonist, of induction of microsomal lauric acid hydroxylation with peroxisome proliferation in clofibrate-treated rat liver. | 1991 | Chem. Pharm. Bull. | pmid:1914008 |
Hara H et al. | Effect of (+/-)-2-(dimethylamino)-1-[[o-(m-methoxyphenethyl)phenoxy] methyl]ethyl hydrogen succinate on experimental models of peripheral obstructive disease. | 1991 | Arzneimittelforschung | pmid:1930349 |
Swinney DC et al. | A novel rat hepatic clofibrate-inducible cytochrome P450 that is not a lauric acid hydroxylase. | 1991 | Biochem. Pharmacol. | pmid:1662512 |
Ogiso T et al. | Enhancement by fatty acids of the rectal absorption of propranolol: in vitro evaluation in the rat. | 1991 | J. Pharmacobio-dyn. | pmid:1802986 |
Yamada J et al. | Assay of fatty acid omega-hydroxylation using high-performance liquid chromatography with fluorescence labeling reagent, 3-bromomethyl-7-methoxy-1,4-benzoxazin-2-one (BrMB). | 1991 | Anal. Biochem. | pmid:1839651 |
Dirven HA et al. | Determination of the cytochrome P-450 IV marker, omega-hydroxylauric acid, by high-performance liquid chromatography and fluorimetric detection. | 1991 | J. Chromatogr. | pmid:1860919 |
Maurich V et al. | p-nitrophenyllaurate: a substrate for the high-performance liquid chromatographic determination of lipase activity. | 1991 | J. Chromatogr. | pmid:1939456 |
Salerno JW and Smith DE | The use of sesame oil and other vegetable oils in the inhibition of human colon cancer growth in vitro. | 1991 Jan-Feb | Anticancer Res. | pmid:2018355 |
Hvattum E et al. | Microsomal oxidation of dodecylthioacetic acid (a 3-thia fatty acid) in rat liver. | 1991 Mar 15-Apr 1 | Biochem. Pharmacol. | pmid:1672593 |