MeSH term | MeSH ID | Detail |
---|---|---|
Nephrosis, Lipoid | D009402 | 2 associated lipids |
Carotid Artery Injuries | D020212 | 8 associated lipids |
Vascular System Injuries | D057772 | 2 associated lipids |
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with lauric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Blomqvist M et al. | Uptake of the glycosphingolipid sulfatide in the gastrointestinal tract and pancreas in vivo and in isolated islets of Langerhans. | 2006 | Lipids Health Dis | pmid:17044925 |
Pronczuk A et al. | Plasma lipids are affected similarly by dietary lauric or palmitic acid in gerbils and monkeys. | 1995 | Lipids | pmid:8614307 |
Valdes E et al. | Dietary fish oil and cytochrome P-450 monooxygenase activity in rat liver and kidney. | 1995 | Lipids | pmid:8538384 |
Tsai YH et al. | Mechanisms mediating lipoprotein responses to diets with medium-chain triglyceride and lauric acid. | 1999 | Lipids | pmid:10574653 |
Cazeils JL et al. | Lipid composition of hepatocyte plasma membranes from geese overfed with corn. | 1999 | Lipids | pmid:10574658 |
Miura Y et al. | Hydroxylation of fatty acids and alcohols by hepatic microsomal cytochrome P-450 system from the Mongolian gerbil. | 1987 | Lipids | pmid:3451012 |
German JB and Dillard CJ | Saturated fats: a perspective from lactation and milk composition. | 2010 | Lipids | pmid:20652757 |
Legrand P and Rioux V | The complex and important cellular and metabolic functions of saturated fatty acids. | 2010 | Lipids | pmid:20625935 |
Bergeron N et al. | Interaction between dietary proteins and lipids in the regulation of serum and liver lipids in the rabbit. Effect of fish protein. | 1991 | Lipids | pmid:1762524 |
Miura Y | Omega- and (omega-1)-hydroxylation of 1-dodecanol by frog liver microsomes. | 1981 | Lipids | pmid:6975411 |
Miura Y | Effect of inhibitors on omega- and (omega-1)-hydroxylation of lauric acid by frog liver microsomes. | 1982 | Lipids | pmid:6984479 |
Lemaire P et al. | Subterminal hydroxylation of lauric acid by microsomes from a marine fish. | 1992 | Lipids | pmid:1522763 |
Beermann C et al. | Comparison of the structures of triacylglycerols from native and transgenic medium-chain fatty acid-enriched rape seed oil by liquid chromatography--atmospheric pressure chemical ionization ion-trap mass spectrometry (LC-APCI-ITMS). | 2007 | Lipids | pmid:17406932 |
Legrand P et al. | Short chain saturated fatty acids decrease circulating cholesterol and increase tissue PUFA content in the rat. | 2010 | Lipids | pmid:20924709 |
Akesson B et al. | Absorption of synthetic, stereochemically defined acylglycerols in the rat. | 1978 | Lipids | pmid:672470 |
Hare WR and Wahle KW | The participation of soluble factors in the omega-oxidation of fatty acids in the liver of the sheep. | 1991 | Lipids | pmid:2051891 |
Tsuzuki W | Absorption properties of micellar lipid metabolites into Caco2 cells. | 2007 | Lipids | pmid:17582542 |
Kothari HV | Purification and properties of aortic cholesteryl ester hydrolase. | 1975 | Lipids | pmid:1134220 |
Bugaut M | In vivo incorporation of lauric acid into rat adipose tissue triacylglycerols. | 1989 | Lipids | pmid:2761351 |
Albro PW et al. | Rapid isolation of microsomes for studies of lipid peroxidation. | 1987 | Lipids | pmid:3123838 |
Micha R and Mozaffarian D | Saturated fat and cardiometabolic risk factors, coronary heart disease, stroke, and diabetes: a fresh look at the evidence. | 2010 | Lipids | pmid:20354806 |
Legrand P et al. | Lauric acid is desaturated to 12:1n-3 by hepatocytes and rat liver homogenates. | 2002 | Lipids | pmid:12120955 |
Carballeira NM et al. | Synthesis of a novel series of 2-methylsulfanyl fatty acids and their toxicity on the human K-562 and U-937 leukemia cell lines. | 2005 | Lipids | pmid:16382579 |
Lake BG et al. | Induction of lauric acid hydroxylation and maintenance of cytochrome P-450 content by clofibrate in primary cultures of rat hepatocytes. | 1983 | Life Sci. | pmid:6865658 |
Lake BG et al. | The effect of peroxisome proliferators on the metabolism and spectral interaction of endogenous substrates of cytochrome P-450 in rat hepatic microsomes. | 1984 | Life Sci. | pmid:6439971 |
Sasame HA et al. | The possible involvement of cytochrome b5 in the oxidation of lauric acid by microsomes from kidney cortex and liver of rats. | 1974 | Life Sci. | pmid:4129689 |
Piver B et al. | Differential inhibition of human cytochrome P450 enzymes by epsilon-viniferin, the dimer of resveratrol: comparison with resveratrol and polyphenols from alcoholized beverages. | 2003 | Life Sci. | pmid:12818727 |
Mukwevho E and Joseph JS | Calmodulin dependent protein kinase II activation by exercise regulates saturated & unsaturated fatty acids and improves some metabolic syndrome markers. | 2014 | Life Sci. | pmid:25046734 |
Bagasra O et al. | The Libyan HIV Outbreak How do we find the truth? | 2007 | Libyan J Med | pmid:21503253 |
Fibach E and Gatt S | Clonal analysis of the response of human promyelocytic leukemia (HL-60) cells to photosensitization induced by a pyrene-containing fatty acid. | 1987 | Leuk. Res. | pmid:3480396 |
Fibach E et al. | Analysis of cellular heterogeneity in the response of human leukemic cells to photosensitization induced by pyrene-containing fatty acid. | 1989 | Leuk. Res. | pmid:2559259 |
Soliva CR et al. | Effects of mixtures of lauric and myristic acid on rumen methanogens and methanogenesis in vitro. | 2003 | Lett. Appl. Microbiol. | pmid:12803553 |
Skrivanová E et al. | Susceptibility of Clostridium perfringens to C-C fatty acids. | 2005 | Lett. Appl. Microbiol. | pmid:15960756 |
Chen Y et al. | Antilisterial activity of lactose monolaurate in milk, drinkable yogurt and cottage cheese. | 2014 | Lett. Appl. Microbiol. | pmid:24117896 |
Liangqi Z et al. | Synthesis of poly (3-hydroxybutyrate-co-3-hydroxyoctanoate) by a Sinorhizobium fredii strain. | 2006 | Lett. Appl. Microbiol. | pmid:16599986 |
Brunner G | [Progress on the way to an "artificial liver"]. | 1984 | Leber Magen Darm | pmid:6513719 |
Li H et al. | Phase transition in salt-free catanionic surfactant mixtures induced by temperature. | 2010 | Langmuir | pmid:19810715 |
Shen Y et al. | Phase transition of precipitation cream with densely packed multilamellar vesicles by the replacement of solvent. | 2009 | Langmuir | pmid:19735130 |
Zana R | Partial phase behavior and micellar properties of tetrabutylammonium salts of fatty acids: unusual solubility in water and formation of unexpectedly small micelles. | 2004 | Langmuir | pmid:16459576 |
Vlachy N et al. | Spontaneous formation of bilayers and vesicles in mixtures of single-chain alkyl carboxylates: effect of pH and aging and cytotoxicity studies. | 2008 | Langmuir | pmid:18712886 |
Kim JH et al. | Evaporation of sessile droplets of dilute aqueous solutions containing sodium n-alkylates from polymer surfaces: influences of alkyl length and concentration of solute. | 2008 | Langmuir | pmid:18798660 |
Ponnurangam S et al. | Rational design of interfacial properties of ferric (hydr)oxide nanoparticles by adsorption of fatty acids from aqueous solutions. | 2012 | Langmuir | pmid:22694303 |
Yoon BK et al. | Spectrum of Membrane Morphological Responses to Antibacterial Fatty Acids and Related Surfactants. | 2015 | Langmuir | pmid:26325618 |
Nelson N et al. | Single molecule dynamics on hydrophobic self-assembled monolayers. | 2012 | Langmuir | pmid:22876990 |
Jiang W et al. | Anisotropic ionogels of sodium laurate in a room-temperature ionic liquid. | 2008 | Langmuir | pmid:18294018 |
Roux M et al. | Dynamic lipid lateral segregation driven by lauryl cyclodextrin interactions at the membrane surface. | 2013 | Langmuir | pmid:23409976 |
Totland C et al. | Composition and structural transitions of polyelectrolyte-surfactant complexes in the presence of fatty acid studied by NMR and cryo-SEM. | 2015 | Langmuir | pmid:25590530 |
Sagis LM et al. | Highly stable foams from block oligomers synthesized by enzymatic reactions. | 2008 | Langmuir | pmid:18081334 |
Steinmiller EM and Choi KS | Anodic construction of lamellar structured ZnO films using basic media via interfacial surfactant templating. | 2007 | Langmuir | pmid:17973505 |
Banno T et al. | pH-Sensitive self-propelled motion of oil droplets in the presence of cationic surfactants containing hydrolyzable ester linkages. | 2012 | Langmuir | pmid:22149384 |
Abelev E et al. | Enhanced copper surface protection in aqueous solutions containing short-chain alkanoic acid potassium salts. | 2007 | Langmuir | pmid:17900157 |
Hidalgo Baltasar E et al. | Role of water structure on the high pressure micellization and phase transformations of sodium dodecanoate aqueous solutions. | 2014 | Langmuir | pmid:24903603 |
Pereira RF et al. | Effect of metal ion hydration on the interaction between sodium carboxylates and aluminum(III) or chromium(III) ions in aqueous solution. | 2012 | Langmuir | pmid:22107111 |
Cavalier M et al. | How can the nanocrystallinity of 7 nm spherical Co nanoparticles dispersed in solution be improved? | 2011 | Langmuir | pmid:21413686 |
Paulus M et al. | Sticking polydisperse hydrophobic magnetite nanoparticles to lipid membranes. | 2010 | Langmuir | pmid:20873726 |
Yu SS and Downard AJ | Photochemical grafting and activation of organic layers on glassy carbon and pyrolyzed photoresist films. | 2007 | Langmuir | pmid:17358087 |
Kralchevsky PA et al. | Effect of the precipitation of neutral-soap, acid-soap, and alkanoic acid crystallites on the bulk pH and surface tension of soap solutions. | 2007 | Langmuir | pmid:17319702 |
Chernyshova IV et al. | Adsorption of fatty acids on iron (hydr)oxides from aqueous solutions. | 2011 | Langmuir | pmid:21711036 |
Badre C et al. | Modification of the wettability of a polymeric substrate by pH effect. Determination of the surface acid dissociation constant by contact angle measurements. | 2006 | Langmuir | pmid:16981758 |
Tian H et al. | Effect of hydrophilic groups of Ca surfactants and hydrophobic chains of C(n)DMAO on coordinated vesicle formation. | 2010 | Langmuir | pmid:21087007 |
King DT et al. | Using molecular dynamics to study liquid phase behavior: simulations of the ternary sodium laurate/sodium oleate/water system. | 2011 | Langmuir | pmid:21838286 |
Li H et al. | Reverse vesicles from a salt-free catanionic surfactant system: a confocal fluorescence microscopy study. | 2010 | Langmuir | pmid:20822115 |
De Lisi R et al. | Heat capacity of transfer of (Ethylene oxide)13-(propylene oxide)30-(ethylene oxide)13 from water to the aqueous anionic surfactant solutions at 298 K. A quantitative treatment. | 2004 | Langmuir | pmid:15518478 |
RodrÃguez-Pulido A et al. | Experimental and theoretical approach to the sodium decanoate-dodecanoate mixed surfactant system in aqueous solution. | 2010 | Langmuir | pmid:20462279 |
Mahiuddin S et al. | Catanionic micelles as a model to mimic biological membranes in the presence of anesthetic alcohols. | 2009 | Langmuir | pmid:19856990 |
Nicolaas L et al. | Patellofemoral evaluation with magnetic resonance imaging in 51 knees of asymptomatic subjects. | 2011 | Knee Surg Sports Traumatol Arthrosc | pmid:21533540 |
Gross V et al. | Inhibition of pressure natriuresis in mice lacking the AT2 receptor. | 2000 | Kidney Int. | pmid:10620200 |
Ghiggeri GM et al. | Characterization of cationic albumin in minimal change nephropathy. | 1987 | Kidney Int. | pmid:3430951 |
Shirakura S et al. | Antithrombotic effects of KW-3635, a thromboxane A2-receptor antagonist, in guinea pigs. | 1994 | Jpn. J. Pharmacol. | pmid:7967232 |
Hasumura S et al. | Effects of starvation on microsomal cytochrome P-450 and laurate-omega-hydroxylation of rat kidney and liver. | 1983 | Jpn. J. Pharmacol. | pmid:6645119 |
Miura Y et al. | An analysis of the fatty acid composition of total lipids from mycoplasmas. | 1978 | Jpn. J. Exp. Med. | pmid:750678 |
Sigalet DL et al. | Determination of the route of medium-chain and long-chain fatty acid absorption by direct measurement in the rat. | 1997 Sep-Oct | JPEN J Parenter Enteral Nutr | pmid:9323689 |
Yoon JW and Hovde CJ | All blood, no stool: enterohemorrhagic Escherichia coli O157:H7 infection. | 2008 | J. Vet. Sci. | pmid:18716441 |
Mann RS and Kaufman PE | Colonization of Lutzomyia shannoni (Diptera: Psychodidae) utilizing an artificial blood feeding technique. | 2010 | J. Vector Ecol. | pmid:21175933 |
Kong X et al. | High-mobility-group box protein 1A box reduces development of sodium laurate-induced thromboangiitis obliterans in rats. | 2013 | J. Vasc. Surg. | pmid:23069071 |
Garfinkel M et al. | Insulinotropic potency of lauric acid: a metabolic rationale for medium chain fatty acids (MCF) in TPN formulation. | 1992 | J. Surg. Res. | pmid:1593871 |
Raynaud JP et al. | Inhibition of type 1 and type 2 5alpha-reductase activity by free fatty acids, active ingredients of Permixon. | 2002 | J. Steroid Biochem. Mol. Biol. | pmid:12477490 |
Coimbra MC and Jorge N | Fatty acids and bioactive compounds of the pulps and kernels of Brazilian palm species, guariroba (Syagrus oleraces), jerivá (Syagrus romanzoffiana) and macaúba (Acrocomia aculeata). | 2012 | J. Sci. Food Agric. | pmid:21922463 |
Blum JJ | Effects of osmotic pressure on the oxidative metabolism of Leishmania major promastigotes. | 1991 May-Jun | J. Protozool. | pmid:1679134 |
Wołkow PP and Korbut R | Pharmacology at the Jagiellonian University in Kracow, short review of contribution to global science and cardiovascular research through 400 years of history. | 2006 | J. Physiol. Pharmacol. | pmid:16766803 |
Sidhu SS et al. | Fatty acid-induced cholecystokinin secretion and changes in intracellular Ca2+ in two enteroendocrine cell lines, STC-1 and GLUTag. | 2000 | J. Physiol. (Lond.) | pmid:11018115 |
Feltrin KL et al. | Effects of lauric acid on upper gut motility, plasma cholecystokinin and peptide YY, and energy intake are load, but not concentration, dependent in humans. | 2007 | J. Physiol. (Lond.) | pmid:17331985 |
Benson RS et al. | Fatty acid signalling in a mouse enteroendocrine cell line involves fatty acid aggregates rather than free fatty acids. | 2002 | J. Physiol. (Lond.) | pmid:11773321 |
Kazmi S et al. | Calcium mobilisation and CCK secretion induced by modified fatty acids and latex microspheres reveal dual receptor mechanisms for lipid stimulation of STC-1 cells. | 2003 | J. Physiol. (Lond.) | pmid:14555726 |
Inami Y et al. | Prevention of topical surfactant-induced itch-related responses by chlorogenic acid through the inhibition of increased histamine production in the epidermis. | 2013 | J. Pharmacol. Sci. | pmid:23449492 |
Lindmark T et al. | Absorption enhancement through intracellular regulation of tight junction permeability by medium chain fatty acids in Caco-2 cells. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9435199 |
Cresteil T et al. | Cytochrome P-450 isoenzyme content and monooxygenase activities in rat liver: effect of ontogenesis and pretreatment by phenobarbital and 3-methylcholanthrene. | 1986 | J. Pharmacol. Exp. Ther. | pmid:3941398 |
Inami Y et al. | Topical surfactant-induced pruritus: involvement of histamine released from epidermal keratinocytes. | 2013 | J. Pharmacol. Exp. Ther. | pmid:23220712 |
Wang JS et al. | Transfection and functional expression of CYP4A1 and CYP4A2 using bicistronic vectors in vascular cells and tissues. | 2004 | J. Pharmacol. Exp. Ther. | pmid:15269250 |
Coyne CB et al. | Acute mechanism of medium chain fatty acid-induced enhancement of airway epithelial permeability. | 2003 | J. Pharmacol. Exp. Ther. | pmid:12606647 |
Imaoka S et al. | Identification of CYP2C23 expressed in rat kidney as an arachidonic acid epoxygenase. | 1993 | J. Pharmacol. Exp. Ther. | pmid:8246128 |
Fang X et al. | Activation of peroxisome proliferator-activated receptor alpha by substituted urea-derived soluble epoxide hydrolase inhibitors. | 2005 | J. Pharmacol. Exp. Ther. | pmid:15798002 |
Xu F et al. | Catalytic activity and isoform-specific inhibition of rat cytochrome p450 4F enzymes. | 2004 | J. Pharmacol. Exp. Ther. | pmid:14634044 |
Bumpus NN and Johnson EF | 5-Aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor α-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated protein kinase-independent. | 2011 | J. Pharmacol. Exp. Ther. | pmid:21896918 |
Mishima M et al. | Promotion of nasal absorption of insulin by glycyrrhetinic acid derivatives. I. | 1989 | J. Pharmacobio-dyn. | pmid:2656985 |
Nakamura J et al. | Effect of straight chain fatty acids on seizures induced by picrotoxin and pentylenetetrazole in mice. | 1990 | J. Pharmacobio-dyn. | pmid:2341972 |
Ogiso T et al. | Enhancement by fatty acids of the rectal absorption of propranolol: in vitro evaluation in the rat. | 1991 | J. Pharmacobio-dyn. | pmid:1802986 |
Yamazaki M et al. | The effect of fatty acids on the rectal absorption of acyclovir in rats. | 1990 | J. Pharm. Pharmacol. | pmid:1979629 |
Kim T et al. | Pharmacokinetics of formulated tenoxicam transdermal delivery systems. | 2008 | J. Pharm. Pharmacol. | pmid:18088513 |
Adachi H et al. | Inhibitory effect of prostaglandin E1 on laurate-induced peripheral vascular occlusive sequelae in rabbits: optimized topical formulation with beta-cyclodextrin derivative and penetration enhancer HPE-101. | 1992 | J. Pharm. Pharmacol. | pmid:1361553 |