lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

Cross Reference

Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Nephrosis, Lipoid D009402 2 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Vascular System Injuries D057772 2 associated lipids
Per page 10 20 50 | Total 33

PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

Download all related citations
Per page 10 20 50 100 | Total 1837
Authors Title Published Journal PubMed Link
Honoré B et al. Cobinding of bilirubin and laurate to human serum albumin: spectroscopic characterization of stoichiometric complexes. 1988 Arch. Biochem. Biophys. pmid:3178221
Shet Ms et al. The omega-hydroxlyation of lauric acid: oxidation of 12-hydroxlauric acid to dodecanedioic acid by a purified recombinant fusion protein containing P450 4A1 and NADPH-P450 reductase. 1996 Arch. Biochem. Biophys. pmid:8651697
Lewis DF Essential requirements for substrate binding affinity and selectivity toward human CYP2 family enzymes. 2003 Arch. Biochem. Biophys. pmid:12464242
Puchkaev AV et al. Aromatic stacking as a determinant of the thermal stability of CYP119 from Sulfolobus solfataricus. 2003 Arch. Biochem. Biophys. pmid:12464244
Rock DA et al. A method for determining two substrates binding in the same active site of cytochrome P450BM3: an explanation of high energy omega product formation. 2003 Arch. Biochem. Biophys. pmid:12859976
Cheesman MJ et al. Rabbit CYP4B1 engineered for high-level expression in Escherichia coli: ligand stabilization and processing of the N-terminus and heme prosthetic group. 2003 Arch. Biochem. Biophys. pmid:12859977
Salaün JP et al. Differential inactivation of plant lauric acid omega- and in-chain-hydroxylases by terminally unsaturated fatty acids. 1988 Arch. Biochem. Biophys. pmid:3341756
Finlayson MJ et al. Differential expression of cytochrome P-450 1 and related forms in rabbit liver and kidney. 1987 Arch. Biochem. Biophys. pmid:3492962
Kahn RA et al. A conservative amino acid substitution alters the regiospecificity of CYP94A2, a fatty acid hydroxylase from the plant Vicia sativa. 2001 Arch. Biochem. Biophys. pmid:11437349
Loughran PA et al. The kinetic and spectral characterization of the E. coli-expressed mammalian CYP4A7: cytochrome b5 effects vary with substrate. 2001 Arch. Biochem. Biophys. pmid:11368012
Norman HA and Thompson GA Effects of low-temperature stress on the metabolism of phosphatidylglycerol molecular species in Dunaliella salina. 1985 Arch. Biochem. Biophys. pmid:4051499
Sharma P et al. Structural basis of the binding of fatty acids to peptidoglycan recognition protein, PGRP-S through second binding site. 2013 Arch. Biochem. Biophys. pmid:23149273
Arkill KP and Winlove CP Fatty acid transport in articular cartilage. 2006 Arch. Biochem. Biophys. pmid:17084376
Miranda CL et al. Purification and characterization of hepatic steroid hydroxylases from untreated rainbow trout. 1989 Arch. Biochem. Biophys. pmid:2536262
Cowart LA et al. Structural determinants of active site binding affinity and metabolism by cytochrome P450 BM-3. 2001 Arch. Biochem. Biophys. pmid:11368173
Duncan T et al. A glycoprotein binding retinoids and fatty acids is present in Drosophila. 1994 Arch. Biochem. Biophys. pmid:8031123
Gilep AA et al. Reconstitution of the enzymatic activities of cytochrome P450s using recombinant flavocytochromes containing rat cytochrome b(5) fused to NADPH--cytochrome P450 reductase with various membrane-binding segments. 2001 Arch. Biochem. Biophys. pmid:11396924
Puchkaev AV and Ortiz de Montellano PR The Sulfolobus solfataricus electron donor partners of thermophilic CYP119: an unusual non-NAD(P)H-dependent cytochrome P450 system. 2005 Arch. Biochem. Biophys. pmid:15629120
Kikuta Y et al. Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14. 2000 Arch. Biochem. Biophys. pmid:11185557
Straub P et al. Hydrophobic side chain requirements for lauric acid and progesterone hydroxylation at amino acid 113 in cytochrome P450 2C2, a potential determinant of substrate specificity. 1993 Arch. Biochem. Biophys. pmid:8215458