MeSH term | MeSH ID | Detail |
---|---|---|
Nephrosis, Lipoid | D009402 | 2 associated lipids |
Carotid Artery Injuries | D020212 | 8 associated lipids |
Vascular System Injuries | D057772 | 2 associated lipids |
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with lauric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Amichot M et al. | Induction of cytochrome P450 activities in Drosophila melanogaster strains susceptible or resistant to insecticides. | 1998 | Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. | pmid:9972473 |
Orellana M et al. | Modulation of peroxisomal and microsomal fatty acid oxidation by acetone. A comparative study between liver and kidney. | 1998 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:9972312 |
Oszi Z and Pethö G | Quantitative determination of polysorbate 20 in nasal pharmaceutical preparations by high-performance liquid chromatography. | 1998 | J Pharm Biomed Anal | pmid:9919973 |
Noble MA et al. | Imidazolyl carboxylic acids as mechanistic probes of flavocytochrome P-450 BM3. | 1998 | Biochemistry | pmid:9843385 |
Lee Y et al. | Preparation of slightly hydrophobic heparin derivatives which can be used for solvent casting in polymeric formulation. | 1998 | Thromb. Res. | pmid:9840023 |
Kroetz DL et al. | Peroxisome proliferator-activated receptor alpha controls the hepatic CYP4A induction adaptive response to starvation and diabetes. | 1998 | J. Biol. Chem. | pmid:9813074 |
Orellana M et al. | Peroxisomal and microsomal fatty acid oxidation in liver of rats after chronic ethanol consumption. | 1998 | Gen. Pharmacol. | pmid:9809485 |
Temme EH et al. | Individual saturated fatty acids and effects on whole blood aggregation in vitro. | 1998 | Eur J Clin Nutr | pmid:9805214 |
Grinberg F et al. | A new formalism for the evaluation of order-fluctuation modes in liquid crystals from field-cycling NMR-relaxometry data. | 1998 | J. Magn. Reson. | pmid:9799675 |
Andersen Borge GI et al. | Fatty acid alpha-oxidation of tetradecylthioacetic acid and tetradecylthiopropionic acid in cucumber (Cucumis sativus). | 1998 | Biochim. Biophys. Acta | pmid:9795197 |
Zimmer T et al. | Mutual conversion of fatty-acid substrate specificity by a single amino-acid exchange at position 527 in P-450Cm2 and P-450Alk3A. | 1998 | Eur. J. Biochem. | pmid:9760180 |
Sawaguchi T and Nishida H | Fatty liver in sudden infant death autopsies. | 1998 | Am J Forensic Med Pathol | pmid:9760100 |
Meyer JH et al. | Length of intestinal contact on nutrient-driven satiety. | 1998 | Am. J. Physiol. | pmid:9756564 |
Zheng YM et al. | Identification of a meander region proline residue critical for heme binding to cytochrome P450: implications for the catalytic function of human CYP4B1. | 1998 | Biochemistry | pmid:9737862 |
Kam W et al. | Contribution of omega-oxidation to fatty acid oxidation by liver of rat and monkey. | 1978 | J. Lipid Res. | pmid:97354 |
Ueda I and Suzuki A | Is there a specific receptor for anesthetics? Contrary effects of alcohols and fatty acids on phase transition and bioluminescence of firefly luciferase. | 1998 | Biophys. J. | pmid:9675206 |
Tappenden KA et al. | Short-chain fatty acid-supplemented total parenteral nutrition alters intestinal structure, glucose transporter 2 (GLUT2) mRNA and protein, and proglucagon mRNA abundance in normal rats. | 1998 | Am. J. Clin. Nutr. | pmid:9665105 |
Macdonald ID et al. | Fatty acid-induced alteration of the porphyrin macrocycle of cytochrome P450 BM3. | 1998 | Biophys. J. | pmid:9635777 |
Samartsev VN et al. | Involvement of aspartate/glutamate antiporter in uncoupling effect of fatty acids in heart mitochondria. | 1998 | Biochemistry Mosc. | pmid:9632895 |
Amet Y et al. | P-450-dependent metabolism of lauric acid in alcoholic liver disease: comparison between rat liver and kidney microsomes. | 1998 | Alcohol. Clin. Exp. Res. | pmid:9581653 |
Guan X et al. | Cytochrome P450-dependent desaturation of lauric acid: isoform selectivity and mechanism of formation of 11-dodecenoic acid. | 1998 | Chem. Biol. Interact. | pmid:9566728 |
Miura Y and Oda S | Oxidation of fatty acids by kidney microsomes of musk shrew (Suncus murinus). | 1998 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:9530812 |
Björkhem I and Kallner A | Hepatic 7alpha-hydroxylation of cholesterol in ascorbate-deficient and ascorbate-supplemented guinea pigs. | 1976 | J. Lipid Res. | pmid:950498 |
Lind KE and Moller JV | Ligand-apomyoglobin interactions. Configurational adaptability of the haem-binding site. | 1976 | Biochem. J. | pmid:949328 |
Lindmark T et al. | Absorption enhancement through intracellular regulation of tight junction permeability by medium chain fatty acids in Caco-2 cells. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9435199 |
Wiberg E et al. | Fatty acid distribution and lipid metabolism in developing seeds of laurate-producing rape (Brassica napus L.). | 1997 | Planta | pmid:9431681 |
Green PR and Geer BW | Changes in the fatty acid composition of Drosophila melanogaster during development and ageing. | 1979 | Arch. Int. Physiol. Biochim. | pmid:93438 |
Poli-Scaife S et al. | The substrate binding site of human liver cytochrome P450 2C9: an NMR study. | 1997 | Biochemistry | pmid:9335524 |
Sigalet DL et al. | Determination of the route of medium-chain and long-chain fatty acid absorption by direct measurement in the rat. | 1997 Sep-Oct | JPEN J Parenter Enteral Nutr | pmid:9323689 |
Westergaard H and Dietschy JM | The mechanism whereby bile acid micelles increase the rate of fatty acid and cholesterol uptake into the intestinal mucosal cell. | 1976 | J. Clin. Invest. | pmid:932213 |
Buhler DR et al. | The regiospecific hydroxylation of lauric acid by rainbow trout (Oncorhynchus mykiss) cytochrome P450s. | 1997 | Drug Metab. Dispos. | pmid:9321521 |
Kakinuma K et al. | Effect of ionic sites of surfactants on leukocyte metabolism. | 1976 | J. Biochem. | pmid:931977 |
Maves SA et al. | Decreased substrate affinity upon alteration of the substrate-docking region in cytochrome P450(BM-3). | 1997 | FEBS Lett. | pmid:9315688 |
Imaoka S et al. | Mutagenic activation of urinary bladder carcinogens by CYP4B1 and the presence of CYP4B1 in bladder mucosa. | 1997 | Biochem. Pharmacol. | pmid:9310344 |
Winkelaar GB et al. | Fat absorption after small intestinal transplantation in the rat. | 1997 | Transplantation | pmid:9293866 |
Sunshine MG et al. | Mutation of the htrB gene in a virulent Salmonella typhimurium strain by intergeneric transduction: strain construction and phenotypic characterization. | 1997 | J. Bacteriol. | pmid:9287009 |
Kroetz DL et al. | Developmentally regulated expression of the CYP4A genes in the spontaneously hypertensive rat kidney. | 1997 | Mol. Pharmacol. | pmid:9281597 |
Djelouah I et al. | Fat embolism in orthopedic surgery: role of bone marrow fatty acid. | 1997 | Anesth. Analg. | pmid:9249128 |
Crespi CL and Miller VP | The R144C change in the CYP2C9*2 allele alters interaction of the cytochrome P450 with NADPH:cytochrome P450 oxidoreductase. | 1997 | Pharmacogenetics | pmid:9241660 |
Murataliev MB et al. | Functional interactions in cytochrome P450BM3: flavin semiquinone intermediates, role of NADP(H), and mechanism of electron transfer by the flavoprotein domain. | 1997 | Biochemistry | pmid:9204888 |
Chevalier G et al. | Distribution study of radioactivity in rats after oral administration of the lipido/sterolic extract of Serenoa repens (Permixon) supplemented with [1-14C]-lauric acid, [1-14C]-oleic acid or [4-14C]-beta-sitosterol. | 1997 Jan-Mar | Eur J Drug Metab Pharmacokinet | pmid:9179563 |
Orellana M et al. | Microsomal and peroxisomal fatty acid oxidation in bile duct ligated rats: a comparative study between liver and kidney. | 1997 | Gen. Pharmacol. | pmid:9147020 |
Amet Y et al. | Cytochrome P450 4A and 2E1 expression in human kidney microsomes. | 1997 | Biochem. Pharmacol. | pmid:9113097 |
Clementz T et al. | Function of the Escherichia coli msbB gene, a multicopy suppressor of htrB knockouts, in the acylation of lipid A. Acylation by MsbB follows laurate incorporation by HtrB. | 1997 | J. Biol. Chem. | pmid:9099672 |
Khosla P et al. | Decreasing dietary lauric and myristic acids improves plasma lipids more favorably than decreasing dietary palmitic acid in rhesus monkeys fed AHA step 1 type diets. | 1997 | J. Nutr. | pmid:9082040 |
Orellana M et al. | Microsomal and peroxisomal fatty acid oxidation in streptozotocin diabetic rat liver. | 1997 | Gen. Pharmacol. | pmid:9068973 |
Kragh-Hansen U et al. | High-affinity binding of laurate to naturally occurring mutants of human serum albumin and proalbumin. | 1996 | Biochem. J. | pmid:9003380 |
Helvig C et al. | Suicide inactivation of cytochrome P450 by midchain and terminal acetylenes. A mechanistic study of inactivation of a plant lauric acid omega-hydroxylase. | 1997 | J. Biol. Chem. | pmid:8995277 |
Winkler E et al. | Identification of the pH sensor for nucleotide binding in the uncoupling protein from brown adipose tissue. | 1997 | Biochemistry | pmid:8993328 |
Lu P et al. | Heme-coordinating analogs of lauric acid as inhibitors of fatty acid omega-hydroxylation. | 1997 | Arch. Biochem. Biophys. | pmid:8990261 |