lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

Cross Reference

Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Nephrosis, Lipoid D009402 2 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Vascular System Injuries D057772 2 associated lipids
Per page 10 20 50 | Total 33

PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

Download all related citations
Per page 10 20 50 100 | Total 1837
Authors Title Published Journal PubMed Link
Mo S et al. Elucidation of the Streptomyces coelicolor pathway to 2-undecylpyrrole, a key intermediate in undecylprodiginine and streptorubin B biosynthesis. 2008 Chem. Biol. pmid:18291318
Marynka K et al. In vitro discriminative antipseudomonal properties resulting from acyl substitution of N-terminal sequence of dermaseptin s4 derivatives. 2007 Chem. Biol. pmid:17254954
Sun CQ et al. The antimicrobial properties of milkfat after partial hydrolysis by calf pregastric lipase. 2002 Chem. Biol. Interact. pmid:12076524
Bacher MA and Gibson GG Chlorophenoxyacid herbicides induce microsomal cytochrome P-450 IVA1 (P-452) in rat liver. 1988 Chem. Biol. Interact. pmid:3365825
Charest-Boule L et al. Influence of free fatty acid anion on the binding of warfarin to cytoplasmic proteins from rat liver. 1980 Chem. Biol. Interact. pmid:7356538
Weinkam RJ et al. Protein mediated chemical reactions of chloroethylnitrosoureas. 1980 Chem. Biol. Interact. pmid:7389008
Guan X et al. Cytochrome P450-dependent desaturation of lauric acid: isoform selectivity and mechanism of formation of 11-dodecenoic acid. 1998 Chem. Biol. Interact. pmid:9566728
Staab CA et al. Medium-chain fatty acids and glutathione derivatives as inhibitors of S-nitrosoglutathione reduction mediated by alcohol dehydrogenase 3. 2009 Chem. Biol. Interact. pmid:19428350
Tran NH et al. Light-initiated hydroxylation of lauric acid using hybrid P450 BM3 enzymes. 2011 Chem. Commun. (Camb.) pmid:21975564
Weissenborn MJ et al. Whole-cell microtiter plate screening assay for terminal hydroxylation of fatty acids by P450s. 2016 Chem. Commun. (Camb.) pmid:27074906
Ribot F et al. In situ evaluation of interfacial affinity in CeO2 based hybrid nanoparticles by pulsed field gradient NMR. 2005 Chem. Commun. (Camb.) pmid:15719102
Uchida T et al. Preparation and characterization of insulin-loaded acrylic hydrogels containing absorption enhancers. 2001 Chem. Pharm. Bull. pmid:11605651
de Regil-Hernández R et al. New green synthesis and formulations of acyclovir prodrugs. 2011 Chem. Pharm. Bull. pmid:21881250
Liu CH and Huang HY In vitro anti-propionibacterium activity by curcumin containing vesicle system. 2013 Chem. Pharm. Bull. pmid:23546001
Kamachi S et al. Spectrophotometric assay for lipase in serum using a chromogenic substrate, Orange I laurate. 1983 Chem. Pharm. Bull. pmid:6652817
Ogiso T et al. Enhancement effect of lauric acid on the rectal absorption of propranolol from suppository in rats. 1991 Chem. Pharm. Bull. pmid:1806286
Watanabe T et al. Co-suppression by nicardipine, a calcium antagonist, of induction of microsomal lauric acid hydroxylation with peroxisome proliferation in clofibrate-treated rat liver. 1991 Chem. Pharm. Bull. pmid:1914008
Iwahashi M et al. Dynamical dimer structure and liquid structure of fatty acids in their binary liquid mixture: dodecanoic and 3-phenylpropionic acids system. 2004 Chem. Phys. Lipids pmid:15081860
Inoue T et al. Solid-liquid phase behavior of binary fatty acid mixtures. 2. Mixtures of oleic acid with lauric acid, myristic acid, and palmitic acid. 2004 Chem. Phys. Lipids pmid:14725999
Fauconnot L et al. Chemical synthesis and NMR characterization of structured polyunsaturated triacylglycerols. 2006 Chem. Phys. Lipids pmid:16405879
Costa MC et al. The solid-liquid phase diagrams of binary mixtures of consecutive, even saturated fatty acids. 2009 Chem. Phys. Lipids pmid:19520067
Chaleepa K et al. Effect of additives on isothermal crystallization kinetics and physical characteristics of coconut oil. 2010 Chem. Phys. Lipids pmid:20346930
Mirsky VM Effect of the lipid hydrolysis products on the phospholipase A2 action towards lipid monolayer. 1994 Chem. Phys. Lipids pmid:8013058
Iwahashi M et al. Dynamical dimer structure and liquid structure of fatty acids in their binary liquid mixture: decanoic/octadecanoic acid and decanoic/dodecanoic acid systems. 2005 Chem. Phys. Lipids pmid:15642581
Grillo MP and Hua F Enantioselective formation of ibuprofen-S-acyl-glutathione in vitro in incubations of ibuprofen with rat hepatocytes. 2008 Chem. Res. Toxicol. pmid:18680316
Clarke SE et al. Lauric acid as a model substrate for the simultaneous determination of cytochrome P450 2E1 and 4A in hepatic microsomes. 1994 Nov-Dec Chem. Res. Toxicol. pmid:7696540
Barham P et al. Molecular gastronomy: a new emerging scientific discipline. 2010 Chem. Rev. pmid:20170128
Mattes RD Oral thresholds and suprathreshold intensity ratings for free fatty acids on 3 tongue sites in humans: implications for transduction mechanisms. 2009 Chem. Senses pmid:19357229
Su Z et al. Rates of fatty acid oxidations by P450 compound I are pH dependent. 2012 Chembiochem pmid:22890798
Wu B et al. Broad hexagonal columnar mesophases formation in bioinspired transition-metal complexes of simple fatty acid meta-octaester derivatives of meso-tetraphenyl porphyrins. 2015 Chemistry pmid:25619819
Si S et al. In situ synthesis of gold and silver nanoparticles by using redox-active amphiphiles and their phase transfer to organic solvents. 2007 Chemistry pmid:17960550
Coll C et al. Fatty acid carboxylate- and anionic surfactant-controlled delivery systems that use mesoporous silica supports. 2010 Chemistry pmid:20645326
Fauser JK et al. Induction of apoptosis by the medium-chain length fatty acid lauric acid in colon cancer cells due to induction of oxidative stress. 2013 Chemotherapy pmid:24356281
Fu J et al. Hydrothermal decarboxylation and hydrogenation of fatty acids over Pt/C. 2011 ChemSusChem pmid:21275064
Chen Y et al. [A new rat model of cerebral infarction based on the injury of vascular endothelial cell]. 2005 Chin J Integr Med pmid:16181534
Scholl J Traditional dietary recommendations for the prevention of cardiovascular disease: do they meet the needs of our patients? 2012 Cholesterol pmid:22482040
Jiang M et al. Smooth muscle--specific expression of CYP4A1 induces endothelial sprouting in renal arterial microvessels. 2004 Circ. Res. pmid:14670847
Fleming I Cytochrome P-450 under pressure: more evidence for a link between 20-hydroxyeicosatetraenoic acid and hypertension. 2005 Circulation pmid:15630035
Gainer JV et al. Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension. 2005 Circulation pmid:15611369
Reginster JY et al. Estradiol pharmacokinetics after transdermal application of patches to postmenopausal women: matrix versus reservoir patches. 2000 Climacteric pmid:11910618
Payne CM et al. Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis. 2011 Clin Exp Gastroenterol pmid:21753893
Jicha GA and Markesbery WR Omega-3 fatty acids: potential role in the management of early Alzheimer's disease. 2010 Clin Interv Aging pmid:20396634
Chan J et al. Effect of water-in-oil microemulsions and lamellar liquid crystalline systems on the precorneal tear film of albino New Zealand rabbits. 2008 Clin Ophthalmol pmid:19668396
Campagnoli M et al. Structural analysis, fatty acid and thyroxine binding properties of Vancouver and Naskapi variants of human serum albumin. 2003 Clin. Biochem. pmid:14636873
Poudrier J et al. Influence of dendritic cells on B-cell responses during HIV infection. 2012 Clin. Dev. Immunol. pmid:22461837
Pandey SK et al. A tribute to Charles David Kelman MD: ophthalmologist, inventor and pioneer of phacoemulsification surgery. 2004 Clin. Experiment. Ophthalmol. pmid:15498067
Haim A et al. Patellofemoral pain syndrome: validity of clinical and radiological features. 2006 Clin. Orthop. Relat. Res. pmid:16788411
Edirisinghe I et al. Effect of fatty acids on endothelium-dependent relaxation in the rabbit aorta. 2006 Clin. Sci. pmid:16524362
Marie SK and Shinjo SM Metabolism and brain cancer. 2011 Clinics (Sao Paulo) pmid:21779721
Kim YJ et al. Combination of nanoparticles with photothermal effects and phase-change material enhances the non-invasive transdermal delivery of drugs. 2015 Colloids Surf B Biointerfaces pmid:26277712