lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

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Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Nephrosis, Lipoid D009402 2 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Vascular System Injuries D057772 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

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What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

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Authors Title Published Journal PubMed Link
Honoré B et al. Cobinding of bilirubin and laurate to human serum albumin: spectroscopic characterization of stoichiometric complexes. 1988 Arch. Biochem. Biophys. pmid:3178221
Rock DA et al. A method for determining two substrates binding in the same active site of cytochrome P450BM3: an explanation of high energy omega product formation. 2003 Arch. Biochem. Biophys. pmid:12859976
Cheesman MJ et al. Rabbit CYP4B1 engineered for high-level expression in Escherichia coli: ligand stabilization and processing of the N-terminus and heme prosthetic group. 2003 Arch. Biochem. Biophys. pmid:12859977
Hoch U et al. Structural determination of the substrate specificities and regioselectivities of the rat and human fatty acid omega-hydroxylases. 2000 Arch. Biochem. Biophys. pmid:10620324
Williams DE et al. Regiospecific hydroxylation of lauric acid at the (omega-1) position by hepatic and kidney microsomal cytochromes P-450 from rainbow trout. 1984 Arch. Biochem. Biophys. pmid:6732245
Kawashima H et al. Human fatty acid omega-hydroxylase, CYP4A11: determination of complete genomic sequence and characterization of purified recombinant protein. 2000 Arch. Biochem. Biophys. pmid:10860550
Wang MH et al. Cloning, sequencing, and cDNA-directed expression of the rat renal CYP4A2: arachidonic acid omega-hydroxylation and 11,12-epoxidation by CYP4A2 protein. 1996 Arch. Biochem. Biophys. pmid:8954571
Miranda CL et al. Purification and characterization of hepatic steroid hydroxylases from untreated rainbow trout. 1989 Arch. Biochem. Biophys. pmid:2536262
Jeffery B et al. Peroxisome proliferator activated receptor alpha regulates a male-specific cytochrome P450 in mouse liver. 2004 Arch. Biochem. Biophys. pmid:15313227
Chavez JA and Summers SA Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes. 2003 Arch. Biochem. Biophys. pmid:14592453