| MeSH term | MeSH ID | Detail |
|---|---|---|
| Nephrosis, Lipoid | D009402 | 2 associated lipids |
| Carotid Artery Injuries | D020212 | 8 associated lipids |
| Vascular System Injuries | D057772 | 2 associated lipids |
lauric acid
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
Cross Reference
Introduction
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with lauric acid?
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with lauric acid
PubChem Associated disorders and diseases
What pathways are associated with lauric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with lauric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with lauric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with lauric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with lauric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with lauric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with lauric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Viswanathan TS and Cushley RJ | Deuterium nuclear magnetic resonance study of the interaction of substrates and inhibitors with soybean lipoxygenase. | 1981 | J. Biol. Chem. | pmid:6788761 |
| Lee JY et al. | Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids. | 2003 | J. Biol. Chem. | pmid:12865424 |
| Vottero E et al. | Role of residue 87 in substrate selectivity and regioselectivity of drug-metabolizing cytochrome P450 CYP102A1 M11. | 2011 | J. Biol. Inorg. Chem. | pmid:21567268 |
| Chen CK et al. | The effect of mutation of F87 on the properties of CYP102A1-CYP4C7 chimeras: altered regiospecificity and substrate selectivity. | 2008 | J. Biol. Inorg. Chem. | pmid:18392864 |
| Darvishi F et al. | Effect of plant oils upon lipase and citric acid production in Yarrowia lipolytica yeast. | 2009 | J. Biomed. Biotechnol. | pmid:19826636 |
| Man D et al. | Effect of chlorotriphenyl derivatives of Sn and Pb upon biophysical properties of membranes. | 2009 | J. Biomed. Biotechnol. | pmid:19606258 |
| Laurin D et al. | Exploration of the lysis mechanisms of leukaemic blasts by chimaeric T-cells. | 2010 | J. Biomed. Biotechnol. | pmid:20617141 |
| Pradhan P et al. | Comparative evaluation of heating ability and biocompatibility of different ferrite-based magnetic fluids for hyperthermia application. | 2007 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:16924619 |
| Crépy L et al. | Evaluation of a bio-based hydrophobic cellulose laurate film as biomaterial--study on biodegradation and cytocompatibility. | 2012 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:22323390 |
| Ramesh KV et al. | Modeling the interactions of herbal drugs to beta-ketoacyl ACP synthase of Mycobacterium tuberculosis H37Rv. | 2008 | J. Biomol. Struct. Dyn. | pmid:18282003 |
| Maity K et al. | Insights into the substrate specificity of a thioesterase Rv0098 of mycobacterium tuberculosis through X-ray crystallographic and molecular dynamics studies. | 2012 | J. Biomol. Struct. Dyn. | pmid:22292955 |
| Yamazaki E et al. | Kinetics of fatty acid binding ability of glycated human serum albumin. | 2005 | J. Biosci. | pmid:16184009 |
| Hirata Y et al. | Novel characteristics of sophorolipids, yeast glycolipid biosurfactants, as biodegradable low-foaming surfactants. | 2009 | J. Biosci. Bioeng. | pmid:19619862 |
| Islam NN et al. | Synthesis and degradation of acyl peptide using enzyme from Pseudomonas aeruginosa. | 2008 | J. Biosci. Bioeng. | pmid:18397780 |
| Maeda A et al. | Characterization of novel cholesterol esterase from Trichoderma sp. AS59 with high ability to synthesize steryl esters. | 2008 | J. Biosci. Bioeng. | pmid:18499049 |
| Okamoto K et al. | Production of gamma-lactones by the brown-rot basidiomycete Piptoporus soloniensis. | 2002 | J. Biosci. Bioeng. | pmid:16233291 |
| Wang Q and Nomura CT | Monitoring differences in gene expression levels and polyhydroxyalkanoate (PHA) production in Pseudomonas putida KT2440 grown on different carbon sources. | 2010 | J. Biosci. Bioeng. | pmid:20807680 |
| Matsumoto K et al. | Biosynthesis of glycolate-based polyesters containing medium-chain-length 3-hydroxyalkanoates in recombinant Escherichia coli expressing engineered polyhydroxyalkanoate synthase. | 2011 | J. Biotechnol. | pmid:21907740 |
| Dietrich M et al. | Altering the regioselectivity of the subterminal fatty acid hydroxylase P450 BM-3 towards gamma- and delta-positions. | 2009 | J. Biotechnol. | pmid:18984016 |
| Koreishi M et al. | Efficient Nepsilon-lauroyl-L-lysine production by recombinant epsilon-lysine acylase from Streptomyces mobaraensis. | 2009 | J. Biotechnol. | pmid:19433221 |
| Hu QZ and Jang CH | Using liquid crystals for the label-free detection of catalase at aqueous-LC interfaces. | 2012 | J. Biotechnol. | pmid:22138010 |
| Topakas E et al. | Comparison of mesophilic and thermophilic feruloyl esterases: characterization of their substrate specificity for methyl phenylalkanoates. | 2005 | J. Biotechnol. | pmid:15639097 |
| Schulz CM et al. | Identification of new homoterpene esters from Dufour's gland of the ponerine ant Gnamptogenys striatula. | 2002 | J. Chem. Ecol. | pmid:12564799 |
| Blatrix R et al. | Trail pheromone of ponerine ant Gnamptogenys striatula: 4-methylgeranyl esters from Dufour's gland. | 2002 | J. Chem. Ecol. | pmid:12564800 |
| Smallegange RC et al. | The effect of aliphatic carboxylic acids on olfaction-based host-seeking of the malaria mosquito Anopheles gambiae sensu stricto. | 2009 | J. Chem. Ecol. | pmid:19626371 |
| Dirven HA et al. | Determination of the cytochrome P-450 IV marker, omega-hydroxylauric acid, by high-performance liquid chromatography and fluorimetric detection. | 1991 | J. Chromatogr. | pmid:1860919 |
| Maurich V et al. | p-nitrophenyllaurate: a substrate for the high-performance liquid chromatographic determination of lipase activity. | 1991 | J. Chromatogr. | pmid:1939456 |
| Amet Y et al. | Simultaneous radiometric and fluorimetric detection of lauric acid metabolites using high-performance liquid chromatography following esterification with 4-bromomethyl-6,7-dimethoxycoumarin in human and rat liver microsomes. | 1996 | J. Chromatogr. B, Biomed. Appl. | pmid:8811432 |
| Saito M et al. | 2-(5-hydrazinocarbonyl-2-oxazolyl)-5,6-dimethoxybenzothiazole as a precolumn fluorescence derivatization reagent for carboxylic acids in high-performance liquid chromatography and its application to the assay of fatty acids in human serum. | 1995 | J. Chromatogr. B, Biomed. Appl. | pmid:8788145 |
| The Endocrine Society 2012 Laureate Awards. | 2012 | J. Clin. Endocrinol. Metab. | pmid:22869853 | |
| Chopra IJ et al. | A competitive ligand binding assay for measurement of thyroid hormone-binding inhibitor in serum and tissues. | 1984 | J. Clin. Endocrinol. Metab. | pmid:6421865 |
| Westergaard H and Dietschy JM | The mechanism whereby bile acid micelles increase the rate of fatty acid and cholesterol uptake into the intestinal mucosal cell. | 1976 | J. Clin. Invest. | pmid:932213 |
| Kinderlerer JL et al. | Effect of medium-chain fatty acids in mould ripened cheese on the growth of Listeria monocytogenes. | 1996 | J. Dairy Res. | pmid:8933308 |
| Giesy JG et al. | Effect of dose of calcium salts of conjugated linoleic acid (CLA) on percentage and fatty acid content of milk fat in midlactation holstein cows. | 2002 | J. Dairy Sci. | pmid:12214995 |
| Li L and Ma Y | Effect of fatty acids on the β-oxidation system and thioesterase of Lactococcus lactis subspecies lactis. | 2013 | J. Dairy Sci. | pmid:23462166 |
| Nafikov RA et al. | Sterol regulatory element binding transcription factor 1 (SREBF1) polymorphism and milk fatty acid composition. | 2013 | J. Dairy Sci. | pmid:23403193 |
| Faciola AP and Broderick GA | Effects of feeding lauric acid or coconut oil on ruminal protozoa numbers, fermentation pattern, digestion, omasal nutrient flow, and milk production in dairy cows. | 2014 | J. Dairy Sci. | pmid:24931520 |
| Hristov AN et al. | Effect of sodium laurate on ruminal fermentation and utilization of ruminal ammonia nitrogen for milk protein synthesis in dairy cows. | 2004 | J. Dairy Sci. | pmid:15453498 |
| van Zijderveld SM et al. | Effects of a combination of feed additives on methane production, diet digestibility, and animal performance in lactating dairy cows. | 2011 | J. Dairy Sci. | pmid:21338809 |
| Hristov AN et al. | Effects of lauric and myristic acids on ruminal fermentation, production, and milk fatty acid composition in lactating dairy cows. | 2011 | J. Dairy Sci. | pmid:21183049 |
| Hristov AN et al. | Effect of lauric acid and coconut oil on ruminal fermentation, digestion, ammonia losses from manure, and milk fatty acid composition in lactating cows. | 2009 | J. Dairy Sci. | pmid:19841218 |
| Hermansen JE | Prediction of milk fatty acid profile in dairy cows fed dietary fat differing in fatty acid composition. | 1995 | J. Dairy Sci. | pmid:7790578 |
| Rindsig RB and Schultz LH | Effect of feeding lauric acid to lactating cows on milk composition, rumen fermentation, and blood lipids. | 1974 | J. Dairy Sci. | pmid:4430768 |
| Mills JK et al. | The effects of feeding medium-chain triglycerides on the growth, insulin responsiveness, and body composition of Holstein calves from birth to 85 kg of body weight. | 2010 | J. Dairy Sci. | pmid:20723699 |
| Iwami Y et al. | Effect of sucrose monolaurate on acid production, levels of glycolytic intermediates, and enzyme activities of Streptococcus mutans NCTC 10449. | 1995 | J. Dent. Res. | pmid:7560425 |
| Huang WC et al. | Anti-bacterial and anti-inflammatory properties of capric acid against Propionibacterium acnes: a comparative study with lauric acid. | 2014 | J. Dermatol. Sci. | pmid:24284257 |
| Keegan FP and Blum JJ | Incorporation of label from acetate and laurate into the mannan of Leishmania donovani via the glyoxylate cycle. | 1993 Nov-Dec | J. Eukaryot. Microbiol. | pmid:7904877 |
| Collar DC et al. | Habitat use affects morphological diversification in dragon lizards. | 2010 | J. Evol. Biol. | pmid:20345808 |
| López-Villalobos A et al. | Changes in fatty acid composition during development of tissues of coconut (Cocos nucifera L.) embryos in the intact nut and in vitro. | 2001 | J. Exp. Bot. | pmid:11432910 |
| Zhou Z et al. | BnMs3 is required for tapetal differentiation and degradation, microspore separation, and pollen-wall biosynthesis in Brassica napus. | 2012 | J. Exp. Bot. | pmid:22174440 |
| Dong L et al. | Lauric acid in crown daisy root exudate potently regulates root-knot nematode chemotaxis and disrupts Mi-flp-18 expression to block infection. | 2014 | J. Exp. Bot. | pmid:24170741 |
| Thompson EP et al. | An Arabidopsis flavonoid transporter is required for anther dehiscence and pollen development. | 2010 | J. Exp. Bot. | pmid:19995827 |
| Höfer R et al. | The Arabidopsis cytochrome P450 CYP86A1 encodes a fatty acid omega-hydroxylase involved in suberin monomer biosynthesis. | 2008 | J. Exp. Bot. | pmid:18544608 |
| Hinton A and Ingram KD | Antimicrobial activity of potassium hydroxide and lauric acid against microorganisms associated with poultry processing. | 2006 | J. Food Prot. | pmid:16865894 |
| Hinton A and Cason JA | Bacterial flora of processed broiler chicken skin after successive washings in mixtures of potassium hydroxide and lauric acid. | 2008 | J. Food Prot. | pmid:18724769 |
| Hinton A and Ingram KD | Microbicidal activity of tripotassium phosphate and fatty acids toward spoilage and pathogenic bacteria associated with poultry. | 2005 | J. Food Prot. | pmid:16013388 |
| Hoffman KL et al. | Antimicrobial effects of corn zein films impregnated with nisin, lauric acid, and EDTA. | 2001 | J. Food Prot. | pmid:11403145 |
| Fu J et al. | Camphor Tree Seed Kernel Oil Reduces Body Fat Deposition and Improves Blood Lipids in Rats. | 2015 | J. Food Sci. | pmid:26130050 |
| Nehdi IA et al. | Chamaerops humilis L. var. argentea André date palm seed oil: a potential dietetic plant product. | 2014 | J. Food Sci. | pmid:24666023 |
| Lungu B et al. | Resistance of nutrient-deprived Listeria monocytogenes 10403S and a DeltasigB mutant to chemical stresses in the presence or absence of oxygen. | 2008 | J. Food Sci. | pmid:18803717 |
| Martin EM et al. | Control of Listeria monocytogenes by lauric arginate on frankfurters formulated with or without lactate/diacetate. | 2009 | J. Food Sci. | pmid:19723207 |
| Marthina K and Barringer SA | Confectionery coating with an electrohydrodynamic (EHD) system. | 2012 | J. Food Sci. | pmid:22181825 |
| Hagens S | Potential misuse of an antimicrobial resulting from a miscalculation in an efficacy study. | 2010 Jan-Feb | J. Food Sci. | pmid:20492212 |
| Jacques NA | Membrane perturbation by cerulenin modulates glucosyltransferase secretion and acetate uptake by Streptococcus salivarius. | 1983 | J. Gen. Microbiol. | pmid:6229601 |
| Hornung B et al. | Lauric acid inhibits the maturation of vesicular stomatitis virus. | 1994 | J. Gen. Virol. | pmid:8113756 |
| Yuan Y et al. | Coupling electrokinetics with microbial biodegradation enhances the removal of cycloparaffinic hydrocarbons in soils. | 2016 | J. Hazard. Mater. | pmid:27501882 |
| Cho BH et al. | Highly polymorphic human CYP4A11 gene. | 2005 | J. Hum. Genet. | pmid:15895287 |
| Weatherill AR et al. | Saturated and polyunsaturated fatty acids reciprocally modulate dendritic cell functions mediated through TLR4. | 2005 | J. Immunol. | pmid:15843537 |
| Asai Y et al. | Soluble CD14 discriminates slight structural differences between lipid as that lead to distinct host cell activation. | 2007 | J. Immunol. | pmid:18025213 |
| Dailey MO et al. | Induction of cell-mediated immunity to chemically modified antigens in guinea pigs. II. The interaction between lipid-conjugated antigens, macrophages, and T lymphocytes. | 1977 | J. Immunol. | pmid:300393 |
| Champlin R and Hunter RL | Studies on the composition of adjuvants which selectively enhance delayed-type hypersensitivity to lipid conjugated protein antigens. | 1975 | J. Immunol. | pmid:1089714 |
| Coon J and Hunter R | Properties of conjugated protein immunogens which selectively stimulate delayed-type hypersensitivity. | 1975 | J. Immunol. | pmid:1123546 |
| Dailey MO and Hunter RL | Induction of cell-mediated immunity to chemically modified antigens in guinea pigs. I. Characterization of the immune response to lipid-conjugated protein antigens. | 1977 | J. Immunol. | pmid:66275 |
| Youngquist JT et al. | Functional genomics analysis of free fatty acid production under continuous phosphate limiting conditions. | 2017 | J. Ind. Microbiol. Biotechnol. | pmid:27738839 |
| Hu F and You S | Inactivation of type I polyhydroxyalkanoate synthase in Aeromonas hydrophila resulted in discovery of another potential PHA synthase. | 2007 | J. Ind. Microbiol. Biotechnol. | pmid:17043804 |
| Stanislawski L et al. | Hybridoma antibodies to the lipid-binding site(s) in the amino-terminal region of fibronectin inhibits binding of streptococcal lipoteichoic acid. | 1987 | J. Infect. Dis. | pmid:3298457 |
| Tran NH et al. | A series of hybrid P450 BM3 enzymes with different catalytic activity in the light-initiated hydroxylation of lauric acid. | 2012 | J. Inorg. Biochem. | pmid:22922311 |
| Udit AK et al. | Cobaltocene-mediated catalytic monooxygenation using holo and heme domain cytochrome P450 BM3. | 2004 | J. Inorg. Biochem. | pmid:15337607 |
| Dinan L et al. | Synthesis and biological activities of turkesterone 11alpha-acyl derivatives. | 2003 | J. Insect Sci. | pmid:15841223 |
| van der Valk PG et al. | Skin irritancy of surfactants as assessed by water vapor loss measurements. | 1984 | J. Invest. Dermatol. | pmid:6699429 |
| BLANK IH and GOULD E | Penetration of anionic surfactants into skin. III. Penetration from buffered sodium laurate solutions. | 1961 | J. Invest. Dermatol. | pmid:13869837 |
| BLANK IH and GOULD E | Penetration of anionic surfactants (surface active agents) into skin. I. Penetration of sodium laurate and sodium dodecyl sulfate into excised human skin. | 1959 | J. Invest. Dermatol. | pmid:13801318 |
| Gallo RL and Nakatsuji T | Microbial symbiosis with the innate immune defense system of the skin. | 2011 | J. Invest. Dermatol. | pmid:21697881 |
| Nakatsuji T et al. | Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris. | 2009 | J. Invest. Dermatol. | pmid:19387482 |
| Nakatsuji T et al. | Sebum free fatty acids enhance the innate immune defense of human sebocytes by upregulating beta-defensin-2 expression. | 2010 | J. Invest. Dermatol. | pmid:20032992 |
| Dorset DL | Cholesteryl esters of saturated fatty acids: cosolubility and fractionation of binary mixtures. | 1987 | J. Lipid Res. | pmid:3668393 |
| Huang S et al. | Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways. | 2012 | J. Lipid Res. | pmid:22766885 |
| Lee JY et al. | Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids. | 2003 | J. Lipid Res. | pmid:12562875 |
| Tholstrup T et al. | Effect of fats high in individual saturated fatty acids on plasma lipoprotein[a] levels in young healthy men. | 1995 | J. Lipid Res. | pmid:7595068 |
| Lapidot Y et al. | Use of esters of N-hydroxysuccinimide in the synthesis of N-acylamino acids. | 1967 | J. Lipid Res. | pmid:14564721 |
| Weber N | Metabolism of orally administered rac-1-O-[1'-14C]dodecylglycerol and nutritional effects of dietary rac-1-O-dodecylglycerol in mice. | 1985 | J. Lipid Res. | pmid:4086944 |
| van Wijk GM et al. | Antiviral nucleoside diphosphate diglycerides: improved synthesis and facilitated purification. | 1992 | J. Lipid Res. | pmid:1331283 |
| Dowd SR and Little JM | Preparation of laurylsarcosyltaurine: a surface active constituent of crab gastric juice. | 1976 | J. Lipid Res. | pmid:1270930 |
| Björkhem I and Kallner A | Hepatic 7alpha-hydroxylation of cholesterol in ascorbate-deficient and ascorbate-supplemented guinea pigs. | 1976 | J. Lipid Res. | pmid:950498 |
| Aoyama T et al. | Clofibrate-inducible rat hepatic P450s IVA1 and IVA3 catalyze the omega- and (omega-1)-hydroxylation of fatty acids and the omega-hydroxylation of prostaglandins E1 and F2 alpha. | 1990 | J. Lipid Res. | pmid:2280187 |
| Abdel-Fattah G et al. | Regulation of guinea pig very low density lipoprotein secretion rates by dietary fat saturation. | 1995 | J. Lipid Res. | pmid:7665997 |
| Kam W et al. | Contribution of omega-oxidation to fatty acid oxidation by liver of rat and monkey. | 1978 | J. Lipid Res. | pmid:97354 |
| Spector AA et al. | Quantitative analysis of uptake of free fatty acid by mammalian cells: lauric acid and human erythrocytes. | 1972 | J. Lipid Res. | pmid:5041270 |
| Grinberg F et al. | A new formalism for the evaluation of order-fluctuation modes in liquid crystals from field-cycling NMR-relaxometry data. | 1998 | J. Magn. Reson. | pmid:9799675 |
| Fabiano A et al. | Metabolomic analysis of bronchoalveolar lavage fluid in preterm infants complicated by respiratory distress syndrome: preliminary results. | 2011 | J. Matern. Fetal. Neonatal. Med. | pmid:21781003 |