MeSH term | MeSH ID | Detail |
---|---|---|
Nephrosis, Lipoid | D009402 | 2 associated lipids |
Carotid Artery Injuries | D020212 | 8 associated lipids |
Vascular System Injuries | D057772 | 2 associated lipids |
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with lauric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kusunose E et al. | Effect of cytochrome b5 on fatty acid omega- and (omega-1)-hydroxylation catalyzed by partially purified cytochrome P-450 from rabbit kidney cortex microsomes. | 1981 | J. Biochem. | pmid:7309711 |
Ushijima T et al. | Selective and differential media for isolation and tentative identification of each species of Pityrosporum residing on normal or diseased human skin. | 1981 | Microbiol. Immunol. | pmid:7329340 |
Traul KA et al. | Two-stage carcinogenesis in vitro: transformation of 3-methylcholanthrene-initiated Rauscher murine leukemia virus-infected rat embryo cells by diverse tumor promoters. | 1981 | J. Natl. Cancer Inst. | pmid:6256572 |
Benveniste I et al. | Cytochrome P-450-Dependent omega-Hydroxylation of Lauric Acid by Microsomes from Pea Seedlings. | 1982 | Plant Physiol. | pmid:16662431 |
Gibson WT | Changes in epidermal acid phosphatase levels in response to chemical irritation. | 1982 | Br. J. Dermatol. | pmid:7066188 |
Gibson GG et al. | Cytochrome P-450 induction by clofibrate. Purification and properties of a hepatic cytochrome P-450 relatively specific for the 12- and 11-hydroxylation of dodecanoic acid (lauric acid). | 1982 | Biochem. J. | pmid:7103935 |
Past MR and Cook DE | Effect of diabetes on rat liver cytochrome P-450. Evidence for a unique diabetes-dependent rat liver cytochrome P-450. | 1982 | Biochem. Pharmacol. | pmid:7150359 |
Qureshi N et al. | Purification and structural determination of nontoxic lipid A obtained from the lipopolysaccharide of Salmonella typhimurium. | 1982 | J. Biol. Chem. | pmid:6749846 |
Miura Y | Effect of inhibitors on omega- and (omega-1)-hydroxylation of lauric acid by frog liver microsomes. | 1982 | Lipids | pmid:6984479 |
Dell HD et al. | Etofenamate fatty acid asters. An example of a new route of drug metabolism. | 1982 Jan-Feb | Drug Metab. Dispos. | pmid:6124384 |
Orton TC and Parker GL | The effect of hypolipidemic agents on the hepatic microsomal drug-metabolizing enzyme system of the rat. Induction of cytochrome(s) P-450 with specificity toward terminal hydroxylation of lauric acid. | 1982 Mar-Apr | Drug Metab. Dispos. | pmid:6124394 |
Albers-Jackson B et al. | Incorporation of 14C acetate into the phospholipids and fatty acids of rabbit lens in organ culture. | 1982-1983 | Curr. Eye Res. | pmid:7184702 |
Wollenweber HW et al. | Fatty acid in lipopolysaccharides of Salmonella species grown at low temperature. Identification and position. | 1983 | Eur. J. Biochem. | pmid:6825685 |
Waldeland H and Frenkel JK | Live and killed vaccines against toxoplasmosis in mice. | 1983 | J. Parasitol. | pmid:6827446 |
Jacobsen J and Brodersen R | Albumin-bilirubin binding mechanism. | 1983 | J. Biol. Chem. | pmid:6853485 |
Bogardus JB | Liquid crystal solubilization of cholesterol: potential method for gallstone dissolution. | 1983 | J Pharm Sci | pmid:6864466 |
Lake BG et al. | Induction of lauric acid hydroxylation and maintenance of cytochrome P-450 content by clofibrate in primary cultures of rat hepatocytes. | 1983 | Life Sci. | pmid:6865658 |
Fink AS et al. | Regionally perfused fatty acids augment acid-induced canine pancreatic secretion. | 1983 | Am. J. Physiol. | pmid:6869548 |
Berschauer F et al. | [Nutritive physiological effect of dietary fats in growing swine rations. 3. Effect of sunflower and coconut kernels on protein and fat retention, backfat fatty acid pattern and various blood parameters in piglets]. | 1983 | Arch Tierernahr | pmid:6370196 |
Siess MH et al. | [The effect of cholesterol and the nature of dietary fatty acids on the activities of some microsomal monooxygenases in the rat liver]. | 1983 | Reprod Nutr Dev | pmid:6405460 |
Fink AS et al. | Pancreatic polypeptide release by intraluminal fatty acids. | 1983 | Metab. Clin. Exp. | pmid:6621364 |
Takabayashi K et al. | Coupling between fatty acid binding and sulfhydryl oxidation in bovine serum albumin. | 1983 | Eur. J. Biochem. | pmid:6628382 |
Gibson WT and Teall MR | Interactions of C12 surfactants with the skin: studies on enzyme release and percutaneous absorption in vitro. | 1983 | Food Chem. Toxicol. | pmid:6686185 |
Kimura RE et al. | Decreased oxidative metabolism in neonatal rat lung exposed to hyperoxia. | 1983 | J Appl Physiol Respir Environ Exerc Physiol | pmid:6643186 |
Hasumura S et al. | Effects of starvation on microsomal cytochrome P-450 and laurate-omega-hydroxylation of rat kidney and liver. | 1983 | Jpn. J. Pharmacol. | pmid:6645119 |
Kamachi S et al. | Spectrophotometric assay for lipase in serum using a chromogenic substrate, Orange I laurate. | 1983 | Chem. Pharm. Bull. | pmid:6652817 |
Weisshaar R and Lingens F | The lipopolysaccharide of a chloridazon-degrading bacterium. | 1983 | Eur. J. Biochem. | pmid:6653551 |
Claassen E and van Rooijen N | A comparative study on the effectiveness of various procedures for attachment of two proteins (L-asparaginase and horse radish peroxidase) to the surface of liposomes. | 1983 | Prep. Biochem. | pmid:6878179 |
Jacques NA | Membrane perturbation by cerulenin modulates glucosyltransferase secretion and acetate uptake by Streptococcus salivarius. | 1983 | J. Gen. Microbiol. | pmid:6229601 |
Qian X | [Speech by Dr. Qian Xinzhong, Minister-in-charge of the State Family Planning Commission and Laureate of the United Nations Population Award, at the United Nations Population Award presentation ceremony (30 September 1983)]. | 1983 | Renkou Yanjiu | pmid:12159402 |
Williams DE et al. | Regiospecific hydroxylation of lauric acid at the (omega-1) position by hepatic and kidney microsomal cytochromes P-450 from rainbow trout. | 1984 | Arch. Biochem. Biophys. | pmid:6732245 |
Leighton F et al. | Peroxisomal fatty acid oxidation is selectively inhibited by phenothiazines in isolated hepatocytes. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6732769 |
Okita R and Chance C | Induction of laurate omega-hydroxylase by di (2-ethylhexyl)phthalate in rat liver microsomes. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6732809 |
Salaun JP et al. | Autocatalytic inactivation of plant cytochrome P-450 enzymes: selective inactivation of the lauric acid in-chain hydroxylase from Helianthus tuberosus L. by unsaturated substrate analogs. | 1984 | Arch. Biochem. Biophys. | pmid:6742847 |
Lake BG et al. | The effect of hypolipidaemic agents on peroxisomal beta-oxidation and mixed-function oxidase activities in primary cultures of rat hepatocytes. Relationship between induction of palmitoyl-CoA oxidation and lauric acid hydroxylation. | 1984 | Xenobiotica | pmid:6711016 |
Lake BG et al. | Comparative studies of the hepatic effects of di- and mono-n-octyl phthalates, di-(2-ethylhexyl) phthalate and clofibrate in the rat. | 1984 | Acta Pharmacol Toxicol (Copenh) | pmid:6720315 |
Miura Y et al. | Cytochrome P-450-dependent fatty acid hydroxylase system in Japanese house musk shrew, Suncus murinus. | 1984 | J. Biochem. | pmid:6725235 |
Harada N and Negishi M | Mouse liver testosterone 15 alpha-hydroxylase (cytochrome P-450(15) alpha). Purification, regioselectivity, stereospecificity, and sex-dependent expression. | 1984 | J. Biol. Chem. | pmid:6420405 |
Chopra IJ et al. | A competitive ligand binding assay for measurement of thyroid hormone-binding inhibitor in serum and tissues. | 1984 | J. Clin. Endocrinol. Metab. | pmid:6421865 |
Laurila H et al. | The cytochrome P450-containing monooxygenase of Trichosporon cutaneum: occurrence and properties. | 1984 | Arch. Microbiol. | pmid:6397156 |
Lamikanra A and Sholola OA | A study of the activity of soft soaps prepared from a homologous series of saturated fatty acids against cells of Escherichia coli NCTC 9001. | 1984 | Microbios | pmid:6397680 |
Chua MM et al. | Attachment of immunoglobulin to liposomal membrane via protein carbohydrate. | 1984 | Biochim. Biophys. Acta | pmid:6432057 |
Tabatabai LB and Deyoe BL | Biochemical and biological properties of soluble protein preparations from Brucella abortus. | 1984 | Dev. Biol. Stand. | pmid:6436094 |
Lake BG et al. | The effect of peroxisome proliferators on the metabolism and spectral interaction of endogenous substrates of cytochrome P-450 in rat hepatic microsomes. | 1984 | Life Sci. | pmid:6439971 |
Philipson KD | Interaction of charged amphiphiles with Na+-Ca2+ exchange in cardiac sarcolemmal vesicles. | 1984 | J. Biol. Chem. | pmid:6501286 |
Bugaut M et al. | An examination of the stereochemical course of acylation of 2-monoacylglycerols by rat intestinal villus cells using [2H3]palmitic acid. | 1984 | Biochim. Biophys. Acta | pmid:6696934 |
van der Valk PG et al. | Skin irritancy of surfactants as assessed by water vapor loss measurements. | 1984 | J. Invest. Dermatol. | pmid:6699429 |
Ortiz de Montellano PR and Reich NO | Specific inactivation of hepatic fatty acid hydroxylases by acetylenic fatty acids. | 1984 | J. Biol. Chem. | pmid:6706995 |
Kaku M et al. | Purification and characterization of cytochrome P-450 specific for prostaglandin and fatty acid hydroxylase activities from the microsomes of rabbit small intestinal mucosa. | 1984 | J. Biochem. | pmid:6530401 |
Abumrad NA et al. | Permeation of long-chain fatty acid into adipocytes. Kinetics, specificity, and evidence for involvement of a membrane protein. | 1984 | J. Biol. Chem. | pmid:6746632 |