| MeSH term | MeSH ID | Detail |
|---|---|---|
| Nephrosis, Lipoid | D009402 | 2 associated lipids |
| Vascular System Injuries | D057772 | 2 associated lipids |
| Thromboangiitis Obliterans | D013919 | 4 associated lipids |
| Bird Diseases | D001715 | 4 associated lipids |
| Cerebral Infarction | D002544 | 6 associated lipids |
| Peripheral Arterial Disease | D058729 | 7 associated lipids |
| Obesity, Morbid | D009767 | 8 associated lipids |
| Carotid Artery Injuries | D020212 | 8 associated lipids |
| Liver Diseases, Alcoholic | D008108 | 13 associated lipids |
| Vasculitis | D014657 | 14 associated lipids |
lauric acid
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
Cross Reference
Introduction
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with lauric acid?
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with lauric acid
PubChem Associated disorders and diseases
What pathways are associated with lauric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with lauric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with lauric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with lauric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with lauric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with lauric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with lauric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jacques NA | Membrane perturbation by cerulenin modulates glucosyltransferase secretion and acetate uptake by Streptococcus salivarius. | 1983 | J. Gen. Microbiol. | pmid:6229601 |
| Traul KA et al. | Two-stage carcinogenesis in vitro: transformation of 3-methylcholanthrene-initiated Rauscher murine leukemia virus-infected rat embryo cells by diverse tumor promoters. | 1981 | J. Natl. Cancer Inst. | pmid:6256572 |
| Malin-Berdel J and Valet G | Flow cytometric determination of esterase and phosphatase activities and kinetics in hematopoietic cells with fluorogenic substrates. | 1980 | Cytometry | pmid:6266787 |
| Berschauer F et al. | [Nutritive physiological effect of dietary fats in growing swine rations. 3. Effect of sunflower and coconut kernels on protein and fat retention, backfat fatty acid pattern and various blood parameters in piglets]. | 1983 | Arch Tierernahr | pmid:6370196 |
| Ramsey BL and Westphal U | Steroid-protein interactions. 40. The effect of fatty acids on progesterone binding to human serum albumin. | 1978 | Biochim. Biophys. Acta | pmid:638175 |
| Laurila H et al. | The cytochrome P450-containing monooxygenase of Trichosporon cutaneum: occurrence and properties. | 1984 | Arch. Microbiol. | pmid:6397156 |
| Lamikanra A and Sholola OA | A study of the activity of soft soaps prepared from a homologous series of saturated fatty acids against cells of Escherichia coli NCTC 9001. | 1984 | Microbios | pmid:6397680 |
| Siess MH et al. | [The effect of cholesterol and the nature of dietary fatty acids on the activities of some microsomal monooxygenases in the rat liver]. | 1983 | Reprod Nutr Dev | pmid:6405460 |
| Harada N and Negishi M | Mouse liver testosterone 15 alpha-hydroxylase (cytochrome P-450(15) alpha). Purification, regioselectivity, stereospecificity, and sex-dependent expression. | 1984 | J. Biol. Chem. | pmid:6420405 |
| Chopra IJ et al. | A competitive ligand binding assay for measurement of thyroid hormone-binding inhibitor in serum and tissues. | 1984 | J. Clin. Endocrinol. Metab. | pmid:6421865 |
| Chua MM et al. | Attachment of immunoglobulin to liposomal membrane via protein carbohydrate. | 1984 | Biochim. Biophys. Acta | pmid:6432057 |
| Tabatabai LB and Deyoe BL | Biochemical and biological properties of soluble protein preparations from Brucella abortus. | 1984 | Dev. Biol. Stand. | pmid:6436094 |
| Lake BG et al. | The effect of peroxisome proliferators on the metabolism and spectral interaction of endogenous substrates of cytochrome P-450 in rat hepatic microsomes. | 1984 | Life Sci. | pmid:6439971 |
| O'Doherty PJ | Regulation of ethanolamine and choline phosphatide biosynthesis in isolated rat intestinal villus cells. | 1980 | Can. J. Biochem. | pmid:6449990 |
| Jondorf WR and Moss MS | Radioimmunoassay technique for detecting urinary excretion products after administration of synthetic anabolic steroids to the horse. | 1978 | Xenobiotica | pmid:645104 |
| Ikeda S et al. | Effect of nicomol on high density lipoprotein (HDL) subfractions, HDL2e and HDL3e, separated by electrophoresis. | 1981 | Acta Med. Okayama | pmid:6456646 |
| Segawa A et al. | Suppression of IgE antibody response by the fatty acid-modified antigen. | 1981 | Int. Arch. Allergy Appl. Immunol. | pmid:6456998 |
| pmid:6479871 | ||||
| Guesnet P et al. | [Nutritional correction of an excess of unsaturated fatty acids in the body lipids of the growing rat]. | 1984 | Reprod Nutr Dev | pmid:6484304 |
| ZaÄtsev AN et al. | [Toxicological characteristics of disodium salt of N-lauroyl-L-glutamic acid--a surface-active agent used in the food processing industry]. | 1984 Jul-Aug | Vopr Pitan | pmid:6485298 |
| Philipson KD | Interaction of charged amphiphiles with Na+-Ca2+ exchange in cardiac sarcolemmal vesicles. | 1984 | J. Biol. Chem. | pmid:6501286 |
| Brunner G | [Progress on the way to an "artificial liver"]. | 1984 | Leber Magen Darm | pmid:6513719 |
| Takahashi K et al. | Modified lipoprotein lipase catalyzes ester synthesis in benzene. Substrate specificity. | 1984 | Enzyme | pmid:6526000 |
| Kaku M et al. | Purification and characterization of cytochrome P-450 specific for prostaglandin and fatty acid hydroxylase activities from the microsomes of rabbit small intestinal mucosa. | 1984 | J. Biochem. | pmid:6530401 |
| Fink AS et al. | Pancreatic polypeptide release by intraluminal fatty acids. | 1983 | Metab. Clin. Exp. | pmid:6621364 |
| Dailey MO and Hunter RL | Induction of cell-mediated immunity to chemically modified antigens in guinea pigs. I. Characterization of the immune response to lipid-conjugated protein antigens. | 1977 | J. Immunol. | pmid:66275 |
| Takabayashi K et al. | Coupling between fatty acid binding and sulfhydryl oxidation in bovine serum albumin. | 1983 | Eur. J. Biochem. | pmid:6628382 |
| Kimura RE et al. | Decreased oxidative metabolism in neonatal rat lung exposed to hyperoxia. | 1983 | J Appl Physiol Respir Environ Exerc Physiol | pmid:6643186 |
| Hasumura S et al. | Effects of starvation on microsomal cytochrome P-450 and laurate-omega-hydroxylation of rat kidney and liver. | 1983 | Jpn. J. Pharmacol. | pmid:6645119 |
| Kamachi S et al. | Spectrophotometric assay for lipase in serum using a chromogenic substrate, Orange I laurate. | 1983 | Chem. Pharm. Bull. | pmid:6652817 |
| Weisshaar R and Lingens F | The lipopolysaccharide of a chloridazon-degrading bacterium. | 1983 | Eur. J. Biochem. | pmid:6653551 |
| Gibson WT and Teall MR | Interactions of C12 surfactants with the skin: studies on enzyme release and percutaneous absorption in vitro. | 1983 | Food Chem. Toxicol. | pmid:6686185 |
| Bugaut M et al. | An examination of the stereochemical course of acylation of 2-monoacylglycerols by rat intestinal villus cells using [2H3]palmitic acid. | 1984 | Biochim. Biophys. Acta | pmid:6696934 |
| van der Valk PG et al. | Skin irritancy of surfactants as assessed by water vapor loss measurements. | 1984 | J. Invest. Dermatol. | pmid:6699429 |
| Ortiz de Montellano PR and Reich NO | Specific inactivation of hepatic fatty acid hydroxylases by acetylenic fatty acids. | 1984 | J. Biol. Chem. | pmid:6706995 |
| Lake BG et al. | The effect of hypolipidaemic agents on peroxisomal beta-oxidation and mixed-function oxidase activities in primary cultures of rat hepatocytes. Relationship between induction of palmitoyl-CoA oxidation and lauric acid hydroxylation. | 1984 | Xenobiotica | pmid:6711016 |
| Lake BG et al. | Comparative studies of the hepatic effects of di- and mono-n-octyl phthalates, di-(2-ethylhexyl) phthalate and clofibrate in the rat. | 1984 | Acta Pharmacol Toxicol (Copenh) | pmid:6720315 |
| Akesson B et al. | Absorption of synthetic, stereochemically defined acylglycerols in the rat. | 1978 | Lipids | pmid:672470 |
| Miura Y et al. | Cytochrome P-450-dependent fatty acid hydroxylase system in Japanese house musk shrew, Suncus murinus. | 1984 | J. Biochem. | pmid:6725235 |
| Williams DE et al. | Regiospecific hydroxylation of lauric acid at the (omega-1) position by hepatic and kidney microsomal cytochromes P-450 from rainbow trout. | 1984 | Arch. Biochem. Biophys. | pmid:6732245 |
| Leighton F et al. | Peroxisomal fatty acid oxidation is selectively inhibited by phenothiazines in isolated hepatocytes. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6732769 |
| Okita R and Chance C | Induction of laurate omega-hydroxylase by di (2-ethylhexyl)phthalate in rat liver microsomes. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6732809 |
| Salaun JP et al. | Autocatalytic inactivation of plant cytochrome P-450 enzymes: selective inactivation of the lauric acid in-chain hydroxylase from Helianthus tuberosus L. by unsaturated substrate analogs. | 1984 | Arch. Biochem. Biophys. | pmid:6742847 |
| Abumrad NA et al. | Permeation of long-chain fatty acid into adipocytes. Kinetics, specificity, and evidence for involvement of a membrane protein. | 1984 | J. Biol. Chem. | pmid:6746632 |
| Qureshi N et al. | Purification and structural determination of nontoxic lipid A obtained from the lipopolysaccharide of Salmonella typhimurium. | 1982 | J. Biol. Chem. | pmid:6749846 |
| Francis DH et al. | Characterization of immune responses of cattle to erythrocyte stroma, Anaplasma antigen, and dodecanoic acid-conjugated Anaplasma antigen: humoral immunity. | 1980 | Am. J. Vet. Res. | pmid:6768332 |
| Okita RT et al. | The omega- and (omega-1)-hydroxylase activities of prostaglandins A1 and E1 and lauric acid by pig kidney microsomes and a purified kidney cytochrome P-450. | 1981 | J. Biol. Chem. | pmid:6787046 |
| Viswanathan TS and Cushley RJ | Deuterium nuclear magnetic resonance study of the interaction of substrates and inhibitors with soybean lipoxygenase. | 1981 | J. Biol. Chem. | pmid:6788761 |
| Mortensen PB and Gregersen N | The biological origin of ketotic dicarboxylic aciduria. In vivo and in vitro investigations of the omega-oxidation of C6-C16-monocarboxylic acids in unstarved, starved and diabetic rats. | 1981 | Biochim. Biophys. Acta | pmid:6798996 |
| Gibson GG and Schenkman JB | Purification and properties of cytochrome P-450 obtained from liver microsomes of untreated rats by lauric acid affinity chromatography. | 1978 | J. Biol. Chem. | pmid:681331 |
| Wollenweber HW et al. | Fatty acid in lipopolysaccharides of Salmonella species grown at low temperature. Identification and position. | 1983 | Eur. J. Biochem. | pmid:6825685 |
| Waldeland H and Frenkel JK | Live and killed vaccines against toxoplasmosis in mice. | 1983 | J. Parasitol. | pmid:6827446 |
| Jacobsen J and Brodersen R | Albumin-bilirubin binding mechanism. | 1983 | J. Biol. Chem. | pmid:6853485 |
| Bogardus JB | Liquid crystal solubilization of cholesterol: potential method for gallstone dissolution. | 1983 | J Pharm Sci | pmid:6864466 |
| Lake BG et al. | Induction of lauric acid hydroxylation and maintenance of cytochrome P-450 content by clofibrate in primary cultures of rat hepatocytes. | 1983 | Life Sci. | pmid:6865658 |
| Fink AS et al. | Regionally perfused fatty acids augment acid-induced canine pancreatic secretion. | 1983 | Am. J. Physiol. | pmid:6869548 |
| Claassen E and van Rooijen N | A comparative study on the effectiveness of various procedures for attachment of two proteins (L-asparaginase and horse radish peroxidase) to the surface of liposomes. | 1983 | Prep. Biochem. | pmid:6878179 |
| Ohno H et al. | Improvement of the productivity of elasnin, a specific elastase inhibitor, by Streptomyces noboritoensis KM-2753. | 1980 | J. Antibiot. | pmid:6903571 |
| Grisafe JA and Hayton WL | Effects of short and medium chain fatty acids on absorption of lipophilic drugs from perfused rat intestine. | 1978 | J Pharm Sci | pmid:690822 |
| Schuster GS et al. | Anticaries and antiplaque potential of free-fatty acids in vitro and in vivo. | 1980 | Pharmacol Ther Dent | pmid:6932048 |
| Miura Y | Omega- and (omega-1)-hydroxylation of 1-dodecanol by frog liver microsomes. | 1981 | Lipids | pmid:6975411 |
| Miura Y | Effect of inhibitors on omega- and (omega-1)-hydroxylation of lauric acid by frog liver microsomes. | 1982 | Lipids | pmid:6984479 |
| Schierhorn H | [Egas Moniz, Wilhelm Löhr and cerebral angiography. An expedition into the discovery of the cerebral vessels]. | 1981 | J Hirnforsch | pmid:7035549 |
| Gibson WT | Changes in epidermal acid phosphatase levels in response to chemical irritation. | 1982 | Br. J. Dermatol. | pmid:7066188 |
| Nashima K et al. | Studies on cephalopod rhodopsin. Fatty acid esters of sucrose as effective detergents. | 1978 | Biochim. Biophys. Acta | pmid:708776 |
| Gibson GG et al. | Cytochrome P-450 induction by clofibrate. Purification and properties of a hepatic cytochrome P-450 relatively specific for the 12- and 11-hydroxylation of dodecanoic acid (lauric acid). | 1982 | Biochem. J. | pmid:7103935 |
| Salaün JP et al. | A microsomal (cytochrome P-450)-linked lauric-acid-monooxygenase from aged Jerusalem-artichoke-tuber tissues. | 1978 | Eur. J. Biochem. | pmid:710415 |
| Past MR and Cook DE | Effect of diabetes on rat liver cytochrome P-450. Evidence for a unique diabetes-dependent rat liver cytochrome P-450. | 1982 | Biochem. Pharmacol. | pmid:7150359 |
| Albers-Jackson B et al. | Incorporation of 14C acetate into the phospholipids and fatty acids of rabbit lens in organ culture. | 1982-1983 | Curr. Eye Res. | pmid:7184702 |
| Tinsley IJ et al. | Influence of dietary fatty acids on the incidence of mammary tumors in the C3H mouse. | 1981 | Cancer Res. | pmid:7214328 |
| Shimakata T and Kusaka T | Purification and characterization of 2-enoyl-CoA reductase of Mycobacterium smegmatis. | 1981 | J. Biochem. | pmid:7251572 |
| Mushtaq M et al. | Toxicological studies of a leachable stabilizer di-n-butyltin dilaurate(DBTL): effects on hepatic drug metabolizing enzyme activities. | 1981 | Drug Chem Toxicol | pmid:7261948 |
| Murnaghan MF | Effect of fatty acids on the ventricular arrhythmia threshold in the isolated heart of the rabbit. | 1981 | Br. J. Pharmacol. | pmid:7272591 |
| Wikström M | [Nobel prize laureate in chemistry]. | 1978 | Duodecim | pmid:729494 |
| Salaün JP et al. | Induction and specificity of a (cytochrome P-450)-dependent laurate in-chain-hydroxylase from higher plant microsomes. | 1981 | Eur. J. Biochem. | pmid:7308207 |
| Kusunose E et al. | Effect of cytochrome b5 on fatty acid omega- and (omega-1)-hydroxylation catalyzed by partially purified cytochrome P-450 from rabbit kidney cortex microsomes. | 1981 | J. Biochem. | pmid:7309711 |
| Ushijima T et al. | Selective and differential media for isolation and tentative identification of each species of Pityrosporum residing on normal or diseased human skin. | 1981 | Microbiol. Immunol. | pmid:7329340 |
| Charest-Boule L et al. | Influence of free fatty acid anion on the binding of warfarin to cytoplasmic proteins from rat liver. | 1980 | Chem. Biol. Interact. | pmid:7356538 |
| Francis DH et al. | Characterization of immune responses of cattle to erythrocyte stroma, Anaplasma antigen, and dodecanoic acid-conjugated Anaplasma antigen: cell-mediated immunity. | 1980 | Am. J. Vet. Res. | pmid:7369609 |
| Terada H et al. | Heat denaturation of serum albumin monitored by 1-anilino-naphthalene-8-sulfonate. | 1980 | Biochim. Biophys. Acta | pmid:7378445 |
| Bodor N et al. | Soft drugs. 1. Labile quaternary ammonium salts as soft antimicrobials. | 1980 | J. Med. Chem. | pmid:7381846 |
| Weinkam RJ et al. | Protein mediated chemical reactions of chloroethylnitrosoureas. | 1980 | Chem. Biol. Interact. | pmid:7389008 |
| Shlosberg A et al. | Poisoning of palm doves with dibutyltin dilaurate. | 1978 | J. Am. Vet. Med. Assoc. | pmid:738943 |
| Saheb SA et al. | [Effect of fatty acids on the antibacterial activity of butylated hydroxytoluene (BHT)]. | 1978 | Can. J. Microbiol. | pmid:743642 |
| Shimakata T et al. | Involvement of one of two enoyl-CoA hydratases and enoyl-CoA reductase in the acetyl-CoA-dependent elongation of medium chain fatty acids by Mycobacterium smegmatis. | 1980 | J. Biochem. | pmid:7451405 |
| Sandercock SP and Russell NJ | The elongation of exogenous fatty acids and the control of phospholipid acyl chain length in Micrococcus cryophilus. | 1980 | Biochem. J. | pmid:7470022 |
| Lee SK et al. | Defective glucose-stimulated insulin release from perifused islets of C57BL/6J mice. | 1995 | Pancreas | pmid:7479681 |
| Komata Y et al. | Accumulation of lauric acid in skin as an enhancer for the percutaneous absorption of thiamine disulfide. | 1995 | Biol. Pharm. Bull. | pmid:7493004 |
| Miura Y et al. | An analysis of the fatty acid composition of total lipids from mycoplasmas. | 1978 | Jpn. J. Exp. Med. | pmid:750678 |
| Iwami Y et al. | Effect of sucrose monolaurate on acid production, levels of glycolytic intermediates, and enzyme activities of Streptococcus mutans NCTC 10449. | 1995 | J. Dent. Res. | pmid:7560425 |
| Alterman MA et al. | Heteroatom substitution shifts regioselectivity of lauric acid metabolism from omega-hydroxylation to (omega-1)-oxidation. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7575514 |
| Yeom H et al. | The role of Thr268 in oxygen activation of cytochrome P450BM-3. | 1995 | Biochemistry | pmid:7578081 |
| Floc'h F et al. | Adjuvant and immunostimulating activities (in the absence of freund's incomplete adjuvant) of chemically modified low molecular weight mycobacterial peptidoglycans. | 1978 | Immunol. Commun. | pmid:75834 |
| Pedersen AO et al. | Effects of ionic strength and pH on the binding of medium-chain fatty acids to human serum albumin. | 1995 | Eur. J. Biochem. | pmid:7588780 |
| Tholstrup T et al. | Effect of fats high in individual saturated fatty acids on plasma lipoprotein[a] levels in young healthy men. | 1995 | J. Lipid Res. | pmid:7595068 |
| Knauf VC and Facciotti D | Genetic engineering of foods to reduce the risk of heart disease and cancer. | 1995 | Adv. Exp. Med. Biol. | pmid:7598011 |
| Takahashi N et al. | Inhibition of in vitro aflatoxin B1-DNA binding in rainbow trout by CYP1A inhibitors: alpha-naphthoflavone, beta-naphthoflavone and trout CYP1A1 peptide antibody. | 1995 | Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. | pmid:7599976 |
| Modi S et al. | NMR studies of substrate binding to cytochrome P450 BM3: comparisons to cytochrome P450 cam. | 1995 | Biochemistry | pmid:7619797 |
| Kromhout D et al. | Dietary saturated and trans fatty acids and cholesterol and 25-year mortality from coronary heart disease: the Seven Countries Study. | 1995 | Prev Med | pmid:7644455 |
| Faulkner KM et al. | Electrocatalytically driven omega-hydroxylation of fatty acids using cytochrome P450 4A1. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7644480 |