lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

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Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Nephrosis, Lipoid D009402 2 associated lipids
Vascular System Injuries D057772 2 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Bird Diseases D001715 4 associated lipids
Cerebral Infarction D002544 6 associated lipids
Peripheral Arterial Disease D058729 7 associated lipids
Obesity, Morbid D009767 8 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Vasculitis D014657 14 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

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What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

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Authors Title Published Journal PubMed Link
Chevalier G et al. Distribution study of radioactivity in rats after oral administration of the lipido/sterolic extract of Serenoa repens (Permixon) supplemented with [1-14C]-lauric acid, [1-14C]-oleic acid or [4-14C]-beta-sitosterol. 1997 Jan-Mar Eur J Drug Metab Pharmacokinet pmid:9179563
Orellana M et al. Microsomal and peroxisomal fatty acid oxidation in bile duct ligated rats: a comparative study between liver and kidney. 1997 Gen. Pharmacol. pmid:9147020
Amet Y et al. Cytochrome P450 4A and 2E1 expression in human kidney microsomes. 1997 Biochem. Pharmacol. pmid:9113097
Clementz T et al. Function of the Escherichia coli msbB gene, a multicopy suppressor of htrB knockouts, in the acylation of lipid A. Acylation by MsbB follows laurate incorporation by HtrB. 1997 J. Biol. Chem. pmid:9099672
Khosla P et al. Decreasing dietary lauric and myristic acids improves plasma lipids more favorably than decreasing dietary palmitic acid in rhesus monkeys fed AHA step 1 type diets. 1997 J. Nutr. pmid:9082040
Orellana M et al. Microsomal and peroxisomal fatty acid oxidation in streptozotocin diabetic rat liver. 1997 Gen. Pharmacol. pmid:9068973
Kragh-Hansen U et al. High-affinity binding of laurate to naturally occurring mutants of human serum albumin and proalbumin. 1996 Biochem. J. pmid:9003380
Helvig C et al. Suicide inactivation of cytochrome P450 by midchain and terminal acetylenes. A mechanistic study of inactivation of a plant lauric acid omega-hydroxylase. 1997 J. Biol. Chem. pmid:8995277
Winkler E et al. Identification of the pH sensor for nucleotide binding in the uncoupling protein from brown adipose tissue. 1997 Biochemistry pmid:8993328
Lu P et al. Heme-coordinating analogs of lauric acid as inhibitors of fatty acid omega-hydroxylation. 1997 Arch. Biochem. Biophys. pmid:8990261