lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

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Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Lung Neoplasms D008175 171 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Acne Vulgaris D000152 35 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Thrombosis D013927 49 associated lipids
Per page 10 20 50 | Total 33

PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

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Per page 10 20 50 100 | Total 1837
Authors Title Published Journal PubMed Link
Pons N et al. Interaction of polyhalogenated compounds of appropriate configuration with mammalian or bacterial CYP enzymes. Increased bilirubin and uroporphyrinogen oxidation in vitro. 2003 Biochem. Pharmacol. pmid:12907239
Kikuta Y et al. Expression and induction of cytochrome P450s in rabbit parotid glands. 2001 Biochem. Pharmacol. pmid:11389885
Sharma RK et al. Role of hepatic and renal cytochrome P-450 IVA1 in the metabolism of lipid substrates. 1989 Biochem. Pharmacol. pmid:2554928
Swinney DC et al. A novel rat hepatic clofibrate-inducible cytochrome P450 that is not a lauric acid hydroxylase. 1991 Biochem. Pharmacol. pmid:1662512
Lundgren B et al. Effects of dietary treatment with 11 dicarboxylic acids, diethylcarboxylic esters and fatty acids on peroxisomal fatty acid beta-oxidation, epoxide hydrolases and lauric acid omega-hydroxylation in mouse liver. 1992 Biochem. Pharmacol. pmid:1540233
Thomas H et al. Effect of hypolipidemic compounds on lauric acid hydroxylation and phase II enzymes. 1989 Biochem. Pharmacol. pmid:2500933
Byard J et al. Novel approaches to the purification and identification of cytochrome P450 enzymes in the equine. 1996 Biochem. Soc. Trans. pmid:8736866
Gibson GG and Bains SK Cytochrome P-450 isoenzymes involved in fatty acid metabolism. 1985 Biochem. Soc. Trans. pmid:4065418
Makowska JM et al. Species differences in the hepatic response to a potent peroxisome proliferator. 1989 Biochem. Soc. Trans. pmid:2628085
Sherrington EJ et al. Lack of effect of different dietary saturated fatty acids on adipose tissue deposition in the rat. 1996 Biochem. Soc. Trans. pmid:8736816
Abigor RD et al. Lipase-catalysed production of biodiesel fuel from some Nigerian lauric oils. 2000 Biochem. Soc. Trans. pmid:11171279
Straub P et al. Differential effects of mutations in substrate recognition site 1 of cytochrome P450 2C2 on lauric acid and progesterone hydroxylation. 1994 Biochemistry pmid:8025107
CaJacob CA and Ortiz de Montellano PR Mechanism-based in vivo inactivation of lauric acid hydroxylases. 1986 Biochemistry pmid:3490272
Haines DC et al. Crystal structure of inhibitor-bound P450BM-3 reveals open conformation of substrate access channel. 2008 Biochemistry pmid:18298086
Gasymov OK et al. Ligand binding site of tear lipocalin: contribution of a trigonal cluster of charged residues probed by 8-anilino-1-naphthalenesulfonic acid. 2008 Biochemistry pmid:18179255
Murataliev MB and Feyereisen R Functional interactions in cytochrome P450BM3. Fatty acid substrate binding alters electron-transfer properties of the flavoprotein domain. 1996 Biochemistry pmid:8942669
Murataliev MB et al. Functional interactions in cytochrome P450BM3: flavin semiquinone intermediates, role of NADP(H), and mechanism of electron transfer by the flavoprotein domain. 1997 Biochemistry pmid:9204888
Lawson RJ et al. Expression and characterization of the two flavodoxin proteins of Bacillus subtilis, YkuN and YkuP: biophysical properties and interactions with cytochrome P450 BioI. 2004 Biochemistry pmid:15449930
Sanghani PC et al. Human glutathione-dependent formaldehyde dehydrogenase. Structures of apo, binary, and inhibitory ternary complexes. 2002 Biochemistry pmid:12196016
Orlowski M et al. Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids. 1993 Biochemistry pmid:8431436