| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
lauric acid
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
Cross Reference
Introduction
To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with lauric acid?
lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with lauric acid
PubChem Associated disorders and diseases
What pathways are associated with lauric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with lauric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with lauric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with lauric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with lauric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with lauric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with lauric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Chang YT and Loew GH | Homology modeling and substrate binding study of human CYP4A11 enzyme. | 1999 | Proteins | pmid:10024026 |
| Lagrost L et al. | Variations in serum cholesteryl ester transfer and phospholipid transfer activities in healthy women and men consuming diets enriched in lauric, palmitic or oleic acids. | 1999 | Atherosclerosis | pmid:10030391 |
| Temme EH et al. | Effects of diets enriched in lauric, palmitic or oleic acids on blood coagulation and fibrinolysis. | 1999 | Thromb. Haemost. | pmid:10064003 |
| Crawford TO et al. | Abnormal fatty acid metabolism in childhood spinal muscular atrophy. | 1999 | Ann. Neurol. | pmid:10072048 |
| Haining RL et al. | Enzymatic determinants of the substrate specificity of CYP2C9: role of B'-C loop residues in providing the pi-stacking anchor site for warfarin binding. | 1999 | Biochemistry | pmid:10079071 |
| Yamazaki H and Shimada T | Effects of arachidonic acid, prostaglandins, retinol, retinoic acid and cholecalciferol on xenobiotic oxidations catalysed by human cytochrome P450 enzymes. | 1999 | Xenobiotica | pmid:10219964 |
| Richieri GV et al. | Binding kinetics of engineered mutants provide insight about the pathway for entering and exiting the intestinal fatty acid binding protein. | 1999 | Biochemistry | pmid:10231541 |
| Sabourault C et al. | Tissue-specific induction and inactivation of cytochrome P450 catalysing lauric acid hydroxylation in the sea bass, Dicentrarchus labrax. | 1999 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:10327614 |
| Bardi L et al. | Esterase activity and release of ethyl esters of medium-chain fatty acids by Saccharomyces cerevisiae during anaerobic growth. | 1998 | Can. J. Microbiol. | pmid:10347863 |
| Bardi L et al. | Saccharomyces cerevisiae cell fatty acid composition and release during fermentation without aeration and in absence of exogenous lipids. | 1999 | Int. J. Food Microbiol. | pmid:10357281 |
| Droese W et al. | Questions to the supply of young infants with fat and fatty acids. II. Fat content and fatty acid pattern in milk formulae for healthy infants in the first 6 months of life. | 1976 | Eur. J. Pediatr. | pmid:1036483 |
| Murakami K et al. | Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10403814 |
| Robinson MK et al. | A two-center study of the development of acute irritation responses to fatty acids. | 1999 | Am. J. Contact Dermatitis | pmid:10444106 |
| Goodfriend TL et al. | Plasma aldosterone, plasma lipoproteins, obesity and insulin resistance in humans. | 1999 May-Jun | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10471129 |
| Tsai YH et al. | Mechanisms mediating lipoprotein responses to diets with medium-chain triglyceride and lauric acid. | 1999 | Lipids | pmid:10574653 |
| Cazeils JL et al. | Lipid composition of hepatocyte plasma membranes from geese overfed with corn. | 1999 | Lipids | pmid:10574658 |
| Glasgow BJ et al. | Tear lipocalins: potential lipid scavengers for the corneal surface. | 1999 | Invest. Ophthalmol. Vis. Sci. | pmid:10586930 |
| Lee SH et al. | Production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) by high-cell-density cultivation of Aeromonas hydrophila. | 2000 | Biotechnol. Bioeng. | pmid:10592522 |
| Gross V et al. | Inhibition of pressure natriuresis in mice lacking the AT2 receptor. | 2000 | Kidney Int. | pmid:10620200 |
| Hoch U et al. | Structural determination of the substrate specificities and regioselectivities of the rat and human fatty acid omega-hydroxylases. | 2000 | Arch. Biochem. Biophys. | pmid:10620324 |
| Aussel L et al. | Novel variation of lipid A structures in strains of different Yersinia species. | 2000 | FEBS Lett. | pmid:10620712 |
| Nakagawa T et al. | Peroxisomal membrane protein Pmp47 is essential in the metabolism of middle-chain fatty acid in yeast peroxisomes and Is associated with peroxisome proliferation. | 2000 | J. Biol. Chem. | pmid:10652339 |
| Imaishi H et al. | Encoding of a cytochrome P450-dependent lauric acid monooxygenase by CYP703A1 specifically expressed in the floral buds of petunia hybrida. | 1999 | Biosci. Biotechnol. Biochem. | pmid:10664841 |
| Saito A et al. | Effects of capsaicin on biliary free fatty acids in rats. | 2000 | Int J Vitam Nutr Res | pmid:10683757 |
| Soetanto K and Chan M | Fundamental studies on contrast images from different-sized microbubbles: analytical and experimental studies. | 2000 | Ultrasound Med Biol | pmid:10687796 |
| Buszello K et al. | The influence of alkali fatty acids on the properties and the stability of parenteral O/W emulsions modified with solutol HS 15. | 2000 | Eur J Pharm Biopharm | pmid:10704897 |
| Tsuge T et al. | Molecular cloning of two (R)-specific enoyl-CoA hydratase genes from Pseudomonas aeruginosa and their use for polyhydroxyalkanoate synthesis. | 2000 | FEMS Microbiol. Lett. | pmid:10713420 |
| Lake BG et al. | Species differences in hepatic peroxisome proliferation, cell replication and transforming growth factor-beta1 gene expression in the rat, Syrian hamster and guinea pig. | 2000 | Mutat. Res. | pmid:10725474 |
| Sinninghe Damsté JS et al. | Structural identification of the diester preen-gland waxes of the red knot (Calidris canutus). | 2000 | J. Nat. Prod. | pmid:10757724 |
| Song B et al. | Description of strain 3CB-1, a genomovar of Thauera aromatica, capable of degrading 3-chlorobenzoate coupled to nitrate reduction. | 2000 | Int. J. Syst. Evol. Microbiol. | pmid:10758860 |
| van der Bijl P et al. | Permeation of sumatriptan through human vaginal and buccal mucosa. | 2000 | Headache | pmid:10759913 |
| Stewart JM and Blakely JA | Long chain fatty acids inhibit and medium chain fatty acids activate mammalian cardiac hexokinase. | 2000 | Biochim. Biophys. Acta | pmid:10760476 |
| Sheffield C | The new laureate speaks. | 2000 | Nature | pmid:10766219 |
| Kamm W et al. | Evaluation of absorption enhancement for a potent cyclopeptidic alpha(nu)beta(3)-antagonist in a human intestinal cell line (Caco-2). | 2000 | Eur J Pharm Sci | pmid:10767598 |
| Ayorinde FO et al. | Determination of the fatty acid composition of saponified vegetable oils using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. | 2000 | Rapid Commun. Mass Spectrom. | pmid:10775096 |
| Hong JT and Glauert HP | Effect of extracellular matrix on the expression of peroxisome proliferation associated genes in cultured rat hepatocytes. | 2000 | Toxicol In Vitro | pmid:10793296 |
| Govender T et al. | Defining the drug incorporation properties of PLA-PEG nanoparticles. | 2000 | Int J Pharm | pmid:10794931 |
| Sulikowski GA et al. | Investigations into a biomimetic approach toward CP-225,917 and CP-263,114. | 2000 | J. Org. Chem. | pmid:10813939 |
| Hsu AF et al. | Immobilization of Pseudomonas cepacia lipase in a phyllosilicate sol-gel matrix: effectiveness as a biocatalyst. | 2000 | Biotechnol. Appl. Biochem. | pmid:10814587 |
| Casolo V et al. | The role of mild uncoupling and non-coupled respiration in the regulation of hydrogen peroxide generation by plant mitochondria. | 2000 | FEBS Lett. | pmid:10828450 |
| Dong GC et al. | Preparation and characterization of surface-modified calcium hydrogenphosphate by hexamethylene diisocyanates. | 2000 | Biomed Sci Instrum | pmid:10834217 |
| Arrol S et al. | The effects of fatty acids on apolipoprotein B secretion by human hepatoma cells (HEP G2). | 2000 | Atherosclerosis | pmid:10856517 |
| Kawashima H et al. | Human fatty acid omega-hydroxylase, CYP4A11: determination of complete genomic sequence and characterization of purified recombinant protein. | 2000 | Arch. Biochem. Biophys. | pmid:10860550 |
| Hoch U et al. | Molecular basis for the omega-regiospecificity of the CYP4A2 and CYP4A3 fatty acid hydroxylases. | 2000 | J. Biol. Chem. | pmid:10869363 |
| Ohk SH and Kuramitsu HK | A novel antibacterial agent derived from the C-terminal domain of streptococcus mutans GTP-binding protein. | 2000 | J. Antimicrob. Chemother. | pmid:10882696 |
| Champlin R and Hunter RL | Studies on the composition of adjuvants which selectively enhance delayed-type hypersensitivity to lipid conjugated protein antigens. | 1975 | J. Immunol. | pmid:1089714 |
| Tang L et al. | A kinetic study of the synthesis of ascorbate fatty acid esters catalysed by immobilized lipase in organic media. | 2000 | Biotechnol. Appl. Biochem. | pmid:10918036 |
| Ogiso T et al. | Percutaneous penetration of ozagrel and the enhancement produced by saturated fatty acids. | 2000 | Biol. Pharm. Bull. | pmid:10919364 |
| Imai Y et al. | Unique heme environment at the putative distal region of hydrogen peroxide-dependent fatty acid alpha-hydroxylase from Sphingomonas paucimobilis (peroxygenase P450(SPalpha). | 2000 | J. Biochem. | pmid:10920253 |
| Samartsev VN et al. | Comparative study on uncoupling effects of laurate and lauryl sulfate on rat liver and skeletal muscle mitochondria. | 2000 | Biochim. Biophys. Acta | pmid:10924910 |
| Saffert A et al. | A dual function alpha-dioxygenase-peroxidase and NAD(+) oxidoreductase active enzyme from germinating pea rationalizing alpha-oxidation of fatty acids in plants. | 2000 | Plant Physiol. | pmid:10938370 |
| Santoyo S and Ygartua P | Effect of skin pretreatment with fatty acids on percutaneous absorption and skin retention of piroxicam after its topical application. | 2000 | Eur J Pharm Biopharm | pmid:10962234 |
| Hashemi E et al. | Stability of cytochrome P450 proteins in cultured precision-cut rat liver slices. | 2000 | Toxicology | pmid:10967402 |
| Toshima Y et al. | A new model of cerebral microthrombosis in rats and the neuroprotective effect of a Rho-kinase inhibitor. | 2000 | Stroke | pmid:10978059 |
| Giorgi M et al. | Cytochrome P450-dependent monooxygenase activities and their inducibility by classic P450 inducers in the liver, kidney, and nasal mucosa of male adult ring-necked pheasants. | 2000 | Toxicol. Appl. Pharmacol. | pmid:10986015 |
| Imaishi H et al. | CYP78A1 preferentially expressed in developing inflorescences of Zea mays encoded a cytochrome P450-dependent lauric acid 12-monooxygenase. | 2000 | Biosci. Biotechnol. Biochem. | pmid:10993158 |
| Nielsen AD et al. | Thermochemistry of the specific binding of C12 surfactants to bovine serum albumin. | 2000 | Biochim. Biophys. Acta | pmid:11004550 |
| DeLany JP et al. | Differential oxidation of individual dietary fatty acids in humans. | 2000 | Am. J. Clin. Nutr. | pmid:11010930 |
| Sidhu SS et al. | Fatty acid-induced cholecystokinin secretion and changes in intracellular Ca2+ in two enteroendocrine cell lines, STC-1 and GLUTag. | 2000 | J. Physiol. (Lond.) | pmid:11018115 |
| Vogel S et al. | Characterization of a new member of the fatty acid-binding protein family that binds all-trans-retinol. | 2001 | J. Biol. Chem. | pmid:11022035 |
| Pereira JR et al. | Inversion in the change of the refractive index and memory effect near the nematic-isotropic phase transition in a lyotropic liquid crystal. | 2000 | Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics | pmid:11031592 |
| Buhler DR et al. | Effects of 17beta-estradiol and testosterone on hepatic mRNA/protein levels and catalytic activities of CYP2M1, CYP2K1, and CYP3A27 in rainbow trout (Oncorhynchus mykiss). | 2000 | Toxicol. Appl. Pharmacol. | pmid:11032764 |
| Yang YH et al. | Heterologous expression of CYP2K1 and identification of the expressed protein (BV-CYP2K1) as lauric acid (omega-1)-hydroxylase and aflatoxin B1 exo-epoxidase. | 2000 | Drug Metab. Dispos. | pmid:11038153 |
| Soetanto K and Chan M | Study on the lifetime and attenuation properties of microbubbles coated with carboxylic acid salts. | 2000 | Ultrasonics | pmid:11106009 |
| Loughran PA et al. | Identification of unique amino acids that modulate CYP4A7 activity. | 2000 | Biochemistry | pmid:11106489 |
| Pantaler E et al. | Acceleration of phospholipid flip-flop in the erythrocyte membrane by detergents differing in polar head group and alkyl chain length. | 2000 | Biochim. Biophys. Acta | pmid:11118549 |
| Morais PC et al. | Raman spectroscopy in magnetic fluids. | 2001 | Biomol. Eng. | pmid:11163750 |
| Oh HJ et al. | Effects of vehicles and enhancers on transdermal delivery of melatonin. | 2001 | Int J Pharm | pmid:11165821 |
| Larson TR and Graham IA | Technical Advance: a novel technique for the sensitive quantification of acyl CoA esters from plant tissues. | 2001 | Plant J. | pmid:11169187 |
| Abigor RD et al. | Lipase-catalysed production of biodiesel fuel from some Nigerian lauric oils. | 2000 | Biochem. Soc. Trans. | pmid:11171279 |
| Kikuta Y et al. | Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14. | 2000 | Arch. Biochem. Biophys. | pmid:11185557 |
| Byrdwell WC and Neff WE | Autoxidation products of normal and genetically modified canola oil varieties determined using liquid chromatography with mass spectrometric detection. | 2001 | J Chromatogr A | pmid:11206810 |
| Wiberg E et al. | The distribution of caprylate, caprate and laurate in lipids from developing and mature seeds of transgenic Brassica napus L. | 2000 | Planta | pmid:11219581 |
| Coon J and Hunter R | Properties of conjugated protein immunogens which selectively stimulate delayed-type hypersensitivity. | 1975 | J. Immunol. | pmid:1123546 |
| Ngo S et al. | Cytochrome P450 4A, peroxisomal enzymes and nicotinamide cofactors in koala liver. | 2000 | Comp. Biochem. Physiol. C Toxicol. Pharmacol. | pmid:11246504 |
| Kantor HL and Prestegard JH | Fusion of fatty acid containing lecithin vesicles. | 1975 | Biochemistry | pmid:1125198 |
| Jørgensen JR et al. | In vivo absorption of medium-chain fatty acids by the rat colon exceeds that of short-chain fatty acids. | 2001 | Gastroenterology | pmid:11266379 |
| Lee JY et al. | Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4. | 2001 | J. Biol. Chem. | pmid:11278967 |
| Vessey DA | Isolation and preliminary characterization of the medium-chain fatty acid:CoA ligase responsible for activation of short- and medium-chain fatty acids in colonic mucosa from swine. | 2001 | Dig. Dis. Sci. | pmid:11281196 |
| Orellana B M et al. | Oxidative stress, microsomal and peroxisomal fatty acid oxidation in the liver of rats treated with acetone. | 2001 | Comp. Biochem. Physiol. C Toxicol. Pharmacol. | pmid:11301292 |
| Aoki T et al. | Cholesterol-lowering effect of NK-104, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, in guinea pig model of hyperlipidemia. | 2001 | Arzneimittelforschung | pmid:11304935 |
| Echtay KS et al. | Role of intrahelical arginine residues in functional properties of uncoupling protein (UCP1). | 2001 | Biochemistry | pmid:11318647 |
| Cunha MT et al. | Effect of salts and surfactants on the partitioning of Fusarium solani pisi cutinase in aqueous two-phase systems of thermoseparating ethylene oxide/propylene oxide random copolymer and hydroxypropyl starch. | 2000 | Bioseparation | pmid:11321518 |
| Glover ED | 2000 Research Laureate Medallion Award. | Am J Health Behav | pmid:11322613 | |
| Simonyan RA et al. | Cold-induced changes in the energy coupling and the UCP3 level in rodent skeletal muscles. | 2001 | Biochim. Biophys. Acta | pmid:11334791 |
| Stott PW et al. | Mechanistic study into the enhanced transdermal permeation of a model beta-blocker, propranolol, by fatty acids: a melting point depression effect. | 2001 | Int J Pharm | pmid:11337176 |
| Ichihara K et al. | Fatty acid omega and (omega-1)-Hydroxylation in rabbit intestinal mucosa microsomes. | 1979 | J. Biochem. | pmid:113393 |
| Kothari HV | Purification and properties of aortic cholesteryl ester hydrolase. | 1975 | Lipids | pmid:1134220 |
| Park SJ et al. | Biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyvalerate-co-3-hydroxyhexanoate) by metabolically engineered Escherichia coli strains. | 2001 | Biotechnol. Bioeng. | pmid:11353413 |
| Loughran PA et al. | The kinetic and spectral characterization of the E. coli-expressed mammalian CYP4A7: cytochrome b5 effects vary with substrate. | 2001 | Arch. Biochem. Biophys. | pmid:11368012 |
| Cowart LA et al. | Structural determinants of active site binding affinity and metabolism by cytochrome P450 BM-3. | 2001 | Arch. Biochem. Biophys. | pmid:11368173 |
| Kragh-Hansen U et al. | Detergents as probes of hydrophobic binding cavities in serum albumin and other water-soluble proteins. | 2001 | Biophys. J. | pmid:11371462 |
| Liebau M et al. | Bioadhesion of supramolecular structures at supported planar bilayers as studied by the quartz crystal microbalance. | 2001 | Eur. Biophys. J. | pmid:11372532 |
| Kikuta Y et al. | Expression and induction of cytochrome P450s in rabbit parotid glands. | 2001 | Biochem. Pharmacol. | pmid:11389885 |
| van Roermund CW et al. | Identification of a peroxisomal ATP carrier required for medium-chain fatty acid beta-oxidation and normal peroxisome proliferation in Saccharomyces cerevisiae. | 2001 | Mol. Cell. Biol. | pmid:11390660 |
| Amet Y et al. | Adaptation to chronic ethanol administration emphasized by fatty acid hydroxylations in rat liver and kidney microsomes. | 2000 | Eur J Nutr | pmid:11395987 |
| Gilep AA et al. | Reconstitution of the enzymatic activities of cytochrome P450s using recombinant flavocytochromes containing rat cytochrome b(5) fused to NADPH--cytochrome P450 reductase with various membrane-binding segments. | 2001 | Arch. Biochem. Biophys. | pmid:11396924 |
| Imaoka S et al. | A transgenic mouse expressing human CYP4B1 in the liver. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11396967 |
| Bartolotta S et al. | Effect of fatty acids on arenavirus replication: inhibition of virus production by lauric acid. | 2001 | Arch. Virol. | pmid:11402863 |